Somatosensory and brainstem auditory evoked potentials in cardiac arrest patients treated with hypothermia.

Abstract:

OBJECTIVE:To evaluate the prognostic value of short-latency median nerve somatosensory evoked potentials and brainstem auditory evoked potentials in outcome prediction for comatose cardiac arrest patients treated with hypothermia. DESIGN:Prospective, randomized, controlled trial of mild hypothermia after out-of-hospital cardiac arrest; a substudy of the European Hypothermia After Cardiac Arrest study. SETTING:Intensive care unit of a tertiary referral hospital (Helsinki University Central Hospital). PATIENTS:Sixty consecutive patients (aged 18-75 yrs) resuscitated from out-of-hospital ventricular fibrillation and comatose at 24 hrs after cardiac arrest; all patients were randomly assigned either to therapeutic hypothermia of 33 degrees C or normothermia. INTERVENTIONS:All patients received standard intensive care for at least 2 days. Patients randomized to hypothermia were cooled with an external cooling device for 24 hrs and then allowed to rewarm slowly for 12 hrs. In the normothermia group, the core temperature was kept below 38 degrees C with antipyretics and by physical means. The clinical outcome was assessed 6 months after cardiac arrest. MEASUREMENTS AND MAIN RESULTS:Somatosensory evoked potentials and brainstem auditory evoked potentials were recorded 24-28 hrs after cardiac arrest. All wave latencies were significantly prolonged in the hypothermia group. Bilaterally absent N20 waves predicted permanent coma with a specificity of 100% in both treatment groups. Brainstem auditory evoked potential recordings did not correlate with the outcome in either treatment group. CONCLUSIONS:The prognostic ability of median nerve short-latency somatosensory evoked potentials does not seem to be affected by therapeutic hypothermia. Brainstem auditory evoked potentials had no additional value in outcome prediction.

journal_name

Crit Care Med

journal_title

Critical care medicine

authors

Tiainen M,Kovala TT,Takkunen OS,Roine RO

doi

10.1097/01.ccm.0000171536.63641.d9

subject

Has Abstract

pub_date

2005-08-01 00:00:00

pages

1736-40

issue

8

eissn

0090-3493

issn

1530-0293

pii

00003246-200508000-00010

journal_volume

33

pub_type

临床试验,杂志文章,随机对照试验
  • Skeletal morbidity among survivors of critical illness.

    abstract:OBJECTIVES:To describe the incident fracture rate in survivors of critical illness and to compare fracture risk with population-matched control subjects. DESIGN:Retrospective longitudinal case-cohort study. SETTING:A tertiary adult intensive care unit in Australia. PATIENTS:All patients ventilated admitted to intens...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/CCM.0b013e318211ff3d

    authors: Orford NR,Saunders K,Merriman E,Henry M,Pasco J,Stow P,Kotowicz M

    更新日期:2011-06-01 00:00:00

  • National estimates of severe sepsis in United States emergency departments.

    abstract:OBJECTIVE:The emergency department (ED) often serves as the first site for the recognition and treatment of patients with suspected severe sepsis. However, few evaluations of the national epidemiology and distribution of severe sepsis in the ED exist. We sought to determine national estimates of the number, timing, ED ...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/01.CCM.0000277043.85378.C1

    authors: Wang HE,Shapiro NI,Angus DC,Yealy DM

    更新日期:2007-08-01 00:00:00

  • Uptake of glucose during continuous arteriovenous hemofiltration.

    abstract:OBJECTIVE:To quantify glucose balance related to continuous arteriovenous hemofiltration (CAVH) when a glucose-rich replacement fluid is used for the plasma ultrafiltrate removed. DESIGN:Prospective, nonintervention study. SETTING:Medical/surgical and cardiac surgical intensive care units of a university hospital. P...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-199308000-00014

    authors: Monaghan R,Watters JM,Clancey SM,Moulton SB,Rabin EZ

    更新日期:1993-08-01 00:00:00

  • Heat stress increases survival rates in lipopolysaccharide-stimulated rats.

    abstract:OBJECTIVE:To examine the hypothesis that heat stress applied after the administration of bacterial endotoxin is protective. DESIGN:Prospective, randomized, laboratory study. SETTING:University research laboratory. SUBJECTS:One hundred eleven adult male Sprague-Dawley rats (weight range 250 to 400 g). INTERVENTIONS:...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-199710000-00025

    authors: Chu EK,Ribeiro SP,Slutsky AS

    更新日期:1997-10-01 00:00:00

  • Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome.

    abstract:OBJECTIVE:The association between cigarette smoke exposure and the acute respiratory distress syndrome in patients with the most common acute respiratory distress syndrome risk factors of sepsis, pneumonia, and aspiration has not been well studied. The goal of this study was to test the association between biomarker-co...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/CCM.0000000000001089

    authors: Calfee CS,Matthay MA,Kangelaris KN,Siew ED,Janz DR,Bernard GR,May AK,Jacob P,Havel C,Benowitz NL,Ware LB

    更新日期:2015-09-01 00:00:00

  • Racemic versus l-epinephrine aerosol in the treatment of postextubation laryngeal edema: results from a prospective, randomized, double-blind study.

    abstract:OBJECTIVE:To determine whether any advantage exists using racemic epinephrine instead of the more potent and less expensive levo(1)-epinephrine in the treatment of postextubation laryngeal edema. DESIGN:Prospective, double-blind, randomized study. SETTING:Pediatric intensive care unit in a university teaching hospita...

    journal_title:Critical care medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Nutman J,Brooks LJ,Deakins KM,Baldesare KK,Witte MK,Reed MD

    更新日期:1994-10-01 00:00:00

  • External Corroboration That Corticosteroids May Be Harmful to Septic Shock Endotype A Patients.

    abstract:OBJECTIVES:We previously reported gene expression-based endotypes of pediatric septic shock, endotypes A and B, and that corticosteroid exposure was independently associated with increased mortality among pediatric endotype A patients. The Vasopressin vs Norepinephrine as Initial Therapy in Septic Shock trial tested th...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/CCM.0000000000004709

    authors: Wong HR,Hart KW,Lindsell CJ,Sweeney TE

    更新日期:2021-01-01 00:00:00

  • Intracranial pressure monitoring and case mix-adjusted mortality in intracranial hemorrhage.

    abstract:OBJECTIVE:Intracranial pressure (ICP) monitoring is frequently used in intensive care treatment of patients with intracranial hemorrhage. Data demonstrating an improved outcome from this intervention are lacking. We analyzed standardized mortality ratios in patients with and without ICP monitoring to determine its effi...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/01.CCM.0000065270.53951.9E

    authors: Valentin A,Lang T,Karnik R,Ammerer HP,Ploder J,Slany J

    更新日期:2003-05-01 00:00:00

  • Angiotensin-(1-7) protects from experimental acute lung injury.

    abstract:OBJECTIVES:Recently, recombinant angiotensin-converting enzyme 2 was shown to protect mice from acute lung injury, an effect attributed to reduced bioavailability of angiotensin II. Since angiotensin-converting enzyme 2 metabolizes angiotensin II to angiotensin-(1-7), we hypothesized that this effect is alternatively m...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/CCM.0b013e31828a6688

    authors: Klein N,Gembardt F,Supé S,Kaestle SM,Nickles H,Erfinanda L,Lei X,Yin J,Wang L,Mertens M,Szaszi K,Walther T,Kuebler WM

    更新日期:2013-11-01 00:00:00

  • Thrombocytopenia in patients in the medical intensive care unit: bleeding prevalence, transfusion requirements, and outcome.

    abstract:OBJECTIVE:To determine prevalence, risk factors, and outcome of thrombocytopenia in medical intensive care patients. DESIGN:Prospective observational study. SETTING:The 12-bed medical intensive care unit of a university hospital. PATIENTS:All consecutively admitted patients with normal platelet count at admission an...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-200208000-00015

    authors: Strauss R,Wehler M,Mehler K,Kreutzer D,Koebnick C,Hahn EG

    更新日期:2002-08-01 00:00:00

  • Trauma index revisited: a better triage tool.

    abstract::In the development of triage and bypass protocols, many different scoring systems and triage criteria are being used. Our purpose was to evaluate the Revised Trauma Index (RTI) as a triage tool for both its severity prediction ability and triage accuracy. A total of 2,340 trauma admissions were evaluated using the RTI...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-199002000-00010

    authors: Smith JS Jr,Bartholomew MJ

    更新日期:1990-02-01 00:00:00

  • Cardiopulmonary outcome of neonatal extracorporeal membrane oxygenation at ages 10-15 years.

    abstract:OBJECTIVE:The purpose of this study was to evaluate the long-term cardiopulmonary outcome at ages 10-15 yrs following neonatal extracorporeal membrane oxygenation (ECMO). The specific aims of the study were to assess baseline aerobic capacity, cardiac function, and pulmonary function in neonatal ECMO survivors using gr...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/01.CCM.0000084856.00372.CE

    authors: Boykin AR,Quivers ES,Wagenhoffer KL,Sable CA,Chaney HR,Glass P,Bahrami KR,Short BL

    更新日期:2003-09-01 00:00:00

  • Intermittent mandatory ventilation in the neonate.

    abstract::Intermittent Mandatory Ventilation (IMV) provides an alternative method of support to assisted and controlled mechanical ventilation in neonates with acute respiratory failure. Specific advantages include the use of only the level of mechanical support which is required on an individual basis. Because intrapleural pre...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-197701000-00004

    authors: Kirby RR

    更新日期:1977-01-01 00:00:00

  • Inflammation at the insertion site is not predictive of catheter-related bloodstream infection with short-term, noncuffed central venous catheters.

    abstract:BACKGROUND:Noncuffed, percutaneously inserted central venous catheters (CVCs) are widely used and cause at least 250,000 bloodstream infections (BSIs) in U.S. hospitals each year. We report a prospective study to determine whether inflammation at the insertion site is predictive of CVC-related BSI. METHODS:Percutaneou...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-200212000-00003

    authors: Safdar N,Maki DG

    更新日期:2002-12-01 00:00:00

  • A method for predicting survival and mortality of ICU patients using objectively derived weights.

    abstract::Data at ICU admission and after 24 h in the ICU were collected on 755 patients, to derive multiple logistic regression models for predicting hospital mortality. The derived models contained relatively few and easily obtained variables. The weight associated with each variable was determined objectively. There were sev...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-198507000-00001

    authors: Lemeshow S,Teres D,Pastides H,Avrunin JS,Steingrub JS

    更新日期:1985-07-01 00:00:00

  • Intravenous ibuprofen blocks the hypoxemia of pulmonary glass bead embolism in the dog.

    abstract::To determine the influence of arachidonic acid metabolites on acute lung injury induced by glass bead embolism, two groups of animals were studied before and after the pulmonary artery pressure was doubled by glass bead embolism. One group represented an untreated time control (n = 6) while the second group (n = 6) wa...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-198809000-00007

    authors: Calvin JE,Dervin G

    更新日期:1988-09-01 00:00:00

  • Meconium and amniotic fluid embolism: effects on coagulation in pregnant mini-pigs.

    abstract:OBJECTIVE:A hallmark of amniotic fluid embolism is the induction of coagulation defects. Little is known about the nature of these defects or the causative agent or agents. The purpose of this study was to assess the effects of meconium containing (native) meconium-amniotic-fluid infusion (MAFI) and meconium-free (cent...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-199902000-00042

    authors: Petroianu GA,Altmannsberger SH,Maleck WH,Assmus HP,Friedberg C,Bergler WF,Rüfer R

    更新日期:1999-02-01 00:00:00

  • Meta-Analysis of Therapeutic Hypothermia for Traumatic Brain Injury in Adult and Pediatric Patients.

    abstract:OBJECTIVE:Therapeutic hypothermia has been used to attenuate the effects of traumatic brain injuries. However, the required degree of hypothermia, length of its use, and its timing are uncertain. We undertook a comprehensive meta-analysis to quantify benefits of hypothermia therapy for traumatic brain injuries in adult...

    journal_title:Critical care medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/CCM.0000000000002205

    authors: Crompton EM,Lubomirova I,Cotlarciuc I,Han TS,Sharma SD,Sharma P

    更新日期:2017-04-01 00:00:00

  • Hemoptysis and pneumothorax after removal of a persistently wedged pulmonary artery catheter.

    abstract::Significant resistance was encountered when an attempt was made to withdraw a persistently wedged pulmonary artery catheter. A small amount of air was injected into the balloon lumen with great difficulty. This injection freed the catheter which was removed, but produced significant sudden hemoptysis and a pneumothora...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-198106000-00013

    authors: Farber DL,Rose DM,Bassell GM,Eugene J

    更新日期:1981-06-01 00:00:00

  • Do-not-resuscitate orders in a children's hospital.

    abstract:OBJECTIVES:a) To quantify the use of do-not-resuscitate orders in a tertiary care children's hospital; and b) to characterize the circumstances in which such orders are written. DESIGN:Retrospective chart review. SETTING:University teaching hospital. PATIENTS:All inpatients who died in an urban children's hospital o...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-199301000-00012

    authors: Lantos JD,Berger AC,Zucker AR

    更新日期:1993-01-01 00:00:00

  • Prolonged mechanical ventilation alters diaphragmatic structure and function.

    abstract:OBJECTIVE:To review current knowledge about the impact of prolonged mechanical ventilation on diaphragmatic function and biology. MEASUREMENTS:Systematic literature review. CONCLUSIONS:Prolonged mechanical ventilation can promote diaphragmatic atrophy and contractile dysfunction. As few as 18 hrs of mechanical ventil...

    journal_title:Critical care medicine

    pub_type: 杂志文章,评审

    doi:10.1097/CCM.0b013e3181b6e760

    authors: Powers SK,Kavazis AN,Levine S

    更新日期:2009-10-01 00:00:00

  • Hospitals with the highest intensive care utilization provide lower quality pneumonia care to the elderly.

    abstract:OBJECTIVE:Quality of care for patients admitted with pneumonia varies across hospitals, but causes of this variation are poorly understood. Whether hospitals with high ICU utilization for patients with pneumonia provide better quality care is unknown. We sought to investigate the relationship between a hospital's ICU a...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/CCM.0000000000000925

    authors: Sjoding MW,Prescott HC,Wunsch H,Iwashyna TJ,Cooke CR

    更新日期:2015-06-01 00:00:00

  • Hypertonic saline versus mannitol for the treatment of elevated intracranial pressure: a meta-analysis of randomized clinical trials.

    abstract:OBJECTIVES:Randomized trials have suggested that hypertonic saline solutions may be superior to mannitol for the treatment of elevated intracranial pressure, but their impact on clinical practice has been limited, partly by their small size. We therefore combined their findings in a meta-analysis. DATA SOURCES:We sear...

    journal_title:Critical care medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/CCM.0b013e318206b9be

    authors: Kamel H,Navi BB,Nakagawa K,Hemphill JC 3rd,Ko NU

    更新日期:2011-03-01 00:00:00

  • Indirect calorimetry in mechanically ventilated infants and children: measurement accuracy with absence of audible airleak.

    abstract:OBJECTIVE:To establish the effect of an audible airleak (around an endotracheal tube) on oxygen consumption (VO2) measurements in pediatric ICU patients. DESIGN:Prospective trial comparing VO2 measurements before and after deflation of the endotracheal tube cuff. SETTING:Pediatric ICU in a large pediatric tertiary ca...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-199206000-00012

    authors: Chwals WJ,Lally KP,Woolley MM

    更新日期:1992-06-01 00:00:00

  • Driving pressure and arterial carbon dioxide tension during high-frequency jet ventilation in postoperative patients.

    abstract::To achieve normocarbia during conventional mechanical ventilation, ventilator settings are determined initially on the basis of body weight. The best ventilator settings for CO2 elimination during high-frequency jet ventilation (HFJV) have not been so clearly defined. A recent study has suggested that eucarbia will be...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-198801000-00012

    authors: Bayly R,Sladen A,Tyler IL,Echegaray RF,Klain M,Guntupalli K

    更新日期:1988-01-01 00:00:00

  • Topical inhibition of nuclear factor-kappaB enhances reduction in lung edema by surfactant in a piglet model of airway lavage.

    abstract:OBJECTIVE:Acute respiratory distress syndrome is occasionally seen in newborn infants due to a severe inflammatory process in the lungs that affects capillary-alveolar permeability, epithelial integrity, and type I and II pneumocyte function. The aim of this study was to investigate the effect of a topically applied nu...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/01.ccm.0000166371.18066.5e

    authors: Ankermann T,Reisner A,Wiemann T,Krams M,Köhler H,Krause MF

    更新日期:2005-06-01 00:00:00

  • Late diagnosis of ornithine transcarbamylase defect in three related female patients: polymorphic presentations.

    abstract:OBJECTIVE:To describe three female patients of one family with different phenotypes of the same mutation of the ornithine transcarbamylase gene. X-linked inherited ornithine transcarbamylase deficiency is the most frequent urea cycle disorder. Many of the hemizygous males die during the neonatal period. Women, who are ...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-200201000-00035

    authors: Legras A,Labarthe F,Maillot F,Garrigue MA,Kouatchet A,Ogier de Baulny H

    更新日期:2002-01-01 00:00:00

  • Evaluating the management of septic shock using patient simulation.

    abstract:OBJECTIVE:Develop a scoring system that can assess the management of septic shock by individuals and teams. DESIGN:Retrospective review of videotapes of critical care house staff managing a standardized simulation of septic shock. SETTING:Academic medical center; videotapes were made in a recreated intensive care uni...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/01.CCM.0000256849.75799.20

    authors: Ottestad E,Boulet JR,Lighthall GK

    更新日期:2007-03-01 00:00:00

  • Colloid solution therapy of experimental ischemic intestinal shock in rats.

    abstract::This study evaluated the effects of varying colloid concentrations and infusion volumes on survival and plasma volume expansion in rats subjected to an intestinal ischemic shock. Up to 10% solutions of albumin and dextran-40 in lactated Ringer's solution, infused over a 6-h period, had the same effects on hematocrit (...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-198509000-00003

    authors: Dawidson I,Ottosson J,Reisch J

    更新日期:1985-09-01 00:00:00

  • Hypophosphatemia induced by mechanical ventilation in patients with chronic obstructive pulmonary disease.

    abstract::The aim of this study was to assess prospectively the variations of serum phosphorus concentration (P) after onset of mechanical ventilation (MV) in patients with chronic obstructive pulmonary disease (COPD) and acute respiratory acidosis. In 14 COPD patients, we measured P, PaCO2, and pH, immediately before MV (H0), ...

    journal_title:Critical care medicine

    pub_type: 杂志文章

    doi:10.1097/00003246-198911000-00005

    authors: Laaban JP,Grateau G,Psychoyos I,Laromiguière M,Vuong TK,Rochemaure J

    更新日期:1989-11-01 00:00:00