Abstract:
:INTERNIST-I was an expert system designed in the early 1970's to diagnose multiple diseases in internal medicine by modelling the behaviour of clinicians. Its form and operation are described, and evaluations of the system are surveyed. The major result of the project was its knowledge base which has been used in successor systems for medical education and clinical use. We also survey the effects of the project through these systems, and conclude that the most successful of them in the near future is likely to be Quick Medical Reference (QMR) when used as an "electronic textbook" of medicine.
journal_name
Artif Intell Medjournal_title
Artificial intelligence in medicineauthors
Wolfram DAdoi
10.1016/0933-3657(94)00028-qsubject
Has Abstractpub_date
1995-04-01 00:00:00pages
93-116issue
2eissn
0933-3657issn
1873-2860pii
093336579400028Qjournal_volume
7pub_type
杂志文章abstract::The optical device LIPOMETER allows for non-invasive, quick, precise and safe determination of subcutaneous fat distribution, so-called subcutaneous adipose tissue topography (SAT-Top). In this paper, we show how the high-dimensional SAT-Top information of women with type-2 diabetes mellitus (non-insulin-dependent dia...
journal_title:Artificial intelligence in medicine
pub_type: 临床试验,杂志文章
doi:10.1016/s0933-3657(99)00017-2
更新日期:1999-10-01 00:00:00
abstract:AIM:A new automatic method for detecting specific points and lines (straight and curves) in dental panoramic radiographies (orthopantomographies) is proposed, where the human knowledge is mapped to the automatic system. The goal is to compute relevant mandibular indices (Mandibular Cortical Width, Panoramic Mandibular ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2020.101816
更新日期:2020-03-01 00:00:00
abstract::Deregulated splicing machinery components have shown to be associated with the development of several types of cancer and, therefore, the determination of such alterations can help the development of tumor-specific molecular targets for early prognosis and therapy. Determining such splicing components, however, is not...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2020.101950
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:The problem of designing and managing teams of workers that can collaborate working together towards common goals is a challenging one. Incomplete or ambiguous specification of responsibilities and accountabilities, lack of continuity in teams working in shifts, inefficient organization of teams due to lack o...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2011.08.005
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:Suitable techniques for microarray analysis have been widely researched, particularly for the study of marker genes expressed to a specific type of cancer. Most of the machine learning methods that have been applied to significant gene selection focus on the classification ability rather than the selection ab...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2011.06.008
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:This paper proposes a novel method for the extraction and classification of individual motor unit action potentials (MUAPs) from intramuscular electromyographic signals. METHODOLOGY:The proposed method automatically detects the number of template MUAP clusters and classifies them into normal, neuropathic or ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2005.09.002
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:In this paper a new nonlinear system identification approach is developed for dynamical quantification of cardiovascular regulation. This approach is specifically focused on the identification of the heart rate (HR) baroreflex mechanism. The principal objective of this paper is to improve the model accuracy i...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2011.01.002
更新日期:2011-05-01 00:00:00
abstract::The increasing access to brain signal data using electroencephalography creates new opportunities to study electrophysiological brain activity and perform ambulatory diagnoses of neurological disorders. This work proposes a pairwise distance learning approach for schizophrenia classification relying on the spectral pr...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2020.101852
更新日期:2020-05-01 00:00:00
abstract::Allowing exchange of information and cooperation among network-wide distributed and heterogeneous applications is a major need of current health-care information systems. The European project SynEx aims at developing an integration platform for both new and legacy applications on each partner's site. We developed, in ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(03)00007-1
更新日期:2003-03-01 00:00:00
abstract::Abnormalities in the organization of brain circuits may underlie many types of epilepsy. This hypothesis can best be evaluated in the case of temporal lobe epilepsy, where evidence of rewiring (synaptic reorganization) can be found in the dentate gyrus. Computer modeling of normal and reorganized dentate gyrus was use...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(98)00005-0
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVE:This paper presents a novel rule-based fuzzy classification methodology for survival/mortality prediction in severe burnt patients. Due to the ethical aspects involved in this medical scenario, physicians tend not to accept a computer-based evaluation unless they understand why and how such a recommendation i...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2013.12.006
更新日期:2014-03-01 00:00:00
abstract::The process of patient care performed by an anaesthesiologist during high invasive surgery requires fundamental knowledge of the physiologic processes and a long standing experience in patient management to cope with the inter-individual variability of the patients. Biomedical engineering research improves the patient...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(97)00020-1
更新日期:1997-09-01 00:00:00
abstract:OBJECTIVE:Recently, fuzzy soft sets-based decision making has attracted more and more interest. Although plenty of works have been done, they cannot provide the uncertainty or certainty of their results. To manage uncertainty is one of the most important and toughest tasks of decision making especially in medicine. In ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2016.04.004
更新日期:2016-05-01 00:00:00
abstract::Artificial intelligence (AI) will pave the way to a new era in medicine. However, currently available AI systems do not interact with a patient, e.g., for anamnesis, and thus are only used by the physicians for predictions in diagnosis or prognosis. However, these systems are widely used, e.g., in diabetes or cancer p...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2019.101706
更新日期:2019-09-01 00:00:00
abstract::The purpose of a clinical trial is to evaluate a new treatment procedure. When medical researchers conduct a trial, they recruit participants with appropriate health problems and medical histories. To select participants, they analyze medical records of the available patients, which has traditionally been a manual pro...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2004.01.017
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVES:In the presurgical analysis for drug-resistant focal epilepsies, the definition of the epileptogenic zone, which is the cortical area where ictal discharges originate, is usually carried out by using clinical, electrophysiological and neuroimaging data analysis. Clinical evaluation is based on the visual det...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2014.03.001
更新日期:2014-06-01 00:00:00
abstract::This paper presents a computer-based model for differential diagnosis of specific language impairment (SLI), a language disorder that, in many cases, cannot be easily diagnosed. This difficulty necessitates the development of a methodology to assist the speech therapist in the diagnostic process. The methodology tool ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(02)00076-3
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVES:Access to the world wide web and multimedia content is an important aspect of life. We present a web browser and a multimedia user interface adapted for control with a brain-computer interface (BCI) which can be used by severely motor impaired persons. METHODS:The web browser dynamically determines the most...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2014.12.001
更新日期:2015-01-01 00:00:00
abstract::Early recognition of heart disease plays a vital role in saving lives. Heart murmurs are one of the common heart problems. In this study, Artificial Neural Network (ANN) is trained with Modified Neighbor Annealing (MNA) to classify heart cycles into normal and murmur classes. Heart cycles are separated from heart soun...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2017.05.005
更新日期:2017-05-01 00:00:00
abstract::In this paper we describe how we generated written explanations to 'indirect users' of a knowledge-based system in the domain of drug prescription. We call 'indirect users' the intended recipients of explanations, to distinguish them from the prescriber (the 'direct' user) who interacts with the system. The Explanatio...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/0933-3657(95)00029-1
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVE:The successful preparation of cells for therapy depends on the characterization of causal factors affecting cell quality. Ultra scale-down methods are used to characterize cells in terms of their response to process engineering causal factors of hydrodynamic shear stress and time. This response is in turn cha...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2014.07.003
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND AND MOTIVATION:DNA microarray technology has made it possible to determine the expression levels of thousands of genes in parallel under multiple experimental conditions. Genome-wide analyses using DNA microarrays make a great contribution to the exploration of the dynamic state of genetic networks, and furt...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2005.02.007
更新日期:2005-09-01 00:00:00
abstract::HepatoConsult is a publicly available knowledge-based second opinion and documentation system aiding in the diagnosis of liver diseases. The positive results of a prospective diagnostic evaluation study encouraged its use in clinical routine, although the available hardware infrastructure was not optimal. The comments...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(01)00104-x
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVES:A well-developed appointment system can help increase the utilization of medical facilities in an outpatient department. This paper outlines the development of an appointment system that can make an outpatient department work more efficiently and improve patient satisfaction level. METHODS:A Markov decision...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2014.12.002
更新日期:2015-01-01 00:00:00
abstract::Hypertensive Retinopathy (HR) caused by hypertension is a retinal disease which may leads to vision loss and blindness. Computer aided diagnostic systems for various diseases are being used in clinics but there is a need to develop an automated system that detects and grades HR disease. In this paper, an automated sys...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2018.06.004
更新日期:2018-08-01 00:00:00
abstract::During the appointment booking process in out-patient departments, the level of patient satisfaction can be affected by whether or not their preferences can be met, including the choice of physicians and preferred time slot. In addition, because the appointments are sequential, considering future possible requests is ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2018.02.001
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:In this paper, we extend a preliminary proposal and discuss in a deeper and more formal way an approach to evaluate temporal similarity between clinical workflow cases (i.e., executions of clinical processes). More precisely, we focus on (i) the representation of clinical processes by using a temporal concept...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2008.07.013
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:The objective of the present work was to develop and compare methods for automatic detection of bilateral sleep spindles. METHODS AND MATERIALS:All-night sleep electroencephalographic (EEG) recordings of 12 healthy subjects with a median age of 40 years were studied. The data contained 6043 visually scored b...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2007.04.003
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:This paper identifies and reviews ethical issues associated with artificial intelligent care providers (AICPs) in mental health care and other helping professions. Specific recommendations are made for the development of ethical codes, guidelines, and the design of AICPs. METHODS:Current developments in the ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2014.06.004
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:There is an ongoing research effort devoted to characterize the signal regularity metrics approximate entropy (ApEn) and sample entropy (SampEn) in order to better interpret their results in the context of biomedical signal analysis. Along with this line, this paper addresses the influence of abnormal spikes ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2011.06.007
更新日期:2011-10-01 00:00:00