Abstract:
:Parameters for significant risk of aspiration have been defined as a gastric pH less than 2.5 and/or a volume greater than 25 ml. We investigated the effects of metoclopramide and cimetidine, alone and in combination, on the pH and volume of gastric contents of patients taking nothing by mouth before general anesthesia. We divided 40 young women having gynecologic surgery into four groups: control subjects (group 1), those given metoclopramide (group 2), those given cimetidine (group 3), and those given both drugs (group 4). Injections were given 45 to 90 minutes before induction of general anesthesia, and no other premedicant was allowed. When the mean pH and volume of gastric contents were measured, the patients given both drugs had a mean pH of 6.9 and a mean volume of 2.0 ml. The control group showed significant risk for aspiration in terms of both volume and pH. Use of metoclopramide alone reduced the risk related to volume, and cimetidine alone reduced the risk related to pH. The most striking effects were achieved by the combination of the two agents, which produced a relatively narrow range of "safe" pH and volume.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Gipson SL,Stovall TG,Elkins TE,Crumrine RSdoi
10.1097/00007611-198611000-00009subject
Has Abstractpub_date
1986-11-01 00:00:00pages
1356-8issue
11eissn
0038-4348issn
1541-8243journal_volume
79pub_type
临床试验,杂志文章,随机对照试验abstract::The temporary tissue expander can generate an excess of full-thickness skin that can be recruited into an adjacent area of tissue deficiency caused by scar contracture. The creation of a pseudobursa enhances the functional improvement gained by this technique. Now in its developmental stage, tissue expansion carries a...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198604000-00011
更新日期:1986-04-01 00:00:00
abstract::I reviewed factors contributing to diagnostic delay in 12 children who had symptoms of meningitis for more than three days before diagnosis. Prior antibiotic therapy was more common in children with delayed diagnosis. Parental factors included possible neglect in one child and passivity and failure to recognize the se...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198409000-00014
更新日期:1984-09-01 00:00:00
abstract::Bile acid sequestrants (BAS) continue to command a position in the treatment of dyslipidemias 25 years after their introduction. Partial diversion of the enterohepatic circulation using BAS depletes the endogenous bile acid pool by approximately 40%, thus stimulating an increase in bile acid synthesis from cholesterol...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.smj.0000208120.73327.db
更新日期:2006-03-01 00:00:00
abstract::Only in relatively recent years has the role of dietary fiber, once thought to be an unnecessary and even undesirable by-product, begun to be appreciated in the maintenance of health. Research now indicates that a deficiency of fiber in the modern western diet may contribute to a host of diseases. Inadequate dietary f...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198610000-00003
更新日期:1986-10-01 00:00:00
abstract::Granular cell tumors (GCT) are rare, usually benign neoplasms of Schwann cell origin. Since discovery in 1926, fewer than 80 cases of GCT involving the lung have been reported. This report presents a 45-year-old male who presented with symptoms consistent with chronic pancreatitis associated with night sweats, weight ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000182134.44098.01
更新日期:2005-10-01 00:00:00
abstract::A large number of drugs can induce pulmonary disease. We report the case of a female patient who was receiving cyproterone acetate for severe hirsutism. After 4 months of cyproterone therapy, she had dyspnea, pulmonary infiltrates, and a restrictive ventilatory defect. Bronchoalveolar lavage showed CD8+ lymphocytosis ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199710000-00016
更新日期:1997-10-01 00:00:00
abstract::I reviewed the cases of 50 consecutive patients who had a total of 75 plastic surgery procedures after weight reduction. The average weight loss was 126 lb. There were 28 women and 22 men. The 75 operations were abdominoplasty (24), face-lift (18), reduction mammaplasty (ten), blepharoplasty (eight), mastopexy (eight)...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198711000-00011
更新日期:1987-11-01 00:00:00
abstract::A woman developed anterior uveitis at age 24, inflammatory bowel disease at age 29, and ankylosing spondylitis at age 45 by history. There were frequent recurrences. An HLA-B27 test was positive at age 53. The literature indicates that all of these conditions together in a HLA-B27-positive woman are uncommon. Physicia...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.smj.0000215747.80424.2d
更新日期:2006-05-01 00:00:00
abstract::Children with sickle cell anemia who were less than 5 years old were observed over a three-year period. Those born to recent Haitian immigrants accounted for 108.4 patient-years. They had seven episodes of Streptococcus pneumoniae bacteremia and five due to Haemophilus influenzae for rates of 6.5 and 4.6 episodes per ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198907000-00009
更新日期:1989-07-01 00:00:00
abstract::Keloid management remains controversial, and recurrence and untoward side effects limit the use of many techniques. During a seven-year period, I surgically treated 19 children, aged 3 to 17 (mean 10.5 years), with a total of 28 keloids. After aseptic skin preparation, the interface between the keloid and normal skin ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198806000-00013
更新日期:1988-06-01 00:00:00
abstract::Agenesis of the gallbladder is a rare anomaly believed to be an organogenetic failure. This is the third instance of familial agenesis of the gallbladder reported in the literature. The diagnosis of agenesis of the gallbladder can only be made during exploratory celiotomy and must be confirmed by an intraoperative nee...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197704000-00041
更新日期:1977-04-01 00:00:00
abstract::Several treatment regimens of trimethoprim-sulfamethoxazole (TMP-SMZ) were compared to the USPHS-recommended schedules for treatment of uncomplicated gonorrhea with ampicillin plus probenecid, tetracycline, or aqueous procaine penicillin G in both men and women. TMP-SMZ, six tablets as a single oral dose daily for 3 d...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197509000-00020
更新日期:1975-09-01 00:00:00
abstract::The results of radiation therapy of 79 patients with early carcinoma of the vocal cord are reported. Nine (13%) of the 69 patients with stage I disease had local recurrence, and two (20%) of the ten patients with stage II disease had local recurrence without local node metastasis. Subsequent control of radiation failu...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197901000-00004
更新日期:1979-01-01 00:00:00
abstract::To determine sensitivity and specificity of magnetic resonance imaging (MRI) and ultrasonography (US) in the detection of breast implant rupture, and also to determine the relative merits of clinical examination and mammography, we studied 81 patients (160 implants). All patients had implants removed, thus allowing co...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199604000-00009
更新日期:1996-04-01 00:00:00
abstract::Septic arthritis is a serious and sometimes fatal complication of rheumatoid arthritis. We have examined the clinical characteristics of 16 patients with infectious arthritis seen during an eight-year period. This represented 0.5% of all admissions to our hospital for patients with rheumatoid arthritis. Although rheum...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198610000-00011
更新日期:1986-10-01 00:00:00
abstract::An increased risk of skin and lymphoreticular malignancies is well documented in renal transplant patients receiving long-term immunosuppressive therapy, but squamous cell carcinoma of the esophagus is rare. We have reported the first case in the English literature in which there is a strong association between long-t...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198712000-00025
更新日期:1987-12-01 00:00:00
abstract::One hundred fifty-seven pregnancies complicated by different degrees of diabetes, toxemia, and hypertension were studied with serial urinary placental estrogen determinations. A simple and fast method for total placental estrogen determination was used. The level of total estrogen excretion was related to Apgar score ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197510000-00009
更新日期:1975-10-01 00:00:00
abstract:BACKGROUND:Recent studies on the impact of rib fractures after blunt trauma have shown a linear relationship between age, increasing number of rib fractures, and complications, including mortality. Others have documented that age-related morbidity increases before age 65 in trauma patients. We hypothesize that patients...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000203815.29757.d3
更新日期:2006-04-01 00:00:00
abstract::Myelolipomas are benign tumors composed of an admixture of mature adipose tissue and normal hematopoietic cells. The vast majority occur within the adrenal glands, but several extra-adrenal myelolipomas (EAMLs) have been reported. The typical EAML is a solitary, well-defined mass within the abdomen, most commonly in t...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199506000-00008
更新日期:1995-06-01 00:00:00
abstract:BACKGROUND:Surveys in recent years show that office emergencies are likely to occur in pediatric offices and that most offices are not equipped to deal with these situations. METHODS:To determine the pediatrician's preparedness to manage emergencies, we surveyed a randomly selected sample of 240 office-based pediatric...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199808000-00008
更新日期:1998-08-01 00:00:00
abstract::Liver cysts are a well-recognized feature of autosomal dominant polycystic kidney disease (ADPKD) and occur in 77% of patients more than 60 years old. Serious sequelae, however, are rare, the two most common complications being pain and cyst infections. Portal hypertension has been reported in ADPKD due to the rare pr...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199906000-00015
更新日期:1999-06-01 00:00:00
abstract::Arsenic poisonings occur in Mississippi despite public education campaigns to prevent poisonings in the home. We reviewed 44 Mississippi cases of arsenic exposures occurring from January 1986 to May 1990. We compared the epidemiologic differences between unintentional and intentional poisonings. Cases were found and c...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199104000-00012
更新日期:1991-04-01 00:00:00
abstract::The gene for sickle cell disease is carried by 8% of the African-American population in the United States. The primary care physician is often called upon to recognize and treat one of the major sequelae of sickle cell disease--vaso-occlusive pain crisis. An injectable nonsteroidal anti-inflammatory drug has recently ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199208000-00005
更新日期:1992-08-01 00:00:00
abstract::Psychiatric hospital services for adolescents have steadily increased in recent years and great interest has been generated in determining treatment outcome. In this study, 74 adolescent inpatients completed structured telephone interviews one year after discharge. The questions probed school, job, and family adjustme...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198009000-00013
更新日期:1980-09-01 00:00:00
abstract::The University of Virginia Department of Medicine has reorganized its adult diabetic ambulatory care program to provide optimal primary care and subspecialty services. This new program, the Diabetes Consult Service of the University Medical Associates, is organized to provide primary care by a single physician in addi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::Atypical facial pain or neuralgia and lower-half headache are confusing terms and should be discarded. Recurrent unilateral, throbbing, frontal headaches should be referred to as facial migraine. Patients whose trigeminal branches have been subjected to repeated surgical procedures and who have relentless unilateral f...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198207000-00012
更新日期:1982-07-01 00:00:00
abstract::Autoimmune neutropenia (AIN) is defined as a neutrophil count <1.5 × 109/L caused by increased peripheral destruction of neutrophils from an underlying autoimmune mechanism in which autoantibodies are directed against a patient's own neutrophils. AIN has a multifactorial etiology ranging from an idiopathic primary phe...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.14423/SMJ.0000000000000637
更新日期:2017-04-01 00:00:00
abstract::Schwannoma arising within breast parenchyma is rare. We report such a case in a 50-year-old woman. The tumor, which measured 7 mm, is the smallest and the only mammographically detected schwannoma of the breast thus far reported. Clinicians should be aware that this benign tumor of breast may simulate a malignant neop...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199602000-00018
更新日期:1996-02-01 00:00:00
abstract::Like all types of farming, raising tobacco has many hazards that may lead to injury, disability, or death. Burley tobacco farming is a multistep process that is not highly mechanized. An 8-year emergency department surveillance system in Kentucky identified 674 injury cases related to the production of burley tobacco....
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVE:No standard therapeutic option exists for men with prostate cancer who have failed local therapy, have no gross metastatic disease, and whose only manifestation of disease is a rising prostate-specific antigen (PSA) level. Soy products are able to affect PSA kinetics in some men with prostate cancer, and this...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3182335151
更新日期:2011-11-01 00:00:00