QTc interval prolongation during infusion with dipyridamole or adenosine.

Abstract:

:The aim of our study was to discover whether there was a relationship between the QTc interval prolongation on the standard 12-lead electrocardiogram (ECG) and provoked myocardial ischemia. Since the increase of adenosine plasma levels, obtained either with adenosine or dipyridamole (an adenosine reuptake inhibitor) infusion, has been used to test the coronary artery reserve in patients affected by coronary artery disease, the QTc interval modifications during dipyridamole or adenosine echocardiographic stress test were evaluated. Twenty-five patients admitted to our Institute for evaluation of chest pain of suspected myocardial origin underwent an echocardiographic dipyridamole stress test (0.84 mg/kg over 10 min) after discontinuation of antianginal treatment. Of these patients, 10 underwent an echocardiographic adenosine stress test (scalar doses of 50, 75, 100, 140 micrograms/kg/min) after 48-72 h. The Bazett formula was used to evaluate the QTc interval. After dipyridamole and adenosine administration, a significant prolongation of the QTc interval was observed only in those patients who had positive test results. Our data suggested that QTc interval prolongation during pharmacological stress tests might be considered a marker of myocardial ischemia.

journal_name

Int J Cardiol

authors

Guideri F,Ferber D,Galgano G,Isidori S,Blardi P,Pasini FL,Di Perri T

doi

10.1016/0167-5273(94)02209-2

subject

Has Abstract

pub_date

1995-01-27 00:00:00

pages

67-73

issue

1

eissn

0167-5273

issn

1874-1754

pii

0167527394022092

journal_volume

48

pub_type

杂志文章
  • Cancer anorexia: a model for the understanding and treatment of secondary anorexia.

    abstract::Under normal conditions, food intake is controlled in the hypothalamus by: (i) transducing metabolic/sensorial inputs arising from the periphery into neuronal response; (ii) integrating the information originating from different tissues; and (iii) triggering the appropriate feeding responses. Thus, the anorexia associ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0167-5273(02)00234-6

    authors: Rossi Fanelli F,Laviano A

    更新日期:2002-09-01 00:00:00

  • CCN2/CTGF attenuates myocardial hypertrophy and cardiac dysfunction upon chronic pressure-overload.

    abstract:BACKGROUND:Myocardial CCN2/CTGF (connective tissue growth factor) is strongly induced in heart failure (HF) and acts as a cardioprotective factor in ischemia/reperfusion injury. However, its functional role in myocardial hypertrophy remains unresolved. METHODS AND RESULTS:Transgenic mice with cardiac-restricted overex...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2013.01.165

    authors: Gravning J,Ahmed MS,von Lueder TG,Edvardsen T,Attramadal H

    更新日期:2013-10-03 00:00:00

  • Alarming trends in ideal cardiovascular health among children and adolescents in Beijing, China, 2004 to 2014.

    abstract:BACKGROUND:The American Heart Association's 2020 Strategic Goals have defined a new concept of cardiovascular health for adults and children, emphasizing the importance of primordial prevention of cardiovascular diseases. However, detailed data on the trends of ideal cardiovascular health in Chinese children and adoles...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2016.12.027

    authors: Dong H,Yan Y,Liu J,Zhao X,Cheng H,Hou D,Huang G,Li S,Wang Y,Mi J

    更新日期:2017-03-15 00:00:00

  • Heart rate turbulence for predicting new-onset atrial fibrillation in patients undergoing coronary artery bypass grafting.

    abstract:BACKGROUND:Cardiac autonomic dysfunction reportedly contributes to the AF triggering and maintenance. Heart rate turbulence (HRT) is a promising noninvasive measure of cardiac autonomic function. We investigated whether ambulatory ECG-based HRT measurement could predict in-hospital new-onset atrial fibrillation (AF) af...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2014.04.130

    authors: Park SJ,On YK,Kim JS,Jeong DS,Kim WS,Lee YT

    更新日期:2014-07-01 00:00:00

  • Effects of acetylstrophanthidin on baroreflex sensitivity in patients with acute myocardial infarction.

    abstract::We evaluated the effects of acetylstrophanthidin on baroreflex sensitivity in patients soon after an acute myocardial infarction. Baroreflex control of heart rate is frequently depressed after acute myocardial infarction and few data are available as to the effects of pharmacological intervention on this parameter. Th...

    journal_title:International journal of cardiology

    pub_type: 临床试验,杂志文章

    doi:10.1016/0167-5273(93)90131-y

    authors: Bonaduce D,Petretta M,Morgano G,Bianchi V,Themistoclakis S,Rotondi F,Valva G,Carpinelli A

    更新日期:1993-08-01 00:00:00

  • The prognostic utility of dihomo-gamma-linolenic acid (DGLA) in patients with acute coronary heart disease.

    abstract:BACKGROUND:We previously investigated the prognostic utility of red blood cell (RBC) n-3 fatty acids (FAs) in survivors of an acute myocardial syndrome (ACS) but found no relationship with all-cause mortality and cardiac death or MI after two years. Here we extend our follow-up to 7years, focusing on the potential pred...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2017.09.202

    authors: Nilsen DWT,Aarsetoey H,Pönitz V,Brugger-Andersen T,Staines H,Harris WS,Grundt H

    更新日期:2017-12-15 00:00:00

  • Association of lipid profile with echocardiographic Wilkins score in patients with moderate to severe mitral stenosis: possible impact on prognosis.

    abstract:BACKGROUND:Association of valvular heart disease and lipid profile might be important as in the case of aortic stenosis. However, it has not been so far considered in detail the probable association of other valvular diseases, particularly of mitral stenosis (MS) with lipid profile. In our study, we aimed to search pos...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2005.10.003

    authors: Yilmaz MB,Demirkan B,Caldir V,Guray Y,Guray U,Sasmaz H,Korkmaz S

    更新日期:2006-10-10 00:00:00

  • Criss-cross heart with intact ventricular septum.

    abstract::We report a case of a criss-cross heart in a 6-month-old male child with echocardiographic and angiocardiographic findings of concordant atrioventricular and discordant ventriculoarterial connexions and an intact ventricular septum. This entity has been described with a ventricular septal defect as part of its own ana...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(90)90102-b

    authors: Fontes VF,de Souza JA,Pontes Jùnior SC

    更新日期:1990-03-01 00:00:00

  • 5-year serial follow-up of clinical condition and ventricular function in patients after repair of tetralogy of Fallot.

    abstract:OBJECTIVE:To study the changes over time in biventricular size and function, and clinical parameters in patients after repair of tetralogy of Fallot (TOF) without subsequent pulmonary valve replacement (PVR). METHODS:We prospectively included 78 non-PVR patients (age 20(6-60)years at baseline), who were studied twice ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ijcard.2013.10.013

    authors: Luijnenburg SE,Helbing WA,Moelker A,Kroft LJ,Groenink M,Roos-Hesselink JW,de Rijke YB,Hazekamp MG,Bogers AJ,Vliegen HW,Mulder BJ

    更新日期:2013-11-30 00:00:00

  • Effects of amlodipine and lacidipine on heart rate variability in hypertensive patients with stable angina pectoris and isolated left ventricular diastolic dysfunction.

    abstract:OBJECTIVE:To estimate the influence of therapy with amlodipine (A) or lacidipine (L) on heart rate variability (HRV) time and frequency domain parameters in hypertensive patients with stable angina pectoris and isolated left ventricular diastolic dysfunction. METHODS:After a 1-week washout period, the patients were ra...

    journal_title:International journal of cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.ijcard.2004.03.040

    authors: Zaliūnas R,Brazdzionyte J,Zabiela V,Jurkevicius R

    更新日期:2005-06-08 00:00:00

  • Hemodynamic, not ventilatory, inefficiency is associated with high VE/VCO2 slope in repaired, noncyanotic congenital heart disease.

    abstract:BACKGROUND:A high slope of the ventilation vs. carbon dioxide relationship (VE/VCO₂ slope) during incremental exercise has been reported in several congenital heart disease (CHD) types, but it is not clear whether the main cause of high VE/VCO₂ slope is excessive ventilation or reduced perfusion. METHODS:We studied 16...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2015.04.285

    authors: Mezzani A,Giordano A,Moussa NB,Micheletti A,Negura D,Saracino A,Canal E,Giannuzzi P,Chessa M,Carminati M

    更新日期:2015-07-15 00:00:00

  • Vasculoprotective properties of enhanced external counterpulsation for coronary artery disease: beyond the hemodynamics.

    abstract::A growing pool of evidence has shown that enhanced external counterpulsation (EECP) is a non-invasive, safe, low-cost, and highly beneficial therapy for patients with coronary artery disease. However, the exact mechanisms of benefit exerted by EECP therapy remain only partially understood. The favorable hemodynamic ef...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ijcard.2012.04.003

    authors: Yang DY,Wu GF

    更新日期:2013-06-05 00:00:00

  • Transmural distribution of myocardial blood perfusion and phasic coronary blood flow pattern in a canine model of acute ischemia.

    abstract:BACKGROUND:Although several investigators have analyzed coronary artery blood flow under various conditions, almost all these studies have measured only some branches of the left anterior descending (LAD), left circumflex (LCX), or right coronary (RCA) artery. METHODS:In a canine model of acute ischemia (n = 5), we si...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2005.03.056

    authors: Ootaki Y,Kamohara K,Schenk S,Kopcak MW Jr,Dessoffy R,Schoenhagen P,Fukamachi K

    更新日期:2006-03-08 00:00:00

  • Rates and determinants of progressive aortic valve dysfunction in aortic coarctation.

    abstract:PURPOSE:Aortic valve dysfunction is common in coarctation patients(CoA). Bicuspid aortic valve (BAV) in CoA is associated with aortic valve stenosis (AS), aortic valve regurgitation (AR), and ascending aortic dilatation. The aim of this study was to evaluate the progression of and predictors for aortic valve dysfunctio...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2012.07.028

    authors: Luijendijk P,Stevens AW,de Bruin-Bon RH,Boekholdt SM,Vriend JW,Vliegen HW,Bouma BJ,Mulder BJ

    更新日期:2013-09-10 00:00:00

  • Use of lipid lowering drugs in patients at very high risk of cardiovascular events: An analysis on nearly 3,000,000 Italian subjects of the ARNO Observatory.

    abstract:AIM:To assess clinical characteristics, use of resources and costs of patients at very high risk (VHR) of cardiovascular (CV) events. Further, to assess how VHR patients are treated with statins (rate of prescription, dosages, adherence). METHODS AND RESULTS:A record linkage analysis was carried out of patient demogra...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ijcard.2017.02.108

    authors: Maggioni AP,Calabria S,Rossi E,Martini N,on the behalf of the ARNO Observatory.

    更新日期:2017-11-01 00:00:00

  • Clinical assessment of elastic properties of large coronary arteries: pressure-diameter relationship and dynamic incremental elastic modulus.

    abstract::Vascular elastic properties in vivo (dynamic incremental elastic modulus [Ep(dyn)]) of large coronary arteries were assessed from the pressure-diameter relationships of the large coronary arteries in 46 patients with suspected ischemic heart disease. Ep(dyn) represents the vascular stiffness primarily determined by th...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(86)90077-x

    authors: Shimazu T,Hori M,Mishima M,Kitabatake A,Kodama K,Nanto S,Inoue M

    更新日期:1986-10-01 00:00:00

  • Stroke risk reduction with oral anticoagulation using CHA2DS2-VASc in a Japanese AF population: A modeling analysis.

    abstract:BACKGROUND:Current clinical guidelines recommend that risk stratification for ischaemic stroke in patients with nonvalvular AF (NVAF) should be performed using the CHA2DS2-VASc score (Congestive heart failure, Hypertension, Age≥ 75years [double], Diabetes mellitus, previous thromboembolism [double], Vascular disease, A...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2014.11.196

    authors: Senoo K,Lane DA,Lip GY

    更新日期:2015-02-15 00:00:00

  • Changes of autonomic tone before the onset of paroxysmal atrial fibrillation.

    abstract::The relationship between autonomic nerve system and the onset of paroxysmal atrial fibrillation (PAF) is still controversial. Furthermore, no prior studies have compared heart rate variability (HRV) between PAF patients with (organic) or without (idiopathic) underlying cardiac diseases. The purpose of this study was t...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/s0167-5273(98)00241-1

    authors: Huang JL,Wen ZC,Lee WL,Chang MS,Chen SA

    更新日期:1998-10-30 00:00:00

  • Isolated episode of exercise-related ventricular fibrillation in a healthy athlete.

    abstract::A 19-year-old man had a documented ventricular fibrillation during a football match. He was a top-level athlete, and after successful resuscitation, he was extensively studied. Electrolytic disturbances, long QT syndrome and nervous mechanisms were all ruled out. Right and left ventriculography, coronary angiograms, e...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(89)90053-3

    authors: Buja G,Meneghello MP,Bellotto F

    更新日期:1989-07-01 00:00:00

  • MADIT II, the Multi-center Autonomic Defibrillator Implantation Trial II stopped early for mortality reduction, has ICD therapy earned its evidence-based credentials?

    abstract::In a press conference on Nov. 20, 2001 it was announced that the Multi-center Autonomic Defibrillator Implantation Trial II (MADIT II) was stopped early because of a 30% reduction in mortality in patients randomised to receive an implantable defibrillator device. The 4 year multi-centre trial of 1200 patients was term...

    journal_title:International journal of cardiology

    pub_type: 社论

    doi:

    authors: Coats AJ

    更新日期:2002-01-01 00:00:00

  • Clinical profile of concealed form of arrhythmogenic right ventricular cardiomyopathy presenting with apparently idiopathic ventricular arrhythmias.

    abstract::In 24 subjects presenting with apparently idiopathic ventricular arrhythmias, a final diagnosis of arrhythmogenic right ventricular cardiomyopathy was formulated following global evaluation of the clinical, cross-sectional echocardiography and angiographic findings, and the observation of myocardial atrophy with fibro...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(92)90177-5

    authors: Nava A,Thiene G,Canciani B,Martini B,Daliento L,Buja G,Fasoli G

    更新日期:1992-05-01 00:00:00

  • Comparison of the Tei index with invasive measurements of right ventricular function.

    abstract::The Doppler-derived Tei index has been reported to be clinically useful in assessing global right ventricular function. It could increase in response to combinations of increased pulmonary artery pressure and/or ventricular dysfunction. We compared the Tei index with invasive measurements of right ventricular function...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2005.10.012

    authors: Grignola JC,Ginés F,Guzzo D

    更新日期:2006-10-26 00:00:00

  • Practices in management of cancer treatment-related cardiovascular toxicity: A cardio-oncology survey.

    abstract:BACKGROUND:Cardiovascular toxicity has become a challenging issue during cancer therapy. Nonetheless, there is a lack of consensual guidelines for their management. We aimed to determine the current practices of oncologists regarding cardiovascular toxicity related to anthracyclines, trastuzumab and angiogenic inhibito...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2017.02.154

    authors: Jovenaux L,Cautela J,Resseguier N,Pibarot M,Taouqi M,Orabona M,Pinto J,Peyrol M,Barraud J,Laine M,Bonello L,Paganelli F,Barlesi F,Thuny F

    更新日期:2017-08-15 00:00:00

  • Catheter-induced straightening of external iliac tortuosity: a cause of pseudostenosis to be borne in mind.

    abstract::Reversible vascular obstructive lesions, i.e. pseudostenoses, may pose significant threats to interventional cardiologists as they can be mistaken for obstructive lesions and prompt inappropriate revascularization procedures. We hereby report for the first time in the literature a case of external iliac artery pseudos...

    journal_title:International journal of cardiology

    pub_type: 信件

    doi:10.1016/j.ijcard.2004.02.007

    authors: Trani C,Biondi-Zoccai GG,Burzotta F,Todaro D,Romagnoli E,Abbate A,Ramazzotti V,Belloni F,Mazzari MA,Mongiardo R,Crea F

    更新日期:2005-05-25 00:00:00

  • Localization of CD8 T cell epitope within cardiac myosin heavy chain-α334-352 that induces autoimmune myocarditis in A/J mice.

    abstract:BACKGROUND:Cardiac myosin heavy chain-α (Myhc), an intracellular protein expressed in the cardiomyocytes, has been identified as a major autoantigen in cardiac autoimmunity. In our studies with Myhc334-352-induced experimental autoimmune myocarditis in A/J mice (H-2a), we discovered that Myhc334-352, supposedly a CD4 T...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2015.09.016

    authors: Massilamany C,Gangaplara A,Basavalingappa RH,Rajasekaran RA,Khalilzad-Sharghi V,Han Z,Othman S,Steffen D,Reddy J

    更新日期:2016-01-01 00:00:00

  • Isolated congenital left ventricular diverticulum in an elderly patient that was identified because of an incidental finding during a complete medical checkup.

    abstract::Congenital left ventricular diverticulum is a rare cardiac malformation in an elderly patient. It frequently is associated with other cardiac or non-cardiac congenital malformations. We present an asymptomatic elderly patient, evaluated because of an incidental finding of a left ventricular anatomic change on chest co...

    journal_title:International journal of cardiology

    pub_type: 信件

    doi:10.1016/j.ijcard.2007.04.106

    authors: Sakabe K,Fukuda N,Fukuda Y,Wakayama K,Nada T,Morishita S,Shinohara H,Tamura Y

    更新日期:2008-04-10 00:00:00

  • Impact of histopathological changes in ascending aortic diseases.

    abstract:AIMS:To better understand relationship between histological medial degenerative changes (MDC), pathological status [thoracic aorta aneurysm (TAA), thoracic aorta dissection (TAD), bicuspid aortic valve (BAV), and non-BAV] and aortic size at imaging. METHODS AND RESULTS:We collected 496 ascending aorta surgical specime...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2020.04.011

    authors: Amemiya K,Mousseaux E,Ishibashi-Ueda H,Achouh P,Ochiai M,Bruneval P

    更新日期:2020-07-15 00:00:00

  • Supraventricular tachycardia promotes release of troponin I in patients with normal coronary arteries.

    abstract:BACKGROUND:Troponin I and T are sensitive markers of myocardial injury. The presence of elevated troponin often prompts further investigation with coronary angiography. METHODS:We present a series of patients presenting to our unit with raised troponin I and supraventricular tachycardia (SVT) that prompted coronary an...

    journal_title:International journal of cardiology

    pub_type: 信件

    doi:10.1016/j.ijcard.2004.05.076

    authors: Redfearn DP,Ratib K,Marshall HJ,Griffith MJ

    更新日期:2005-07-20 00:00:00

  • Electromechanical delay by speckle-tracking echocardiography: A novel tool to distinguish between Brugada syndrome and isolated right bundle branch block.

    abstract:BACKGROUND:The electrocardiographic (ECG) definition of Brugada syndrome (BS) can be challenging because benign ECG abnormalities, such as right bundle branch block (RBBB), may mimic pathological ECG characteristics of BrS. However, although myocardial delay and deformation can be quantified by advanced imaging, it has...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2020.06.029

    authors: D'Ascenzi F,Sanz-De La Garza M,Anselmi F,Nunno L,Arbelo E,Jordà P,Marzotti T,Aprile F,Piu P,Natali BM,Brugada J,Sitges M,Mondillo S

    更新日期:2020-12-01 00:00:00

  • Biventricular pacemaker implantation in a patient with isolated noncompaction of the right ventricular myocardium.

    abstract::Isolated noncompaction of the ventricular myocardium is an unclassified cardiomyopathy and is thought to be due to arrest of myocardial morphogenesis. Fetal arrhythmias may occur in approximately half of the patients and account for the death in this disorder. We describe a patient with isolated noncompaction of the r...

    journal_title:International journal of cardiology

    pub_type: 信件

    doi:10.1016/j.ijcard.2007.07.037

    authors: Ying ZQ,Ma J,Chen S,Xu G,Chen MY,You XD

    更新日期:2008-12-17 00:00:00