Abstract：
:It is undeniable that most patients with advanced ovarian cancer derive benefit from primary cytoreductive surgery, with relief of symptoms, prolonged survival, improved quality of life, and establishment of a definitive diagnosis. Several questions, however, remain unanswered, including the relative effects of surgical intervention and tumor biology and the benefit of ultraradical debulking with or without technologic advances, such as the CUSA or laser therapy. Future studies will likely clarify many issues, including the therapeutic index of neoadjuvant chemotherapy and interval debulking compared with standard treatment and the impact of debulking within homogeneous cohorts of patients (i.e., stage IIIc) with similar host factors.
journal_name
Obstet Gynecol Clin North Amjournal_title
Obstetrics and gynecology clinics of North Americaauthors
Gershenson DMsubject
Has Abstractpub_date
1994-03-01 00:00:00pages
121-40issue
1eissn
0889-8545issn
1558-0474journal_volume
21pub_type
杂志文章,评审abstract：:The normal vaginal, or resident, flora is complex and easily includes over a dozen different organisms, many of them potential pathogens. The quantitative nature of the vaginal flora also is a factor in development of symptoms. This complex milieu is further varied by nature's changes over the years from birth to meno...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1989-06-01 00:00:00
abstract：:Women who use tobacco, alcohol and drugs during pregnancy are at increased risk of maternal and fetal morbidity. Universal screening using empirically validated approaches can improve identification of substance-using pregnant women and facilitate comprehensive assessment of treatment needs. There is strong evidence f...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2014.03.001
更新日期：2014-06-01 00:00:00
abstract：:This article details the indicators, techniques, and anticipated success rates of laser surgery for vulvar condylomas and neoplasias. The role of adjuvant 5-fluorouracil and interferon is also discussed. ...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1991-09-01 00:00:00
abstract：:The serum CA-125 level is elevated in most women with endometriosis. Although tests are readily available to measure the marker, simple modifications of the present assays are required to improve and standardize the quality of the measurements. The serum test has low sensitivity and would not be appropriate for genera...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1989-03-01 00:00:00
abstract：:Interstitial cystitis, or painful bladder syndrome, can present with lower abdominal pain/discomfort and dyspareunia, and pain in any distribution of lower spinal nerves. Patients with this condition experience some additional symptoms referable to the bladder, such as frequency, urgency, or nocturia. It can occur acr...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2014.05.004
更新日期：2014-09-01 00:00:00
abstract：:A review of all relevant randomized controlled trials provides strong evidence that corticosteroid therapy causes a significant reduction in respiratory distress syndrome (RDS) in preterm babies overall. This reduction in RDS is accompanied by a reduced incidence of neonatal death, intraventricular hemorrhages, and ne...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 临床试验,杂志文章,随机对照试验,评审
doi：
更新日期：1992-06-01 00:00:00
abstract：:The introduction of transabdominal fiberoptic thin-gauge visualization of the embryo or fetus in the first trimester allows an earlier diagnosis of congenital anomalies currently beyond the resolution of ultrasound. In addition, it has the true potential of providing access to the fetal circulation at an early age, an...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1993-09-01 00:00:00
abstract：:The influence of physiologic, psychologic, and cultural influences on human sexuality is reviewed. These factors are considered in the exploration of how adolescents express their sexuality and the consequences of that expression. ...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1992-03-01 00:00:00
abstract：:Abnormal uterine bleeding in the reproductive age, that is, dysfunctional uterine bleeding, is a very common symptom encountered in office gynecology. The judicious use of hysteroscopy to manage this medical entity adds a new dimension in handling this often perplexing problem. This article focuses mainly on abnormal ...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章
doi：
更新日期：1988-03-01 00:00:00
abstract：:Except in special circumstances, therapeutic insemination with a husband's sample has a low success rate. Couples in whom oligozoospermia has been identified as the principal cause of infertility do not benefit from therapeutic insemination by husband. Because of this low success rate, intrauterine insemination to pro...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1987-12-01 00:00:00
abstract：:Recent guidelines from multiple organizations stress screening initiation no earlier than the age of 21 years and increased screening intervals for women aged 21 to 29 years. Primary prevention with human papillomavirus vaccination has the potential to significantly affect the development of high-grade cervical lesion...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章
doi：10.1016/j.ogc.2013.02.007
更新日期：2013-06-01 00:00:00
abstract：:The discovery that insulin resistance has a key role in the pathophysiology of PCOS has led to a novel and promising form of therapy in the form of the insulin-sensitizing drugs. Although no extremely large trials using these drugs for this indication have been performed, more than 18 trials have specifically examined...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8545(05)70191-1
更新日期：2001-03-01 00:00:00
abstract：:Urinary incontinence and voiding dysfunction are common forms of pelvic floor dysfunction affecting women. The complex interactions between the nervous system and lower urinary tract anatomy allow for the coordinated functions of urine storage and evacuation. A thorough understanding of these components and their inte...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章
doi：10.1016/j.ogc.2009.08.012
更新日期：2009-09-01 00:00:00
abstract：:Canavan disease is a severe leukodystrophy more common among Ashkenazi Jews. The enzyme defect, apartoacylase, has been identified, and the gene cloned. Only two mutations account for over 98% of all Jewish alleles with Canavan disease. The carrier frequency among healthy Jews is 1:37-58. Carrier detection and prenata...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8545(01)00003-1
更新日期：2002-06-01 00:00:00
abstract：:It is now widely accepted that cancer of the breast is a systemic disease and that some patients will not be cured even with the most extensive local treatment. This acceptance has resulted in a more conservative approach and participation of the patient in treatment planning. A number of factors influence the definit...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1994-12-01 00:00:00
abstract：:In the 50 years since pelvic muscle exercises were introduced for the nonsurgical management of pelvic floor dysfunction related to parturition, a variety of approaches have been introduced and the scope of indications has grown. This article describes the evaluation of patients with pelvic floor complaints, discusses...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8545(05)70046-2
更新日期：1998-12-01 00:00:00
abstract：:Inherited thrombophilias present an opportunity to review population-based screening paradigms. Inherited thrombophilias are a group of complex conditions, and women who carry mutations in implicated genes have an increased risk of adverse pregnancy outcomes as well as venous thromboembolism. That asymptomatic carrier...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章
doi：10.1016/j.ogc.2010.02.018
更新日期：2010-03-01 00:00:00
abstract：:As the health care system transforms to accommodate an increased need for primary care services and more patients, new models of health care delivery are needed that can provide quality health care services efficiently. An integrated collaborative practice of certified nurse-midwives, obstetrician-gynecologists, and p...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2012.05.009
更新日期：2012-09-01 00:00:00
abstract：:An understanding of cesarean delivery for nonreassuring fetal heart rate tracing is important for several reasons. This article describes the prevalence of cesarean for nonreassuring fetal heart rate tracing and risk factors, indicates what type of fetal heart rate tracing abnormalities prompts cesarean delivery, reit...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2005.01.003
更新日期：2005-06-01 00:00:00
abstract：:Penile HPV infection and disease are very common in sexually active men, and may be manifest in many forms. Treatment of clinically detectable lesions is advisable not only to relieve symptoms but also to prevent the spread of HPV infection to new sexual partners. Treatment of subclinical disease is more controversial...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8545(05)70281-3
更新日期：1996-12-01 00:00:00
abstract：:The concept of having an in-house obstetrician (serving as an obstetrics [OB] hospitalist) available 24 hours a day, 7 days a week provides a safety net for OB events that many need immediate intervention for a successful outcome. A key precept of risk management, that of loss prevention, fits perfectly with the addit...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2015.05.008
更新日期：2015-09-01 00:00:00
abstract：:Sleep and metabolism are essential components of health. Metabolic health depends largely on individual's lifestyle. Disturbances in sleep health, such as changes in sleep patterns that are associated with menopause/reproductive aging and chronologic aging, may have metabolic health consequences. Sleep restriction and...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.ogc.2018.07.008
更新日期：2018-12-01 00:00:00
abstract：:The incidence of malignant melanoma is rising, and this may be the most frequently encountered malignancy during pregnancy. Because effective treatment of advanced or metastatic disease remains elusive, the key to adequate therapy is surveillance for early disease with prompt diagnostic work-up and treatment. Review o...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8545(05)70014-0
更新日期：1998-06-01 00:00:00
abstract：:The United States cesarean rate has risen from 5.5 per 100 deliveries in 1970 to 24.1 per 100 deliveries in 1986 according to the National Hospital Discharge Survey. Less than 10 per cent of mothers have a vaginal birth after a prior cesarean. Women spend an average of 5.0 days in the hospital for a cesarean delivery,...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章
doi：
更新日期：1988-12-01 00:00:00
abstract：:In less than two decades, hysteroscopy has evolved into a practical technique for the evaluation of the uterine cavity, with well-established indications such as evaluation of abnormal uterine bleeding and abnormal hysterograms as well as the treatment of intrauterine adhesions or the septate uterus, the removal of mi...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1988-03-01 00:00:00
abstract：:Voiding dysfunction in women results from either a failure of the bladder to contract appropriately or a failure of the urethra or bladder neck to relax during attempts at micturition. Complaints of urinary frequency and urgency most often accompany voiding dysfunction. Associated symptoms, which are not always presen...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1989-12-01 00:00:00
abstract：:If the contraindications to hysteroscopy are observed, complications should be small. The risks of fluid overload, especially in operative cases, is the most common critical problem, so that accurate recording of fluid use and collection are essential. The inexperienced, unsupervised surgeon is most likely to encounte...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1995-09-01 00:00:00
abstract：:It appears that both laparoscopic and laparotomy approaches to myomectomy are viable surgical procedures. Both surgeries can be performed with minimal risk. Pregnancy rates after either procedure are high. The advantage of laparotomy over laparoscopy is that it is technically easier. On the other hand, laparoscopy ena...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8545(00)80031-5
更新日期：2000-06-01 00:00:00
abstract：:The surgical procedures used for the treatment of chronic pelvic pain, their indications, and success rates are reviewed. A thorough preoperative evaluation is presented that will enable the physician to detect patients at high risk for surgical failure and those who will be more appropriately managed with nonsurgical...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1993-12-01 00:00:00
abstract：:The use of laparoscopic ultrasound probes has been shown to improve outcomes and facilitate surgery for hepatobiliary and pancreatic cancers. It is a useful, inexpensive, and safe imaging technique that should also supplement operative laparoscopy for gynecologic indications. These techniques are new, and their use in...
journal_title：Obstetrics and gynecology clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8545(05)70058-9
更新日期：1999-03-01 00:00:00
