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Outcome and complications after resection of hepatoblastoma.

Abstract：

PURPOSE:The aim of this study was to review the outcome and complications after resection of hepatoblastoma treated over 2 decades in our institution. METHODS:Clinical, radiologic, and pathologic data were reviewed retrospectively, focusing on the outcome and complications. RESULTS:Between January 1978 and December 2002, 56 children were treated for hepatoblastoma. The age range was 0.08 to 8.74 years (median, 1 year). The right lobe was involved in 48%, the left lobe in 22%, and in 29% the main bulk of the tumour was centrally located. Surgical procedures included the following: hemihepatectomy in 62%, trisegmentectomy in 18%, extended hemihepatectomy in 16%, and liver transplantation and laparotomy in one patient each. Intraoperative complications occurred in 5(9%)--rupture of the tumour (1), haemorrhage from the contralateral lobe (1), a defect in the left hepatic duct (1), cardiac arrest from tumour embolus (1), and bleeding from the inferior vena cava (1). The mean blood loss was 280 mL (50 to 2,000 mL). Postoperative complications occurred in 12 patients (22%) including subphrenic abscess (3), adhesion obstruction (2), ischaemic stenosis of the bile duct (1), abdominal wound dehiscence (1), pyloric obstruction (1), and pleural effusion (2). Fifteen patients died, 14 as a result of tumour recurrence (mortality rate, 27%).

journal_name

J Pediatr Surg

journal_title

Journal of pediatric surgery

authors

Towu E,Kiely E,Pierro A,Spitz L

doi

10.1016/j.jpedsurg.2003.10.013

subject

Has Abstract

pub_date

2004-02-01 00:00:00

pages

199-202; discussion 199-202

issue

2

eissn

0022-3468

issn

1531-5037

pii

S0022346803008029

journal_volume

39

pub_type

杂志文章,评审

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