Abstract:
:In a two-centre study, intrasellar pituitary tissue pressure was measured at transsphenoidal surgery in 107 patients with pituitary adenomas or intrasellar cysts. 'Normal' ISP in patients under anaesthesia with small microadenomas (< 5 mm diameter) or a partial empty sella was 12 +/- 3 mmHg. Raised ISP (> 15 mmHg) was found in 75% of cases. The highest pressures were recorded in tumours with parasellar invasion (30 +/- 2; p < 0.01) irrespective of size and extension in other directions. In non-invasive lesions there was no correlation between the level of raised ISP and tumour size. Hypopituitarism and stalk compression syndrome were both associated with higher ISP than patients with normal pituitary function.
journal_name
Br J Neurosurgjournal_title
British journal of neurosurgeryauthors
Lees PD,Fahlbusch R,Zrinzo A,Pickard JDdoi
10.3109/02688699409029619subject
Has Abstractpub_date
1994-01-01 00:00:00pages
313-8issue
3eissn
0268-8697issn
1360-046Xjournal_volume
8pub_type
杂志文章abstract::Objective: Deep brain stimulation of the subthalamic nucleus (STN-DBS) is a useful therapy to improve motor functions and reduce dependence on medication in patients with Parkinson's disease (PD). The purpose of the study is to assess the long-term clinical outcomes of STN-DBS and to determine the optimal placement of...
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