Abstract:
OBJECTIVE:To determine the prevalence of hyperhomocystinemia in patients with acute ischemic syndrome of the unstable angina type. METHODS:We prospectively studied 46 patients (24 females) with unstable angina and 46 control patients (19 males), paired by sex and age, blinded to the laboratory data. Details of diets, smoking habits, medication used, body mass index, and the presence of hypertension and diabetes were recorded, as were plasma lipid and glucose levels, C-reactive protein, and lipoperoxidation in all participants. Patients with renal disease were excluded. Plasma homocysteine was estimated using high-pressure liquid chromatography. RESULTS:Plasma homocysteine levels were significantly higher in the group of patients with unstable angina (12.7+/-6.7 micromol/L) than in the control group (8.7+/-4.4 micromol/L) (p<0.05). Among males, homocystinemia was higher in the group with unstable angina than in the control group, but this difference was not statistically significant (14.1+/-5.9 micromol/L versus 11.9+/-4.2 micromol/L). Among females, however, a statistically significant difference was observed between the 2 groups: 11.0+/-7.4 micromol/L versus 6.4+/-2.9 micromol/L (p<0.05) in the unstable angina and control groups, respectively. Approximately 24% of the patients had unstable angina at homocysteine levels above 15 micromol/L. CONCLUSION:High homocysteine levels seem to be a relevant prevalent factor in the population with unstable angina, particularly among females.
journal_name
Arq Bras Cardioljournal_title
Arquivos brasileiros de cardiologiaauthors
Tavares JR,D'Almeida V,Diniz DC,Terzi CA,Cruz EN,Stefanini E,Andriollo A,Paola AA,Carvalho ACdoi
10.1590/s0066-782x2002001100008subject
Has Abstractpub_date
2002-08-01 00:00:00pages
161-72issue
2eissn
0066-782Xissn
1678-4170pii
S0066-782X2002001100008journal_volume
79pub_type
临床试验,杂志文章abstract:BACKGROUND:There have been few studies on cardiovascular risk factors in adolescents with different degrees of obesity. OBJECTIVE:To evaluate metabolic effects associated with different degrees of obesity in adolescents and their impact on cardiovascular risks. METHODS:Cross-sectional study of 80 obese adolescents, d...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2010005000166
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2012005000048
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abstract:BACKGROUND:Although thrombolysis and primary CTA are well-established procedures, they are not administered in a large proportion of the patients with STEMI who arrive to the emergency rooms. OBJECTIVE:Describe initial and final the results in a cohort of STEMI patients METHODS:The study included, from hospital admis...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2009000600009
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
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journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2010005000162
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abstract:BACKGROUND:There is evidence that prehospital thrombolysis improves the outcome in ST-elevation myocardial infarction (STEMI). OBJECTIVE:This study aimed at comparing the cost-effectiveness of prehospital compared to inhospital thrombolysis for STEMI from the National Health System perspective. METHODS:A decision-ana...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
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journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 临床试验,杂志文章
doi:
更新日期:1994-07-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2005001800007
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journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章,meta分析,评审
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更新日期:2010-07-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x1998000100002
更新日期:1998-01-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2003000900002
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章,meta分析,评审
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:
更新日期:1996-02-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1590/s0066-782x2012005000104
更新日期:2012-12-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
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更新日期:2016-10-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.5935/abc.20140050
更新日期:2014-05-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2008000500006
更新日期:2008-05-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2005000400003
更新日期:2005-04-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-07-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:
更新日期:1997-06-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
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更新日期:2009-09-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x1999001200004
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