Abstract:
:Benzene (Bz) is an important industrial chemical, a petroleum by-product, a component of unleaded gas, and thus a ubiquitous environmental pollutant. It is well established that this organic solvent possesses neurotoxic and behavioral effects. However, the neurochemical mechanism of the solvent action remains obscure. The aminopeptidases (AP) are proteolytic enzymes that have been proposed as a candidate regulator of the degradation of several neuropeptides. In this work, changes in Lys- and Leu-aminopeptidase activities in several rat brain regions after benzene administration are described. The AP activity was determined by measuring the rate of hydrolysis of the artificial substrates Lys- and Leu-2-naphthylamides (fluorimetrically detected in triplicate). Both enzyme activities decrease in the thalamus, hypothalamus, hippocampus, and amygdala after Bz treatment. It is suggested that these aminopeptidase activities play a part in the benzene action mechanism, possibly by regulating the activity of several neuroactive peptides.
journal_name
Arch Environ Contam Toxicoljournal_title
Archives of environmental contamination and toxicologyauthors
de Gandarias JM,Casis O,Irazusta J,Echevarría E,Casis Ldoi
10.1007/BF00212097subject
Has Abstractpub_date
1992-04-01 00:00:00pages
345-8issue
3eissn
0090-4341issn
1432-0703journal_volume
22pub_type
杂志文章abstract::In vivo and in vitro experiments elicited different responses to ammonia nitrogen (ammonia-N) of gill and mantle Na,K-ATPase and ouabain-insensitive Na-ATPase activities in the Philippine clam Tapes philippinarum. Short-term (120 h) exposed clams to sublethal ammonia-N (NH(3)+NH (4) (+) ) concentrations (1.5 and 3.0 m...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-007-9102-5
更新日期:2008-07-01 00:00:00
abstract::The concentrations of polychlorinated dibenzo-p-dioxins (PCDD) and polychlorinated dibenzofurans (PCDF) were determined in soil samples taken from 24 sites in the vicinity of a municipal solid waste incinerator (Montcada, Barcelona, Spain). Samples were collected within a radius of 3 km in each of the three main direc...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s002449900249
更新日期:1997-10-01 00:00:00
abstract::A test battery, composed of a range of biological assays, was applied to evaluate the ecological health of soil aged for 69 days and spiked with a range of pyrene levels (1.04, 8.99, 41.5, 72.6, 136, and 399 μg g(-1) dry soil; Soxhlet-extracted concentrations after 69 days of aging). Chinese cabbage (Brassica rapa), e...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-012-9793-0
更新日期:2012-11-01 00:00:00
abstract::The concentrations of butyltins (BTs) in sediment from Peninsular Malaysia along the Strait of Malacca and their spatial distribution are discussed. The concentrations of BTs were high in the southern part of Peninsular Malaysia where there is a lot of ship traffic, because trade is prosperous. The concentrations of m...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-008-9252-0
更新日期:2009-04-01 00:00:00
abstract::In the wake of the Deepwater Horizon incident (2010) in the Gulf of Mexico, an abundance of research studies have been performed, but the methodologies used have varied making comparisons and replication difficult. In this study, acute toxicity tests with mysids and inland silversides were performed to examine the eff...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-015-0228-6
更新日期:2016-02-01 00:00:00
abstract::Trace elements were analyzed in organisms collected at five sampling stations along coastal areas of Linosa Island, Sicily (southern Tyrrhenian Sea, Italy). Concentrations of Cd, Cr, Cu, Pb, and Zn were measured in Posidonia oceanica L. Delile tissues, the two brown algae Padina pavonica (L.) Thivy and Cystoseira sp.,...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-009-9331-x
更新日期:2010-01-01 00:00:00
abstract::Exposure to fluoride concentrations above a threshold of 1.5 mg/L can cause joint pains, restricted mobility, skeletal and dental fluorosis. This study aims to determine the hydrochemical evolution of the fluoride-rich groundwater and estimate the risk of fluoride exposure to the residents of semi-arid northeastern pa...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-020-00794-z
更新日期:2021-01-01 00:00:00
abstract::From 1997 until 1999 the extent and the ecological effects of zinc, copper, lead, and cadmium pollution were studied in different reaches of the South American Pilcomayo River. A comparison of metal concentrations in water, sediment, and chironomid larvae, as well as the diversity of macroinvertebrate species, was mad...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-002-2042-1
更新日期:2003-04-01 00:00:00
abstract::Urinary hippuric acid, phenol, and o-cresol, which are biomarkers for toluene, benzene, and phenol exposures, are usually present in a significant amount in urine collected from subjects who have not been occupationally exposed to the organic solvents. With the improvement of working environments, the urinary concentr...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s002449900015
更新日期:1996-01-01 00:00:00
abstract::The in vivo toxic effects of sublethal treatment of 40 and 80% of 48-h LD(50) of topically applied trace metals [copper (Cu), lead (Pb), and zinc (Zn)] on oxidative stress biomarkers in the digestive gland of Theba pisana were examined. Oxidative individual perturbations were assessed by measuring nonenzymatic (glutat...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-009-9380-1
更新日期:2010-04-01 00:00:00
abstract::We analyzed the accumulation of inorganic and organic toxicants in tadpoles from nine populations of the common frog (Rana temporaria) at different altitudes of the Hohe Tauern National Park in Austria). Lead and cadmium concentrations in tadpoles increased with the acidity and metal-to-HCO3(-) ratio in the water exce...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-004-0188-8
更新日期:2005-08-01 00:00:00
abstract::Scientists interested in contamination normally deal only with pollution itself, not with people's perceptions of pollution or the relationship between pollution and land use. The overall objective of this article was to examine the relationship between people's perceptions of pollution and their views on future land ...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-008-9141-6
更新日期:2008-10-01 00:00:00
abstract::The Army is replacing traditional munitions with insensitive munitions (IM) resistant to accidental detonation. The aquatic toxicity of 1-methyl-3-nitroguanidine (MeNQ), which is being assessed for potential use in IM formulations, remains largely untested. The present study fills a number of critical data gaps for Me...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-020-00796-x
更新日期:2021-01-02 00:00:00
abstract::The golden-brown algae Isochrysis galbana, a primary producer, was used to determine the influence of the chemical dispersing agent, Corexit 9527((R)), on the bioavailability of naphthalene. Cells were exposed to laboratory preparations of either the water-accommodated fraction (WAF) of Prudhoe Bay crude oil (PBCO) or...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s002449900376
更新日期:1998-08-01 00:00:00
abstract::The Tinto and Odiel river basins (SW Spain) are known worldwide for their unique water characteristics. Such uniqueness is a consequence of their flow through the Iberian Pyrite Belt (an area rich in metal sulphides) and the mining activities in the basins. A process of sulphide oxidation occurs in this region, which ...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-017-0409-6
更新日期:2018-01-01 00:00:00
abstract::The effects of a 7-day exposure of 3-day-old wheat plantsto increasing Cd concentrations are described, with special attention beinggiven to chloroplast ultrastructural changes, chlorophyll fluorescenceresponses, chlorophyll and nutrient concentration changes as well as growthchanges of the whole plant. The plants tre...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s002449900168
更新日期:1997-02-01 00:00:00
abstract::We examined possible adverse effects of heavy metals on microbial activity, biomass, and community composition using the simultaneously extracted metals (SEM)/acid-volatile sulfide (AVS)-based approach and measurements of exchangeable metal concentrations in three paddy soils (wastewater-contaminated soil, mine-contam...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-017-0387-8
更新日期:2017-04-01 00:00:00
abstract::The effects of zinc (Zn) deficiency and repeated exposure to cadmium (Cd) on the accumulation and distribution of metallothionein (MT), Cd and Zn in the liver and kidney were studied. Male Sprague-Dawley rats were fed either a Zn-deficient (1 ppm) or a Zn-adequate (40 ppm) diet during the experiment, and the rats were...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/BF01055026
更新日期:1989-07-01 00:00:00
abstract::The present study estimated hexabromocyclododecane (HBCD) as a sum of three main isomers (α, β, and γ) and tetrabromobisphenol A (TBBPA) in African penguins (Spheniscus demersus) from Gdansk Zoo and in their sole food, Baltic herring (Clupea harengus), from Gdansk Bay. The average concentration of HBCD in whole herrin...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-014-0081-z
更新日期:2015-02-01 00:00:00
abstract::In many studies that investigate the toxic effects of pollutants on earthworms, experiments are performed using only one species of earthworms, most commonly the Eisenia species. However, the differences in sensitivities of different earthworm species could potentially lead to an underestimation of environmental aspec...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-013-9930-4
更新日期:2013-10-01 00:00:00
abstract::Heavy metals present in the soil get differently accumulated in organisms and show different rates of toxicity at different stages of the life cycle of any organism living there. To see whether such toxicants get accumulated during the embryonic development and/or change the normal developmental processes of organisms...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/pl00006613
更新日期:1999-05-01 00:00:00
abstract::Acid rain is a serious environmental problem in the world and is of a particular concern in southern China where most of the soils are acidic. This study investigated the dynamics of cations, phosphorus (P), and soil organic matter (SOM) in the Latosol (acidic red soil) from south China under the influences of simulat...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-006-0004-8
更新日期:2007-01-01 00:00:00
abstract::Within their aquatic habitats, larval amphibians are often subjected to multiple natural and anthropic stressors. Among these, predation and waterborne pollution represent two types of stressing factor that frequently co-occur. In this connection, the present laboratory study was designed to investigate the effects of...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-006-0229-6
更新日期:2007-08-01 00:00:00
abstract::The adverse effects of heavy metals (mostly Cr, Mn, Fe, Cu, Zn, and Se) on the environment were appraised by comparing fluctuating asymmetry of dental characters (molars) in Algerian mice (Mus spretus) from polluted (Oeiras) and reference (Xévora) riparian areas, in central Portugal. The size of tooth traits was shown...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s002440010279
更新日期:2001-11-01 00:00:00
abstract::Six prairie grain farmers were monitored for pesticide exposure and related adverse effects while they mixed and/or sprayed carbofuran (Furadan 480F) with ground rig application equipment to control grasshoppers in southern Alberta, Canada. Dermal exposure was estimated with Tegaderm patches placed at seventeen locati...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/BF01056087
更新日期:1990-03-01 00:00:00
abstract::Moss biomonitoring technique was applied in a heavy-metal pollution study of Croatia in 2006 when this country participated in the European moss survey for the first time. This survey was repeated in 2010, and the results are presented in this study. For this purpose, 121 moss samples were collected during summer and ...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-013-9884-6
更新日期:2013-07-01 00:00:00
abstract::The watershed approach, currently used to assess regional streams in the United States, emphasizes least-disturbed reference conditions. Consideration of extensive wadable drainage systems found in Arkansas and Mississippi deltas challenges concepts of disturbance within a landscape of historic agricultural land use. ...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-008-9136-3
更新日期:2008-10-01 00:00:00
abstract::The aim of the present project is to determine the feasibility of measuring hepatic cytochrome P4501A1 (CYP1A1) and metallothionein (MT) mRNA in fish as an integrative measurement of persistent organic pollutants (POPs) and heavy metal contamination in sediment arising in Hong Kong. Sediment samples were collected fro...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s002449910064
更新日期:2000-05-01 00:00:00
abstract::The pattern of spatial distribution of polycyclic aromatic hydrocarbons (PAHs) in seawater, sediment, and mussels, potential toxicity of different matrices, and mussel anoxic survival from six sampling sites of the Gulf of Rijeka, the Adriatic Sea, Croatia was examined. The total concentrations of 10 PAHs vary from be...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/s00244-005-0259-5
更新日期:2007-04-01 00:00:00
abstract::Eighteen lichens from a variety of habitats were treated with 4-chlorobiphenyl (4-CB). All, as determined by means of radioactive tracers, were shown to partially convert 4-CB to 4-chloro-4'-hydroxybiphenyl. Only one species (Pseudocyphellaria crocata) produced a further major metabolite not previously reported, namel...
journal_title:Archives of environmental contamination and toxicology
pub_type: 杂志文章
doi:10.1007/BF02220817
更新日期:1975-01-01 00:00:00