Safety and efficacy of convection-enhanced delivery of gemcitabine or carboplatin in a malignant glioma model in rats.

abstract：:Surgical treatments for moyamoya disease (MMD) include direct revascularization procedures with proven efficacy, for example, superficial temporal artery (STA) to middle cerebral artery (MCA) bypass, STA to anterior cerebral artery bypass, occipital artery (OA) to MCA bypass, or OA to posterior cerebral artery bypass....

journal_title：Journal of neurosurgery

authors： Kurihara H,Yamaguchi K,Ishikawa T,Funatsu T,Matsuoka G,Omura Y,Okada Y,Kawamata T

更新日期：2019-08-23 00:00:00

abstract：:OBJECTIVE In severe traumatic brain injury (TBI), the effects of decompressive craniectomy (DC) on brain tissue oxygen pressure (PbtO2) and outcome are unclear. The authors aimed to investigate whether changes in PbtO2 after DC could be used as an independent prognostic factor. METHODS The authors conducted a retrospe...

journal_title：Journal of neurosurgery

authors： Lubillo ST,Parrilla DM,Blanco J,Morera J,Dominguez J,Belmonte F,López P,Molina I,Ruiz C,Clemente FJ,Godoy DA

更新日期：2018-05-01 00:00:00

abstract：:The results of anterior cervical surgery for treatment of cervical spondylotic myelopathy (CSM) are assessed 1 to 7 years postoperatively in 32 patients. At follow-up review, 50% were improved after surgery and 50% were unimproved or had deteriorated in spite of surgery. The results could not be statistically linked t...

journal_title：Journal of neurosurgery

authors： Lunsford LD,Bissonette DJ,Zorub DS

更新日期：1980-07-01 00:00:00

abstract：OBJECT:The authors studied the microsurgical anatomy of the ophthalmic artery (OphA), paying particular attention to its possibly dangerous anastomoses with the middle meningeal artery (MMA). METHODS:The microsurgical anatomy of the OphA and its anastomoses with the MMA were studied in 14 vessels from seven adult cada...

journal_title：Journal of neurosurgery

authors： Perrini P,Cardia A,Fraser K,Lanzino G

更新日期：2007-01-01 00:00:00

abstract：:Superior oblique myokymia (SOM) is a rare eye movement disorder presenting as uniocular rotatory microtremor due to intermittent contractions of the superior oblique muscle. Medical treatment usually fails to provide long-term benefit for the patient and has considerable side effects. Surgical alternatives including t...

journal_title：Journal of neurosurgery

authors： Samii M,Rosahl SK,Carvalho GA,Krzizok T

更新日期：1998-12-01 00:00:00

abstract：:OBJECTIVE Chronic neuropathic pain after peripheral nerve injury is a major clinical problem. Its management is difficult, and therapeutic approaches vary and include oral medication, neurostimulation, and surgery. The aim of this study was to assess the adequacy of surgical nerve revision in a large series of patient...

journal_title：Journal of neurosurgery

authors： Decrouy-Duruz V,Christen T,Raffoul W

更新日期：2018-04-01 00:00:00

abstract：:Space-occupying lesions of the basal ganglia are a rare cause of extrapyramidal dysfunction in children. Metastatic pineal germinoma in both basal ganglia produced dystonia in a 12-year-old boy. The literature is reviewed. Extrapyramidal manifestations in the child are compared with previously reported cases of basal ...

journal_title：Journal of neurosurgery

authors： Lins MM,McDonnell DE,Aschenbrener CA,Cancilla PA

更新日期：1978-01-01 00:00:00

abstract：OBJECT:Recent advances in neuroradiology have made it possible to dilate vasospastic human cerebral arteries after aneurysmal subarachnoid hemorrhage (SAH), but the time window is short and the success rate for reversal of delayed ischemic neurological deficits (DINDs) varies between 31% and 77%. In a dog model of vaso...

journal_title：Journal of neurosurgery

authors： Muizelaar JP,Zwienenberg M,Rudisill NA,Hecht ST

更新日期：1999-07-01 00:00:00

abstract：:Cerebral blood flow (CBF) was measured at different times during the first 150 minutes following an experimental space-occupying lesion produced with a 50-microliter microballoon in rats. Local CBF was measured with the carbon-14-labeled iodoantipyrine quantitative autoradiographic technique. A region of local ischemi...

journal_title：Journal of neurosurgery

authors： Kingman TA,Mendelow AD,Graham DI,Teasdale GM

更新日期：1987-11-01 00:00:00

abstract：:OBJECTIVEThe purpose of this study was to analyze national trends in adult cranial cases performed by neurological surgery residents as logged into the Accreditation Council for Graduate Medical Education (ACGME) system.METHODSThe ACGME resident case logs were retrospectively reviewed for the years 2009-2017. In these...

journal_title：Journal of neurosurgery

authors： Agarwal N,White MD,Cohen J,Lunsford LD,Hamilton DK

更新日期：2018-07-01 00:00:00

abstract：:Melanocytomas are rare tumors of the central nervous system that are believed to arise from leptomeningeal melanocytes. A young girl presented with a contrast-enhancing cystic mass in the temporal horn of the left lateral ventricle. Microsurgical resection of a black-colored vascular tumor supplied by the anterior cho...

journal_title：Journal of neurosurgery

authors： Tandon N,O'Neill TJ,Vollmer DG,Wang M

更新日期：2008-09-01 00:00:00

abstract：:OBJECT The frontal and insular fiber network in humans remains largely unknown. This study investigated the connectivity of the frontal and anterior insular network in humans using cortico-cortical evoked potential (CCEP). METHODS This retrospective analysis included 18 patients with medically intractable focal epilep...

journal_title：Journal of neurosurgery

authors： Enatsu R,Gonzalez-Martinez J,Bulacio J,Mosher JC,Burgess RC,Najm I,Nair DR

更新日期：2016-07-01 00:00:00

abstract：OBJECT:Resection of cancer and the involved artery in the neck has been applied with some success, but the indications for such an aggressive approach at the skull base are less well defined. The authors therefore evaluated the outcomes of advanced skull base malignancies in patients who were treated with bypass and re...

journal_title：Journal of neurosurgery

authors： Kalani MY,Kalb S,Martirosyan NL,Lettieri SC,Spetzler RF,Porter RW,Feiz-Erfan I

更新日期：2013-03-01 00:00:00

abstract：OBJECT:The objective of the present study was to perform a prospective evaluation of the potential efficacy and safety of intraoperative photodynamic therapy (PDT) using talaporfin sodium and irradiation using a 664-nm semiconductor laser in patients with primary malignant parenchymal brain tumors. METHODS:In 27 patie...

journal_title：Journal of neurosurgery

authors： Muragaki Y,Akimoto J,Maruyama T,Iseki H,Ikuta S,Nitta M,Maebayashi K,Saito T,Okada Y,Kaneko S,Matsumura A,Kuroiwa T,Karasawa K,Nakazato Y,Kayama T

更新日期：2013-10-01 00:00:00

abstract：:A 6-year-old girl with a history of a nondisplaced skull fracture diagnosed with computerized tomography (CT) scanning 3 years previously presented with a 6-week history of headaches and decreased use of her right side. On admission CT scans, a large cystic mass was identified in the left frontal lobe region of the br...

journal_title：Journal of neurosurgery

authors： Carter AB,Price DL Jr,Tucci KA,Lewis GK,Mewborne J,Singh HK

更新日期：2001-12-01 00:00:00

abstract：:OBJECT In patients with hydrocephalus and shunts, lasting symptoms such as headache and dizziness may be indicative of shunt failure, which may necessitate shunt revision. In cases of doubt, the authors monitor intracranial pressure (ICP) to determine the presence of over- or underdrainage of CSF to tailor management....

journal_title：Journal of neurosurgery

authors： Sæhle T,Eide PK

更新日期：2015-05-01 00:00:00

abstract：:The therapeutic application of barbiturate-induced coma was evaluated in a primate model of focal cerebral ischemia. A standardized regimen of pentobarbital was used, and the times of initiation of administration were varied following a 6-hour middle cerebral artery occlusion in baboons. Three groups of five animals w...

journal_title：Journal of neurosurgery

authors： Selman WR,Spetzler RF,Roski RA,Roessmann U,Crumrine R,Macko R

更新日期：1982-05-01 00:00:00

abstract：:Experimental contusion paraplegic injury to the posterior spinal cord in cats results in a sudden increase of systemic blood pressure to between 200 and 250 mm Hg, and an increase in pulse pressure and a slowing of pulse rate. This initial hypertensive phase lasts approximately 3 to 4 minutes, and then is followed by ...

journal_title：Journal of neurosurgery

authors： Rawe SE,Perot PL Jr

更新日期：1979-01-01 00:00:00

abstract：:OBJECTIVE The vascular lumen of an acutely occluded internal carotid artery (ICA) generally contains numerous thrombi. Therefore, carotid angiography on the affected side during revascularization therapy of acute ICA occlusion has a potential risk of causing distal embolization. In this study the authors propose the u...

journal_title：Journal of neurosurgery

authors： Tsuji K,Nakagawa N,Fukawa N,Miyauchi M,Furukawa K,Nakanishi K,Nakano N,Kataoka K,Kato A

更新日期：2018-08-01 00:00:00

abstract：:Forty-seven patients with medulloblastoma were treated postoperatively with procarbazine, followed by craniospinal radiation therapy in combination with hydroxyurea. The radiation dose to the posterior fossa was 55 Gy; the spinal cord received 25 Gy and the whole brain 25 to 35 Gy (mean 33 Gy). Seventeen tumors recurr...

journal_title：Journal of neurosurgery

authors： Levin VA,Rodriguez LA,Edwards MS,Wara W,Liu HC,Fulton D,Davis RL,Wilson CB,Silver P

更新日期：1988-03-01 00:00:00

abstract：OBJECT:Disturbance of calcium homeostasis contributes to evolving tissue damage and energetic impairment following traumatic brain injury (TBI). Calcium-mediated activation of calcineurin results in production of tissue-damaging nitric oxide and free oxygen radicals. Inhibition of calcineurin induced by the immunosuppr...

journal_title：Journal of neurosurgery

authors： Stover JF,Schöning B,Sakowitz OW,Woiciechowsky C,Unterberg AW

更新日期：2001-05-01 00:00:00

abstract：:The acquired immune deficiency syndrome (AIDS) is a recently described T-cell deficiency predisposing patients to a spectrum of opportunistic infections. Kaposi's sarcoma, and other neoplasms. It appears primarily among homosexual males and intravenous drug abusers, but is now being observed in other groups as well. T...

journal_title：Journal of neurosurgery

authors： Handler M,Ho V,Whelan M,Budzilovich G

更新日期：1983-12-01 00:00:00

abstract：:In 10 patients with supratentorial ependymomas, the tumors exhibited hyperdensity on computerized tomography (CT) scanning prior to contrast infusion and, with one exception, all tumors were mixed lesions with the low densities suggesting cystic or necrotic portions. Eighty percent of the tumors contained small calcif...

journal_title：Journal of neurosurgery

authors： Centeno RS,Lee AA,Winter J,Barba D

更新日期：1986-02-01 00:00:00

abstract：:The magnetic resonance longitudinal relaxation time (T1) and transverse relaxation time (T2) of the water proton of the periventricular white and cortical gray matter were measured for 17 control patients and 21 patients with suspected normal-pressure hydrocephalus (NPH). Of the latter group, 14 showed good response t...

journal_title：Journal of neurosurgery

authors： Tamaki N,Shirakuni T,Ehara K,Matsumoto S

更新日期：1990-12-01 00:00:00

abstract：OBJECT:The authors experienced an intriguing phenomenon in 2 adult patients with moyamoya disease. Mouth opening caused reversible occlusion of the donor superficial temporal artery (STA), and the patients exhibited transient cerebral ischemic symptoms. The aim of this study was to assess the incidence of such occlusio...

journal_title：Journal of neurosurgery

authors： Katsuta T,Abe H,Miki K,Inoue T

更新日期：2015-09-01 00:00:00

abstract：OBJECT:Cavernomas in the occipital lobe are relatively rare. Because of the proximity to the visual cortex and incoming subcortical tracts, microsurgical removal of occipital cavernomas may be associated with a risk of visual field defects. The goal of the study was to analyze long-term outcome after operative treatmen...

journal_title：Journal of neurosurgery

authors： Kivelev J,Koskela E,Setälä K,Niemelä M,Hernesniemi J

更新日期：2012-08-01 00:00:00

abstract：:Mongrel dogs with experimental spinal cord injury were treated with the carotenoid compound crocetin. It has been shown that crocetin increases the diffusion speed of oxygen through plasma, and should provide a net increase in oxygen at the level of the capillary endothelial cell. The treated animals showed a signific...

journal_title：Journal of neurosurgery

authors： Gainer JV Jr

更新日期：1977-03-01 00:00:00

abstract：:The effect of clot removal on cerebral vasospasm was studied in 104 patients with aneurysmal subarachnoid hemorrhage (SAH). The series included patients who fulfilled all of the following criteria: operation was performed by Day 3 after the ictus; the patient's preoperative clinical grade was between Grades I and IV; ...

journal_title：Journal of neurosurgery

authors： Inagawa T,Yamamoto M,Kamiya K

更新日期：1990-02-01 00:00:00

abstract：OBJECT:Recurrent malignant gliomas have inherent resistance to traditional chemotherapy. Novel therapies target specific molecular mechanisms involved in abnormal signaling and resistance to apoptosis. The proteasome is a key regulator of multiple cellular functions, and its inhibition in malignant astrocytic lines cau...

journal_title：Journal of neurosurgery

authors： Bota DA,Alexandru D,Keir ST,Bigner D,Vredenburgh J,Friedman HS

更新日期：2013-12-01 00:00:00

abstract：:An anatomical study of three microsurgical intraorbital routes to the optic nerve and orbital apex, which can be reached through a fronto-orbital craniotomy, was conducted on cadaver specimens. The structures that could be exposed via the medial, central, or lateral approaches directed through the orbital roof were de...

journal_title：Journal of neurosurgery

authors： Natori Y,Rhoton AL Jr

更新日期：1994-07-01 00:00:00