当前位置： SCI文献检索 > JOURNAL OF PEDIATRIC SURGERY期刊下所有文献 > Inflammatory changes secondary to postoperative complications of Hirschsprung's disease as a cause of histopathologic changes typical of intestinal neuronal dysplasia.

Inflammatory changes secondary to postoperative complications of Hirschsprung's disease as a cause of histopathologic changes typical of intestinal neuronal dysplasia.

Abstract：

PURPOSE:The aim of this study was to clarify the pathogenesis of intestinal neuronal dysplasia (IND). METHODS:The bowel habits of 36 postoperative HD patients were assessed retrospectively. Twenty-five had no complaints. Seven had persistent enterocolitis and were the focus of our study. They were divided into group A (n = 2) if they were severe and had associated postoperative surgical complications, and group B (n = 5) if they were mild. The histological changes were assessed. RESULTS:The 7 patients who had persistent enterocolitis postoperatively had no AchE activity in the mucosa, and there was normal distribution of submucosal and myenteric ganglia in the proximal resection margin. Rectal biopsies performed postoperatively for investigation of persistent enterocolitis in group A showed inflammatory changes and typical histopathologic features of IND such as abundant acetylcholinesterase (AchE)-positive nerve fibers in the lamina propria associated with giant submucosal ganglia and hyperganglionosis, and in group B there was increased AchE activity without hyperganglionosis or giant ganglia. CONCLUSIONS:This is the first report of histopathologic changes typical of IND occurring in response to persistent enterocolitis related to postoperative complications of surgery for HD.

journal_name

J Pediatr Surg

journal_title

Journal of pediatric surgery

authors

Kobayashi H,Yamataka A,Lane GJ,Miyano T

doi

10.1016/j.jpedsurg.2003.10.008

subject

Has Abstract

pub_date

2004-02-01 00:00:00

pages

152-6; discussion 152-6

issue

2

eissn

0022-3468

issn

1531-5037

pii

S0022346803007978

journal_volume

39

pub_type

杂志文章

相关文献

JOURNAL OF PEDIATRIC SURGERY文献大全
  • Preventable pediatric trauma deaths in a metropolitan region.

    abstract：:All pediatric trauma deaths occurring in metropolitan Toronto (population, 2.2 million) in 1986 were analyzed from the regional coroner's records. Injuries sustained were scored using the Abbreviated Injury Scale (1985; AIS) and Injury Severity Score (ISS). Victims with injuries graded AIS 6 (any region), AIS 5 head/n...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(89)80312-4

    authors： Dykes EH,Spence LJ,Young JG,Bohn DJ,Filler RM,Wesson DE

    更新日期：1989-01-01 00:00:00

  • Short-term intravenous fish oil and pediatric intestinal failure associated liver disease: 3-year follow-up on liver function and nutrition.

    abstract：:Intravenous fish oil (FO) has changed the management of intestinal failure associated liver disease (IFALD). This report describes two IFALD patients who received FO for 5 and 10 months, respectively and reports on their 3-year follow-up. ...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2012.10.044

    authors： Calkins K,Lowe A,Shew SB,Dunn JC,Reyen L,Farmer DG,Devaskar SU,Venick R

    更新日期：2013-01-01 00:00:00

  • Endoscopic management of recurrent tracheoesophageal fistula.

    abstract：RATIONALE:Recurrent tracheoesophageal fistulas (RTEFs) remain a therapeutic challenge because open surgical approaches have been associated with substantial rates of morbidity, mortality, and repeat recurrences. Recently, endoscopic techniques for the repair of RTEF have provided an alternative approach with the potent...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2007.08.062

    authors： Richter GT,Ryckman F,Brown RL,Rutter MJ

    更新日期：2008-01-01 00:00:00

  • Prenatal ultrasonographic gastrointestinal abnormalities in fetuses with gastroschisis do not correlate with postnatal outcomes.

    abstract：PURPOSE:In the setting of gastroschisis, the clinical significance of prenatal ultrasound findings of secondary changes in bowel appearance remains unknown. The purpose of this study was to correlate prenatal identification of additional gastrointestinal sonographic abnormalities with postnatal clinical outcome. METHO...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2007.09.016

    authors： Badillo AT,Hedrick HL,Wilson RD,Danzer E,Bebbington MW,Johnson MP,Liechty KW,Flake AW,Adzick NS

    更新日期：2008-04-01 00:00:00

  • Ruptured rectal duplication cyst with classical bladder exstrophy.

    abstract：:A newborn boy was brought to us, 2 hours after birth, with a mucosal-lined left hemiperineal lesion associated with classical bladder exstrophy and an anterolaterally displaced anus. Perineal anatomy was restored by excising the mucosa lined lesion. The bladder closure for classical bladder exstrophy was done at the s...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2010.03.012

    authors： Gupta RK,Oak S,Parelkar SV,Sanghvi B,Kaltari DK,Prakash A,Patil R,Bachani M

    更新日期：2010-07-01 00:00:00

  • The embryology of foregut malformations.

    abstract：:Developmental disorders in the period of the differentiation of the primitive foregut leads to atresia of the esophagus with tracheoesophageal fistula. Most authors think that this differentiation is caused by lateral foregut folds, which fuse in midline, thus forming the tracheoesophageal septum. In order to gain inf...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(87)80254-3

    authors： Kluth D,Steding G,Seidl W

    更新日期：1987-05-01 00:00:00

  • Surgical evaluation of lymph node metastases in Wilms' tumor.

    abstract：:Because lymph node (LN) involvement continues to be an adverse prognostic factor in the later National Wilms' Tumor Study (NWTS) trials, the NWTS-3 Surgical Committee undertook a project to determine the accuracy of the present method of sampling. The committee concludes that: (1) there is a relatively low potential e...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/0022-3468(90)90079-o

    authors： Othersen HB Jr,DeLorimer A,Hrabovsky E,Kelalis P,Breslow N,D'Angio GJ

    更新日期：1990-03-01 00:00:00

  • Intralesional corticosteroid therapy in proliferating head and neck hemangiomas: a review of 155 cases.

    abstract：PURPOSE:The purpose of this paper is to review the effect of intralesional corticosteroid therapy in the treatment of 155 head and neck hemangiomas. METHODS:In the past 10 years, we have treated 155 proliferating head and neck hemangiomas with intralesional corticosteroid injections. Three to 6 injections of triamcino...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(00)90205-7

    authors： Chen MT,Yeong EK,Horng SY

    更新日期：2000-03-01 00:00:00

  • Health-related quality of life in adult patients with esophageal atresia--a questionnaire study.

    abstract：BACKGROUND/PURPOSE:Long-term sequelae caused by associated anomalies or respiratory and gastrointestinal disorders are common after the repair of esophageal atresia (EA). The aim of this study was to assess the effect of these sequelae on the health-related quality of life (HRQoL) of patients with EA. METHODS:A questi...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2004.10.014

    authors： Koivusalo A,Pakarinen MP,Turunen P,Saarikoski H,Lindahl H,Rintala RJ

    更新日期：2005-02-01 00:00:00

  • Respiratory hydrogen secretion: a simple test of bowel adaptation in infants with short gut syndrome.

    abstract：:The prime goal in the management of infants with short gut syndrome is the smooth transition from total parenteral alimentation to total gastrointestinal alimentation. Such transition is dependent upon early feeding to actively promote the intestinal mucosal hyperplasia that is the key to eventual oral alimentation. A...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(81)80678-1

    authors： Shermeta DW,Ruaz E,Fink BB,MacLean WC Jr

    更新日期：1981-06-01 00:00:00

  • Comparative analysis of successful and unsuccessful candidates for the pediatric surgical matching program.

    abstract：:Only one third of the applicants for training in pediatric surgery obtain a position through the pediatric surgery matching program. In order to identify factors that contribute to a successful outcome, we conducted a retrospective survey of all participants in the matching process for positions during the years 1983 ...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/0022-3468(92)90302-n

    authors： Hirthler MA,Glick PL,Hassett JM Jr,Rossman J,Mendola P,Allen JE,Jewett TC Jr,Cooney DR

    更新日期：1992-02-01 00:00:00

  • Late fatal hemorrhage in pediatric liver trauma.

    abstract：:The cumulative evidence supports nonoperative management of hepatic trauma in children who are hemodynamically stable and who require less than 50% blood volume replacement to maintain a stable blood count. This management approach, based on the use of either serial computed tomography scans, liver/spleen scans, or ul...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/0022-3468(92)90503-y

    authors： Berman SS,Mooney EK,Weireter LJ Jr

    更新日期：1992-12-01 00:00:00

  • Intestinal failure-associated liver disease in surgical infants requiring long-term parenteral nutrition.

    abstract：PURPOSE:Our aim was to determine incidence, severity, and outcome, as well as predisposing factors and underlying diagnoses, of intestinal failure-associated liver disease (IFALD) in surgical infants requiring long-term parenteral nutrition (PN). METHODS:We retrospectively studied surgical infants receiving PN for at ...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2011.11.032

    authors： Bishay M,Pichler J,Horn V,Macdonald S,Ellmer M,Eaton S,Hill S,Pierro A

    更新日期：2012-02-01 00:00:00

  • Approach to cervicothoracic neuroblastomas via a trap-door incision.

    abstract：:Neuroblastomas located in the apex of the hemithorax or in the lower cervical region may make complete resection via a cervical or a thoracic approach difficult. The authors recently managed two patients with cervicothoracic neuroblastomas through an approach using the trap-door incision often applied in the setting o...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/0022-3468(95)90127-2

    authors： Pranikoff T,Hirschl RB,Schnaufer L

    更新日期：1995-04-01 00:00:00

  • Management of children and adolescents with a critical airway due to compression by an anterior mediastinal mass.

    abstract：:This study used retrospective review of patients with critical airway due to compression by an anterior mediastinal mass treated at a single pediatric teaching institution. Diagnostic workup is reviewed with a focus on diagnostic biopsy. Algorithm for streamlining the choice of biopsy technique and minimizing invasive...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2008.02.083

    authors： Perger L,Lee EY,Shamberger RC

    更新日期：2008-11-01 00:00:00

  • A Canadian national survey: understanding the differences in management of cryptorchidism among pediatric surgeons and pediatric urologists.

    abstract：BACKGROUND:This investigation aims to assess the variability in practice patterns regarding management of children with cryptorchidism (UDT) among pediatric urologists (U) and pediatric surgeons (S) practicing in Canada. METHODS:All active members of Pediatric Urologists of Canada (PUC) and Canadian Association of Ped...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2018.10.053

    authors： Kim JK,Chua M,Braga L,Langer JC,Hancock BJ,Lorenzo AJ,Bagli D,Farhat WA,Koyle MA

    更新日期：2019-09-01 00:00:00

  • Neutropenic enterocolitis as a presenting complication of acute lymphoblastic leukemia: an unusual case marked by delayed perforation of the descending colon.

    abstract：:Neutropenic enterocolitis (NE) is a life-threatening complication most commonly seen in patients receiving intensive chemotherapy for acute leukemia. The condition usually affects the terminal ileum, cecum, or ascending colon. In rare instances, NE may occur before the initiation of chemotherapy or involve more distal...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2004.03.083

    authors： Wilson DB,Rao A,Hulbert M,Mychaliska KP,Luchtman-Jones L,Hill DA,Foglia RP

    更新日期：2004-07-01 00:00:00

  • Cholelithiasis in newborns and infants.

    abstract：:Cholelithiasis in infants is rare, and has usually been associated with hemolysis, ileal disease, congenital anomalies of the biliary tree, hyperalimentation, and prolonged fasting. With the increased use of abdominal ultrasonography (US), more cases of cholelithiasis are being discovered. We report our experience wit...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/0022-3468(92)90281-b

    authors： St-Vil D,Yazbeck S,Luks FI,Hancock BJ,Filiatrault D,Youssef S

    更新日期：1992-10-01 00:00:00

  • Recombinant human interleukin-11 prevents mucosal atrophy and bowel shortening in the defunctionalized intestine.

    abstract：BACKGROUND:Mucosal atrophy and bowel shortening are the hallmark of proximal intestinal diversion for extensive necrotizing enterocolitis (NEC) or Thiry-Vella fistulas (TVF), in which the ends of a defunctionalized loop of intestine are exteriorized as stomas. Recombinant human interleukin-11 (rhIL-11) is a pleiotropic...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1053/jpsu.2000.7826

    authors： Dickinson EC,Tuncer R,Nadler EP,Koltuksuz U,Boyle P,Alber SM,Watkins SC,Ford HR

    更新日期：2000-07-01 00:00:00

  • Case report of an 11-year-old child with a nonfunctional malignant pheochromocytoma.

    abstract：:Pheochromocytoma is an unusual cause of surgical hypertension and is extremely rare in the pediatric population. We present a case of a hypertension-producing malignant pheochromocytoma in an 11-year-old, which was initially unresectable. The tumor responded partially to aggressive chemotherapy and was completely rese...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2007.08.046

    authors： Holwitt D,Neifeld J,Massey G,Lanning D

    更新日期：2007-11-01 00:00:00

  • Predicting the outcome of newborns with gastroschisis.

    abstract：OBJECTIVE:The objective of the study was to determine factors predicting outcome in newborns with gastroschisis. METHODS:A retrospective analysis of 155 consecutive cases admitted from 1 January 1990 to 31 December 2007 was performed. Prenatal ultrasound findings were available for 89 of 155 (57%) patients and were co...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2009.01.036

    authors： Payne NR,Pfleghaar K,Assel B,Johnson A,Rich RH

    更新日期：2009-05-01 00:00:00

  • Reoperation for anastomotic complications of esophageal atresia and tracheoesophageal fistula.

    abstract：BACKGROUND/PURPOSE:The purpose of the study was to review our experience in the re-operative management of anastomotic complications (ACs) following primary repair of esophageal atresia (EA) and tracheoesophageal fistula (TEF) and to assess the outcomes after reoperation. METHODS:We retrospectively reviewed 21 EA pati...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2015.08.015

    authors： Zhu H,Shen C,Xiao X,Dong K,Zheng S

    更新日期：2015-12-01 00:00:00

  • The structural characteristics and expression of neuropeptides in the esophagus of patients with congenital esophageal atresia and tracheoesophageal fistula.

    abstract：PURPOSE:The aim of this study was to investigate the structural characteristics and the expression of a group of neuropeptides in the esophagus of patients with congenital esophageal atresia and tracheoesophageal fistula (EA-TEF), as well to elucidate the roles of these neuropeptides in the pathogenesis of postoperativ...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2007.03.050

    authors： Li K,Zheng S,Xiao X,Wang Q,Zhou Y,Chen L

    更新日期：2007-08-01 00:00:00

  • Mortality among infants with high-risk congenital diaphragmatic hernia in Singapore.

    abstract：:Several factors suggested to predict mortality in congenital diaphragmatic hernia (CDH) have not always been applicable in different centers. A retrospective review was conducted of 19 consecutive neonates in Singapore in whom CDH was diagnosed within 12 hours of birth to identify factors associated with mortality. Of...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(97)90104-4

    authors： Chan DK,Ho LY,Joseph VT

    更新日期：1997-01-01 00:00:00

  • Imperforate anus associated with a recto-bulbar-cutaneous fistula.

    abstract：:This is the report of two newborn boys with imperforate anus associated with a long rectocutaneous fistula running deep into the scrotum and communicating, in its midportion, with the bulbar urethra. The findings are compared with those of a somewhat similar case in the literature, with some speculations as to the pos...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/0022-3468(94)90535-5

    authors： Currarino G

    更新日期：1994-01-01 00:00:00

  • Laryngotracheal disruption from blunt pediatric neck injuries: impact of early recognition and intervention on outcome.

    abstract：:Blunt and penetrating neck injuries are an infrequent cause of morbidity and mortality in the pediatric population. Although less common than penetrating injuries, blunt pediatric neck injuries are more often life-threatening because of associated laryngotracheal disruption. The authors reviewed their experience with ...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/0022-3468(95)90584-7

    authors： Ford HR,Gardner MJ,Lynch JM

    更新日期：1995-02-01 00:00:00

  • Congenital pancreatic pseudocyst: report of two cases.

    abstract：:Pancreatic pseudocysts have not been reported to occur in the fetus or newborn. The authors report two cases of histologically proven pancreatic pseudocysts in neonates, which were detected using prenatal ultrasonography. Surgical management included external marsupialization followed by internal drainage in one case,...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/s0022-3468(96)90185-2

    authors： Kurrer MO,Ternberg JL,Langer JC

    更新日期：1996-11-01 00:00:00

  • Inhaled nitric oxide inhibits the release of matrix metalloproteinase-2, but not platelet activation, during extracorporeal membrane oxygenation in adult rabbits.

    abstract：BACKGROUND/PURPOSE:In neonates receiving extracorporeal membrane oxygenation (ECMO), platelet activation and dysfunction occur with the release of matrix metalloproteinase (MMP)-2, which stimulates platelet aggregation. Because inhaled nitric oxide (NO) reduces pulmonary hypertension and inhibits platelet aggregation, ...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1053/jpsu.2003.50116

    authors： Cheung PY,Sawicki G,Peliowski A,Etches PC,Schulz R,Radomski MW

    更新日期：2003-04-01 00:00:00

  • Rates and risk factors of unplanned 30-day readmission following general and thoracic pediatric surgical procedures.

    abstract：BACKGROUND/PURPOSE:Postoperative unplanned readmissions are costly and decrease patient satisfaction; however, little is known about this complication in pediatric surgery. The purpose of this study was to determine rates and predictors of unplanned readmission in a multi-institutional cohort of pediatric surgical pati...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2016.11.043

    authors： Polites SF,Potter DD,Glasgow AE,Klinkner DB,Moir CR,Ishitani MB,Habermann EB

    更新日期：2017-08-01 00:00:00

  • Appendiceal fecalith is associated with early perforation in pediatric patients.

    abstract：PURPOSE:A fecalith is a fecal concretion that can obstruct the appendix leading to acute appendicitis. We hypothesized that the presence of a fecalith would lead to an earlier appendiceal perforation. METHODS:Between January 2001 and December 2005, the charts of all patients younger than 18 years old who underwent app...

    journal_title：Journal of pediatric surgery

    pub_type： 杂志文章

    doi：10.1016/j.jpedsurg.2007.12.034

    authors： Alaedeen DI,Cook M,Chwals WJ

    更新日期：2008-05-01 00:00:00