Blood flow-metabolic relationships are dependent on tumour size in non-small cell lung cancer: a study using quantitative contrast-enhanced computer tomography and positron emission tomography.

abstract：:Positron emission tomography (PET) has now gained a place in the management of patients with cancer, including those with Hodgkin's disease and non-Hodgkin's lymphoma. Restaging studies and those addressing the monitoring of response to treatment are especially in focus. Most of the knowledge gained has been achieved ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Visvikis D,Ell PJ

更新日期：2003-06-01 00:00:00

abstract：PURPOSE:This study was conducted to investigate whether( 18)F-fluorodeoxyglucose (FDG) uptake, quantified by positron emission tomography (PET), correlates with histological variables including tumour grade, cell proliferation, cell cycle control integrity and glucose metabolism in patients with bone and soft tissue sa...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Tateishi U,Yamaguchi U,Seki K,Terauchi T,Arai Y,Hasegawa T

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:Vascular stiffness may potentially be used as a screening tool to identify asymptomatic patients with diabetes with abnormal myocardial perfusion. The purpose of this study was therefore to determine the association between vascular stiffness, measured in term of pulse wave velocity (PWV) and augmentation index...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Roos CJ,Djaberi R,Schuijf JD,de Koning EJ,Rabelink TJ,Smit JW,Pereira AM,Al Younis I,van der Hiel B,Scholte AJ,Bax JJ,Jukema JW

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:Low sensitivity can become a major problem when very small pinholes are used in SPECT imaging. Although a larger pinhole aperture will improve the sensitivity, this will be at the cost of the spatial resolution. With a view to improving the resolution-sensitivity trade-off, this paper explores an iterative reco...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Vanhove C,Andreyev A,Defrise M,Nuyts J,Bossuyt A

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:The intra-arterial administration of 90Y microspheres is a new palliative treatment option for unresectable liver metastases. The aim of this study was to quantitatively assess changes in FDG uptake and tumour size following 90Y microsphere treatment (SIR-Spheres) using 18F-fluorodeoxyglucose (FDG) PET/CT imagi...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bienert M,McCook B,Carr BI,Geller DA,Sheetz M,Tutor C,Amesur N,Avril N

更新日期：2005-07-01 00:00:00

abstract：PURPOSE:The aim of this short communication is to outline our experience in policies and processes of a nuclear medicine service during the COVID-19 outbreak in Singapore. METHODS:We describe the key considerations of policies and processes that have been implemented in our nuclear medicine service since the first cas...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Lam WW,Loke KS,Wong WY,Ng DC

更新日期：2020-07-01 00:00:00

abstract：:This study was performed to assess the potential benefit of positron emission tomography (PET) using fluorine-18 fluorodeoxyglucose (FDG) in patients with cervical metastasis of squamous cell carcinoma from an unknown primary tumour. Eighteen patients with cervical metastasis of squamous cell carcinoma from an unknown...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Stoeckli SJ,Mosna-Firlejczyk K,Goerres GW

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:The aim of the study was to estimate normal ranges and test-retest measures for various parameters characterising dopamine metabolism from a prolonged (18)F-dopa positron emission tomography (PET) measurement using a reference tissue model and compare their value for the detection of early Parkinson's disease (...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Oehme L,Perick M,Beuthien-Baumann B,Wolz M,Storch A,Löhle M,Herting B,Langner J,van den Hoff J,Reichmann H,Kotzerke J

更新日期：2011-08-01 00:00:00

abstract：:Flow quantitation with nitrogen-13 ammonia ((13)NH(3)) and positron emission tomography (PET) is dependent on an accurate blood time-activity curve. This is conveniently derived from the PET images by drawing a region of interest in the left ventricular cavity. The blood time-activity curve obtained in this way, howev...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hove JD,Iida H,Kofoed KF,Freiberg J,Holm S,Kelbaek H

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Recurrence in glioblastoma patients often occur close to the original tumour and indicates that the current treatment is inadequate for local tumour control. In this study, we explored the feasibility of using multi-modality imaging at the time of radiotherapy planning. Specifically, we aimed to identify par...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Lundemann M,Munck Af Rosenschöld P,Muhic A,Larsen VA,Poulsen HS,Engelholm SA,Andersen FL,Kjær A,Larsson HBW,Law I,Hansen AE

更新日期：2019-03-01 00:00:00

abstract：RATIONALE:In Parkinson's disease (PD), spatial covariance analysis of 18F-FDG PET data has consistently revealed a characteristic PD-related brain pattern (PDRP). By quantifying PDRP expression on a scan-by-scan basis, this technique allows objective assessment of disease activity in individual subjects. We provide a f...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Meles SK,Renken RJ,Pagani M,Teune LK,Arnaldi D,Morbelli S,Nobili F,van Laar T,Obeso JA,Rodríguez-Oroz MC,Leenders KL

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:Although [(18)F]FDG PET can measure therapy response sooner and more accurately than morphological imaging techniques, there is still some debate as to whether [(18)F]FDG uptake really reflects changes in the viable cell fraction. In this study changes in [(18)F]FDG uptake were investigated in a lymphoma model ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Brepoels L,De Saint-Hubert M,Stroobants S,Verhoef G,Balzarini J,Mortelmans L,Mottaghy FM

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:It is a matter of controversy whether prophylactic lymph node dissection improves prognosis and survival in papillary thyroid carcinoma (PTC) patients without suspicion of lymph node metastases either clinically or on ultrasonography. It is possible that in such patients the use of lymphatic mapping and sentine...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Pelizzo MR,Rubello D,Boschin IM,Piotto A,Paggetta C,Toniato A,De Salvo GL,Giuliano A,Mariani G,Casara D

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:The aim of this series of cases is to show the aspects of ventilation/perfusion single-photon emission computed tomography combined with computed tomography (V/Q SPECT/CT) in patients hospitalized for COVID-19 pneumonia, with the worsening of respiratory symptoms raising the suspicion of a pulmonary embolism. P...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Cobes N,Guernou M,Lussato D,Queneau M,Songy B,Bonardel G,Grellier JF

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:The nucleoside analogue 3'-deoxy-3'-(18)F-fluorothymidine (FLT) has recently been introduced for imaging cell proliferation with positron emission tomography (PET). We prospectively evaluated whether FLT uptake reflects proliferative activity as indicated by the Ki-67 index in non-small cell lung cancer (NSCLC)...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Yamamoto Y,Nishiyama Y,Ishikawa S,Nakano J,Chang SS,Bandoh S,Kanaji N,Haba R,Kushida Y,Ohkawa M

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:PET has been proven to be helpful in the delineation of gross tumour volume (GTV) for external radiation therapy in several tumour entities. The aim of this study was to determine if [(11)C]choline PET could be used to localize the carcinomatous tissue within the prostate in order to specifically target this ar...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bundschuh RA,Wendl CM,Weirich G,Eiber M,Souvatzoglou M,Treiber U,Kübler H,Maurer T,Gschwend JE,Geinitz H,Grosu AL,Ziegler SI,Krause BJ

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:Radiolabelled meta-iodobenzylguanidine (mIBG), used as targeted therapy for neuroblastoma, is known to have effects on blood pressure (BP). In this study we audited BP changes in patients receiving (131)I-mIBG therapy for neuroblastoma to identify BP-related adverse events (AE) and possible predictive factors. ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kosmin MA,Bomanji JB,Cork NJ,Shankar A,Gaze MN

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:Depression is a common symptom in patients suffering from Parkinson's disease (PD) and markedly reduces their quality of life. As post-mortem studies have shown, its presence may reflect extensive cell loss in the midbrain and brainstem with imbalances in monoaminergic neurotransmitters. However, in vivo eviden...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hesse S,Meyer PM,Strecker K,Barthel H,Wegner F,Oehlwein C,Isaias IU,Schwarz J,Sabri O

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:Functional brain (99m)Tc-HMPAO single-photon emission computed tomography (SPECT) is a useful diagnostic tool for assessment of regional cerebral blood flow, particularly in dementia, cerebrovascular disease and epilepsy. Currently, the European and American Association of Nuclear Medicine Procedure Guidelines ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Thomsen G,de Nijs R,Hogh-Rasmussen E,Frokjaer V,Svarer C,Knudsen GM

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:Despite recent advances in clinical imaging modalities, differentiation of pancreatic masses remains difficult. Here, we tested the diagnostic accuracy of molecular-based imaging including 3'-deoxy-3'-[(18)F]fluorothymidine (FLT) positron emission tomography (PET) and [(18)F]fluorodeoxyglucose (FDG) PET/CT in p...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Herrmann K,Erkan M,Dobritz M,Schuster T,Siveke JT,Beer AJ,Wester HJ,Schmid RM,Friess H,Schwaiger M,Kleeff J,Buck AK

更新日期：2012-05-01 00:00:00

abstract：:The human cardiac nervous system consists of a sympathetic and a parasympathetic branch with (-)-norepinephrine and acetylcholine as the respective endogenous neurotransmitters. Dysfunction of the cardiac nervous system is implicated in various types of cardiac disease, such as heart failure, myocardial infarction and...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Langer O,Halldin C

更新日期：2002-03-01 00:00:00

abstract：INTRODUCTION:Somatostatin receptor imaging with PET is the standard of care for patients with a neuroendocrine tumour (NET). Since therapy and imaging with somatostatin analogues utilize the same receptor, current guidelines recommend withdrawing long-acting somatostatin analogues for 3-4 weeks prior to somatostatin re...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Aalbersberg EA,de Wit-van der Veen BJ,Versleijen MWJ,Saveur LJ,Valk GD,Tesselaar MET,Stokkel MPM

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:Although polyphosphonates (PPs) were introduced as bone imaging agents in nuclear medicine in the early 1970s, the mechanisms involved in their uptake still remain unclear. Suggested mechanisms range from mineral adsorption with disputed binding to the organic phase, over incorporation into the mineralisation p...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Toegel S,Hoffmann O,Wadsak W,Ettlinger D,Mien LK,Wiesner K,Nguemo J,Viernstein H,Kletter K,Dudczak R,Mitterhauser M

更新日期：2006-04-01 00:00:00

abstract：PURPOSE:Neuroinflammation is involved in neurological disorders through the activation of microglial cells. Imaging of neuroinflammation with radioligands for the translocator protein (18 kDa) (TSPO) could prove to be an attractive biomarker for disease diagnosis and therapeutic evaluation. The indoleacetamide-derived ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Chauveau F,Boutin H,Van Camp N,Thominiaux C,Hantraye P,Rivron L,Marguet F,Castel MN,Rooney T,Benavides J,Dollé F,Tavitian B

更新日期：2011-03-01 00:00:00

abstract：:Because anatomical information on fluorine-18 fluorodeoxyglucose (FDG) whole-body positron emission tomography (PET) images is limited, combination with structural imaging is often important. In principle, software co-registration of PET and computed tomography (CT) data or dual-modality imaging using a combined PET-C...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Goerres GW,Kamel E,Heidelberg TN,Schwitter MR,Burger C,von Schulthess GK

更新日期：2002-03-01 00:00:00

abstract：PURPOSE:Increasing evidence supports the value of peptide receptor radionuclide therapy (PRRT) in patients with metastatic neuroendocrine tumours (NET), but there are limited data on its specific efficacy in NET of small intestinal (midgut) origin. This study aims to define the benefit of PRRT with (177)Lu-octreotate f...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sabet A,Dautzenberg K,Haslerud T,Aouf A,Sabet A,Simon B,Mayer K,Biersack HJ,Ezziddin S

更新日期：2015-07-01 00:00:00

abstract：UNLABELLED:The aim of this study was to evaluate the feasibility of using [(18)F] 3'-deoxy-3'-fluorothymidine (FLT) positron emission tomography (PET) for the diagnosis and grading of brain tumors. METHODS:The patient population comprised 26 patients (15 males, 11 females) with brain tumors (n=18) or nontumorous lesio...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Choi SJ,Kim JS,Kim JH,Oh SJ,Lee JG,Kim CJ,Ra YS,Yeo JS,Ryu JS,Moon DH

更新日期：2005-06-01 00:00:00

abstract：AIM:This study assessed the ability of visual and quantitative 124-iodine positron emission tomography ((124)I PET) data to detect disseminated iodine-avid lung metastases (DILM) of differentiated thyroid cancer (DTC). MATERIALS AND METHODS:Using "post-therapy" 131-iodine ((131)I) whole-body scintigraphy (TxWBS) and t...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Freudenberg LS,Jentzen W,Müller SP,Bockisch A

更新日期：2008-03-01 00:00:00

abstract：PURPOSE:The molecular imaging of tumour neoangiogenesis currently represents a major field of research for the diagnostic and treatment strategy of solid tumours. Endothelial cells from tumour neovessels overexpress the alpha(v)beta(3) integrin, which selectively binds to Arg-Gly-Asp (RGD)-containing peptides. We evalu...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sancey L,Ardisson V,Riou LM,Ahmadi M,Marti-Batlle D,Boturyn D,Dumy P,Fagret D,Ghezzi C,Vuillez JP

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:The aim of this study was to develop a methodology for the comparison of pathology specimens after prostatectomy (post-S) with PET images obtained before surgery (pre-S). This method was used to evaluate the merit of (11)C-choline PET/CT for delineation of gross tumour volume (GTV) in prostate cancer (PC). MET...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Grosu AL,Weirich G,Wendl C,Prokic V,Kirste S,Geinitz H,Souvatzoglou M,Gschwend JE,Schwaiger M,Molls M,Weber WA,Treiber U,Krause BJ

更新日期：2014-12-01 00:00:00