Levels of glycosaminoglycans in peri-implant sulcus fluid as a means of monitoring bone response to endosseous dental implants.

Abstract:

:The presence of certain glycosaminoglycans in peri-implant sulcus fluid may be an effective means of monitoring changes in bone metabolic activity following initial loading of implant abutments. This study has investigated levels of chondroitin 4 sulphate and hyaluronan in peri-implant sulcus fluid from titanium osseointegrated implants following initial abutment placement and exposure to masticatory stresses. Abutments were placed after a 3-month osseointegration period post-initial surgical placement of the interosseous stage. 10 edentulous patients, each with 5 mandibular implants were reviewed at 2, 4, 6 and 8 days after abutment placement. Clinical details were assessed and recorded and sulcus fluid collected in microcapillary tubes for a 5-min period for each abutment. Levels of glycosaminoglycans were assessed using cellulose acetate electrophoresis and densitometric scanning of alcian blue stained strips against known glycosaminoglycan standards. Maximum levels of sulcus fluid (0.3-1.25 microliters/5 min) were evident at 4 days with a decrease towards 8 days. Levels of sulphated glycosaminoglycans were also maximal at 2-4 days (range 0.03 - 0.126 micrograms/5 min) and decreased at 6-8 days. Hyaluronan was detected within a similar range of values reaching maximal levels at 4 days and decreasing by 8 days. The results indicate that glycosaminoglycan levels of peri-implant sulcus fluid is an effective means of measuring and maintaining changes in bone metabolism. The absence of proteodermatan sulphate precludes soft tissues being a source of these markers.

journal_name

Clin Oral Implants Res

authors

Beck CB,Embery G,Langley MS,Waddington RJ

doi

10.1034/j.1600-0501.1991.020404.x

subject

Has Abstract

pub_date

1991-10-01 00:00:00

pages

179-85

issue

4

eissn

0905-7161

issn

1600-0501

journal_volume

2

pub_type

杂志文章
  • Evaluation of peri-implant buccal bone by computed tomography: an experimental study.

    abstract:OBJECTIVES:To evaluate the accuracy of measuring peri-implant buccal bone when using three different computed tomography devices. MATERIALS AND METHODS:Sixty tissue-level or bone-level dental implants were placed in bovine ribs with either buccal bone full coverage, dehiscence or fenestration. For each site, the dista...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12663

    authors: González-Martín O,Oteo C,Ortega R,Alandez J,Sanz M,Veltri M

    更新日期:2016-08-01 00:00:00

  • Prosthetic restoration in the single-tooth gap: patient preferences and analysis of the WTP index.

    abstract:OBJECTIVE:The objective of this study was to evaluate the preference of a patients' population, according to the index of willingness to pay (WTP), against two treatments to restore a single-tooth gap: the implant-supported crown (ISC) and the 3-unit fixed partial denture prosthesis (FPDP) on natural teeth. MATERIALS ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12264

    authors: Augusti D,Augusti G,Re D

    更新日期:2014-11-01 00:00:00

  • The platform switching concept revisited. An experimental study in dogs.

    abstract:OBJECTIVE:To evaluate the influence of the configuration of the marginal aspect of implants placed immediately into extraction sockets on peri-implant hard tissue adaptation. MATERIAL AND METHODS:In 6 Labrador dogs, endodontic treatments of the mesial roots of 1 M1 were performed and the distal roots were removed. 2 P...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12262

    authors: Bressan E,Lang NP,Corazza B,Ricci S,Almagro Urrutia Z,Botticelli D

    更新日期:2014-10-01 00:00:00

  • Immediate functional loading of Brånemark single tooth implants. An 18 months' clinical pilot follow-up study.

    abstract::A clinical and radiographical study was performed to evaluate the treatment outcome of single tooth replacements with artificial crowns retained to implants installed according to a 1-stage surgical procedure and immediate loading (Experimental Group = EG) in comparison to the original 2-stage concept (Control Group =...

    journal_title:Clinical oral implants research

    pub_type: 临床试验,杂志文章

    doi:10.1034/j.1600-0501.2000.011001026.x

    authors: Ericsson I,Nilson H,Lindh T,Nilner K,Randow K

    更新日期:2000-02-01 00:00:00

  • Comparing bar and double-crown attachments in implant-retained prosthetic reconstruction: a follow-up investigation.

    abstract:OBJECTIVES:A removable implant-retained dental prosthesis in an edentulous mandible can use telescopic crowns or a bar superstructure as anchorage elements for an overdenture. The aim of this study was to compare the clinical results for bar-anchored and telescopic crown-retained overdentures in implant prosthetic trea...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0501.2007.01500.x

    authors: Eitner S,Schlegel A,Emeka N,Holst S,Will J,Hamel J

    更新日期:2008-05-01 00:00:00

  • IL-1 gene polymorphism and smoking as risk factors for peri-implant bone loss in a well-maintained population.

    abstract::The aim of the present study was (i) to investigate the relation between specific interleukin-1 (IL-1) gene polymorphisms and peri-implant bone loss at osseointegrated ITI(R) dental implants and (ii) to explore the association between these allelic variants of the IL-1 gene complex and peri-implant mucosal inflammatio...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.2003.140102.x

    authors: Feloutzis A,Lang NP,Tonetti MS,Bürgin W,Brägger U,Buser D,Duff GW,Kornman KS

    更新日期:2003-02-01 00:00:00

  • Influence of barrier occlusiveness on guided bone augmentation. An experimental study in the rat.

    abstract::The present study was designed to test perforated and non-perforated barriers for their ability to promote augmentation of bone tissue. More specifically, 1 totally occlusive barrier and 6 barriers with perforation sizes of about 10, 25, 50, 75, 100, and 300 microns and 1 group with no barriers placed (open test chamb...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.1998.090406.x

    authors: Lundgren A,Lundgren D,Taylor A

    更新日期:1998-08-01 00:00:00

  • Immediately loaded titanium implant with a tissue-stabilizing/maintaining design ('beyond platform switch') retrieved from man after 4 weeks: a histological and histomorphometrical evaluation. A case report.

    abstract:BACKGROUND:After implant insertion and loading, crestal bone usually undergoes remodeling and resorption. If the horizontal relationship between the outer edge of the implant and a smaller-diameter component ('platform switching') is altered, there seems to be reduced crestal bone loss. Immediate loading allows immedia...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2007.01449.x

    authors: Degidi M,Iezzi G,Scarano A,Piattelli A

    更新日期:2008-03-01 00:00:00

  • Long-term implant survival in the grafted maxilla: results of a 12-year retrospective study.

    abstract:OBJECTIVE:The aim of this study was to determine the long-term outcome of implant insertion in the augmented severely atrophied maxilla. STUDY DESIGN:Three hundred and twenty-four implants were inserted in 35 patients (eight males, 27 females, average age 57.6 years) in extremely atrophied maxillae after osteotomy and...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2004.01074.x

    authors: Yerit KC,Posch M,Hainich S,Turhani D,Klug C,Wanschitz F,Wagner A,Watzinger F,Ewers R

    更新日期:2004-12-01 00:00:00

  • Professional and patient-based evaluation of oral rehabilitation in patients with tooth agenesis.

    abstract:OBJECTIVES:The outcome of oral rehabilitation is usually monitored with clinical tests rather than by patient's perception of change. The aim of this study was to describe the objective measure and subjective perception of oral rehabilitation in patients with tooth agenesis. MATERIAL AND METHODS:The study included 129...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2008.01698.x

    authors: Dueled E,Gotfredsen K,Trab Damsgaard M,Hede B

    更新日期:2009-07-01 00:00:00

  • Immediate function on the day of surgery compared with a delayed implant loading process in the mandible: a randomized clinical trial over 5 years.

    abstract:OBJECTIVES:To appraise the feasibility of loading four implants with a pre-existing denture converted to a fixed dental prosthesis (FDP) on the day of implant surgery compared with waiting for 3- to 4-month healing. METHODS:Patients with an edentulous, fully healed mandible were recruited in a faculty clinic to partak...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/clr.12279

    authors: Jokstad A,Alkumru H

    更新日期:2014-12-01 00:00:00

  • Radiographic evaluation of marginal bone levels during healing period, adjacent to parallel-screw cylinder implants inserted in the posterior zone of the jaws, placed with flapless surgery.

    abstract:OBJECTIVE:The purpose of this study was to compare changes at the marginal bone level adjacent to implants placed with flapless surgery and flap surgery during a stress-free healing period. MATERIAL AND METHODS:Seven hundred and eighty-five implants were placed in 417 patients with a flapless approach and 459 implants...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2010.01961.x

    authors: Nickenig HJ,Wichmann M,Schlegel KA,Nkenke E,Eitner S

    更新日期:2010-12-01 00:00:00

  • Clinical outcomes of magnesium-incorporated oxidised implants: a randomised double-blind clinical trial.

    abstract:OBJECTIVES:This study evaluated implant stability and clinical outcomes obtained with magnesium-incorporated oxidised implants (Mg titanate) and compared them to those blasted magnesium-incorporated oxidised implants (blasted Mg titanate). PATIENTS AND METHODS:Mg titanate was manufactured using the microarc oxidation ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/clr.12091

    authors: Pang KM,Lee JW,Lee JY,Lee JB,Kim SM,Kim MJ,Lee JH

    更新日期:2014-05-01 00:00:00

  • Immediate placement and restoration of implants in the aesthetic zone with a trimodal approach: soft tissue alterations and its relation to gingival biotype.

    abstract:PURPOSE:The aim of this prospective study was to evaluate the soft tissue changes around implants in the aesthetic zone, placed under a trimodal approach (immediate post-extraction placement, flapless, and immediate provisional restoration) and its relationship to gingival/periodontal biotype of the patient. MATERIALS...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2012.02516.x

    authors: Cabello G,Rioboo M,Fábrega JG

    更新日期:2013-10-01 00:00:00

  • Proliferation, differentiation, and protein synthesis of human osteoblast-like cells (MG63) cultured on previously used titanium surfaces.

    abstract::This study compared osteoblasts proliferation, differentiation, and protein synthesis on new and used titanium (Ti) disks to test the hypothesis that cleaning and resterilization of previously used Ti disks does not alter cell response to a particular surface. Ti disks of varying roughness were prepared by one of five...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.1996.070104.x

    authors: Martin JY,Dean DD,Cochran DL,Simpson J,Boyan BD,Schwartz Z

    更新日期:1996-03-01 00:00:00

  • Comparison of three different preparations of platelet concentrates for growth factor enrichment.

    abstract::The aim of the present study was to compare three different systems for preparing platelet concentrates: two commercially available bed-side techniques (Curasan system and PCCS) and a procedure used routinely in transfusion medicine. Platelet concentrates were prepared from venous blood of 12 healthy male volunteers u...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.2002.130512.x

    authors: Appel TR,Pötzsch B,Müller J,von Lindern JJ,Bergé SJ,Reich RH

    更新日期:2002-10-01 00:00:00

  • Absorbable versus nonabsorbable membranes and bone grafts in the treatment of ligature-induced peri-implantitis defects in dogs. Part I. A clinical investigation.

    abstract::The purpose of this study was to clinically evaluate an absorbable collagen membrane (Bio-Gide) and a nonabsorbable polytetrafluoroethylene membrane (PTFE), associated or not with bone grafts, for the treatment of ligature-induced peri-implantitis defects in dogs. The bilateral mandibular premolars were removed from 5...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.2001.012002115.x

    authors: Nociti FH Jr,Machado MA,Stefani CM,Sallum EA,Sallum AW

    更新日期:2001-04-01 00:00:00

  • Peri-implant conditions and their relationship with periodontal conditions in Chinese patients: a cross-sectional study.

    abstract:OBJECTIVES:To analyze the relationships between peri-implant conditions and periodontal conditions in Chinese patients with dental implants in place for at least 1 year. MATERIAL AND METHODS:Seventy-six patients (mean age, 41 ± 10 years; range, 21-69 years) who received placement of 120 dental implants (Straumann(®) )...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12114

    authors: Wang R,Zhao W,Tang ZH,Jin LJ,Cao CF

    更新日期:2014-03-01 00:00:00

  • The influence of the masticatory mucosa on the peri-implant soft tissue condition.

    abstract::The aim of this study was to evaluate the soft tissue conditions at osseo-integrated oral implants in relation to the width of masticatory mucosa. Thirty-nine patients who had received a full-arch fixed bridge reconstruction > or = 10 years ago or a partial reconstruction > or = 5 years ago on a total of 171 implants ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.1994.050101.x

    authors: Wennström JL,Bengazi F,Lekholm U

    更新日期:1994-03-01 00:00:00

  • Quality and quantity of bone following alveolar distraction osteogenesis in the human mandible.

    abstract:PURPOSE:The purpose of this prospective study on humans were to evaluate (a) the clinical outcome of alveolar distraction osteogenesis for the correction of vertically deficient edentulous mandibular ridges, (b) the clinical outcome of dental implants placed in the distracted areas, and (c) the quality and quantity of ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2005.01247.x

    authors: Chiapasco M,Lang NP,Bosshardt DD

    更新日期:2006-08-01 00:00:00

  • Primary stability and self-tapping blades: biomechanical assessment of dental implants in medium-density bone.

    abstract:AIM:The aim of this biomechanical study was to assess the influence of self-tapping blades in terms of primary implant stability between implants with self-tapping blades and implants without self-tapping blades using five different analytic methods, especially in medium-density bone. MATERIALS AND METHODS:Two differe...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2010.02089.x

    authors: Kim YS,Lim YJ

    更新日期:2011-10-01 00:00:00

  • Enhanced implant integration with hierarchically structured implants: a pilot study in rabbits.

    abstract:AIM:To investigate bone-to-implant bonding for some novel surface modifications with a hierarchic structure and to correlate the in vivo results with surface roughness parameters. MATERIALS AND METHODS:Newly developed implants surfaces were tested in rabbits and compared with the commercially available OsseoSpeed™ (OS...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2011.02233.x

    authors: Johansson CB,Gretzer C,Jimbo R,Mattisson I,Ahlberg E

    更新日期:2012-08-01 00:00:00

  • Guided bone regeneration around non-submerged implants in narrow alveolar ridges: a prospective long-term clinical study.

    abstract:OBJECTIVES:This prospective clinical study investigates long-term survival and clinical parameters of non-submerged implants with large buccal dehiscences treated with a deproteinized bovine bone mineral xenograft and a non-resorbable membrane in a one-stage approach. MATERIAL AND METHODS:Sixteen consecutive non-subme...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2005.01154.x

    authors: De Boever AL,De Boever JA

    更新日期:2005-10-01 00:00:00

  • Retraction.

    abstract::Ramírez-Fernández MP, Calvo-Guirado JL, Arcesio Delgado-Ruiz R, Maté-Sánchez del Val JE, Gómez-Moreno G, Guardia J. Experimental model of bone response to xenografts of bovine origin (Endobon® ): a radiological and histomorphometric study. Clin Oral Impl Res. 2011;22: 727-734. The above article, published online on 29...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章,撤回出版物

    doi:10.1111/clr.13085

    authors:

    更新日期:2018-06-01 00:00:00

  • The antibiotic of choice determined by antibiogram in maxillary sinus elevation surgery: a clinical study.

    abstract:OBJECTIVES:This study set out to make antibiograms of positive bacteria cultures in samples collected when performing maxillary sinus elevations to determine a specific and effective antibiotic in each case. MATERIAL AND METHODS:A total of 174 patients (90 women and 84 men) with a mean age of 55.92 years underwent 227...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.12835

    authors: Carreño Carreño J,Gómez-Moreno G,Aguilar-Salvatierra A,Martínez Corriá R,Menéndez López-Mateos ML,Menéndez-Núñez M

    更新日期:2018-11-01 00:00:00

  • Simultaneous dental implant placement and endoscope-guided internal sinus floor elevation: 2-year post-loading outcomes.

    abstract:AIMS:To determine whether endoscope-guided sinus elevation procedures can be consistently used to create sufficient bone support for stable implant placement and long-term implant success. MATERIAL AND METHODS:Sixty-two implants were surgically placed into 30 patients (14 men and 16 women) following internal sinus ele...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2008.01561.x

    authors: Schleier P,Bierfreund G,Schultze-Mosgau S,Moldenhauer F,Küpper H,Freilich M

    更新日期:2008-11-01 00:00:00

  • The effect of SLActive surface in guided bone formation in osteoporotic-like conditions.

    abstract:OBJECTIVES:The aim of the study was to evaluate new bone formation under etched titanium (SLA) and modified-etched hydrophilic titanium (modSLA) domes placed on the calvarium of healthy, osteoporotic and osteoporotic treated with bisphosphonates rabbits. METHODS:Experimental osteoporosis was induced by ovariectomy (OV...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0501.2010.02094.x

    authors: Mardas N,Schwarz F,Petrie A,Hakimi AR,Donos N

    更新日期:2011-04-01 00:00:00

  • Trends in the level of evidence and impact of clinical studies published in leading oral implantology journals: 2008-2018.

    abstract:OBJECTIVES:To present the characteristics and level of evidence (LOE) of clinical studies published in leading oral implantology journals during 2008-2018 and to explore whether the LOE of a study is associated with its scientific and social impact. MATERIALS AND METHODS:Clinical studies with direct relevance to the e...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1111/clr.13641

    authors: Wu X,Hu Q,Yan Q,Zhang T,Riley P,Hua F,Shi B,Tu YK

    更新日期:2020-10-01 00:00:00

  • Posterior jaw bone resorption in osseointegrated implant-supported overdentures.

    abstract::For several years, osseointegrated implant-supported overdentures have been used in the rehabilitation of full edentulism with excellent results, at least in the lower jaw. This study involved 3 groups of patients with different prosthetic reconstructions: (1) mandibular overdentures supported by 2 implants connected ...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.1992.030203.x

    authors: Jacobs R,Schotte A,van Steenberghe D,Quirynen M,Naert I

    更新日期:1992-06-01 00:00:00

  • Implant-supported fixed cantilever prostheses in partially edentulous arches. A seven-year prospective study.

    abstract::The purpose of the following study was to evaluate the medium- to long-term prognosis of implant-supported cantilever fixed prostheses, and to establish to what degree this is influenced by factors such as length, type of cantilever (mesial or distal), and opposite dentition versus cantilever prostheses. This study wa...

    journal_title:Clinical oral implants research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0501.2003.120905.x

    authors: Romeo E,Lops D,Margutti E,Ghisolfi M,Chiapasco M,Vogel G

    更新日期:2003-06-01 00:00:00