Factors predicting efficacy of phentolamine-papaverine intracorporeal injection for treatment of erectile dysfunction in diabetic male.

Abstract:

:Thirty-three diabetic men were instructed in the use of phentolamine-papaverine injections for the treatment of erectile dysfunction over a two-year period. Of these, 12 reported a satisfactory response and 21 reported a nonsatisfactory response. The responders and the nonresponders were retrospectively studied to identify characteristics that would predict a satisfactory response. No difference was found between the two groups in the duration of diabetes, the presence of retinopathy, neuropathy, nephropathy, peripheral vascular disease, or ischemic heart disease. The utilization of insulin, the prevalence of type II diabetes, or the use of drugs which would cause impotence, did not differ between the two groups. There was no difference in the serum testosterone levels between the two groups. Age was the only predictive factor. Only 1 of 14 patients over age sixty had a satisfactory response to treatment while 11 of 19 patients under age sixty had a satisfactory response. Five of the responders and 2 of the nonresponders proceeded to penile implant surgery and reported satisfactory results. While older diabetic men may choose a trial of intracorporeal injections, they should be counselled regarding the high failure rate and alternative forms of therapy.

journal_name

Urology

journal_title

Urology

authors

Bell DS,Cutter GR,Hayne VB,Lloyd LK

doi

10.1016/0090-4295(92)90433-w

subject

Has Abstract

pub_date

1992-07-01 00:00:00

pages

36-40

issue

1

eissn

0090-4295

issn

1527-9995

pii

0090-4295(92)90433-W

journal_volume

40

pub_type

杂志文章

相关文献

UROLOGY文献大全
  • Laparoscopic ureteroneocystostomy for distal ureteral injuries.

    abstract:OBJECTIVES:To present our initial experience with laparoscopic ureteroneocystostomy in patients with traumatic disruption of the distal ureter owing to gynecologic procedures. Reconstructive laparoscopic procedures are still evolving. METHODS:Six patients with ureterovaginal fistula in whom endoscopic management had f...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2005.04.048

    authors: Modi P,Goel R,Dodiya S

    更新日期:2005-10-01 00:00:00

  • Effects of vitamin C on androgen receptor mediated actions in human prostate adenocarcinoma cell line LAPC-4.

    abstract:OBJECTIVES:To examine the effects of vitamin C (VC) on androgen receptor (AR)-mediated functions in a human prostate cancer cell line, Los Angeles prostate cancer (LAPC-4). VC is an essential dietary substance in the maintenance and preservation of vital functions in humans. However, the role of VC in prostate cancer r...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/s0090-4295(03)00136-5

    authors: Wang MH,Abreu-Delgado Y,Young CY

    更新日期:2003-07-01 00:00:00

  • Low levels of prostate-specific antigen predict long-term risk of prostate cancer: results from the Baltimore Longitudinal Study of Aging.

    abstract:OBJECTIVES:To evaluate the relationship between low prostate-specific antigen (PSA) levels that are considered normal and the long-term risk of prostate cancer. METHODS:The relative risk of, and cumulative probability of freedom from, prostate cancer by PSA level and age decade was evaluated in male participants of a ...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/s0090-4295(01)01304-8

    authors: Fang J,Metter EJ,Landis P,Chan DW,Morrell CH,Carter HB

    更新日期:2001-09-01 00:00:00

  • A prospective study of microorganisms in urine and bladder biopsies from interstitial cystitis patients and controls.

    abstract:OBJECTIVES:Interstitial cystitis (IC) is a chronic inflammatory condition of the bladder of unknown etiology. We tested the hypothesis that a microorganism would be found at higher prevalence in urine or bladder tissue from women with IC than from control women. METHODS:Urine and bladder tissue were obtained at cystos...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/0090-4295(95)80009-3

    authors: Keay S,Schwalbe RS,Trifillis AL,Lovchik JC,Jacobs S,Warren JW

    更新日期:1995-02-01 00:00:00

  • Prostate volume and pathologic prostate cancer outcomes after radical prostatectomy.

    abstract:OBJECTIVES:To more clearly elucidate the relationship between prostate volume (PV) and prostate cancer parameters. METHODS:The Urologic Oncology Database was reviewed. A total of 3460 patients had undergone radical prostatectomy from 1988 to 2006. Of these, 2600 with complete data were included in the study and were s...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2007.05.022

    authors: Pierorazio PM,Kinnaman MD,Wosnitzer MS,Benson MC,McKiernan JM,Goluboff ET

    更新日期:2007-10-01 00:00:00

  • Laparoscopic ablation of symptomatic parenchymal and peripelvic renal cysts.

    abstract:OBJECTIVES:To assess the safety and efficacy of laparoscopic ablation of symptomatic renal cysts as minimally invasive therapeutic techniques have largely supplanted open surgical intervention for the treatment of symptomatic renal cysts. METHODS:The records of 32 consecutive adult patients who underwent laparoscopic ...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/s0090-4295(01)01145-1

    authors: Roberts WW,Bluebond-Langner R,Boyle KE,Jarrett TW,Kavoussi LR

    更新日期:2001-08-01 00:00:00

  • Long-term effects of polytetrafluoroethylene injected into the rat bladder submucosa.

    abstract:OBJECTIVE:The use of polytetrafluoroethylene (PTFE) paste in the lower urinary tract for the treatment of vesicoureteral reflux or urinary incontinence is increasing. Its use remains controversial and the long-term consequence of this substance injected into the lower urinary system of humans is largely unknown. When i...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/0090-4295(94)90149-x

    authors: Noe HN,Williams RS,Causey J,Smith DP

    更新日期:1994-06-01 00:00:00

  • Noninvasive detection and prediction of bladder cancer by fluorescence in situ hybridization analysis of exfoliated urothelial cells in voided urine.

    abstract:OBJECTIVES:To investigate the clinical utility of fluorescence in situ hybridization (FISH) of voided urine in the detection of bladder cancer and the prediction of its recurrence. METHODS:FISH with centromere-specific probes for chromosomes 9 and 17 was performed to evaluate the chromosomal alterations of exfoliated ...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/s0090-4295(00)01074-8

    authors: Ishiwata S,Takahashi S,Homma Y,Tanaka Y,Kameyama S,Hosaka Y,Kitamura T

    更新日期:2001-04-01 00:00:00

  • Rho-kinase levels in testicular ischemia-reperfusion injury and effects of its inhibitor, Y-27632, on oxidative stress, spermatogenesis, and apoptosis.

    abstract:OBJECTIVE:To investigate testicular Rho-kinase levels and the effects of its inhibitor, Y-27632, on oxidative stress, spermatogenesis, and apoptosis in testicular ischemia-reperfusion rat model. METHODS:The study included 29 adult Wistar-Albino male rats weighing 150-200 g. The rats were divided into 3 groups. Group 1...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2013.11.032

    authors: Çayan S,Saylam B,Tiftik N,Ünal ND,Apa DD,Efesoy O,Çimen B,Bozlu M,Akbay E,Büyükafşar K

    更新日期:2014-03-01 00:00:00

  • Does shock wave lithotripsy of renal stones cause cardiac muscle injury? A troponin I-based study.

    abstract:OBJECTIVES:To investigate whether shock wave lithotripsy (SWL) causes cardiac muscle injury that alters the levels of troponin I plasma, a cardio-specific enzyme shown to be useful in diagnosing cardiac muscle injury because of its high specificity. METHODS:Patients treated by SWL for renal stones participated in the ...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/s0090-4295(03)00002-5

    authors: Greenstein A,Sofer M,Lidawi G,Matzkin H

    更新日期:2003-05-01 00:00:00

  • Persistent cloaca in adult with satisfactory renal function.

    abstract::A case of persistent and uncorrected cloaca in a twenty-five-year-old woman is presented. In spite of the anomaly not being corrected, no deterioration of her kidney function was noted. She is continent for both urine and stools. In addition to two uteri which were removed at different times, she has only one kidney o...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/0090-4295(83)90347-3

    authors: Dajani AM

    更新日期:1983-07-01 00:00:00

  • Balloon-wire retrieval of a migrated urethral stent in the early postoperative period.

    abstract::We report on a new endoscopic approach to the removal of a migrated urethral stent following hypospadias repair. A flexible balloon-tipped guide wire allows the effective cystoscopic retrieval of a urethral stent, suggesting potential applications to the removal of other foreign bodies in the urinary tract. ...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/S0090-4295(96)00052-0

    authors: Poppas DP,Gillis LA,Retik AB

    更新日期:1996-06-01 00:00:00

  • Vena cava tumor thrombus from renal cell carcinoma arising from adrenal vein.

    abstract::Renal cell carcinoma is a highly vascular tumor with the propensity to propagate along venous channels. Vena cava tumor thrombi are reported to occur in approximately 4-10 per cent of cases and requires modification of the standard radical nephrectomy. We report the first 3 cases of vena caval tumor thrombus emanating...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/0090-4295(84)90065-7

    authors: Crawford ED,Woodside JR,Skinner DG,Blank BH,Kiker JD

    更新日期:1984-06-01 00:00:00

  • Mass circumcision with a novel plastic clamp technique.

    abstract:OBJECTIVE:To evaluate the safety and efficacy of mass circumcision performed using a plastic clamp. METHODS:A total of 2013 males, including infants, children, adolescents, and adults were circumcised during a 7-day period by using a plastic clamp technique. Complications were analyzed retrospectively in regard to 4 d...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2010.12.018

    authors: Senel FM,Demirelli M,Pekcan H

    更新日期:2011-07-01 00:00:00

  • An original balloon-expanding urethral suture guide for radical prostatectomy.

    abstract::Between August 1991 and July 1994, an original balloon-expanding urethral suture guide (24 F) was used in 157 consecutive cases of radical retropubic prostatectomy. Both the instrument and its clinical use are described. This guide guarantees good intraoperative exposure of the sectioned urethral stump during vesical ...

    journal_title:Urology

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0090-4295(99)80274-x

    authors: Da Pozzo LF,Colombo R,Montorsi F,Guazzoni G,Rigatti P

    更新日期:1995-10-01 00:00:00

  • Segmental Testicular Infarction Associated to Torsion: First Case Report in Childhood.

    abstract::Testicular torsion in children is not uncommon emergency problem which occur due to twist in the spermatic cord leading to ischemia or infarction to testicle. Hemorrhagic infarction can occur following testicular torsion is globally; however, in extremely rare situation, such infarction can be segmental. Segmental tes...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2020.07.056

    authors: Elifranji M,Elawad A,Stafrace S,Salle JLP,Vallasciani S

    更新日期:2020-08-10 00:00:00

  • Effective radiation exposure in evaluation and follow-up of patients with urolithiasis.

    abstract:OBJECTIVE:To quantify the effective radiation dose associated with the evaluation and follow-up of patients with urolithiasis. METHODS:Retrospective review was performed for consecutive patients presenting to a tertiary stone clinic with acute stone episodes between November 2007 and December 2008, and had at least 2 ...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2011.07.1387

    authors: Fahmy NM,Elkoushy MA,Andonian S

    更新日期:2012-01-01 00:00:00

  • Radical cystectomy in patients previously treated for localized prostate cancer.

    abstract:OBJECTIVES:To present outcomes of a contemporary series of patients undergoing radical cystectomy (RC) for bladder cancer after previous treatment for localized cancer of the prostate (CaP). METHODS:A retrospective review of more than 1000 RCs performed for bladder cancer between 1995 and 2008 identified 49 patients p...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2010.01.048

    authors: Jayram G,Katz MH,Steinberg GD

    更新日期:2010-12-01 00:00:00

  • Tumor-size breakpoint for prognostic stratification of localized renal cell carcinoma.

    abstract:OBJECTIVES:To identify an optimal tumor-size breakpoint to distinguish between two groups with different prognoses in a large cohort of patients with localized renal cell carcinoma (RCC). METHODS:We reviewed the clinical records of 813 patients who had undergone surgical treatment for localized RCC from 1976 to 2000. ...

    journal_title:Urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.urology.2003.09.081

    authors: Ficarra V,Prayer-Galetti T,Novara G,Bratti E,Zanolla L,Dal Bianco M,Artibani W,Pagano F

    更新日期:2004-02-01 00:00:00

  • Benign hepatic masses mimicking metastatic renal cell carcinoma.

    abstract::Making the distinction between a benign hepatic mass and renal cell carcinoma metastatic to the liver is crucial in evaluating a patient with renal cell carcinoma. The erroneous diagnosis of metastatic renal cell carcinoma may deter the surgeon from performing a potentially curative nephrectomy. In this report, we pre...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/0090-4295(89)90405-6

    authors: Wishnow KI,Charnsangavej C,Babaian RJ

    更新日期:1989-03-01 00:00:00

  • Clinical Proof-of-concept of a Novel Platform Utilizing Biopsy-derived Live Single Cells, Phenotypic Biomarkers, and Machine Learning Toward a Precision Risk Stratification Test for Prostate Cancer Grade Groups 1 and 2 (Gleason 3 + 3 and 3 + 4).

    abstract:OBJECTIVE:To examine the ability of a novel live primary-cell phenotypic (LPCP) test to predict postsurgical adverse pathology (P-SAP) features and risk stratify patients based on SAP features in a blinded study utilizing radical prostatectomy (RP) surgical specimens. METHODS:Two hundred fifty-one men undergoing RP we...

    journal_title:Urology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.urology.2018.09.032

    authors: Albala D,Manak MS,Varsanik JS,Rashid HH,Mouraviev V,Zappala SM,Ette E,Kella N,Rieger-Christ KM,Sant GR,Chander AC

    更新日期:2019-02-01 00:00:00

  • Transurethral electrovaporization of the prostate: one-year experience.

    abstract:OBJECTIVES:To determine the safety and efficacy of transurethral electrovaporization of the prostate (TVP) in men with lower urinary tract symptoms. METHODS:A prospective trial of 114 consecutive patients who underwent TVP since August 1994 was conducted. The mean follow-up period was 12.3 months. Parameters evaluated...

    journal_title:Urology

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0090-4295(96)00487-6

    authors: Kaplan SA,Santarosa RP,Te AE

    更新日期:1996-12-01 00:00:00

  • Prognostic value of lymphovascular invasion in transitional cell carcinoma of upper urinary tract.

    abstract:OBJECTIVES:To elucidate the prognostic significance of lymphovascular invasion (LVI) in patients with upper tract transitional cell carcinoma. METHODS:Of 86 patients with upper tract transitional cell carcinoma who underwent nephroureterectomy with bladder cuff (95%) or parenchymal-sparing (5%) surgery from 1991 to 20...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2004.11.001

    authors: Hong B,Park S,Hong JH,Kim CS,Ro JY,Ahn H

    更新日期:2005-04-01 00:00:00

  • Inhibition of fatty-acid synthase suppresses P-AKT and induces apoptosis in bladder cancer.

    abstract:OBJECTIVE:To investigate the role of fatty acid synthase (FASN) in bladder transitional cell carcinoma (BTCC). METHODS:FASN expression was investigated in non-muscle-invasive BTCC tissue specimens by immunohistochemistry and BTCC cell lines by Western blot. After treatment with FASN-siRNA or FASN inhibitor cerulenin (...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2012.02.046

    authors: Jiang B,Li EH,Lu YY,Jiang Q,Cui D,Jing YF,Xia SJ

    更新日期:2012-08-01 00:00:00

  • Efficacy compared between caudal block and periprostatic local anesthesia for transrectal ultrasound-guided prostate needle biopsy.

    abstract:OBJECTIVES:To investigate the clinical efficacy of a caudal block compared with periprostatic local anesthesia for transrectal ultrasound-guided multicore prostate needle biopsy. METHODS:A total of 100 patients who had undergone initial prostate biopsy using a systematic five-region biopsy by a single operator were in...

    journal_title:Urology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.urology.2006.02.025

    authors: Horinaga M,Nakashima J,Nakanoma T

    更新日期:2006-08-01 00:00:00

  • Importance of posterolateral needle biopsies in the detection of prostate cancer.

    abstract:OBJECTIVES:To determine whether needle biopsy of the posterolateral aspects of the prostate aids in prostate cancer detection. In the routine sextant biopsy strategy, the posterolateral aspects of the prostate are not sampled. METHODS:Using an 18-gauge biopsy gun, we performed sextant biopsies and an additional nine n...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/s0090-4295(01)00979-7

    authors: Epstein JI,Walsh PC,Carter HB

    更新日期:2001-06-01 00:00:00

  • Extraction of UroLume endoprosthesis with one-stage urethral reconstruction using buccal mucosa.

    abstract::Long-term analyses of the UroLume Endoprosthesis have shown conflicting results with regard to efficacy and restricture rates. The best management of recurrent urethra stricture disease at the site of a previous UroLume stent is unknown. We describe a previously unreported technique for transperineal excision of the U...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2005.08.038

    authors: Fisher MB,Santucci RA

    更新日期:2006-02-01 00:00:00

  • Six Weeks of Fluoroquinolone Antibiotic Therapy for Patients With Elevated Serum Prostate-specific Antigen Is Not Clinically Beneficial: A Randomized Controlled Clinical Trial.

    abstract:OBJECTIVE:To evaluate asymptomatic men with elevated serum prostate-specific antigen (PSA) to determine whether a 6-week course of fluoroquinolone antibiotics lowers serum PSA and affects recommendations for prostate biopsy. MATERIALS AND METHODS:A randomized, single-center prospective trial of 150 men with an initial...

    journal_title:Urology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.urology.2015.11.046

    authors: Greiman A,Shah J,Bhavsar R,Armeson K,Caulder S,Jones R,Keane TE,Clarke HS,Savage SJ

    更新日期:2016-04-01 00:00:00

  • Some guidelines in use of lasers in renal surgery.

    abstract::Some guidelines for the use of lasers in renal surgery are presented. The carbon dioxide laser was successfully used in 9 patients with diverse renal pathology (staghorn calculus, 4 patients; renal tumor, 3 patients; congenital arteriovenous (A-V) fistula, 1 patient; segmental chronic atrophic pyelonephritis, 1 patien...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/0090-4295(87)90141-5

    authors: Rosemberg SK

    更新日期:1987-02-01 00:00:00

  • Intermittent androgen deprivation after PSA-complete response as a strategy to reduce induction of hormone-resistant prostate cancer.

    abstract:OBJECTIVES:The increasing interest in exploring the use of intermittent androgen deprivation in prostate cancer has prompted a retrospective review of patients who elected to stop treatment. METHODS:Case records were reviewed. RESULTS:Twenty patients after 3 to 48 months (median 12) of endocrine therapy elected to st...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/S0090-4295(96)00373-1

    authors: Oliver RT,Williams G,Paris AM,Blandy JP

    更新日期:1997-01-01 00:00:00