Abstract:
:We have studied 139 cases of intracranial germ cell tumours up to the beginning of 1993, 63.3% of which showed monotypic histological patterns and 36.7% were shown to be mixed tumours. All these cases underwent surgery followed by radiation and/or chemotherapy. All cases of choriocarcinoma died within 2 years. Cases of yolk sac tumour (endodermal sinus tumour) and embryonal carcinoma also showed poor results. Mature teratoma had a 5-year survival rate (5 YSR) and 10-year survival rate (10 YSR) of 92.9% each. Immature teratoma and malignant teratoma showed a 5-YSR and 10-YSR of 75.0% each. Germinoma showed a 5-YSR of 94.7% and a 10-YSR of 91.2%. All these results may bring into question the validity of the germ cell theory, since germinoma, which should be the most undifferentiated according to the theory, was the most benign and choriocarcinoma and yolk sac tumour (endodermal sinus tumour) which should be the most differentiated, were the most malignant in the follow-up study. Therefore, germ cell tumours may not originate from one single type of cells (primordial germs cells), except for germinoma. The embryonic cells of various stages of embryogenesis may perhaps be misplaced in the bilaminar embryonic disc and become involved in the stream of lateral mesoderm at the time of the primitive streak formation and be carried to the future cranial area to be wrongly enfolded into the brain at the time of the neural tube formation. The following law may be propounded: Tumours composed of cells resembling the cells appearing in the earlier stages of embryogenesis (ontogenesis) are more malignant than those resembling the cells appearing in the later stages of embryogenesis (ontogenesis).
journal_name
Br J Neurosurgjournal_title
British journal of neurosurgeryauthors
Sano Kdoi
10.1080/02688699550041395subject
Has Abstractpub_date
1995-01-01 00:00:00pages
391-401issue
3eissn
0268-8697issn
1360-046Xjournal_volume
9pub_type
杂志文章,评审abstract::Introduction: Pituitary carcinomas are poorly understood, rare entities. They are distinguished from adenomas not by histopathological features but rather by the presence of metastases.Objective: We discuss the diagnosis, mechanism of dissemination and pathogenesis based on a review of the literature and illustrated b...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1582750
更新日期:2020-10-01 00:00:00
abstract::The objective of the investigation was to report on the health-related quality of life (HRQoL) of patients diagnosed with skull base tumours using the Short Form Health Survey questionnaire (SF-36). Those patients suffering with vestibular schwannoma were examined to determine the effect facial nerve function had on t...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690120114183
更新日期:2002-02-01 00:00:00
abstract::Pial arteriovenous fistula (AVF) is a rare vascular lesion, with less than 120 reported cases in the English literatures (Hoh et al., Neurosurgery 2001;49(6):1351). The angio-architecture, clinical course and therapeutic options are all different from arteriovenous malformation (AVM), dural AVM or other intracranial v...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.3109/02688697.2011.566382
更新日期:2011-10-01 00:00:00
abstract::Background: Vertebral body compression fractures are one of the most common causes of disability and morbidity, especially among the elderly population. The present study was performed in order to evaluate the effect of percutaneous balloon kyphoplasty (BKP) on patients' pain and quality of life (QOL) in Iran.Methods:...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1777254
更新日期:2020-06-09 00:00:00
abstract::We present a case of spontaneous 79% regression in the size of a vestibular schwannoma (VS). A 41-year-old lady with a large (36 mm) vestibular schwannoma underwent serial follow-up MRI scans which demonstrated the shrinkage over 9 years; the highest relative spontaneous regression recorded in the literature for vesti...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1582749
更新日期:2019-03-04 00:00:00
abstract::Chordoid glioma, a rare tumour of the third ventricle, has distinctive histological appearances. Fewer than 20 cases have been reported in the literature, all but three in females. This paper describes a 54-year-old man with a chordoid glioma and reviews the clinicopathological features of this lesion. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/02688690120036865
更新日期:2001-04-01 00:00:00
abstract::The aim of this study was to investigate prognostic factors and the most appropriate treatment for patients with ruptured middle cerebral artery (MCA) aneurysms in relation to haematoma distribution. Ninety-two patients with ruptured MCA aneurysms, who underwent surgery during the last 11 years from 1986 to 1996, were...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699944131
更新日期:1999-02-01 00:00:00
abstract::Fibrous dysplasia (FD) is an uncommon benign fibro-osseous abnormality of bone, of unknown aetiology and equal sex incidence, which is most commonly restricted to one bone (monostotic FD: MFD, 70%). Less commonly multiple bones are affected (polyostotic FD: PFD, 27%). Vertebral involvement is uncommon (4%), but more c...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/02688690400012525
更新日期:2004-10-01 00:00:00
abstract::Until recently, warfarin, clopidogrel and aspirin have provided the mainstay for prevention of thrombotic disease in cardiac patients. However, new classes of drugs have recently emerged that promise better clinical outcomes and lower risks. Use of such agents has increased, but increased risk and severity of intra-cr...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.3109/02688697.2015.1029433
更新日期:2015-01-01 00:00:00
abstract::Purpose: To investigate the incidence and risk factors of postoperative dysphagia after anterior cervical decompression and fusion (ACDF) in terms of demographic, procedural and anaesthetic perspectives.Materials and methods: Medical records and radiologic data of patients who underwent anterior cervical surgery perfo...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1757037
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:To assess changes in neurological function after cranioplasty. METHODS:Functional and neurocognitive assessments including activities of daily living assessment, functional independence measure (FIM) and the Cognitive assessment report (COGNISTAT) were conducted on all patients within 72 h before and 7 days...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.817532
更新日期:2013-10-01 00:00:00
abstract:INTRODUCTION:Patients with cauda equina syndrome (CES) are frequently referred late when neurological damage cannot be reversed. National Guidelines for emergency referral, imaging and treatment of CES contain symptoms and/or signs that are those of late often, irreversible CES. Referral at this stage may be too late f...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/02688697.2017.1297364
更新日期:2017-06-01 00:00:00
abstract::Intracerebral haemorrhage is a devastating condition lacking effective therapies, with an uncertain role for surgery in many. Early research described an ischaemic penumbra around the haematoma, representing an area of potential therapeutic intervention. This article discusses the evidence for and against the existenc...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2011.578773
更新日期:2011-08-01 00:00:00
abstract::Several studies have demonstrated an association between arterial hypertension (AH) and an increased morbidity and mortality from both cardiovascular diseases and stroke (including subarachnoid haemorrhage, SAH). Among the functional disturbances implicated in hypertension much interest has been focused on the calcium...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699108998477
更新日期:1991-01-01 00:00:00
abstract::A subdural empyema with a Salmonella species as the likely causative organism is presented. We believe that this is the first reported case of such an infection in an HIV positive patient. The difficulties in treatment and diagnosis are discussed. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699550041818
更新日期:1995-01-01 00:00:00
abstract::Interstitial brachytherapy for recurrent gliomas normally necessitates the invasive application of a stereotactic frame by screw-fixation which must be kept on for several hours. The use of a relocatable stereotactic frame offers many advantages over conventional systems. We present our experience in 18 patients and v...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699209002371
更新日期:1992-01-01 00:00:00
abstract::We report a large trigeminal neurinoma in an 18-month-old child involving the Gasserian ganglion and all three divisions in a plexiform pattern. The tumour in the ophthalmic division extended all the way to the supraorbital nerve. The child presented with proptosis which had been observed since she was 4 months of age...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699409029629
更新日期:1994-01-01 00:00:00
abstract::Objective: To evaluate the clinical efficacy, practicability, and safety of an ultrasonic osteotome for percutaneous transforaminal endoscopic discectomy (PTED) in patients with calcified lumbar disc herniation (CLDH).Methods: A total of 25 CLDH patients who underwent PTED at our department between December 2017 and A...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1687850
更新日期:2020-02-01 00:00:00
abstract::Cytogenetic studies over many years have established absence or deletion of chromosome 22 as a common finding in meningiomas. Enormous karyotypic variation is recognised: an abnormal hyperdiploid clone can occur in a histologically benign meningioma. The cytogenetic, histopathological and macroscopic findings in 13 me...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688698909002850
更新日期:1989-01-01 00:00:00
abstract::Two patients with histologically benign pituitary adenomas subsequently underwent resections of a frontal and a cerebellar tumour each of which had histological appearances identical to those of classic pituitary adenomas. The frontal tumour was immunoreactive for prolactin, and the cerebellar metastasis was immunorea...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699550041584
更新日期:1995-04-01 00:00:00
abstract::Stereotactic radiosurgery (SRS) for brain metastases has been carried out at the Leeds Gamma Knife Centre since March 2009. The aim of this study was to examine the outcomes and toxicity in our initial cohort of patients. The medical records of patients with brain metastases referred to the Leeds Gamma Knife Centre be...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2012.690913
更新日期:2012-10-01 00:00:00
abstract::Background: Cranioplasty (CP) of autologous bone flap after decompressive craniectomy (DC) is known to be associated with a high complication rate, particularly bone flap resorption (BFR). In a retrospective study, we used a novel virtual reality (VR) visualisation technique to identify and evaluate risk factors assoc...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1661962
更新日期:2019-12-01 00:00:00
abstract::An obese woman with benign intracranial hypertension had been managed for several years with lumbo-peritoneal shunting. Following a bilopancreatic procedure performed for management of her obesity dense peritoneal adhesions caused repeated shunt failure. The shunt system was successfully converted to a lumbo-atrial sy...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690601127460
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:To explore the changes of a series of cytokines before and after percutaneous balloon kyphoplasty (PKP) and prognostic markers for response to PKP. METHODS:From 1 January 2019 to 31 May 2019, all single-level lumbar osteoporotic vertebral compression fracture (OVCF) patients diagnosed by MRI who matched the ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1823941
更新日期:2020-10-14 00:00:00
abstract::Purpose: Decompressive craniectomy (DC) is widely used to treat raised intracranial pressure (ICP) in cranial trauma and stroke. It is accompanied by numerous complications. The aim of our study is to assess the surgical treatment of infections related to the use of a dural substitute with concurrent CSF leakage perfo...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1735301
更新日期:2020-03-06 00:00:00
abstract::A 48-year-old man with a cystic craniopharyngioma developed hypersomnia, personality changes, memory impairment and thermal dysfunction following intracystic administration of bleomycin through an Ommaya reservoir after partial removal of the tumour. The patient's neurological deterioration was thought to be related t...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699409101192
更新日期:1994-01-01 00:00:00
abstract::A 33-year-old man presented with a history of fits and on initial investigation was suspected of having a left frontal parafalcine meningioma. Initial surgical procedure to excise the lesion had to be abandoned owing to the extreme vascularity of the lesion. Histology revealed it to be a haemangioendothelioma. At a se...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/02688699943123
更新日期:1999-12-01 00:00:00
abstract::We report a secretory meningioma with metastasis from a pulmonary adenocarcinoma in a 48-year-old woman. Secretory meningioma can simulate metastatic disease both clinically and pathologically. Secretory meningioma and tumour-to-tumour metastasis are each rare, and we believe this to be the first report of their coinc...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/026886902753512646
更新日期:2002-02-01 00:00:00
abstract::Sellar melanocytomas represent a small subgroup of primary melanocytic tumors arising from leptomeningeal melanocytes. They are benign, slow-growing tumors with a high risk of recurrence. We report two cases of sellar melanocytoma treated at the same institute. A 35-year-old woman presented with amenorrhea and an intr...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1667485
更新日期:2019-09-20 00:00:00
abstract::The incidence of haemorrhagic complications of intracranial pressure monitoring (ICPM) has previously been reported. However, in these studies, the techniques employed to access the inside of the cranium varied. While 3-mm essentially blind 'twistdrill' craniostomies have been used, their role has been limited for fea...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690220148897
更新日期:2002-06-01 00:00:00