Drotrecogin alfa (activated) for nonmenstrual toxic shock syndrome associated with methicillin resistant Staphylococcus aureus infection.

Abstract:

:Nonmenstrual toxic shock syndrome (TSS) due to Staphylococcus aureus can lead to significant morbidity and mortality. While drotrecogin alfa (DA) has been employed in patients with Methicillin-resistant Staphylococcus aureus (MRSA) severe sepsis and septic shock, its utility in TSS remains unclear. The authors report a case of severe sepsis in the setting of MRSA-associated TSS that responded to treatment with DA. This case illustrates a potential role for DA in the treatment of toxic shock syndromes and emphasizes the importance of aggressive diagnostic and therapeutic modalities in approaching these conditions.

journal_name

South Med J

journal_title

Southern medical journal

authors

Haddadin DW,Samnani IQ,Moorman JP

doi

10.1097/01.smj.0000234646.27647.a6

subject

Has Abstract

pub_date

2006-11-01 00:00:00

pages

1295-6

issue

11

eissn

0038-4348

issn

1541-8243

journal_volume

99

pub_type

杂志文章
  • Recurrent spontaneous myoclonus in alcohol withdrawal.

    abstract::I have described two patients who had recurrent spontaneous myoclonic jerking in the alcohol withdrawal state. These movements were distinguishable clinically and electroencephalographically from partial seizures and epilepsia partialis continua. The jerking did not respond to anticonvulsants but resolved as the withd...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198308000-00028

    authors: Drake ME Jr

    更新日期:1983-08-01 00:00:00

  • Sharpening the tandem walking test for screening peripheral neuropathy.

    abstract:OBJECTIVE:Few tests of functional motor behavior are useful for rapidly screening people for lower extremity peripheral neuropathy. The goal of this study was to improve the widely used tandem walking (TW) test. METHODS:We tested "normal" (control) adult and ambulatory patients with peripheral neuropathy (PN) with the...

    journal_title:Southern medical journal

    pub_type: 临床试验,杂志文章

    doi:10.1097/SMJ.0000000000000009

    authors: Cohen HS,Mulavara AP,Peters BT,Sangi-Haghpeykar H,Kung DH,Mosier DR,Bloomberg JJ

    更新日期:2013-10-01 00:00:00

  • Cephalosporins for surgical prophylaxis: computer projections of intraoperative availability.

    abstract::Cephalosporin antibiotics are the most frequently used agents for surgical prophylaxis. Within this class are considerable pharmacokinetic variations that could have significant implications. We used a computer simulation of cephalosporin serum levels to describe concentrations achieved and maintained intraoperatively...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198508000-00018

    authors: Nix DE,DiPiro JT,Bowden TA Jr,Vallner JJ

    更新日期:1985-08-01 00:00:00

  • Disseminated intravascular coagulation in sickle cell crisis.

    abstract::We conclude that DIC can occur as a result of sickle cell crisis in the absence of sepsis and we recommend that patients with sickle cell disease, particularly those with hemoglobin SC disease, presenting in crisis should be considered at risk for the development of disseminated intravascular coagulation. With symptom...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-197904000-00043

    authors: Corvelli AI,Binder RA,Kales A

    更新日期:1979-04-01 00:00:00

  • Meropenem versus imipenem/cilastatin in the treatment of hospitalized patients with skin and soft tissue infections.

    abstract::Meropenem is a new carbapenem antibiotic shown to resist degradation by renal dehydropeptidase I. In a multicenter, open-label, prospective trial, we compared the efficacy and safety of meropenem with imipenem/cilastatin in patients with skin and soft tissue infections. Patients received either 500 mg of meropenem eve...

    journal_title:Southern medical journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/00007611-199504000-00003

    authors: Nichols RL,Smith JW,Geckler RW,Wilson SE

    更新日期:1995-04-01 00:00:00

  • Septicemia in children with cancer.

    abstract::Because of the persistently high mortality from sepsis in cancer patients, a retrospective study was designed to identify the causative organisms and to determine the factors affecting the outcome of sepsis. A total of 84 episodes of septicemia in 61 children with cancer were studied. The more frequently isolated orga...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-197902000-00007

    authors: Favor LF,Tarpay M,Blackstock R

    更新日期:1979-02-01 00:00:00

  • Cardiac rupture due to blunt trauma.

    abstract::Cardiac rupture due to blunt trauma has been recognized with increasing frequency over the past two decades. The mortality rate is high and the majority of patients die before they arrive at the emergency department. A high index of suspicion and prompt surgical intervention are crucial for survival. We report the man...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199707000-00019

    authors: Tassiopoulos AK,Carlin RE,Dibos L,McGraw DJ

    更新日期:1997-07-01 00:00:00

  • Acute intermittent porphyria with atypical neuropathy.

    abstract::The patient we have described had lower extremity numbness, paresthesias, constipation, urinary retention, and sexual dysfunction. Laboratory evaluation confirmed a diagnosis of acute intermittent porphyria (AIP). Vitamin B6 and glucose therapy initiated resolution of symptoms. The sensory neuropathy described here is...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:

    authors: Goren MB,Chen C

    更新日期:1991-05-01 00:00:00

  • Pharmacologic reduction of the risk of aspiration.

    abstract::Parameters for significant risk of aspiration have been defined as a gastric pH less than 2.5 and/or a volume greater than 25 ml. We investigated the effects of metoclopramide and cimetidine, alone and in combination, on the pH and volume of gastric contents of patients taking nothing by mouth before general anesthesi...

    journal_title:Southern medical journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00007611-198611000-00009

    authors: Gipson SL,Stovall TG,Elkins TE,Crumrine RS

    更新日期:1986-11-01 00:00:00

  • Hypogammaglobulinemia in infants infected with human immunodeficiency virus.

    abstract::Two premature infants were infected with HIV via blood transfusions during the neonatal period. Although neither patient had serum antibody to HIV owing to severe hypogammaglobulinemia, HIV infection was confirmed by finding HIV antigen in the sera of both patients. These cases show that HIV infection can produce seve...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198904000-00005

    authors: Saulsbury FT

    更新日期:1989-04-01 00:00:00

  • Cerebral monitoring during implantation of automatic internal cardiac defibrillators.

    abstract::Implantation of automatic internal cardiac defibrillators (AICD) for management of arrhythmias necessitates the induction of ventricular fibrillation (VF) to test the device adequately. The profound hypotension associated with induced arrhythmia and subsequent circulatory arrest may result in cerebral ischemia. To cha...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199305000-00009

    authors: Dorman BH,Conroy JM,Baker JD 3rd,Kratz JM,Leman RB

    更新日期:1993-05-01 00:00:00

  • Survey of major neurologic disorders in a biracial United States population: the Copiah County Study.

    abstract::To determine the prevalence of frequently occurring neurologic disorders in a biracial population, a survey of households and chronic care institutions was carried out for all residents of Copiah County, Mississippi. Along with a complete census, interviews were held using extensive questions about diagnoses, signs, a...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198703000-00016

    authors: Haerer AF,Anderson DW,Schoenberg BS

    更新日期:1987-03-01 00:00:00

  • Sports Concussion Management: part II.

    abstract::Millions of concussions occur every year in the United States. The public interest in concussion has increased after a number of high-profile deaths in high school athletes from sports-related head trauma and in some professional athletes from chronic traumatic encephalopathy. One of the most active areas of research ...

    journal_title:Southern medical journal

    pub_type: 杂志文章,评审

    doi:10.1097/SMJ.0000000000000064

    authors: Terrell TR,Cox CB,Bielak K,Casmus R,Laskowitz D,Nichols G

    更新日期:2014-02-01 00:00:00

  • Brain stem infarction due to chiropractic manipulation of the cervical spine.

    abstract::A case of brain stem infarction after chiropractic manipulation of the cervical spine is presented. Proposed mechanisms and sites of possible arterial injury are discussed. A diagnosis of vertebral artery occlusion was made using conventional brachial angiography. Digital intravenous angiography, a relatively new and ...

    journal_title:Southern medical journal

    pub_type: 杂志文章,评审

    doi:10.1097/00007611-198312000-00014

    authors: Braun IF,Pinto RS,De Filipp GJ,Lieberman A,Pasternack P,Zimmerman RD

    更新日期:1983-12-01 00:00:00

  • Massive asymmetric virginal breast hypertrophy.

    abstract::Massive unilateral virginal breast hypertrophy in a 13-year-old girl was treated by right breast reduction, with removal of 2,968 g of breast tissue. A year later, the patient had enlargement of the left breast, and contralateral reduction mammoplasty was done. Two-year follow-up has shown no further enlargement. This...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199604000-00019

    authors: Netscher DT,Mosharrafa AM,Laucirica R

    更新日期:1996-04-01 00:00:00

  • Total hip arthroplasty: review of long-term results in 185 cases.

    abstract::Review of 185 consecutive Muller total hip arthroplasties five to nine years after operation showed that 14 patients had died and that three deaths were directly related to the surgery. Of these, 37 patients (54 hips) could not be located and were excluded. Another patient, nonambulatory for an unrelated cause, was al...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:

    authors: Dunn AW

    更新日期:1982-08-01 00:00:00

  • Radiation therapy for early stage carcinoma of the glottic larynx.

    abstract::The results of radiation therapy of 79 patients with early carcinoma of the vocal cord are reported. Nine (13%) of the 69 patients with stage I disease had local recurrence, and two (20%) of the ten patients with stage II disease had local recurrence without local node metastasis. Subsequent control of radiation failu...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-197901000-00004

    authors: Kim RY,Fincher JA,Roth RE

    更新日期:1979-01-01 00:00:00

  • Current concerns for blood donor well-being and health.

    abstract::In addition to assuring an adequate and safe blood supply, blood collection agencies are responsible for the well being of donors. Several aspects of the current blood donor experience may negatively impact donor health and require modification. Physicians need to be aware of health-related issues associated with bloo...

    journal_title:Southern medical journal

    pub_type: 杂志文章,评审

    doi:10.1097/SMJ.0b013e3181d3904f

    authors: Reiss RF,Kessler D

    更新日期:2010-04-01 00:00:00

  • The digital toolbox for teaching.

    abstract::Continued improvements in computer technology have led to significant enhancement of clinical teaching. We describe a "digital toolbox" consisting of personally accessible hardware and software products to assist in clinical teaching. The areas covered are computer-assisted diagnosis, digitization and display of clini...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199512000-00003

    authors: Sandroni S,McGee J

    更新日期:1995-12-01 00:00:00

  • Cytologic screening for gynecologic cancer.

    abstract::In the past 30 years there has been no improvement in the five-year survival rate for endometrial carcinoma. Any change comparable to improved survival in cervical carcinoma will be accomplished only by similar detection of the early asymptomatic and precursor lesions of endometrial carcinoma. Reasons why the conventi...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198004000-00022

    authors: Muenzer RW,Kim K

    更新日期:1980-04-01 00:00:00

  • Pectus excavatum: a 15-year perspective.

    abstract::Pectus excavatum is relatively uncommon. Our experience with 177 children during a 15-year period produced changes in our surgical technique, which now includes a small transverse incision, minimal subcutaneous flap elevation, a muscle-relaxing incision over the fifth costal cartilage, complete resection of involved c...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199109000-00010

    authors: Golladay ES,Wagner CW

    更新日期:1991-09-01 00:00:00

  • Diabetic care: an integrated subspecialty and primary care approach.

    abstract::The University of Virginia Department of Medicine has reorganized its adult diabetic ambulatory care program to provide optimal primary care and subspecialty services. This new program, the Diabetes Consult Service of the University Medical Associates, is organized to provide primary care by a single physician in addi...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:

    authors: Pohl SL,Hodge RH Jr,Evans WS,Hodge SS,Lumelsky-Weinbaum J

    更新日期:1981-01-01 00:00:00

  • Weight loss and complications after four gastric operations for morbid obesity.

    abstract::Since April 1975, 292 patients have had gastric operations for morbid obesity: gastric bypass with Roux-en-Y gastrojejunostomy (RY), 105 patients; gastric bypass with loop gastrojejunostomy (loop), 69 patients; greater curvature gastroplasty, 40 patients; and gastric partition with gastrogastrostomy, 78 patients. Foll...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198211000-00005

    authors: Herbst CA Jr,Buckwalter JA

    更新日期:1982-11-01 00:00:00

  • Haff disease after eating salmon.

    abstract::While fish consumption is considered a component of a heart-healthy diet, many illnesses have been associated with eating contaminated fish. The authors describe two cases of muscle weakness and rhabdomyolysis that occurred after eating salmon. Cases of rhabdomyolysis and muscle weakness after consumption of fresh wat...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/SMJ.0b013e3181583673

    authors: Langley RL,Bobbitt WH 3rd

    更新日期:2007-11-01 00:00:00

  • Compliance with therapy for cervical dysplasia among women of low socioeconomic status.

    abstract::This paper reports results of a project designed to examine factors related to compliance with referral for follow-up and treatment of cervical dysplasia. Women studied had cervical dysplasia diagnosed by Pap smear between May 1989 and April 1990. These women had regular follow-up at the gynecology clinic of the Reyno...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-199201000-00003

    authors: Laedtke TW,Dignan M

    更新日期:1992-01-01 00:00:00

  • Authors' Response.

    abstract::Supplemental digital content is available in the text. ...

    journal_title:Southern medical journal

    pub_type: 评论,杂志文章

    doi:10.14423/SMJ.0000000000000716

    authors: Bob-Manuel T,Askandar S,Khouzam RN

    更新日期:2017-11-01 00:00:00

  • Mesenteric venous thrombosis and oral contraceptives.

    abstract::Reported is a case of mesenteric venous thrombosis occurring in a 46-year-old woman who had taken an oral contraceptive for six years. Seventeen cases of mesenteric venous thrombosis have been reported in young women taking oral contraceptives. An association between oral contraceptive agents and mesenteric venous thr...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-197703000-00033

    authors: Nesbit RR Jr,Deweese JA

    更新日期:1977-03-01 00:00:00

  • Opioids for chronic nonterminal pain.

    abstract::This article first reviews the evidence for and against chronic opioid therapy. Evidence supporting the opioid responsiveness of chronic pain, including neuropathic pain, includes multiple randomized trials conducted over months (up to 8 months). Observational studies are conducted for longer, and many also support op...

    journal_title:Southern medical journal

    pub_type: 杂志文章,评审

    doi:10.1097/01.smj.0000223946.19256.17

    authors: Ballantyne JC

    更新日期:2006-11-01 00:00:00

  • Pyarthrosis simulating ruptured rotator cuff syndrome.

    abstract::A 50-year-old black man was admitted with a diagnosis of a ruptured rotator cuff syndrome two weeks after an injury to the right shoulder and treatment by intra-articular steroid injection. At operation pus and necrotic debris were found in the shoulder joint, but the rotator cuff was anatomically intact. Surgical deb...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198206000-00037

    authors: Gordon EJ,Hutchful GA

    更新日期:1982-06-01 00:00:00

  • Barium appendicitis.

    abstract::We report a case of acute appendicitis with perforation associated with retained appendiceal barium. Abnormally retained barium may lead to appendicitis and this should be kept in mind when a barium-filled appendix is seen in an asymptomatic patient. Routine follow-up films on all patients whose appendix fills with ba...

    journal_title:Southern medical journal

    pub_type: 杂志文章

    doi:10.1097/00007611-198204000-00037

    authors: Sisley JF,Wagner CW

    更新日期:1982-04-01 00:00:00