Abstract：
:Rhythmic patterns in the rat's brain self-stimulation behavior were analyzed across levels of illumination, including conditions of constant illumination (LL), constant darkness (DD), and light-dark cycles (LD 12:12). LD entrainment was achieved with light intensities ranging from 0.25 to 440 lux, and little or no change was found in the phase-angle difference between the dominant spectral peak and the light transitions. Under constant conditions, the circadian period (tau) increased in proportion to illumination level, with means ranging from 24.10 h (DD) to 25.90 h (LL 440 lux). tau increased linearly as a function of long I within the range of 0.25 to 30 lux, yielding a change of 0.28 h for a 10-fold increment in illumination level, a value which closely matches Aschoff's [3] preliminary estimate of delta tau/delta ILL for the rat. The circadian spectral component was influenced by several factors. (1) Re-entrainment protocol. Given a succession of LL conditions without entrainment segments in between, circadian rhythmicity was obscured at high illumination levels. (2) Duration of LL exposure. Even following an entrainment segment, long-term LL resulted in reduced power or loss of the circadian component. (3) LD vs LL. Spectral power was consistently higher under entrainment than under corresponding LL intensities, and there was a trend toward reduced power as a function of LL intensity. A wide range of ultradian spectral components was found across conditions. Under entrainment, most such components were harmonics of the circadian fundamental; under constant conditions, the frequency relationships were relatively variable.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Terman JS,Terman Mdoi
10.1016/0166-4328(80)90005-4subject
Has Abstractpub_date
1980-12-01 00:00:00pages
507-19issue
6eissn
0166-4328issn
1872-7549pii
0166-4328(80)90005-4journal_volume
1pub_type
杂志文章abstract：:Conditioned opiate reward (COR) is rapidly acquired and slowly extinguished. The slow rate of extinction of the salience of drug-related cues contributes to drug craving and relapse. The gamma-aminobutyric acid receptor type B (GABA(B)) agonist, baclofen, attenuates the unconditioned rewarding actions of several drugs...
journal_title：Behavioural brain research
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
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pub_type： 杂志文章
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journal_title：Behavioural brain research
pub_type： 杂志文章,评审
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更新日期：1993-12-20 00:00:00
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2017.09.041
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journal_title：Behavioural brain research
pub_type： 杂志文章
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更新日期：1997-09-01 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(95)00193-x
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doi：10.1016/j.bbr.2017.01.012
更新日期：2017-03-30 00:00:00
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doi：10.1016/j.bbr.2011.04.011
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journal_title：Behavioural brain research
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doi：10.1016/j.bbr.2009.10.037
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journal_title：Behavioural brain research
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doi：10.1016/j.bbr.2013.04.050
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journal_title：Behavioural brain research
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journal_title：Behavioural brain research
pub_type： 杂志文章
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更新日期：1998-01-01 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2005.10.016
更新日期：2006-03-15 00:00:00
abstract：:Tissue plasminogen activator (tPA) is known to play physiologically and pathologically crucial roles in the central nervous system. However, it is still obscure whether it affects social behavior. We investigated social behavior and neuronal activation after social stimulation in tPA knockout (KO) mice. In a resident-...
journal_title：Behavioural brain research
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更新日期：2015-03-15 00:00:00
abstract：:Many studies have demonstrated that stressors can modify the physiological action of drugs, mainly morphine. The present study investigated the effects of a mild stressor on chloral hydrate (Chl)-induced sedation in mice. For 4 consecutive days, NaCl and Chl-treated mice (300 mg kg(-1)) were stressed (S) either by a 5...
journal_title：Behavioural brain research
pub_type： 杂志文章
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更新日期：2000-09-01 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
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更新日期：2004-03-02 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章,评审
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更新日期：2009-06-25 00:00:00
abstract：:In an eight-arm radial maze, working and reference memory can be assessed simultaneously in the fixed position of reward task (FPRT) in which half of the arms are baited and their positions are fixed throughout the training trails. We characterized performance of rats in the variable position of reward task (VPRT), in...
journal_title：Behavioural brain research
pub_type： 杂志文章
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更新日期：2002-08-21 00:00:00
abstract：:MK-801, a non-competitive NMDA-R antagonist, has been utilized in the analysis of mammalian learning and memory. The zebrafish is a novel vertebrate study species that has been proposed for the analysis of the mechanisms of learning and memory. Although learning paradigms have been developed for this species, psychoph...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2011.02.019
更新日期：2011-07-07 00:00:00
abstract：:Cholinergic dysfunction and deposition of plaques containing amyloid β-peptides (Aβ) are two of the characteristics of Alzheimer's disease. Here, we combine APPswe/PS1dE9 (APP/PS1) mice with the cholinergic immunotoxin mu p75-saporin (SAP) to integrate partial basal forebrain cholinergic degeneration and the neuropath...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2012.11.012
更新日期：2013-03-01 00:00:00
