QTc interval prolongation during infusion with dipyridamole or adenosine.

Abstract:

:The aim of our study was to discover whether there was a relationship between the QTc interval prolongation on the standard 12-lead electrocardiogram (ECG) and provoked myocardial ischemia. Since the increase of adenosine plasma levels, obtained either with adenosine or dipyridamole (an adenosine reuptake inhibitor) infusion, has been used to test the coronary artery reserve in patients affected by coronary artery disease, the QTc interval modifications during dipyridamole or adenosine echocardiographic stress test were evaluated. Twenty-five patients admitted to our Institute for evaluation of chest pain of suspected myocardial origin underwent an echocardiographic dipyridamole stress test (0.84 mg/kg over 10 min) after discontinuation of antianginal treatment. Of these patients, 10 underwent an echocardiographic adenosine stress test (scalar doses of 50, 75, 100, 140 micrograms/kg/min) after 48-72 h. The Bazett formula was used to evaluate the QTc interval. After dipyridamole and adenosine administration, a significant prolongation of the QTc interval was observed only in those patients who had positive test results. Our data suggested that QTc interval prolongation during pharmacological stress tests might be considered a marker of myocardial ischemia.

journal_name

Int J Cardiol

authors

Guideri F,Ferber D,Galgano G,Isidori S,Blardi P,Pasini FL,Di Perri T

doi

10.1016/0167-5273(94)02209-2

subject

Has Abstract

pub_date

1995-01-27 00:00:00

pages

67-73

issue

1

eissn

0167-5273

issn

1874-1754

pii

0167527394022092

journal_volume

48

pub_type

杂志文章
  • Thrombolytic and antithrombotic treatment in myocardial infarction: main achievements and future perspectives.

    abstract::Several trials enrolling thousands of patients have demonstrated the beneficial effect of thrombolytic therapy on survival in patients with acute myocardial infarction. Three large trials have compared the effect of different thrombolytic agents on mortality from myocardial infarction: GISSI-2/International trial, ISI...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/0167-5273(95)97995-x

    authors: Agnelli G

    更新日期:1995-08-01 00:00:00

  • Predictors and clinical implications of stent thrombosis in patients with ST-segment elevation myocardial infarction: Insights from the EXAMINATION trial.

    abstract:BACKGROUND:Few data are available about safety of second generation drug eluting stents in an all-comer ST elevation myocardial infarction (STEMI) population. We sought to investigate the predictors and clinical implications of 1-year stent thrombosis (ST) in patients with STEMI, included in the EXAMINATION trial. MET...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ijcard.2013.03.036

    authors: Brugaletta S,Sabate M,Martin-Yuste V,Masotti M,Shiratori Y,Alvarez-Contreras L,Cequier A,Iñiguez A,Serra A,Hernandez-Antolin R,Mainar V,Valgimigli M,Tespili M,den Heijer P,Bethencourt A,Vazquez N,Gomez-Lara J,Backx B,

    更新日期:2013-10-03 00:00:00

  • A monounsaturated fatty acid (oleic acid) modulates electrical activity in atrial myocytes with calcium and sodium dysregulation.

    abstract:BACKGROUND:Obesity and metabolic syndrome are important risk factors for atrial fibrillation. High plasma concentrations of monounsaturated fatty acids, including oleic acid (OLA), are frequently noted in obese individuals and patients with metabolic syndrome. However, it is not clear whether monounsaturated fatty acid...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2014.07.004

    authors: Lin YK,Chen YC,Kao YH,Tsai CF,Yeh YH,Huang JL,Cheng CC,Chen SA,Chen YJ

    更新日期:2014-09-01 00:00:00

  • Metformin and contrast-induced acute kidney injury in diabetic patients treated with primary percutaneous coronary intervention for ST segment elevation myocardial infarction: Amulticenter study.

    abstract:AIM:To analyze the association between chronic metformin treatment and the development of contrast-induced acute kidney injury (CI-AKI) after primary percutaneous coronary intervention (PCI) for ST segment elevation myocardial infarction (STEMI). METHODS:Patients with type 2 diabetes mellitus (T2DM) treated with PCI <...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ijcard.2016.06.076

    authors: Zeller M,Labalette-Bart M,Juliard JM,Potier L,Feldman LJ,Steg PG,Cottin Y,Roussel R

    更新日期:2016-10-01 00:00:00

  • Systemic embolism in takotsubo syndrome.

    abstract::A 57-year-old woman with acute left leg ischemia due to popliteal artery occlusion and deep T-wave inversion at ECG revealed she had suffered, the day before, from typical chest pain after a confrontational argument; yet, she had not sought medical assistance. Echocardiography showed left ventricular wall motion abnor...

    journal_title:International journal of cardiology

    pub_type: 信件

    doi:10.1016/j.ijcard.2007.12.074

    authors: Andò G,Saporito F,Trio O,Cerrito M,Oreto G,Arrigo F

    更新日期:2009-05-01 00:00:00

  • Time dependent changes in high density lipoprotein cholesterol and cardiovascular risk.

    abstract:BACKGROUND:High-density lipoprotein cholesterol (HDL-C) is a strong inverse predictor of cardiovascular events. The aim of the current study was to evaluate the correlation between changes in HDL-C and subsequent cardiovascular events. METHODS:Study population comprised 13,037 subjects free of cardiovascular disease w...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2014.03.022

    authors: Milwidsky A,Kivity S,Kopel E,Klempfner R,Berkovitch A,Segev S,Sidi Y,Goldenberg I,Maor E

    更新日期:2014-05-01 00:00:00

  • Negative pressure pulmonary edema complicating an electrophysiological study.

    abstract::We report on a case of acute non-cardiogenic negative-pressure pulmonary edema developed during an ablation procedure of an accessory pathway in a patient with no structural heart disease. That potentially serious complication has not been previously reported during an interventional cardiology procedure. ...

    journal_title:International journal of cardiology

    pub_type: 信件

    doi:10.1016/j.ijcard.2009.04.038

    authors: Pachón M,Arias MA,Castellanos E,Puchol A,Rodríguez-Padial L

    更新日期:2009-11-12 00:00:00

  • Long-term prognostic significance of urinary sodium concentration in patients with acute heart failure.

    abstract:BACKGROUND:Lower urinary sodium concentration (UNa) may reflect impaired renal perfusion, higher neurohormonal activity and diuretic resistance. However, the prognostic impact of UNa in patients with acute heart failure (AHF) has not been fully elucidated. METHODS:We investigate the association between UNa and clinica...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2017.08.053

    authors: Honda S,Nagai T,Nishimura K,Nakai M,Honda Y,Nakano H,Iwakami N,Sugano Y,Asaumi Y,Aiba T,Noguchi T,Kusano K,Yokoyama H,Ogawa H,Yasuda S,Anzai T,NaDEF investigators.

    更新日期:2018-03-01 00:00:00

  • Noninvasive assessment of left ventricular performance following transluminal coronary angioplasty.

    abstract::We studied 36 patients with successful transluminal coronary angioplasty (group 1) noninvasively using exercise electrocardiography, exercise T1-201 myocardial scintigraphy and equilibrium radionuclide ventriculography before and 3-5 days after the procedure. Six patients who underwent aortocoronary-bypass surgery (gr...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(83)90169-9

    authors: Kanemoto N,Hör G,Kober G,Maul FD,Klepzig H Jr,Standke R,Kaltenbach M

    更新日期:1983-06-01 00:00:00

  • Regulation of QT indices mediated by autonomic nervous function in patients with type 2 diabetes.

    abstract::Both the QT interval and QT dispersion in diabetic patients have been reported to increase with the progression of cardiac autonomic neuropathy and to have a prognostic value. We assessed the cardiac autonomic influences on QT indices using the measurements of baroreflex sensitivity, heart rate variability, and cardia...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2003.07.026

    authors: Takahashi N,Nakagawa M,Saikawa T,Watanabe M,Ooie T,Yufu K,Shigematsu S,Hara M,Sakino H,Katsuragi I,Tanaka K,Yoshimatsu H

    更新日期:2004-09-01 00:00:00

  • Association study of the thrombomodulin -33G>A polymorphism with coronary artery disease and myocardial infarction in Chinese Han population.

    abstract:BACKGROUND:Thrombomodulin (TM) is the anticoagulant endothelial cell membrane-bound protein cofactor in the thrombin-mediated activation of protein C. Recently, conflicting data have been reported regarding the possible contribution of the TM -33G>A polymorphism to coronary artery disease (CAD) or myocardial infarction...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2004.05.007

    authors: Zhao J,Zhou X,Huang J,Chen J,Gu D

    更新日期:2005-04-28 00:00:00

  • The change in concept and surgical treatment on Buerger's disease--personal experience and review.

    abstract::Buerger's disease was originally described by Leo Buerger in 1908 as thromboangitis obliterance and has been considered as one of the most intractable vasculitis syndromes in our country. This lesion is popularly seen in male young generation with a background history of heavy smoking. Buerger's disease in Japan has b...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0167-5273(98)00179-x

    authors: Nakajima N

    更新日期:1998-10-01 00:00:00

  • Amine-enriched surface modification facilitates expansion, attachment, and maintenance of human cardiac-derived c-kit positive progenitor cells.

    abstract:BACKGROUND:Stem cells have a low expansion rate and are difficult to maintain in vitro. To overcome the problems of cardiovascular regeneration, we developed a novel method of stem cell cultivation in culture vessels with amine and carboxyl coatings. METHODS AND RESULTS:We isolated cardiac stem/progenitor cells from i...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2012.09.065

    authors: Choi SH,Jung SY,Yoo SM,Asahara T,Suh W,Kwon SM,Baek SH

    更新日期:2013-09-20 00:00:00

  • A systematic review and meta-regression of temporal trends in the excess mortality associated with diabetes mellitus after myocardial infarction.

    abstract:BACKGROUND/OBJECTIVES:It is not well known whether the gap in outcomes after myocardial infarction (MI) between patients with and without diabetes mellitus (DM) has changed over time. We performed a systematic review and metaregression of temporal trends in the excess mortality associated with DM after MI. METHODS:We ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ijcard.2016.04.182

    authors: Bauters C,Lemesle G,de Groote P,Lamblin N

    更新日期:2016-08-15 00:00:00

  • Impacts of valve intervention on the Functional REServe of the Heart: The FRESH-valve pilot study.

    abstract:PURPOSE:Severe valve lesions require corrective interventions to avoid progression to heart failure (HF) and premature demise. We tested the hypothesis that despite operative risks, corrective valvular interventions will lead to significant improvements in overall cardiac pump function, especially before the onset of c...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2015.03.177

    authors: Tan DK,Hothi SS,Macdonald W,Schlosshan D,Tan LB

    更新日期:2015-01-01 00:00:00

  • Incidence and impact of renal dysfunction on clinical outcomes after transcatheter aortic valve implantation.

    abstract:BACKGROUND:The impact of baseline renal dysfunction on early and late clinical outcomes after transcatheter aortic valve implantation (TAVI) remains to be defined. METHODS:927 patients included in the prospective Bern TAVI registry were classified on the basis of the baseline estimated glomerular filtration rate (eGFR...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2017.09.201

    authors: Franzone A,Stortecky S,Pilgrim T,Asami M,Lanz J,Heg D,Langhammer B,Piccolo R,Lee JKT,Praz F,Räber L,Valgimigli M,Roost E,Windecker S

    更新日期:2018-01-01 00:00:00

  • Deterioration of indices of aortic augmentation and vascular age predate major cardiac events and interact with opiate dependence.

    abstract::Pulse wave analysis (PWA) by radial arterial tonometry is receiving increasing attention for the assessment of central vascular compliance in younger patients. We present five PWA studies performed prospectively on a patient with severe coronary artery disease, and find that the measures of central augmented pressure ...

    journal_title:International journal of cardiology

    pub_type: 信件

    doi:10.1016/j.ijcard.2009.03.015

    authors: Reece AS

    更新日期:2011-05-19 00:00:00

  • The endocannabinoid 2-arachidonoylglycerol inhibits endothelial function and repair.

    abstract:BACKGROUND:Endothelial dysfunction promotes atherogenesis, vascular inflammation, and thrombus formation. Reendothelialization after angioplasty is required in order to prevent stent failure. Previous studies have highlighted the role of 2-arachidonoylglycerol (2-AG) in murine experimental atherogenesis and in human co...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2020.08.042

    authors: Jehle J,Eich L,Danisch M,Bagheri S,Avraamidou E,Pfeifer P,Tiyerili V,Bindila L,Lutz B,Nickenig G

    更新日期:2021-01-15 00:00:00

  • ST-segment changes after direct current external cardioversion for atrial fibrillation. Incidence, characteristics and predictive factors.

    abstract:BACKGROUND:Incidence, characteristics and predictive factors of transient ST-segment changes after DC shock are poorly known. METHODS:91 consecutive pts referred for external cardioversion of atrial fibrillation (AF) (61 men, 69±10 yo) were prospectively included. The presence of ST elevation or depression was assesse...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2009.11.031

    authors: Rumeau P,Fourcade J,Duparc A,Hébrard A,Mondoly P,Rollin A,Massabuau P,Detis N,Elbaz M,Carrié D,Galinier M,Delay M,Maury P

    更新日期:2011-05-05 00:00:00

  • Clinical significance of papillary muscle late enhancement detected via cardiac magnetic resonance imaging in patients with single old myocardial infarction.

    abstract:BACKGROUND:Contrast-enhanced cardiac magnetic resonance imaging (MRI) can depict papillary muscle (PM) necrosis or fibrosis by late enhancement (LE) of PM, but its clinical significance in old myocardial infarction (OMI) has been little understood. METHODS:Myocardial LE and PM-LE were detected with contrast imaging in...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2010.04.037

    authors: Okayama S,Uemura S,Soeda T,Onoue K,Somekawa S,Ishigami K,Watanabe M,Nakajima T,Fujimoto S,Saito Y

    更新日期:2011-01-07 00:00:00

  • Cardiac tamponade as presentation of systemic amyloidosis.

    abstract::We present a patient with pericardial tamponade due to amyloid heart disease. A 64-yr-old man was admitted to the hospital because of fatigue and the abrupt development of chest pain and dyspnea. Echocardiography showed severe pericardial effusion and total pericardiectomy was necessary. Ten months later laboratory st...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(92)90115-j

    authors: Navarro JF,Rivera M,Ortuño J

    更新日期:1992-07-01 00:00:00

  • Atrial septal defect in adults > or =40 years old: negative impact of low arterial oxygen saturation.

    abstract:BACKGROUND:Although good prognosis and clinical long-term outcome have been commonly reported in minimally symptomatic adult patients with ASD, this information has been based on studies with a relatively small number of adult patients. We studied unoperated patients aged over 40 years to define the patterns of present...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/S0167-5273(03)00192-X

    authors: Rosas M,Attie F,Sandoval J,Castellano C,Buendía A,Zabal C,Granados N

    更新日期:2004-02-01 00:00:00

  • TGFβ1 contributes to cardiomyogenic-like differentiation of human bone marrow mesenchymal stem cells.

    abstract:BACKGROUND:The majority of the protocols for cardiomyocyte differentiation of MSC use 5-azacytidine as an inducer. As transforming growth factor β1 and 5-azacytidine share similar target signaling pathways, we examined whether transforming growth factor β1 can play a role in cardiac differentiation process in human mes...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2011.08.003

    authors: Mohanty S,Bose S,Jain KG,Bhargava B,Airan B

    更新日期:2013-02-10 00:00:00

  • Cardiac remodeling rather than disturbed myocardial energy metabolism is associated with cardiac dysfunction in diabetic rats.

    abstract:BACKGROUND:Diabetes mellitus (DM) alters the energy substrate metabolism in the heart and the early sign of diabetic cardiomyopathy is the diastolic dysfunction. Although it is known that the extracellular matrix must be altered in the presence of diabetes, its local regulation has not been fully elucidated. Our aim wa...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2006.01.027

    authors: Bollano E,Omerovic E,Svensson H,Waagstein F,Fu M

    更新日期:2007-01-08 00:00:00

  • The gender gap in risk factor control: Effects of age and education on the control of cardiovascular risk factors in male and female coronary patients. The EUROASPIRE IV study by the European Society of Cardiology.

    abstract:OBJECTIVE:The aim of this study was to investigate gender related differences in the management and risk factor control of patients with coronary heart disease (CHD), taking into account their age and educational level. METHODS:Analyses are based on the EUROASPIRE IV (EUROpean Action on Secondary and Primary Preventio...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2016.02.015

    authors: De Smedt D,De Bacquer D,De Sutter J,Dallongeville J,Gevaert S,De Backer G,Bruthans J,Kotseva K,Reiner Ž,Tokgözoğlu L,Clays E

    更新日期:2016-04-15 00:00:00

  • Low serum potassium levels and diabetes - An unfavorable combination in patients with heart failure and preserved ejection fraction.

    abstract:BACKGROUND:Heart failure with preserved ejection fraction (HFpEF) is among the most common forms of heart failure (HF). We aimed to investigate the prognostic significance of serum potassium levels and its interaction with type-2 diabetes mellitus in patients with HFpEF. METHODS:Consecutive HFpEF patients were prospec...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2020.04.029

    authors: Badr Eslam R,Öztürk B,Panzer S,Qin H,Duca F,Binder C,Rettl R,Dachs TM,Alasti F,Vila G,Bonderman D

    更新日期:2020-10-15 00:00:00

  • "The attack of the 52 cm lead": an unusual case of late cardiac perforation by a passive-fixation permanent pacemaker lead.

    abstract::We report a case of right ventricular perforation by a passive-tined permanent pacemaker lead detected 1 month after implantation. The pacemaker lead was seen to perforate through the myocardium and pericardium and moving freely in the mediastinum with no evidence of pericardial effusion. Extraction was uneventful. ...

    journal_title:International journal of cardiology

    pub_type: 信件

    doi:10.1016/j.ijcard.2006.05.064

    authors: Ramirez MF,Ching CK,Ho KL,Teo WS

    更新日期:2007-01-31 00:00:00

  • Attenuated renal excretory response to atrial natriuretic peptide in congestive heart failure in man.

    abstract::The renal and hormonal effects of atrial natriuretic peptide given as a bolus injection (2.0 micrograms/kg) were studied in 12 patients with congestive heart failure before and after treatment with captopril for 4 weeks and in 13 healthy control subjects. Atrial natriuretic peptide caused a rise in urinary excretion o...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/0167-5273(91)90153-g

    authors: Eiskjaer H,Bagger JP,Danielsen H,Jensen JD,Jespersen B,Thomsen K,Pedersen EB

    更新日期:1991-10-01 00:00:00

  • Anatomical consideration of the radial artery for transradial coronary procedures: arterial diameter, branching anomaly and vessel tortuosity.

    abstract:BACKGROUND:The radial artery is currently regarded as a useful vascular access site for coronary procedures. Adequate anatomical information of the radial artery should be helpful in performing the transradial coronary procedure. Therefore, we tried to evaluate the size of radial artery, the incidence and clinical sign...

    journal_title:International journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.ijcard.2004.03.061

    authors: Yoo BS,Yoon J,Ko JY,Kim JY,Lee SH,Hwang SO,Choe KH

    更新日期:2005-06-08 00:00:00

  • Is it time to change how we think about incomplete coronary revascularization?

    abstract::The optimal degree of revascularization for patients with chronic multivessel coronary artery disease remains an unsolved issue. Intuitively, complete revascularization decreases cardiovascular events and improves outcomes compared to incomplete procedures, but in recent years the concept of incomplete revascularizati...

    journal_title:International journal of cardiology

    pub_type: 社论

    doi:10.1016/j.ijcard.2016.09.055

    authors: Spadaccio C,Nappi F,Nenna A,Beattie G,Chello M,Sutherland FW

    更新日期:2016-12-01 00:00:00