Selective serotonin reuptake inhibitor-induced rhabdomyolysis associated with irinotecan.

Abstract:

:A 74-year-old man was admitted with rhabdomyolysis after undergoing initial treatment for gastrointestinal cancer with irinotecan. The syndrome partially resolved after the discontinuation of all of his usual medications, including his chronic selective serotonin reuptake inhibitor (SSRI). The rhabdomyolysis was exacerbated upon reinitiation of the SSRI and disappeared when the SSRI was discontinued. The combination of irinotecan and SSRI resulted in potentially lethal rhabdomyolysis.

journal_name

South Med J

journal_title

Southern medical journal

authors

Richards S,Umbreit JN,Fanucchi MP,Giblin J,Khuri F

doi

10.1097/01.SMJ.0000084311.35864.D6

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

1031-3

issue

10

eissn

0038-4348

issn

1541-8243

journal_volume

96

pub_type

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