Prognostic significance of rises in parasitaemia during treatment of falciparum malaria.

Abstract:

:Transient rises in parasitaemia occur commonly during the treatment of falciparum malaria but their prognostic significance has not been well defined. Twelve-hourly parasite counts from 133 malaria patients who were ultimately cured were therefore compared with counts from 97 therapeutic failures to determine if increase in parasitaemia was a useful early indicator of poor treatment response. Parasitaemia in both groups frequently rose during the initial 12 h of therapy (41% of all patients), but rising counts thereafter were rarer in treatment successes (P < 0.01). The relative risk of treatment failure was 3.8 if the count was higher at 24 h than 12 h, rose to 7.8 for increases at 48-60 h, and was 13.7 and 19.4 for counts above admission levels at 48 h and 60 h. These data suggest a way to identify patients at high risk of treatment failure.

authors

Watt G,Shanks GD,Phintuyothin P

doi

10.1016/0035-9203(92)90217-z

subject

Has Abstract

pub_date

1992-07-01 00:00:00

pages

359-60

issue

4

eissn

0035-9203

issn

1878-3503

journal_volume

86

pub_type

杂志文章
  • Dynamics of malaria parasitaemia associated with febrile illness in children from a rural area of Madang, Papua New Guinea.

    abstract::Active community and self-reporting surveillance techniques have been used to describe the dynamics of febrile illness and associated malaria infection in children aged 2 to 15 years from a rural area of Madang Province, Papua New Guinea (PNG). Both history of fever and fever in association with parasitaemia appeared ...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(94)90292-5

    authors: Cox MJ,Kum DE,Tavul L,Narara A,Raiko A,Baisor M,Alpers MP,Medley GF,Day KP

    更新日期:1994-03-01 00:00:00

  • Malaria chemoprophylaxis, birth weight and child survival.

    abstract::Study of the effects of malaria chemoprophylaxis given during pregnancy on birthweight and investigation of the influence of birthweight on child survival suggest that, in a rural area of The Gambia, chemoprophylaxis given during pregnancy might reduce infant mortality by about one-fifth in the children of primigravid...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0035-9203(92)90078-q

    authors: Greenwood AM,Armstrong JR,Byass P,Snow RW,Greenwood BM

    更新日期:1992-09-01 00:00:00

  • Onchocerciasis in Sierra Leone. I. Studies on the prevalence and transmission at Gbaiima village.

    abstract::A longitudinal survey--parasitological, clinical, immunological and entomological--of onchocerciasis is being conducted in Gbaiima village in Sierra Leone. The estimated Annual Transmission Potential (ATP) is 5863. More than 80% of the annual transmission occurs between October and December. Four species of the Simuli...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(86)90389-5

    authors: McMahon JE,Davies JB,White MD,Goddard JM,Beech-Garwood PA,Kirkwood BR

    更新日期:1986-01-01 00:00:00

  • Strongyloides stercoralis septicaemia following steroid therapy for eosinophilia: report of three cases.

    abstract::Three apparently immunocompetent patients died in the intensive care unit at Loni Hospital, Ahmednagar, Maharashtra, India, between 2001 and 2006 due to multiorgan failure and Strongyloides stercoralis septicaemia following a short course of corticosteroid (prednisolone) therapy of 6-17 days for peripheral blood eosin...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2007.05.021

    authors: Ghosh K,Ghosh K

    更新日期:2007-11-01 00:00:00

  • Immune response in a symptomatic case of Tetrapetalonema perstans infection.

    abstract::The immune response in a 49-year-old Italian nun affected by Tetrapetalomena (Dipetalonema) perstans following an eight-year stay in Cameroon is reported. On admission the patient presented with polyarthralgia, conjunctival pruritus and irritation, oedema of the limbs, generalized itching, hypereosinophilia and low to...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(84)90069-5

    authors: Almaviva M,Galli M,Rizzi M,Simonelli E,Negri C,Vigevani GM

    更新日期:1984-01-01 00:00:00

  • Indoor air pollution from biomass fuel smoke is a major health concern in the developing world.

    abstract::One-third of the world's population burn organic material such as wood, dung or charcoal (biomass fuel) for cooking, heating and lighting. This form of energy usage is associated with high levels of indoor air pollution and an increase in the incidence of respiratory infections, including pneumonia, tuberculosis and c...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章,评审

    doi:10.1016/j.trstmh.2008.05.028

    authors: Fullerton DG,Bruce N,Gordon SB

    更新日期:2008-09-01 00:00:00

  • A high prevalence of HIV-1 infection among pregnant women living in a rural district of north Uganda severely affected by civil strife.

    abstract::This study aims at estimating the recent trends in HIV-1 prevalence and the factors associated with infection among pregnant women in the Gulu District of north Uganda, a rural area severely affected by civil strife. In 2000-2003, a total of 4459 antenatal clinic attendees of Lacor Hospital were anonymously tested for...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2005.09.002

    authors: Fabiani M,Nattabi B,Opio AA,Musinguzi J,Biryahwaho B,Ayella EO,Ogwang M,Declich S

    更新日期:2006-06-01 00:00:00

  • Fundamental issues in mosquito surveillance for arboviral transmission.

    abstract::Marked spatiotemporal variabilities in mosquito infection of arboviruses, exemplified by the transmission of West Nile virus (WNV) in America, require adaptive strategies for mosquito sampling, pool screening and data analyses. Currently there is a lack of reliable and consistent measures of risk exposure, which may c...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2008.03.019

    authors: Gu W,Unnasch TR,Katholi CR,Lampman R,Novak RJ

    更新日期:2008-08-01 00:00:00

  • Seroepidemiological study of Helicobacter pylori infection in South African children.

    abstract::The seroepidemiology of Helicobacter pylori infection was studied in 681 randomly selected Black children from newborn to 13 years of age (333 boys, mean age 8.05 years, and 348 girls, mean age 7.76 years) in KwaZulu/Natal, South Africa. H. pylori infection was identified serologically using an enzyme-linked immunosor...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/s0035-9203(97)90253-4

    authors: Sathar MA,Gouws E,Simjee AE,Mayat AM

    更新日期:1997-07-01 00:00:00

  • Virological surveillance for early warning of dengue epidemics in the State of Rio de Janeiro, Brazil.

    abstract:BACKGROUND:The state of Rio de Janeiro has been important since 1986 as a portal for the introduction of dengue virus (DENV) into Brazil and dissemination of the virus throughout the country. This study describes an active surveillance of DENV in the state of Rio de Janeiro from 2004 to 2008. METHOD:A total of 14 408 ...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1093/trstmh/trs091

    authors: Macedo GA,de Araújo JM,Schatzmayr HG,Costa FA,de Filippis AM,Santos FB,Nogueira RM

    更新日期:2013-03-01 00:00:00

  • Strongyloidiasis in a high risk community of Dhaka, Bangladesh.

    abstract::Residents of a slum community of Dhaka city, Bangladesh were tested by serological and faecal examination for evidence of Strongyloides stercoralis infection. In stool specimens from a total of 147 participants Strongyloides larvae were found in 34 (23.1%) by Harada-Mori culture, 15 (10.2%) by agar plate culture (APC)...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2012.08.011

    authors: Sultana Y,Gilbert GL,Ahmed BN,Lee R

    更新日期:2012-12-01 00:00:00

  • Genetic structure and dynamics of Plasmodium falciparum infections in the Kilombero region of Tanzania.

    abstract::Plasmodium falciparum parasites exist as genetically distinct haploid clones in infected people. In the Kilombero valley in south-east Tanzania, at least 85% of the inhabitants of Michenga village harbour more than one clone. Using 2 highly polymorphic unlinked markers, it has been estimated that each infected person ...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章,评审

    doi:10.1016/s0035-9203(99)90321-8

    authors: Babiker HA,Ranford-Cartwright LC,Walliker D

    更新日期:1999-02-01 00:00:00

  • Oliva vidua fulminans, a marine mollusc, responsible for five fatal cases of neurotoxic food poisoning in Sabah, Malaysia.

    abstract::This is the first report in which a marine mollusc, Oliva vidua fulminans (olives), generally not known to be poisonous, was responsible for death in five children after consuming boiled olives with tamarind. The onset of symptoms was rapid 10 to 20 min after consumption of the olives. Signs and symptoms included naus...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(86)90197-5

    authors: Kan SK,Singh N,Chan MK

    更新日期:1986-01-01 00:00:00

  • Molecular mechanisms associated with quinolone resistance in Enterobacteriaceae: review and update.

    abstract:BACKGROUND:Quinolones are broad-spectrum antibiotics, which are used for the treatment of different infectious diseases associated with Enterobacteriaceae. During recent decades, the wide use as well as overuse of quinolones against diverse infections has led to the emergence of quinolone-resistant bacterial strains. H...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1093/trstmh/traa041

    authors: Azargun R,Gholizadeh P,Sadeghi V,Hosainzadegan H,Tarhriz V,Memar MY,Pormohammad A,Eyvazi S

    更新日期:2020-10-05 00:00:00

  • Antimicrobial susceptibility test of Helicobacter pylori isolated from Jos, Nigeria.

    abstract::Fifty-five strains of Helicobacter pylori isolated from November 1997 until October 1998 from 33 female and 22 male adults attending for endoscopy at the Evangel Hospital, Jos, Nigeria were assayed for antibiotic susceptibility to amoxycillin, clarithromycin, metronidazole and tetracycline by the E-test strip method. ...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/s0035-9203(99)90089-5

    authors: Ani AE,Malu AO,Onah JA,Queiroz DM,Kirschner G,Rocha GA

    更新日期:1999-11-01 00:00:00

  • Skin diseases of children in Mali: a public health problem.

    abstract::In order to estimate the importance as a public health problem of skin diseases, we investigated the prevalence and severity of skin diseases in a representative sample of children in Mali. 1817 children were randomly selected in 30 clusters by probability-proportional-to-size sampling in Koulikoro region. The mean pr...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(95)90068-3

    authors: Mahé A,Prual A,Konaté M,Bobin P

    更新日期:1995-09-01 00:00:00

  • Sensitivity of Trichomonas vaginalis, Tritrichomonas foetus and Giardia intestinalis to bacitracin and its zinc salt in vitro.

    abstract::The activity of bacitracin in vitro against Giardia intestinalis, Trichomonas vaginalis and Tritrichomonas foetus was enhanced 5-10 times by equimolar concentrations of zinc. Bacitracin and bacitracin zinc activity was tolerant to either aerobic or anaerobic culture conditions and equally effective against T. vaginali...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(94)90239-9

    authors: Andrews BJ,Mylvaganam H,Yule A

    更新日期:1994-11-01 00:00:00

  • Neurocysticercosis in patients with active epilepsy from the pig farming community of Lucknow district, north India.

    abstract::Epilepsy is a major health problem worldwide, and neurocysticercosis (NCC) is one of the important causes of epilepsy in the tropics. The present study was carried out in a rural pig farming community of north India to estimate the prevalence of NCC in patients with active epilepsy (AE) and to determine the associated...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.trstmh.2008.07.015

    authors: Prasad KN,Prasad A,Gupta RK,Nath K,Pradhan S,Tripathi M,Pandey CM

    更新日期:2009-02-01 00:00:00

  • Urinary NAG as an early indicator of renal damage in Russell's viper bite envenomation.

    abstract::Urinary N-acetyl-beta-D-glucosaminidase (NAG; beta-N-acetylglucosaminidase; EC 3.2.1.30), blood urea, serum creatinine and creatinine clearance were measured in 23 patients bitten by Russell's viper (Daboia russelii siamensis), with systemic envenomation, at different time intervals after the bite during clinical obse...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/s0035-9203(96)90125-x

    authors: Win-Aung,Aye-Kyaw,Tin-Win,San-Kun,Thin-Thin-Hlaing

    更新日期:1996-03-01 00:00:00

  • Haptoglobin genotypes are not associated with resistance to severe malaria in The Gambia.

    abstract::The influence of haptoglobin polymorphisms on severe malaria occurrence was assessed in 1183 individuals from The Gambia. No significant association was found between severe malaria and either haptoglobin genotypes or phenotypes. The advantages of using a deoxyribonucleic acid-based haptoglobin typing method are discu...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/s0035-9203(02)90114-8

    authors: Aucan C,Walley AJ,Greenwood BM,Hill AV

    更新日期:2002-05-01 00:00:00

  • Serum alpha-feto protein (alpha-FP) and hepatoma in Rhodesian Africans.

    abstract::Alpha-feto protein (alpha-FP) is now accepted as a very useful serum marker of hepatocarcinoma, and since its discovery in 1963, surveys have been carried out in various regions of the world, where hepatoma is particularly prevalent, which have shown that alpha-FP may be detected in 50 to 80% of patients with liver ca...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(75)90157-1

    authors: Seggie J,Gelfand M

    更新日期:1975-01-01 00:00:00

  • The role of reduced red cell deformability in the pathogenesis of severe falciparum malaria and its restoration by blood transfusion.

    abstract::As reduced red cell deformability (RCD) can contribute to derangement of the microcirculation, a central feature in the pathogenesis of severe malaria, RCD was measured with a laser diffraction technique in 232 consecutive patients with falciparum malaria on the Kenyan coast, of whom 99 had severe disease. RCD on admi...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/s0035-9203(02)90100-8

    authors: Dondorp AM,Nyanoti M,Kager PA,Mithwani S,Vreeken J,Marsh K

    更新日期:2002-05-01 00:00:00

  • Canine and rodent leishmanial isolates from Egypt.

    abstract::Two leishmanial stocks isolated in Egypt, one from a dog and the other from Rattus norvegicus, were typed according to their excreted factor (EF) serotype and the electrophoretic mobility of their glucose phosphate isomerase. The canine isolate was indistinguishable from L. donovani (= L. infantum ) strains. The rat i...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(84)90295-5

    authors: Azab ME,Rifaat MA,Schnur LF,Makhlouf SA,El-Sherif E,Salem AM

    更新日期:1984-01-01 00:00:00

  • Artemether administered together with haemin damages schistosomes in vitro.

    abstract::We conducted experiments in vitro to assess the effect of artemether in combination with haemin on adult Schistosoma japonicum, S. mansoni and S. haematobium. When schistosomes were maintained in a medium containing artemether at concentrations of 20 micrograms/mL or less for 72 h, no apparent effect on the schistosom...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/s0035-9203(01)90336-0

    authors: Xiao S,Chollet J,Utzinger J,Matile H,Mei J,Tanner M

    更新日期:2001-01-01 00:00:00

  • Efficacy of artemether-lumefantrine versus dihydroartemisinin-piperaquine for the treatment of uncomplicated malaria among children in Rwanda: an open-label, randomized controlled trial.

    abstract:BACKGROUND:Artemisinin-based combination therapies (ACTs) have proven highly effective in reducing malaria morbidity in sub-Saharan Africa. Artemether-lumefantrine (AL) was introduced in 2005 as a first-line ACT for the treatment of uncomplicated malaria in Rwanda. Monitoring the therapeutic efficacy of ACTs is necessa...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/trstmh/trz009

    authors: Uwimana A,Penkunas MJ,Nisingizwe MP,Warsame M,Umulisa N,Uyizeye D,Musanabaganwa C,Munyaneza T,Ntagwabira E,Hakizimana D,Muvunyi CM,Kayobotsi C,Kabera M,Murindahabi M,Mbituyumuremyi A

    更新日期:2019-06-01 00:00:00

  • Prevalence of tuberculosis in TB suspects with short duration of cough.

    abstract::The prevalence of pulmonary tuberculosis (PTB) in patients with short duration of cough was determined. Ninety-eight adult out-patients (60 men, 38 women; mean age 32 years) at Queen Elizabeth Central Hospital, Blantyre, Malawi, who had cough for 1-3 weeks which was unresponsive to a course of antibiotics, were succes...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/s0035-9203(98)90727-1

    authors: Banda HT,Harries AD,Welby S,Boeree MJ,Wirima JJ,Subramanyam VR,Maher D,Nunn PA

    更新日期:1998-03-01 00:00:00

  • A comparison of skin-test responses using antigen from Leishmania donovani and a lizard trypanosome.

    abstract::261 individuals were skin tested with leishmanin from Leishmania donovani and with an antigen from a lizard trypanosome isolated in an area endemic for kala-azar in Ethiopia. 83 of the 261 responded positively, with indurations of 5 mm or greater, to one antigen but negatively to the other, and 42 reacted positively t...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(80)90247-3

    authors: Fuller GK,Lemma A,Haile T

    更新日期:1980-01-01 00:00:00

  • Blood pressure patterns in relation to age, weight and urinary electrolytes in three Kenyan communities.

    abstract::The blood pressure patterns of three Kenyan communities have been studied: 861 members of the Luo tribe in a rural community, 281 members of the Kamba tribe in a rural community and 310 "urban" Luo living in Nairobi. The slope of linear regression of blood pressure with age was significantly different in each populati...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/0035-9203(85)90390-6

    authors: Poulter NR,Khaw KT,Mugambi M,Peart WS,Rose G,Sever P

    更新日期:1985-01-01 00:00:00

  • Toxoplasmic meningoencephalitis in an immunocompetent host.

    abstract::Central nervous system involvement due to toxoplasmosis in an immunocompetent host is very rare. We report a case of an immunocompetent patient who presented with suspected tuberculous meningoencephalitis but showed no clinical response to antitubercular therapy. Later, toxoplasmic meningoencephalitis was proved by po...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2005.06.017

    authors: Kaushik RM,Mahajan SK,Sharma A,Kaushik R,Kukreti R

    更新日期:2005-11-01 00:00:00

  • Reaction time in patients with HIV/AIDS and correlation with CD4 count: a case-control study.

    abstract::There are conflicting reports on the presence of neurocognitive dysfunction during the initial, medically asymptomatic stage of HIV infection. This study aimed to assess the psychomotor speed and attention ability of antiretroviral treatment-naïve Nigerian Africans with HIV/AIDS and the impact of CD4 levels on their c...

    journal_title:Transactions of the Royal Society of Tropical Medicine and Hygiene

    pub_type: 杂志文章

    doi:10.1016/j.trstmh.2006.10.002

    authors: Ogunrin AO,Odiase FE,Ogunniyi A

    更新日期:2007-05-01 00:00:00