Expression of intercellular adhesion molecule-1 on rat cardiac myocytes by monocyte chemoattractant protein-1.

abstract：:Regional distribution of myocardial blood flow (MBF) was examined in eight normal and nine pulmonary artery banded (PAB) pigs before and during pacing induced tachycardia (heart rates: 175, 225 and 275 beats X min-1) as well as during iv adenosine infusion (1.5 mg X kg-1 X min-1; maximal coronary vasodilatation) using...

journal_title：Cardiovascular research

authors： Manohar M

更新日期：1985-02-01 00:00:00

abstract：:Zero drift may be a cause of imprecision when micromanometer tipped catheters are used for intravascular pressure measurement over long periods of time. Drift of only a few mm Hg may represent a significant error when accurate recording of low vascular pressures is required. To overcome this problem a micromanometer t...

journal_title：Cardiovascular research

authors： Gibbs JS,Cunningham D,Sparrow J,Poole-Wilson PA,Fox KM

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands have been shown to ameliorate a variety of inflammatory conditions. The present study tested the hypothesis that PPAR-gamma ligands reduce experimental autoimmune myocarditis (EAM) associated with inhibition of the expansion and activation...

journal_title：Cardiovascular research

authors： Yuan Z,Liu Y,Liu Y,Zhang J,Kishimoto C,Wang Y,Ma A,Liu Z

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:This study aimed to examine the effects of adenovirus-mediated expression of p35, a baculovirus gene, on apoptosis induced by hypoxia/reoxygenation (H/R) in cardiomyocytes. METHODS:Neonatal rat cardiomyocytes were infected with recombinant adenoviral vectors expressing p35 (Ad2/CMVp35) or no transgene (Ad2/C...

journal_title：Cardiovascular research

authors： Date T,Belanger AJ,Mochizuki S,Sullivan JA,Liu LX,Scaria A,Cheng SH,Gregory RJ,Jiang C

更新日期：2002-08-01 00:00:00

abstract：AIMS:The discovery of a specific prorenin receptor (PRR) suggests a biological function of prorenin that is independent of angiotensin I production. In the present study, we investigated the role of PRR on smooth muscle cell (SMC) migration. METHODS AND RESULTS:PRR was expressed in human mammary arteries and in cultur...

journal_title：Cardiovascular research

authors： Greco CM,Camera M,Facchinetti L,Brambilla M,Pellegrino S,Gelmi ML,Tremoli E,Corsini A,Ferri N

更新日期：2012-08-01 00:00:00

abstract：:By measuring the coronary sinus blood flow using the thermodilution technique the influence of "thermodilution catheter" withdrawal from the great cardiac vein to the ostium of the coronary sinus was investigated in 41 patients. In addition, the influence of normal and forced respiration on coronary sinus blood flow w...

journal_title：Cardiovascular research

authors： Bagger JP

更新日期：1985-01-01 00:00:00

abstract：:Major advances in molecular biology over the past decade have increased our understanding of how genes are expressed and regulated in mammalian cells in vivo. This knowledge has been translated to investigations of the molecular and cellular biology of the cardiovascular system. Gene transfer, the introduction of a re...

journal_title：Cardiovascular research

authors： Nabel EG,Pompili VJ,Plautz GE,Nabel GJ

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVES:Responses to EDHF are usually characterised in the presence of nitric oxide synthase (NOS) and cyclooxygenase (COX) inhibitors. The contribution of NO to endothelium-dependent relaxation in the presence of NOS inhibitors was assessed using NO scavengers with the objective of testing (i) whether any residual ...

journal_title：Cardiovascular research

authors： Chauhan S,Rahman A,Nilsson H,Clapp L,MacAllister R,Ahluwalia A

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES:The A10 cell line was derived from the thoracic aorta of embryonic rat and is a commonly used model of vascular smooth muscle cells (VSMC). Despite its wide use this cell line has not been well characterized. This is especially important in light of recent evidence of phenotypically distinct cell populations...

journal_title：Cardiovascular research

authors： Rao RS,Miano JM,Olson EN,Seidel CL

更新日期：1997-10-01 00:00:00

abstract：AIMS:Vascular calcification often occurs with advancing age, atherosclerosis, and metabolic disorders such as diabetes mellitus and end-stage renal disease. Vascular calcification is associated with cardiovascular events and increased mortality. Nitric oxide (NO) is crucial for maintaining vascular function, but little...

journal_title：Cardiovascular research

authors： Kanno Y,Into T,Lowenstein CJ,Matsushita K

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:The aim was to examine the ventricular expression of brain natriuretic peptide (BNP) in the transplanted human heart. METHODS:Serial right ventricular biopsies (n = 68) and plasma samples (n = 68) were obtained for measurement of BNP and atrial natriuretic peptide (ANP) from 14 orthotopic cardiac transplant ...

journal_title：Cardiovascular research

authors： Ationu A,Burch M,Singer D,Littleton P,Carter N

更新日期：1993-02-01 00:00:00

abstract：AIMS:The goal of this study was to determine whether the A1 adenosine receptor (AR) plays a role in atherosclerosis development and to explore its potential mechanisms. METHODS AND RESULTS:Double knockout (DKO) mice, deficient in the genes encoding A1 AR and apolipoprotein E (apoE), demonstrated reduced atheroscleroti...

journal_title：Cardiovascular research

authors： Teng B,Smith JD,Rosenfeld ME,Robinet P,Davis ME,Morrison RR,Mustafa SJ

更新日期：2014-04-01 00:00:00

abstract：Aims:MicroRNAs (miRNAs) have been implicated in the pathogenesis of pulmonary hypertension (PH), a multifactorial and progressive condition associated with an increased afterload of the right ventricle leading to heart failure and death. The main aim of this study was to correlate the levels of miR-424(322) with the se...

journal_title：Cardiovascular research

authors： Baptista R,Marques C,Catarino S,Enguita FJ,Costa MC,Matafome P,Zuzarte M,Castro G,Reis A,Monteiro P,Pêgo M,Pereira P,Girão H

更新日期：2018-01-01 00:00:00

abstract：AIMS:This study aimed at characterizing expression and the functional role of the Gjb6 gene, encoding for connexin 30 (Cx30) protein, in the adult mouse heart. METHODS AND RESULTS:The expression of the Gjb6 gene in the mouse heart was investigated by RT-PCR and sequencing of amplified cDNA fragments. The sites of Gjb6...

journal_title：Cardiovascular research

authors： Gros D,Théveniau-Ruissy M,Bernard M,Calmels T,Kober F,Söhl G,Willecke K,Nargeot J,Jongsma HJ,Mangoni ME

更新日期：2010-01-01 00:00:00

abstract：:Gender has an important influence on blood pressure, with premenopausal women having a lower arterial blood pressure than age-matched men. Compared with premenopausal women, postmenopausal women have higher blood pressures, suggesting that ovarian hormones may modulate blood pressure. However, whether sex hormones are...

journal_title：Cardiovascular research

authors： Dubey RK,Oparil S,Imthurn B,Jackson EK

更新日期：2002-02-15 00:00:00

abstract：OBJECTIVE:Both superoxide dismutase (SOD) and nitric oxide synthase (NOS) have been implicated in delayed preconditioning (DP) to ischemia/reperfusion (I/R) in the heart. We used isolated cardiac myocytes to test the hypothesis that SOD and NOS may interact in the development of DP. METHODS:Mouse neonatal cardiac myoc...

journal_title：Cardiovascular research

authors： Rui T,Cepinskas G,Feng Q,Kvietys PR

更新日期：2003-10-01 00:00:00

abstract：AIMS:Antihypertensive drugs are included in the medical therapy of vascular Ehlers-Danlos syndrome (vEDS). The β-blocker celiprolol has been suggested to prevent arterial damage in vEDS, but the underlying mechanism remains unclear. It is also unknown whether the widely used angiotensin II receptor type 1 antagonist lo...

journal_title：Cardiovascular research

authors： Dubacher N,Münger J,Gorosabel MC,Crabb J,Ksiazek AA,Caspar SM,Bakker ENTP,van Bavel E,Ziegler U,Carrel T,Steinmann B,Zeisberger S,Meienberg J,Matyas G

更新日期：2020-02-01 00:00:00

abstract：AIMS:Dilated cardiomyopathy (DCM) is characterized by ventricular dilation associated with systolic dysfunction, which could be caused by mutations in lamina/C gene (LMNA). LMNA-linked DCM is severe in males in both human patients and a knock-in mouse model carrying a homozygous p.H222P mutation (LmnaH222P/H222P). The ...

journal_title：Cardiovascular research

authors： Arimura T,Onoue K,Takahashi-Tanaka Y,Ishikawa T,Kuwahara M,Setou M,Shigenobu S,Yamaguchi K,Bertrand AT,Machida N,Takayama K,Fukusato M,Tanaka R,Somekawa S,Nakano T,Yamane Y,Kuba K,Imai Y,Saito Y,Bonne G,Kimura A

更新日期：2013-08-01 00:00:00

abstract：:Nitric oxide (NO) is a highly reactive, free radical signalling molecule that is constitutively released in cardiomyocytes by both the endothelial and neuronal isoforms of nitric oxide synthase (eNOS and nNOS, respectively). There are increasing data indicating that NO modulates various proteins involved in excitation...

journal_title：Cardiovascular research

authors： Lim G,Venetucci L,Eisner DA,Casadei B

更新日期：2008-01-15 00:00:00

abstract：OBJECTIVES:Coronary microvascular endothelial cells (CMVEs) can modulate the contractile performance of the adjacent myocardium by the release of agents such as nitric oxide (NO). Most previous studies using CMVEs have been done in situ, in the intact organ. We set out to study possible differences in NO synthase (NOS)...

journal_title：Cardiovascular research

authors： Lang D,Bell JP,Bayraktutan U,Small GR,Shah AM,Lewis MJ

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVES:I(Ks), the slow component of the delayed rectifier potassium current, underlies a strong beta-adrenergic regulation in the heart. Catecholamines, like isoproterenol, induce a strong increase in I(Ks). Recent work has pointed to an opposing biological effect of beta(1)- and beta(3)-adrenoceptors in the heart....

journal_title：Cardiovascular research

authors： Bosch RF,Schneck AC,Kiehn J,Zhang W,Hambrock A,Eigenberger BW,Rüb N,Gogel J,Mewis C,Seipel L,Kühlkamp V

更新日期：2002-12-01 00:00:00

abstract：AIMS:Crosstalk between cardiomyocytes and fibroblasts in physiological conditions and during disease remains poorly defined. Previous studies have shown that fibroblasts and myocytes interact via paracrine communication, but several experimental confounding factors, including the use of immature myocytes and the induct...

journal_title：Cardiovascular research

authors： Cartledge JE,Kane C,Dias P,Tesfom M,Clarke L,Mckee B,Al Ayoubi S,Chester A,Yacoub MH,Camelliti P,Terracciano CM

更新日期：2015-03-01 00:00:00

abstract：:Numerous epidemiological studies documented an inverse relationship between plasma high-density lipoprotein (HDL) cholesterol levels and the extent of atherosclerotic disease. However, clinical interventions targeting HDL cholesterol failed to show clinical benefits with respect to cardiovascular risk reduction, sugge...

journal_title：Cardiovascular research

authors： Potì F,Simoni M,Nofer JR

更新日期：2014-08-01 00:00:00

abstract：:To examine how end systole differs from end ejection and also whether the slope of the end systolic pressure-volume relation can be approximated to that of the end ejection pressure-volume relation, nine isolated, perfused, paced canine hearts ejecting into a hydraulic loading system that simulated the aortic input im...

journal_title：Cardiovascular research

authors： Nishioka O,Maruyama Y,Ashikawa K,Isoyama S,Satoh S,Suzuki H,Watanabe J,Watanabe H,Shimizu Y,Ino-Oka E

更新日期：1987-02-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most common tachyarrhythmia in clinical practice. Over decades of research, a vast amount of knowledge has been gathered about the causes and consequences of AF related to cellular electrophysiology and features of the tissue structure that influence the propagation of fibrillation wave...

journal_title：Cardiovascular research

authors： Opacic D,van Bragt KA,Nasrallah HM,Schotten U,Verheule S

更新日期：2016-04-01 00:00:00

abstract：:To determine the effect of an anteroseptal myocardial infarction on right ventricular systolic and diastolic function, we studied 12 pigs before and 1 h after left anterior descending coronary artery occlusion. Total arterial occlusion was achieved by the percutaneous, transcatheter placement of a 1 mm Teflon plug int...

journal_title：Cardiovascular research

authors： Lancaster LD,Kern KB,Morrison DA,Olajos M,Goldman S

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:Cholinergic vasodilation has been thought to play little if any role in the regulation of blood pressure in humans. Autonomic denervation potentiates the vasoconstriction evoked by nitric oxide synthase inhibition in humans, but the mechanism is unclear. We hypothesized that this may be related to loss of neu...

journal_title：Cardiovascular research

authors： Lepori M,Sartori C,Duplain H,Nicod P,Scherrer U

更新日期：2001-09-01 00:00:00

abstract：:Ventricular function curves relating stroke work and left ventricular end-diastolic pressure were generated in awake dogs during increases in preload produced by infusion of fluid and during increases in afterload produced by administration of phenylephrine. The ventricular function curves produced by preloading were ...

journal_title：Cardiovascular research

authors： Rosenfeldt FL,Cobb FR,Bache RJ,Sabiston DC Jr

更新日期：1979-07-01 00:00:00

abstract：OBJECTIVE:The purpose was to investigate the influence of the 38-amino-acid neuropeptide, pituitary adenylate cyclase activating polypeptide (PACAP38), on contractile function and coronary vascular tone in neonatal hearts. METHODS:Isolated, paced (150 bpm), isovolumically-beating, piglet hearts (n = 19) underwent retr...

journal_title：Cardiovascular research

authors： Ascuitto RJ,Ross-Ascuitto NT,Waddell AE,Kadowitz PJ

更新日期：1996-02-01 00:00:00

abstract：:The isolated perfused heart has been used increasingly during the last decade as a model for identifying actions of drugs on ventricular fibrillation (VF) induced by myocardial ischaemia. In addition, it has been used to explore the mechanisms responsible for the initiation and maintenance of VF, the concept of endoge...

journal_title：Cardiovascular research

authors： Curtis MJ

更新日期：1998-07-01 00:00:00