Abstract:
:The visual cycle system in a primitive chordate, ascidian Ciona intestinalis, was studied by whole-mount in situ hybridization and by whole-mount immunohistochemistry. Three visual cycle proteins, Ciona homologue of RGR (Ci-opsin3), CRALBP (Ci-CRALBP), and BCO/RPE65 (Ci-BCO/RPE65) were widely distributed in the brain vesicle and visceral ganglion. To identify the visual cycle system in a primitive chordate, we compared the localization of photoreceptor-specific proteins (visual pigment and arrestin) and visual cycle proteins (Ci-opsin3 and Ci-CRALBP). The ascidian visual cycle is composed of two cellular compartments, the photoreceptors and the brain vesicle, but some photoreceptor cells also contain visual cycle proteins.
journal_name
Vision Resjournal_title
Vision researchauthors
Tsuda M,Kusakabe T,Iwamoto H,Horie T,Nakashima Y,Nakagawa M,Okunou Kdoi
10.1016/j.visres.2003.09.012subject
Has Abstractpub_date
2003-12-01 00:00:00pages
3045-53issue
28eissn
0042-6989issn
1878-5646pii
S0042698903005546journal_volume
43pub_type
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