Abstract:
INTRODUCTION:The aim of this prospective study is to determine the relationship between the pathologic characteristics of the transitional cell carcinoma (TCC) of the bladder and prostatic involvement. MATERIALS AND METHODS:Sixty men with bladder TCC underwent standard radical cystoprostatectomy and were enrolled in this study. Vascular and perineural invasion, maximum diameter of the tumor, presence of carcinoma in situ, distance between the tumor and the bladder neck, and grade and local stage of the tumor were recorded and their relation with prostatic involvement was studied. In addition, hydronephrosis and age of the patients were included in the analysis. RESULTS:The mean age of the patients was 63.9 +/- 11.1 years. Of 60 men included in this study, 15 patients were found to have prostatic involvement with TCC (25%). Univariate statistical analyses showed that vascular invasion and the distance between the tumor and the bladder neck were significantly related to the prostatic involvement (P = .007; P < .001). But, in the logistic regression, only the distance between the tumor and the bladder neck was significantly related to the prostatic involvement (P = .001). CONCLUSION:This study suggests that the probability of prostatic involvement in patients with bladder TCC tumors near the bladder neck is high. Prostate-sparing or capsule-sparing cystectomy should be avoided in such patients.
journal_name
Urol Jjournal_title
Urology journalauthors
Tabibi A,Simforoosh N,Parvin M,Abadpour B,Abdi H,Khafri Ssubject
Has Abstractpub_date
2006-07-01 00:00:00pages
145-9issue
3eissn
1735-1308issn
1735-546Xpii
186/184journal_volume
3pub_type
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