Abstract:
OBJECTIVE:To screen copper and noncopper paints for their bactericidal effectiveness in rendering surfaces self-disinfecting. DESIGN:Tested paints were applied to glass coverslips, cured, inoculated with test organisms (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Enterococcus faecalis), and dried. After 0, 24, or 48 hours, surviving organisms were eluted and enumerated, and counts compared with those obtained from inoculated control (unpainted) coverslips for the corresponding time periods. Copper elution from select copper paints was quantified by complete immersion of coated coverslips followed by spectroscopic analysis to infer a threshold relationship between kill and copper release. RESULTS:Nearly all of the tested copper paints were capable of reducing organism counts to negligible levels within 24 hours. Exterior latex paints supplemented with a fungicide were similarly efficacious. Standard interior latex paint reduced bacterial counts to nearly zero within 24 hours for E coli and P aeruginosa, and to zero within 48 hours for E faecalis. However, substantial survival of S aureus occurred (up to 4 logs at 24 hours). Chi-squared analysis of elution and cidal data indicated that lethality was dependent on copper release in excess of 32 micrograms. CONCLUSION:The data support presumptive bactericidal claims for several copper and noncopper paints. Despite controversy over environment-based contagion, such paints could be used to render surfaces self-disinfecting in strategic locations where environmental causation of nosocomial infections is suspected.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
Cooney TEdoi
10.1086/648361subject
Has Abstractpub_date
1995-08-01 00:00:00pages
444-50issue
8eissn
0899-823Xissn
1559-6834journal_volume
16pub_type
杂志文章abstract:OBJECTIVE:To determine persistence of coagulase-negative staphylococci (CNS) on a hematology-oncology ward and to determine the value of phenotypic and genotypic procedures for establishing clonality among CNS isolates. DESIGN:Strains of CNS isolated from bacteremic patients (n = 139) were typed by biochemical reactiv...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract:BACKGROUND:Clostridium difficile is a major cause of infectious diarrhea in hospitalized patients. Between August 2003 and January 2004, we experienced an increase in the incidence of C. difficile-associated disease. We describe the investigation into and management of the outbreak in this article. METHODS:A total of ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/519181
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVE:To ascertain the etiology and outcome of episodes of bacteremia and fungemia over a three-year period (1990-1992) in patients with hematological malignancies. DESIGN:Retrospective study. SETTING:Hematology service of a 1,500-bed Spanish university hospital. RESULTS:Of a total of 178 episodes of significant...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,评审
doi:10.1086/646869
更新日期:1994-02-01 00:00:00
abstract:OBJECTIVE:To investigate an outbreak in neonates of Enterobacter cloacae infection resistant to third-generation cephalosporins. DESIGN:A retrospective study of an outbreak in the neonatal intensive care unit (NICU) and review of E cloacae isolates in pediatric wards and other intensive care units from June 1992 throu...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646998
更新日期:1995-01-01 00:00:00
abstract::We investigated 4 hepatitis C virus (HCV) infection outbreaks at hemodialysis units to identify practices associated with transmission. Apparent failures to follow recommended infection control precautions resulted in patient-to-patient HCV transmission, through cross-contamination of the environment or intravenous me...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/605472
更新日期:2009-09-01 00:00:00
abstract::The rate of purified protein derivative (PPD) conversion in workers at our hospital increased to 1.7% in 1991. After implementation of mandatory respiratory isolation of patients with community-acquired pneumonia, the rate dropped to 0.6%. This policy may protect workers in institutions where the majority of patients ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647675
更新日期:1997-08-01 00:00:00
abstract::Of 49 long-term care facility residents, 21 (43%) were colonized with 2 or more distinct strains of Escherichia coli. There were no significant risk factors for colonization with multiple strains of E. coli. These results suggest that future efforts to efficiently identify the diversity of colonizing strains will be c...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/597234
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:To determine whether the molecular epidemiological characteristics of methicillin-resistant Staphylococcus aureus (MRSA) had changed in a level III neonatal intensive care unit (NICU). DESIGN:Retrospective review of medical records. SETTING:Level III NICU of a university-affiliated children's hospital in Ne...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/652526
更新日期:2010-06-01 00:00:00
abstract::Water samples taken from extracorporeal membrane oxygenator (ECMO) devices used at University Hospitals Birmingham yielded high total viable counts (TVCs) containing a variety of microorganisms, including M. chimaera. Disinfection resulted in the reduction of TVCs and eradication of Mycobacterium chimaera. Weekly disi...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2017.163
更新日期:2017-10-01 00:00:00
abstract::We compared cleaning rates associated with use of a white ultraviolet (UV) powder versus a transparent UV gel among units with various degrees of previous experience with UV powder. The study outcome was the presence of discordant cleaning (removal of powder without the removal of gel, or vice versa). We found higher ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/663713
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Prepared ready-to-eat salads and ready-to-eat delicatessen-style meats present a high risk for Listeria contamination. Because no foodborne illness risk management guidelines exist specifically for US hospitals, a survey of New York City (NYC) hospitals was conducted to characterize policies a...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/658943
更新日期:2011-04-01 00:00:00
abstract::Whole-genome sequencing (WGS) has yielded new insights into the transmission patterns of healthcare facility-onset Clostridioides difficile infection (HO-CDI). WGS results prompted a focused diagnostic stewardship program, which was associated with a significant and sustained decrease in HO-CDI at large, urban hospita...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2019.124
更新日期:2019-07-01 00:00:00
abstract::The annual cost of a screening program to detect methicillin-resistant Staphylococcus aureus (MRSA) in a teaching hospital in Spain was 10,261 Euro. The average cost per MRSA infection was 2,730 Euro; therefore, the cost of the program would be covered if it only prevented 4 infections per year (11% of the total numbe...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/507968
更新日期:2006-11-01 00:00:00
abstract::The cumulative risk of human immunodeficiency virus (HIV) infection over a healthcare career has rarely been estimated, but is more relevant to the description of an occupational hazard than the risk of seroconversion from a single exposure. We describe a model for assessing the individualized risk for HIV infection a...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646161
更新日期:1990-05-01 00:00:00
abstract:OBJECTIVE:To investigate the relationship between contact precautions and delirium among inpatients, adjusting for other factors. DESIGN:Retrospective cohort study. SETTING:A 662-bed tertiary care center. PATIENTS:All nonpyschiatric adult patients admitted to a tertiary care center from 2007 through 2009. METHODS:G...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/663340
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To determine the impact of the introduction of a plastic shield-shaped device (Needleguard, Biosafe, Auckland, New Zealand) and education program designed to allow safer recapping, on recorded rates of needlestick injury. DESIGN:A before-after trial with a two-year duration of follow-up. SETTING:Tertiary re...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646328
更新日期:1991-04-01 00:00:00
abstract::This article is the first in a two-part series discussing and illustrating the application of statistical process control (SPC) to processes often examined by hospital epidemiologists. The basic philosophical and theoretical foundations of statistical quality control and their relation to epidemiology are emphasized i...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,评审
doi:10.1086/647795
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVE:To describe the incidence of device-associated nosocomial infections in medical-surgical intensive care units (MS ICUs) in a university hospital in Turkey and compare it with National Nosocomial Infections Surveillance (NNIS) system rates. DESIGN:Prospective surveillance study during a period of 27 months. D...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/503344
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:To determine differences in healthcare costs between cases of methicillin-susceptible Staphylococcus aureus (MSSA) infection and methicillin-resistant S. aureus (MRSA) infection in adults. DESIGN:Retrospective study of all cases of S. aureus infection. SETTING:Department of Veterans Affairs hospital and ass...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/651094
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:To determine the attributable (direct) mortality and morbidity caused by carbapenem-resistant Klebsiella pneumoniae bacteremia. DESIGN:A matched retrospective, historical cohort design, using a stepwise procedure to stringently match the best control subjects to the best case subjects. SETTING:A 1,000-bed t...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/605922
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Antiviral prophylaxis is recommended for the control of institutional influenza A outbreaks. In long-term-care institutions other than nursing homes, neither the seriousness of influenza nor the risks and benefits of antiviral prophylaxis is clearly understood. We studied the severity of illne...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502326
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:Evaluate the clinical impact of the implementation of VERIGENE gram-positive blood culture testing (BC-GP) coupled with antimicrobial stewardship result notification for children with positive blood cultures. DESIGN:Quasi-experimental study. SETTING:Quaternary children's hospital. PATIENTS:Hospitalized chi...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.191
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE: To report the results of a surveillance study on surgical site infections (SSIs) conducted by the International Nosocomial Infection Control Consortium (INICC). DESIGN: Cohort prospective multinational multicenter surveillance study. SETTING: Eighty-two hospitals of 66 cities in 30 countries (Argentina, Br...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1086/670626
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that antibiotic use could be controlled or improved in a community teaching hospital, with improvement defined as reductions in overall use, overall cost, and antimicrobial resistance. DESIGN:Interventional study with historical comparison. SETTING:A not-for-profit, 900-bed community ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/500419
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:Pathogens can survive for extended periods when incorporated into biofilm on dry hospital surfaces (ie, dry-surface biofilm, DSB). Bacteria within biofilm are protected from desiccation and have increased tolerance to cleaning agents and disinfectants. OBJECTIVE:We hypothesized that gloved hands of healthca...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2018.285
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To develop new evaluation indices of infection control and to use them to evaluate Korean infection surveillance and control programs (ISCPs). DESIGN:We performed a questionnaire-based survey to 164 acute care general hospitals throughout the Republic of Korea that had more than 300 beds. Study methods were ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/512632
更新日期:2007-04-01 00:00:00
abstract::Infection control in British nursing homes is different from that in U.S. nursing homes in seveal ways. Most British nursing homes, for example, do not have a designated on-site infection control nurse, and several agencies are responsible for regulatory oversight. This article discusses the state of infection control...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502198
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVE:The incidence of extended-spectrum beta-lactamase (ESbetaL)-mediated resistance has increased markedly during the past decade. Risk factors for colonization with ESbetaL-producing Escherichia coli and Klebsiella species (ESbetaL-EK) remain unclear, as do methods to control their further emergence. DESIGN:Cas...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502045
更新日期:2002-05-01 00:00:00
abstract:OBJECTIVE:To establish a new, rapid, and reliable genotypic fingerprinting technique for methicillin-resistant Staphylococcus aureus (MRSA) typing in routine epidemiological surveillance. DESIGN:The method is based on polymerase chain reaction (PCR) restriction fragment-length polymorphism (RFLP) following HaeII diges...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501903
更新日期:2001-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of a new monochloramine generation system for control of Legionella in a hospital hot water distribution system. SETTING:A 495-bed tertiary care hospital in Pittsburgh, Pennsylvania. The hospital has 12 floors covering approximately 78,000 m(2). METHODS:The hospital hot water system...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/678418
更新日期:2014-11-01 00:00:00