Abstract：
:Deeper understanding of signaling mechanisms underlying bitterness perception in people is essential for designing novel and effective bitter blockers, which could enhance nutrition and compliance with orally administered bitter-tasting drugs. Here we show that variability in a human odorant-binding protein gene, OBPIIa, associates with individual differences in bitterness perception of fat (oleic acid) and of a prototypical bitter stimulus, 6-n-propylthiouracil (PROP), suggesting a novel olfactory role in the modulation of bitterness sensitivity.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Tomassini Barbarossa I,Ozdener MH,Melania,Love-Gregory L,Mitreva M,Abumrad NA,Pepino MYdoi
10.1016/j.bbr.2017.05.015subject
Has Abstractpub_date
2017-06-30 00:00:00pages
200-204eissn
0166-4328issn
1872-7549pii
S0166-4328(17)30568-5journal_volume
329pub_type
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