Initiation of human parturition. III. Fetal membrane content of prostaglandin E2 and F2alpha precursor.

Abstract:

:Unesterified arachidonic acid is the obligatory precursor of the prostaglandins (PG), PGF2alpha and PGE2. In order to ascertain whether or not the human fetal membranes could represent a storage site for prostaglandin(s) precursor, the fatty acid content of human fetal membranes was measured. Approximately 20% of the fatty acids found in fetal membranes obtained from near-term, non-laboring women was arachidonic acid, whereas only 0.4% of the fatty acids of the parietal peritoneum of the mother is arachidonic acid. A small but significant decrease in the arachidonic acid concentration was found in the fetal membranes obtained from laboring women compared to that found prior to labor. On the other hand, the concentration of palmitic acid was increased in membranes obtained during labor while no significant changes in concentration in the remaining fatty acids were observed in membranes from laboring compared to non-laboring near-term gravidas. The significance of these observations in relation to the availability of prostaglandin precursor and the initiation of human parturition is considered.

journal_name

Obstet Gynecol

authors

Schwarz BE,Schultz FM,Macdonald PC,Johnston JM

subject

Has Abstract

pub_date

1975-11-01 00:00:00

pages

564-8

issue

5

eissn

0029-7844

issn

1873-233X

journal_volume

46

pub_type

杂志文章
  • Genetic polymorphisms and spontaneous preterm birth.

    abstract:OBJECTIVE:To examine whether selected genetic polymorphisms in the infant are associated with spontaneous preterm birth (less than 37 weeks) among children with or without later-diagnosed cerebral palsy. METHODS:Exploratory case-control study investigating the relationship of gestational age at delivery to 31 single n...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000252712.62241.1a

    authors: Gibson CS,MacLennan AH,Dekker GA,Goldwater PN,Dambrosia JM,Munroe DJ,Tsang S,Stewart C,Nelson KB

    更新日期:2007-02-01 00:00:00

  • Risk of large-for-gestational-age newborns in women with gestational diabetes by race and ethnicity and body mass index categories.

    abstract:OBJECTIVE:To compare the prevalence of large-for-gestational-age (LGA) newborns across categories of body mass index (BMI) in five racial and ethnic groups. METHODS:This cohort study examined 7,468 women with gestational diabetes mellitus (GDM) who delivered a live newborn between 1995 and 2006 at Kaiser Permanente No...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e318291b15c

    authors: Sridhar SB,Ferrara A,Ehrlich SF,Brown SD,Hedderson MM

    更新日期:2013-06-01 00:00:00

  • Amniotic fluid optical density and neonatal respiratory outcome.

    abstract::A simple, rapid, economical, and accurate test to assess fetal pulmonary maturity on a 24-hour basis, 7 days a week, is urgently needed. A 15-minute test has been developed that correlates well with fetal pulmonary maturity. Optical density (OD) readings at 650 nm of greater than or equal to 0.15 in pigment-free, cent...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Cetrulo CL,Sbarra AJ,Selvaraj RJ,Kappy KA,Herschel MJ,Knuppel RJ,Ingardia CJ,Kennedy JL,Mitchell GW

    更新日期:1980-02-01 00:00:00

  • The development of fetal heart rate patterns during normal pregnancy.

    abstract::Characteristics of the fetal heart rate (FHR) were studied longitudinally throughout the second and third trimesters in 43 low-risk singleton fetuses. The second trimester was characterized by an FHR pattern showing minimal differences between quiet and active intervals of fetal behavior. Few movements were accompanie...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/00006250-199011000-00017

    authors: Pillai M,James D

    更新日期:1990-11-01 00:00:00

  • Estrogen improves psychological function in asymptomatic postmenopausal women.

    abstract::Estrogen treatment of postmenopausal women has been suggested to improve mood and psychological function. However, this remains controversial because previous studies involved heterogeneous groups, were not double blind, and included women who were also experiencing somatic symptoms that were relieved by estrogen. A r...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Ditkoff EC,Crary WG,Cristo M,Lobo RA

    更新日期:1991-12-01 00:00:00

  • Maternal Pulse Pressure and the Risk of Postepidural Complications: A Randomized Controlled Trial.

    abstract:OBJECTIVE:To test the hypothesis that increasing the intravenous fluid bolus volume at the time of epidural placement in women with narrow pulse pressure would reduce postepidural fetal heart rate (FHR) abnormalities, hypotension, and resuscitative obstetric interventions. METHODS:We performed a single-center randomiz...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/AOG.0000000000002326

    authors: Lappen JR,Myers SA,Bolen N,Mercer BM,Chien EKS

    更新日期:2017-12-01 00:00:00

  • Elevated second-trimester maternal serum hCG: a marker of inadequate angiogenesis.

    abstract:OBJECTIVE:To measure angiogenin, a potent inducer of neovascularization and interleukin-6, as an indicator of acute inflammation, in second-trimester amniotic fluid of patients with elevated maternal serum hCG. METHODS:In this case-control study, 20 patients with elevated maternal serum hCG (at least 2.0 multiples of ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(98)00010-6

    authors: Spong CY,Ghidini A,Dildy GA,Loucks CA,Varner MW,Pezzullo JC

    更新日期:1998-04-01 00:00:00

  • Flow cytometry of peritoneal washings in gynecologic neoplasia.

    abstract::A prospective, double blind study was initiated to compare flow cytometry to cytopathology in detecting malignant cells within peritoneal washings. Deoxyribonucleic acid (DNA) histograms were generated using 4',6-diamidino-2-phenylindole (DAPI) as a DNA fluorochrome. Evaluation of these data revealed a correlation of ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/00006250-198605000-00014

    authors: Lovecchio JL,Budman DR,Susin M,Grueneberg D,Fenton AN

    更新日期:1986-05-01 00:00:00

  • Clinical chorioamnionitis and histologic placental inflammation.

    abstract:OBJECTIVE:To estimate the rate of histologic chorioamnionitis in the presence of diagnosed clinical chorioamnionitis and determine whether clinical markers of maternal and neonatal infection are associated with histologic chorioamnionitis. METHODS:We identified singleton pregnancies from 1996 in which discharge diagno...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(99)00416-0

    authors: Smulian JC,Shen-Schwarz S,Vintzileos AM,Lake MF,Ananth CV

    更新日期:1999-12-01 00:00:00

  • Influence of an "opt-out" test strategy and patient factors on human immunodeficiency virus screening in pregnancy.

    abstract:OBJECTIVE:To estimate both human immunodeficiency virus (HIV) testing acceptance rates in pregnancy using an opt-out policy and patient characteristics influencing acceptance. METHODS:At the first prenatal visit, HIV testing was offered using an opt-out approach. Reasons for refusing testing were explored. Demographic...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000267497.39041.06

    authors: Yudin MH,Moravac C,Shah RR

    更新日期:2007-07-01 00:00:00

  • High-fiber diet for treatment of constipation in women with pelvic floor disorders.

    abstract:OBJECTIVE:To examine the effect of high-fiber diet on constipation in women with pelvic floor disorders. METHODS:This was a study of a prospective cohort of 41 consecutive women presenting to a tertiary care facility for pelvic floor disorders with a complaint of constipation from March 2005 to September of 2005. Pati...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000308660.48204.7f

    authors: Shariati A,Maceda JS,Hale DS

    更新日期:2008-04-01 00:00:00

  • Antenatal evaluation and management in nonimmune hydrops fetalis.

    abstract::Thirty-eight cases of nonimmune hydrops fetalis were evaluated by detailed real-time ultrasonography and two-dimensional echocardiography. Before ultrasound evaluation, all mothers had a complete blood count, titers for toxoplasmosis, rubella, cytomegalovirus, and herpes (TORCH screen), serum albumin, and a Kleihauer-...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Watson J,Campbell S

    更新日期:1986-04-01 00:00:00

  • Pregnancy after myocardial infarction: are we playing safe?

    abstract::The safety of pregnancy after myocardial infarction remains a significant dilemma for both the obstetrician and the cardiologist. Only 20 cases of pregnancy after myocardial infarction have been reported. To clarify this problem, we add our experience of four such cases in which conception occurred 9 months to 9 years...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Frenkel Y,Barkai G,Reisin L,Rath S,Mashiach S,Battler A

    更新日期:1991-06-01 00:00:00

  • XY gonadal dysgenesis: aberrant testicular differentiation in the presence of H-Y antigen.

    abstract::Six patients with pure nonmosaic 46,XY gonadal dysgenesis (XY GD) and histocompatibility H-Y antigen titers in the normal male range (H-Y+) are presented. Clinical characteristics included a female phenotype, masculine skeletal characteristics, signs of virilization, and primary amenorrhea. All individuals had unambig...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Moltz L,Schwartz U,Pickartz H,Hammerstein J,Wolf U

    更新日期:1981-07-01 00:00:00

  • The management of severe preeclampsia and eclampsia with intravenous diazoxide.

    abstract::Twelve patients with either severe preeclampsia (9) or eclampsia (3) were treated with intravenous diazoxide, 300-mg bolus, for the reduction of diastolic blood pressure (less than or equal 110 torr) after the usual and customary measures had been initiated to include parenteral MgSO4 and diazepam. Diazoxide precipito...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Morris JA,Arce JJ,Hamilton CJ,Davidson EC,Maidman JE,Clark JH,Bloom RS

    更新日期:1977-06-01 00:00:00

  • Factors predicting successful labor induction.

    abstract:OBJECTIVE:To evaluate maternal parity, the sonographic measurement of cervical length, and the five components of the Bishop score to determine which factors best predict the length of latent-phase labor in women undergoing labor induction. METHODS:Cervical position, cervical consistency, cervical effacement, cervical...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(96)00321-3

    authors: Watson WJ,Stevens D,Welter S,Day D

    更新日期:1996-12-01 00:00:00

  • Reassessing the Duration of the Second Stage of Labor in Relation to Maternal and Neonatal Morbidity.

    abstract:OBJECTIVE:To assess the morbidity associated with continuing the second-stage duration of labor, weighing the probability of spontaneous vaginal birth without morbidity compared with birth with serious maternal or neonatal complications. METHODS:In a retrospective cohort, we analyzed singleton, vertex births at 36 wee...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000002431

    authors: Grantz KL,Sundaram R,Ma L,Hinkle S,Berghella V,Hoffman MK,Reddy UM

    更新日期:2018-02-01 00:00:00

  • Risk factors for pelvic organ prolapse repair after hysterectomy.

    abstract:OBJECTIVE:To estimate the incidence and identify the risk factors for pelvic organ prolapse repair after hysterectomy. METHODS:We conducted a case-control study. We identified 6,214 women who underwent hysterectomy in our gynecology department from 1982 to 2002. Cases (n=114) were women who required pelvic organ prola...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000278567.37925.4e

    authors: Dällenbach P,Kaelin-Gambirasio I,Dubuisson JB,Boulvain M

    更新日期:2007-09-01 00:00:00

  • Rhabdomyolysis After Hyperemesis Gravidarum.

    abstract:BACKGROUND:Hyperemesis gravidarum may lead to hypovolemia and substantial electrolyte abnormalities, including hypokalemia. Hypokalemia, when profound, may result in rare consequences, such as rhabdomyolysis. CASE:A 20-year-old woman with hyperemesis gravidarum at 19 weeks of gestation presented with extreme leg weakn...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000001418

    authors: Lassey SC,Robinson JN

    更新日期:2016-07-01 00:00:00

  • The effect of preterm birth on umbilical cord blood gases.

    abstract::Apgar scores are used routinely to assess early neonatal status, but are less accurate in the preterm neonate because of developmental immaturity. Attention has been directed to umbilical cord gases as a method of neonatal evaluation. Using a retrospective chart review of all viable preterm births (24-36 weeks' gestat...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Dickinson JE,Eriksen NL,Meyer BA,Parisi VM

    更新日期:1992-04-01 00:00:00

  • Reclosure of the disrupted laparotomy wound: a systematic review.

    abstract:OBJECTIVE:To review systematically all prospective, randomized trials published in English quantifying the success of reclosure of the disrupted laparotomy wound. DATA SOURCES:The MEDLINE/PubMed, EMBASE, CINAHL, and Cochrane databases were searched from 1966 to 2004. References were hand-searched and their authors con...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/01.AOG.0000171114.75338.06

    authors: Wechter ME,Pearlman MD,Hartmann KE

    更新日期:2005-08-01 00:00:00

  • Pitfalls in the diagnosis of endometrial neoplasia.

    abstract::One hundred consecutive cases of hyperplasia of the endometrium were referred to the Sloane Hospital for Women. The referral diagnoses and consultation diagnoses were compared for the purpose of analyzing common diagnostic problems in interpretation of endometrial hyperplasias and the use of diagnostic terminology as ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Winkler B,Alvarez S,Richart RM,Crum CP

    更新日期:1984-08-01 00:00:00

  • Leuprolide acetate in the management of ureteral obstruction caused by endometriosis.

    abstract::Endometriotic ureteral obstruction is a serious event commonly diagnosed late and therefore associated with a major risk of hydronephrotic renal atrophy. The standard therapy is surgical. However, medical treatment has been reported using danazol, progestins, and estrogen-progestin combinations, although solid documen...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Rivlin ME,Miller JD,Krueger RP,Patel RB,Bower JD

    更新日期:1990-03-01 00:00:00

  • Laser therapy of genital condylomata acuminata.

    abstract::The effectiveness of the carbon dioxide laser was evaluated in the treatment of penile, anorectal, and urethral condylomata acuminata in 40 men. All but six cases of urethral condylomata were prior conventional treatment failures. Postlaser follow-up ranged between one and two years, with an average of 16 months. No p...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Ferenczy A

    更新日期:1984-05-01 00:00:00

  • Avoiding transmitting identified mutations to offspring using preimplantation genetic diagnosis.

    abstract:BACKGROUND:Preimplantation genetic diagnosis has been used to decrease or avoid the risk of transmitting identified mutations to offspring. CASE:A 29-year-old woman with spondyloepiphyseal dysplasia congenita and her 30-year-old husband with Marfan syndrome underwent in vitro fertilization with preimplantation genetic...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e3181c9b316

    authors: Smith LP,Hughes MR,Thirumoorthi I,Proud VK,Penzias AS

    更新日期:2010-02-01 00:00:00

  • Reduction of the disintegrin and metalloprotease ADAM12 in preeclampsia.

    abstract:OBJECTIVES:The secreted form of ADAM12 is a metalloprotease that may be involved in placental and fetal growth. We examined whether the concentration of ADAM12 in first-trimester maternal serum could be used as a marker for preeclampsia. METHODS:We developed a semiautomated, time-resolved, immunofluorometric assay for...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000165829.65319.65

    authors: Laigaard J,Sørensen T,Placing S,Holck P,Fröhlich C,Wøjdemann KR,Sundberg K,Shalmi AC,Tabor A,Nørgaard-Pedersen B,Ottesen B,Christiansen M,Wewer UM

    更新日期:2005-07-01 00:00:00

  • Understanding risk: a randomized controlled trial of communicating contraceptive effectiveness.

    abstract:OBJECTIVE:To determine which of three different approaches increased women's understanding of risk of pregnancy associated with different contraceptive methods. METHODS:We randomly assigned 461 reproductive-age women to one of three tables presenting pregnancy risk (Food and Drug Administration table with numbers, Wor...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0029-7844(03)00662-8

    authors: Steiner MJ,Dalebout S,Condon S,Dominik R,Trussell J

    更新日期:2003-10-01 00:00:00

  • Ovarian hyperstimulation syndrome caused by pituitary gonadotroph adenoma secreting follicle-stimulating hormone.

    abstract:BACKGROUND:We report a highly exceptional case in which a gonadotroph adenoma was diagnosed in a patient with normal follicle-stimulating hormone (FSH) levels. CASE:A 30-year-old woman with a gonadotroph adenoma presented with hyperstimulation syndrome and normal FSH levels. After treatment of her adenoma she had regu...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000247316.60573.4a

    authors: Ghayuri M,Liu JH

    更新日期:2007-02-01 00:00:00

  • Analysis of McRoberts' maneuver by x-ray pelvimetry.

    abstract:OBJECTIVE:To document radiographically the changes in pelvic dimensions created by McRoberts' maneuver. METHODS:Women at least 37 weeks' pregnant who presented to labor and delivery were eligible for study entry. Anterior-posterior and lateral x-rays were taken with women in the dorsal lithotomy position and after app...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(99)00445-7

    authors: Gherman RB,Tramont J,Muffley P,Goodwin TM

    更新日期:2000-01-01 00:00:00

  • Anaphylactoid syndrome after intrauterine pressure catheter placement.

    abstract:BACKGROUND:Anaphylactoid syndrome of pregnancy is a rare and poorly understood complication of pregnancy. Intrauterine pressure catheter placement is a procedure routinely performed in labor and delivery that is traditionally associated with few complications. CASE:A pregnant woman at term experienced anaphylactoid sy...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e3181b5c8cc

    authors: Harbison L,Bell L

    更新日期:2010-02-01 00:00:00