Abstract：
:The only antimalarial drug approved by the Food and Drug Administration for the treatment of lupus erythematosus is hydroxychloroquine (Plaquenil) sulfate. The dosage recommended officially for this disease is vague. Retinopathy has been caused by hydroxychloroquine but not in less than six months, nor when a total dosage of less than 72 gm or a daily dose of 200 mg or less is used. The ocular risk depends on the dose/weight ratio and is almost negligible at a dosage of less than 6 mg/kg/day. At a dosage of 400 mg or more daily, the risk/benefit ratio is acceptable for a person of average weight, provided that ophthalmologic monitoring is adequate. Risk of retinal toxicity is then proportional to duration of therapy and consequent cumulative dose. Ophthalmoscopic examinations at six-month intervals should be sufficient to detect occasional adverse reactions. Such tests could be conducted by the attending physician directly, as long as no pre-existing ocular abnormality exists.
journal_name
Cutisjournal_title
Cutisauthors
Potter Bsubject
Has Abstractpub_date
1993-10-01 00:00:00pages
229-31issue
4eissn
0011-4162issn
2326-6929journal_volume
52pub_type
杂志文章相关文献
CUTIS文献大全abstract：:A black patient with an enlarging apocrine cystadenoma on the chest is presented herein. This location is very infrequent for this benign lesion. This is the second report of an apocrine cystadenoma in a black person. ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1979-03-01 00:00:00
abstract：:Pseudofolliculitis barbae (PFB) is an inflammatory disorder characterized by the formation of papules, pustules, and hyperpigmentation as a result of ingrown hairs. It is estimated that PFB affects 45% to 83% of black men who shave regularly. In this multicenter, double-blind pilot study, men with 16 to 100 combined p...
journal_title：Cutis
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2004-06-01 00:00:00
abstract：:There is more than one reason why dermatologists should listen to their patients. Audible signs of cutaneous disease range from the classic, early childhood hoarseness of lipoid proteinosis to a characteristic hoarseness due to syphilitic papules on the epiglottis and arytenoepiglottic folds. ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1983-02-01 00:00:00
abstract：:The scar resulting from elective cutaneous surgery can be minimized if the location of the incision is chosen after considering the direction of the skin tension lines, creases, and wrinkles, and if the patient is positioned so that the skin of the surgical field is in a relaxed or anatomically neutral position. Selec...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1976-11-01 00:00:00
abstract：:We describe the case of a 38-year-old epileptic man with tufted hair folliculitis. The condition started 5 years ago after a scalp laceration that had been sustained 3 months earlier during an epileptic crisis. There then appeared a circumscribed inflammatory bulging lesion (with exudation and crusts) that evolved to ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2001-03-01 00:00:00
abstract：:Reactive perforating collagenosis (RPC) is a rare disorder characterized by transepidermal elimination of altered collagen. The acquired form of RPC manifests in adult life and is accompanied by general pruritus and scratching. Diabetes mellitus and end-stage renal disease are frequently associated with RPC. We descri...
journal_title：Cutis
pub_type： 杂志文章,评审
doi：
更新日期：2000-12-01 00:00:00
abstract：:We report the case of a 64-year-old man with androgenetic alopecia who was started on methotrexate therapy for treatment of psoriasis after traditional modalities failed. Following treatment with methotrexate, he noted hair regrowth on the scalp. We propose that methotrexate may inhibit gonadal steroidogenesis, theref...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2013-09-01 00:00:00
abstract：:Cutaneous B-cell lymphomas represent a group of lymphomas derived from B lymphocytes in various stages of differentiation. The skin can be the site of primary or secondary involvement of any of the B-cell lymphomas. The classification of primary cutaneous B-cell lymphomas has evolved as the use of immunohistochemical ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2018-12-01 00:00:00
abstract：:Polymethylmethacrylate (PMMA) is a synthetic polymer with multiple uses in industry and medicine. In dermatology, it is primarily used as an injectable implant for the correction of rhytides. We report the first case of an adverse event caused by the recreational use of PMMA in the form of an invisible tattoo granulom...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2008-03-01 00:00:00
abstract：:This report describes a high school football player with an unusual ulcerative lesion on the upper leg that was treated initially as pyoderma gangrenosum, but later proved to be due to Sporothrix schenckii. His treatment with potassium iodide solution was complicated by the occurrence of subclinical hypothyroidism. ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:We describe a patient with localized chronic fibrosing vasculitis who presented with a rhinophymalike eruption of the nose. To our knowledge, the manifestation of this condition on the nose has not been previously reported. The differential diagnosis also is examined. ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2006-11-01 00:00:00
abstract：:Cutaneous angiosarcoma is a rare aggressive malignancy of vascular origin that usually arises in the scalp or face of elderly men. We describe a case of primary cutaneous angiosarcoma with skin metastases and presumed metastases to the lung in a 58-year-old man who presented with persistent bloody pleural effusions, a...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2012-03-01 00:00:00
abstract：:Skin cancer is the most common form of cancer in the United States, with more than 1 million cases of nonmelanoma skin cancer diagnosed annually and an estimated 53,600 cases of melanoma and 7400 deaths expected during the year 2002. Excess exposure to UV radiation has long been linked to both melanoma and nonmelanoma...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2003-05-01 00:00:00
abstract：:Nevus sebaceus (NS) is a congenital skin lesion arising on the face and scalp that has been linked to the development of various carcinomas. We describe a case of microcystic adnexal carcinoma (MAC) arising in an NS on the scalp of a 62-year-old man. Excisional skin biopsy and hematoxylin and eosin stains were perform...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2007-10-01 00:00:00
abstract：:Basal cell carcinomas (BCCs) and cutaneous squamous cell carcinomas (SCCs) are the most common malignancies in humans. Together, they constitute approximately 95% of nonmelanoma skin cancers (NMSCs). Surgical excision remains the mainstay of therapy of low-risk NMSC, though Mohs micrographic surgery is the gold standa...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2007-03-01 00:00:00
abstract：:A new approach to the diagnosis and measurement of the thickness of basal cell epithelioma (BCE) by ultrasonography is described. The advantages and efficacy of the new technique are presented. ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1984-11-01 00:00:00
abstract：:A 37-year-old woman was examined for a large, dark brown plaque on her left hip that had been present for three years and a second, similar plaque that had subsequently appeared on her right knee. Every four to five months the areas became swollen, red, and painful. She had been taking metronidazole intermittently for...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1987-05-01 00:00:00
abstract：:An otherwise asymptomatic woman presented with the recent onset of telangiectasias of the lips and fingertips, and without a family history of similar lesions. Results of laboratory tests included elevated liver function, positive antimitochondrial antibodies, and microscopic findings compatible with the diagnosis of ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1985-02-01 00:00:00
abstract：:Verruciform xanthoma is a benign disorder affecting skin and mucosa. Although most cases have been reported to occur in the mouth, other sites may be affected, most notably the genitalia. A large, exophytic verruciform xanthoma involving the glans penis is reported. The clinical similarity to a malignancy, especially ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1993-05-01 00:00:00
abstract：:Tissue expansion in dermatologic surgery has gained wide acceptance. We report the case of a patient with basal cell carcinoma in whom a Foley catheter was used for immediate intraoperative tissue expansion. Wound tension was decreased significantly and primary closure obtained. This technique is appropriate for offic...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：:Erythrodermic mastocytosis is a rare variant of diffuse cutaneous mastocytosis in which the skin becomes red, thickened, and lichenified and has a doughy consistency with multiple small papules on its surface, giving a leathery appearance to the skin. In this report, I describe a curious case of erythrodermic mastocyt...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1992-03-01 00:00:00
abstract：:A 70-year-old woman presented for evaluation of symmetric necrotic ulcers of the lower extremities. Biopsy results revealed changes consistent with calciphylaxis. The predisposing factors in this patient included calcium supplementation, obesity, female gender, viscous blood, renal failure, and diabetes mellitus. To o...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2005-06-01 00:00:00
abstract：:The topical antifungal agent naftifine has shown considerable potency against a broad spectrum of dermatophytes. In this study, an in vitro penetration test in human cadaver skin and an in vivo tape-stripping test were used to evaluate the penetration and antifungal activity of naftifine gel 1 percent and naftifine cr...
journal_title：Cutis
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1989-10-01 00:00:00
abstract：:Predisposition to cutaneous viral infections is known to be a minor criterion of Hanifin and Rajka's diagnostic standard of atopic dermatitis (AD); however, the causal relationship between molluscum contagiosum virus (MCV) infection and AD onset or aggravation has not been widely explored. The objective of this study ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2018-09-01 00:00:00
abstract：:We report a case of contact sensitivity to a cycloplegic mydriatic agent (Mydrin-P) on the fingers of a nurse whose work included the instillation of eyedrops into patients undergoing routine funduscopic examination in a hospital ophthalmology department. The lesion showed well-demarcated brownish erythema with scalin...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1991-05-01 00:00:00
abstract：:Merkel cell carcinoma (MCC), also termed cutaneous small cell carcinoma or trabecular carcinoma, is a rare tumor that most often presents as a solitary nodule on the head, neck, or extremities of older adults. It is an aggressive tumor that usually is fatal due to rapid metastasis. Involvement of lymph nodes at presen...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
abstract：:Six patients with perioral dermatitis were successfully treated with a combination of 1.5 percent erythromycin topical solution twice a day and topically applied hydrocortisone valerate cream. Application of erythromycin solution seems to be an effective topical therapy. Hydrocortisone valerate cream, when used in a c...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1983-06-01 00:00:00
abstract：:Henoch-Schönlein purpura (HSP) is the most common cause of nonthrombocytopenic purpura in children. The clinical picture is classically a cutaneous purpuric eruption of the legs and buttocks and infrequently the upper torso and extremities. Arthritis, gastrointestinal tract symptoms, and nephritis are other common fin...
journal_title：Cutis
pub_type： 杂志文章,评审
doi：
更新日期：2006-02-01 00:00:00
abstract：:Basal cell carcinoma (BCC) is the most common malignancy worldwide and is characterized by invasive growth and local tissue destruction. Cure rates for BCC exceed 90% with most treatment modalities. Metastasizing BCC (MBCC) is a rare complication of BCC with high morbidity and mortality rates. We report the case of a ...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：2013-11-01 00:00:00
abstract：:Multinucleate cell angiohistiocytoma (MCA) is a benign fibrohistiocytic vascular tumor affecting predominantly the acral sites in elderly women. The disorder is often confused clinically and histologically with Kaposi's sarcoma. We report the case of a 63-year-old woman with MCA and describe the main clinical and hist...
journal_title：Cutis
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
