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Unresectable multifocal omental and peritoneal inflammatory myofibroblastic tumor in a child: revisiting the role of adjuvant therapy.

Abstract：

:Inflammatory myofibroblastic tumor is an uncommon lesion, also called pseudotumor, with a variable natural course from benign with spontaneous regression to mimicking malignant tumors. We report a case of diffuse peritoneal and omental pseudotumor in a 10-year-old boy characterized by aggressive behavior at the onset followed by stability after subtotal resection and chemotherapy. Total excision was not possible because of the tumor dissemination over the whole peritoneal surface. Adjuvant antiinflammatory drug (ketorolac tromethamine) and chemotherapy (methotrexate-vinblastine followed by ifosfamide-adriamycin and ifosfamide alone) were helpful to obtain rapidly complete resolution of clinical symptoms and anatomic stability of the residual lesions. Long-term evolution, in the absence of continued therapy, has been characterized by progressive involution and reduction of the residual masses.

journal_name

J Pediatr Surg

journal_title

Journal of pediatric surgery

authors

Bertocchini A,Lo Zupone C,Callea F,Gennari F,Serra A,Monti L,de Ville de Goyet J

doi

10.1016/j.jpedsurg.2011.01.007

subject

Has Abstract

pub_date

2011-04-01 00:00:00

pages

e17-e21

issue

4

eissn

0022-3468

issn

1531-5037

pii

S0022-3468(11)00048-0

journal_volume

46

pub_type

杂志文章

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