Mediator-specific therapies for the systemic inflammatory response syndrome, sepsis, severe sepsis, and septic shock: present and future approaches.

Abstract:

:Despite recent advances in critical care and cardiopulmonary support, mortality from septic shock and its complications remains high. Effective therapies are needed to halt the progression of SIRS and the septic cascade prior to development of shock and organ ischemia/dysfunction. Such therapies are directed at prevention of infection/endotoxemia and modulation of mediators. These therapies are the focus of this article.

authors

Hazinski MF

subject

Has Abstract

pub_date

1994-06-01 00:00:00

pages

309-19

issue

2

eissn

0899-5885

issn

1558-3481

journal_volume

6

pub_type

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