Validity of Neutrophil Gelatinase Associated Lipocaline as a Biomarker for Diagnosis of Children with Acute Pyelonephritis.

Abstract:

PURPOSE:Novel biomarkers have been investigated for various renal disorders, including urinary tract infection (UTI). The aim of this study was to assess whether urine neutrophil gelatinase associated lipocaline (NGAL), could represent a reliable biomarker for diagnosis and treatment of children with acute pyelonephritis (APN). MATERIALS AND METHODS:A total of 37 children (32 females, 5 males) with APN were included in this prospective study. Urine NGAL was measured before and 5-7 days after antibiotic treatment in the UTI group, using ELISA kit and compared with 26 (8 females, 18 males) control group children admitted for other bacterial infections. RESULTS:Mean age of the UTI group was 39 ± 28 months, compared to 43.6 ± 31.5 months for the control group with no statistically significant difference. Median urine NGAL level was significantly higher in patients with APN than the other subjects [0.48 (interquartile range (IQR): 0.15-0.72) vs. 0.065 (0.01-0.24), P = .001], and decreased significantly after antibiotic treatment (P = .002). Using a cutoff of 0.20 ng/mL, sensitivity and specificity of urine NGAL were 76% and 77% for prediction of APN, respectively. The area under the ROC curve (AUC) for urine NGAL was 0.75 (CI= 0.61-0.88), suggesting urine NGAL as a relatively good predictive biomarker of APN. CONCLUSION:Urine NGAL is a good biomarker for diagnosis and treatment monitoring of APN in children. .

journal_name

Urol J

journal_title

Urology journal

authors

Nickavar A,Safaeian B,Valavi E,Moradpour F

subject

Has Abstract

pub_date

2016-10-10 00:00:00

pages

2860-2863

issue

5

eissn

1735-1308

issn

1735-546X

pii

3523

journal_volume

13

pub_type

杂志文章
  • Comparing absorbable and nonabsorbable sutures in corporeal plication for treatment of congenital penile curvature.

    abstract:PURPOSE:To compare the outcome of corporeal plication using absorbable versus nonabsorbable sutures for the treatment of congenital penile curvature. MATERIALS AND METHODS:Thirty-eight men older than 15 years old with congenital penile curvature were enrolled in the study. Patients were randomly divided into two equal...

    journal_title:Urology journal

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Basiri A,Sarhangnejad R,Ghahestani SM,Radfar MH

    更新日期:2011-10-01 00:00:00

  • Comparison of open and laparoscopic varicocelectomies in terms of operative time, sperm parameters, and complications.

    abstract:INTRODUCTION:Varicocele is one of the most common causes of infertility. In this study, we evaluated and compared the operative time, sperm analysis results, and complications of three different methods of open and laparoscopic varicocelectomies. MATERIALS AND METHODS:From among all bilateral varicocelectomies in our ...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Shamsa A,Mohammadi L,Abolbashari M,Shakeri MT,Shamsa S

    更新日期:2009-07-01 00:00:00

  • Surgical Treatment of Erectile Dysfunction and Peyronie's Disease Using Malleable Prosthesis.

    abstract:PURPOSE:Peyronie's disease (PD) is a condition of middle aged men and frequently accompanied by erectile dysfunction (ED) which was attributed to penile deformity, vascular pathology and psychological components. The implantation of semi-rigid penile prosthesis allows for these patients to undergo a simple procedure ai...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Yavuz U,Ciftci S,Ustuner M,Yilmaz H,Culha M

    更新日期:2015-12-23 00:00:00

  • Effect of saffron on semen parameters of infertile men.

    abstract:INTRODUCTION:We conducted this study to determine the effects of saffron (Crocus sativus) on the results of semen analysis in men with idiopathic infertility. MATERIALS AND METHODS:In this clinical trial, 52 nonsmoker infertile men whose problem could not be solved surgically were enrolled. They were treated by saffro...

    journal_title:Urology journal

    pub_type: 临床试验,杂志文章

    doi:

    authors: Heidary M,Vahhabi S,Reza Nejadi J,Delfan B,Birjandi M,Kaviani H,Givrad S

    更新日期:2008-10-01 00:00:00

  • Laparoscopic bilateral retroperitoneal lymph node dissection in stage II testis cancer.

    abstract:PURPOSE:We report our experience with laparoscopic bilateral retroperitoneal lymph node dissection (RPLND) in 4 patients with stage II testis cancer. MATERIALS AND METHODS:Between January 2002 and January 2009, 4 patients with stage II testis cancer underwent laparoscopic bilateral RPLND. In 2 patients, laparoscopic b...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Basiri A,Asl-Zare M,Sichani MM,Djaladat H

    更新日期:2010-07-01 00:00:00

  • Arterial stiffness in kidney transplant recipients: an overview of methodology and applications.

    abstract:INTRODUCTION:Cardiovascular disease is still a major cause of mortality in kidney transplant patients. This is partially attributed to the nonclassic cardiovascular risk factors including arterial stiffness, an established independent predictor of mortality in several patient populations. MATERIALS AND METHODS:An exte...

    journal_title:Urology journal

    pub_type: 杂志文章,评审

    doi:

    authors: Khoshdel AR,Carney SL

    更新日期:2008-01-01 00:00:00

  • Urological Services in the Era of COVID-19.

    abstract:INTRODUCTION:On 11 March 2020, the World Health Organization (WHO) declared a pandemic. Since then hospitals have reduced inpatient and outpatient workflow and cancelled or suspended all non-emergent and routine surgical procedures. Our objective is to determine whether, during the COVID-19 period, there has been any m...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:10.22037/uj.v16i7.6330

    authors: Efthimiou I

    更新日期:2020-07-22 00:00:00

  • Urogenital history in veterans exposed to high-dose sulfur mustard: a preliminary study of self-reported data.

    abstract:INTRODUCTION:To date, little information exists regarding urogenital diseases in those who have been exposed to sulfur mustard (SM). We report the self-reported history of urologic conditions and findings on physical examination in a group of male veterans 19 to 26 years after exposed to high-dose sulfur mustard. MATE...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Soroush MR,Ghanei M,Assari S,Khoddami Vishteh HR

    更新日期:2009-04-01 00:00:00

  • Effect of smoking on prognostic factors of transitional cell carcinoma of the bladder.

    abstract:PURPOSE:This study was conducted to evaluate the effects of smoking on the clinical characteristics and growth trend of transitional cell carcinoma (TCC) of the bladder. MATERIALS AND METHODS:In a retrospective case-control study from February 2000 to March 2003, patients with TCC of bladder, referred to our clinic, w...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Mohseni MG,Zand S,Aghamir SM

    更新日期:2004-10-01 00:00:00

  • Mesothelioma in Situ of the Spermatic Cord Arising from a Patent Processus Vaginalis: A Case Report.

    abstract::Mesothelioma is an aggressive tumor originating from mesothelial cells. Mesothelioma of the spermatic cord is a very rare disease, and the most common presentation of this disease is that of aggressive mesothelioma with no description of mesothelioma in situ. We report an extremely rare case of mesothelioma in situ of...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:10.22037/uj.v16i7.5421

    authors: Kobayashi Y,Yasuhara Y,Arai H,Honda M,Hiramatsu M,Goya S

    更新日期:2020-07-30 00:00:00

  • Risk Factors Associated with Chronic Kidney Disease In Infants With Posterior Urethral Valve: A Single Center Study of 110 Patients Managed By Valve Ablation And Bladder Neck Incision.

    abstract:PURPOSE:Concurrent valve ablation and bladder neck incision is suggested as an effective and safe treatment approach in posterior urethral valve children with prominent bladder neck. We evaluated chronic kidney disease risk factors in these children. MATERIALS AND METHODS:We retrospectively reviewed medical records of...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:10.22037/uj.v16i7.6038

    authors: Amirzargar H,Shahab E,Ghahestani S,Hekmati P,Arshadi H

    更新日期:2020-09-23 00:00:00

  • Trans-Obturator Approach and the Native Tissue in the treatment of High Stage Prolapse of the Anterior Vaginal Wall: Midterm Results of a New Surgical Technique.

    abstract:PURPOSE:Pelvic organ prolapse is a common condition  as a consequence of the pelvic floor support weakness. This study evaluated the clinical results of treating the high stage prolapse of the anterior vaginal wall using a trans-obturator approach and the native vaginal wall tissue. METHODS:This was a prospective anal...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:10.22037/uj.v0i0.5619

    authors: Sharifiaghdas F

    更新日期:2020-06-18 00:00:00

  • Evaluation of the Results and Complications of Transabdominal Preperitoneal Laparoscopic Inguinal Hernia Repair in Patients with a History of Radical Prostatectomy.

    abstract:PURPOSE:Radical prostatectomy is one of the most common urological surgeries. Inguinal hernia is a well-known complication of radical prostatectomy. There are many controversies about selection of surgical techniques for repair of inguinal hernia. Traditionally laparoscopic approach was contraindicated for patients wit...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:10.22037/uj.v0i0.4751

    authors: Izadpanahi MH,Milasi R

    更新日期:2020-01-26 00:00:00

  • Comparison of different autogenous graft materials for reconstruction of large segment vas deferens defect: experimental study in rat.

    abstract:PURPOSE:Vasectomy is one of the most common urological operations performed, and provides permanent contraception. Many vasectomized men ultimately seek vasectomy reversal because of unforeseen changes in lifestyle. Vasovasostomy has varying rates of success. In this study, we utilize vas deferens (VD), artery, and vei...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Nasir S,Soyupek S,Altuntas S,Konas E,Roach EC,Özorak A,Bircan S

    更新日期:2014-05-06 00:00:00

  • Capsulotomy for treatment of compartment syndrome in patients with post extracorporeal shock wave lithotripsy renal hematomas: safe and effective, but also advisable?

    abstract:PURPOSE:To examine whether surgical decompression of hematomas by capsulotomy can help to improve long-term renal function following extracorporeal shock wave lithotripsy (SWL). MATERIALS AND METHODS:This study retrospectively identified 7 patients who underwent capsulotomy for post SWL renal hematomas between 2008 an...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Al Ghazal A,Schnoeller TJ,Baechle C,Steinestel J,Jentzmik F,Steffens S,Hirning C,Schrader M,Schrader AJ

    更新日期:2014-07-08 00:00:00

  • Postoperative Progress after Stone Removal Following Treatment for Obstructive Acute Pyelonephritis Associated with Urinary Tract Calculi: A Retrospective Study.

    abstract:PURPOSE:We aimed to identify the prevalence and risk factors of three outcomes after stone removal following treatment for obstructive acute pyelonephritis (APN) associated with urinary tract calculi: immediate postoperative febrile urinary tract infection (UTI), stone recurrence, and APN recurrence during the follow-u...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:10.22037/uj.v0i0.4847

    authors: Yamashita S,Kohjimoto Y,Higuchi M,Ueda Y,Iguchi T,Hara I

    更新日期:2020-03-16 00:00:00

  • Is modified retroperitoneal lymph node dissection alive for clinical stage I non-seminomatous germ cell testicular tumor?

    abstract:PURPOSE:To evaluate efficacy of modified retroperitoneal lymph node dissection (RPLND) in the management of patients with pathological stage (PS) I non-seminomatous germ cell testicular tumor (NSGCT) in a retrospective study. MATERIALS AND METHODS:Between April 2002 and April 2012, 55 patients with clinical stage (CS)...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Basiri A,Ghaed MA,Simforoosh N,Tabibi A,Danesh A,Nouralizadeh A,Parizi MK

    更新日期:2013-04-01 00:00:00

  • Does age affect outcomes of percutaneous nephrolithotomy?

    abstract:INTRODUCTION:The present study aimed to assess the efficacy and safety of percutaneous nephrolithotomy (PCNL) in elderly patients. MATERIALS AND METHODS:We retrospectively reviewed 50 PCNLs performed in the elderly patients (age > 65 years) carried out in our clinic from 2001 through 2007 and compared those with 248 P...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Karami H,Mazloomfard MM,Golshan A,Rahjoo T,Javanmard B

    更新日期:2010-01-01 00:00:00

  • Bladder tissue engineering using biocompatible nanofibrous electrospun constructs: feasibility and safety investigation.

    abstract:PURPOSE:To investigate the feasibility and safety of using biocompatible, nanofibrous electrospun polycaprolactone (PCL) and combination of polylactic acid (PLLA) and PCL mats in a canine model. MATERIALS AND METHODS:Plasma-treated electrospun unseeded mats were implanted in three dogs. The first dog was sacrificed af...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Shakhssalim N,Dehghan MM,Moghadasali R,Soltani MH,Shabani I,Soleimani M

    更新日期:2012-01-01 00:00:00

  • Is positron emission tomography reliable to predict post-chemotherapy retroperitoneal lymph node involvement in advanced germ cell tumors of the testis?

    abstract:PURPOSE:To evaluate if 18 fluorodeoxyglucose positron emission tomography (18FDG-PET) scan could identify post-chemotherapy retroperitoneal lymph node (RPLN) involvement in advanced germ cell tumors of the testis. MATERIALS AND METHODS:Between January 2005 and January 2009, 16 patients with advanced germ cell tumors o...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Akbulut Z,Canda AE,Atmaca AF,Caglayan A,Asil E,Balbay MD

    更新日期:2011-04-01 00:00:00

  • Living Unrelated Versus Related Kidney Transplantation: A 25-Year Experience with 3716 Cases.

    abstract:PURPOSE:To evaluate the results of transplantation from living unrelated donors (LURD) versus living related donors (LRD) with a long term follow-up of 25-30 years. MATERIALS AND METHODS:From 1984 to 2015, a total of3716 kidney transplantations (411 LRDs and 3305 LURDs) were enrolled to the study. Long-term survival o...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Simforoosh N,Basiri A,Tabibi A,Javanmard B,Kashi AH,Soltani MH,Obeid K

    更新日期:2016-03-05 00:00:00

  • Transcutaneous ultrasound guided nephrolithotomy: the first report from Iran.

    abstract:PURPOSE:To evaluate the safety and efficacy of transcutaneous ultrasound guided nephrolithotomy. MATERIALS AND METHODS:From December 1999 to December 2000, 12 patients with renal stone were selected for PCNL. Six patients had failed ESWL and the remainder had multiple and large stones in pelvis and lower calyx. Ultras...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Etemadian M,Amjadi M,Simforoosh N

    更新日期:2004-04-01 00:00:00

  • Correlation of sperm nuclear chromatin condensation staining method with semen parameters and sperm functional tests in patients with spinal cord injury, varicocele, and idiopathic infertility.

    abstract:INTRODUCTION:Our aim was to investigate sperm nuclear chromatin condensation and its correlation with semen parameters and vitality test in infertile patients with spinal cord injury (SCI), varicocele, and idiopathic infertility. MATERIALS AND METHODS:Sperm chromatin condensation was determined by aniline blue stainin...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Salsabili N,Mehrsai A,Jalalizadeh B,Pourmand G,Jalaie S

    更新日期:2006-01-01 00:00:00

  • Factors Predicting Prostate Specific Antigen Failure Following Radical Prostatectomy: Experience with 961 Patients.

    abstract:OBJECTIVE:To determine disease-related predictors for the occurrence of prostate specific antigen (PSA) failure in Iranian prostate cancer patients who underwent radical prostatectomy. METHODS:In this cohort study, we enrolled eligible patients with prostate cancer who underwent radical prostatectomy at our center bet...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:10.22037/uj.v0i0.5670

    authors: Simforoosh N,Dadpour M,Mousapour P,Shafiee A,Bonakdar Hashemi M

    更新日期:2020-01-04 00:00:00

  • Management of Large Proximal Ureteral Calculi: A Three-year Multicenter Experience of Simultaneous Supine Percutaneous Nephrolithotomy and Retrograde Ureterolithotripsy.

    abstract:PURPOSE:To share our multicenter experience using a safe and effective method for treating large proximal ure-teral calculus by simultaneous supine percutaneous nephrolithotomy (sPCNL) and retrograde ureterolithotripsy (URSL) in the Galdakao-modified supine Valdivia position. MATERIALS AND METHODS:Between December 201...

    journal_title:Urology journal

    pub_type: 杂志文章,多中心研究

    doi:10.22037/uj.v0i0.4328

    authors: Chen YC,Chen HW,Juan YS,Lo IS,Shih MP,Wu WJ,Jhan JH,Huang TY

    更新日期:2019-10-21 00:00:00

  • Orchidopexy for retractile testes in infertile men: a prospective clinical study.

    abstract:INTRODUCTION:Retractile testis may affect testicular parenchyma and spermatogenesis, and surgical treatment has been recommended for infertile men with retractile testes. We evaluated outcomes of orchidopexy in men with idiopathic infertility who suffered from bilateral retractile testes. MATERIALS AND METHODS:We perf...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Dadfar MR

    更新日期:2007-07-01 00:00:00

  • The assessment of thiol status in children with neurogenic bladder caused by meningomyelocele.

    abstract:PURPOSE:Oxidative stress can cause tissue damage in many diseases. Oxidative status depends on the balance between total oxygen radical absorbance capacity and antioxidants. Neurogenic bladder (NB) is a special state where oxidative status can influence urinary tract function. We decided to measure antioxidant (thiol) ...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Korzeniecka Kozerska A,Zawada BO,Skutnik JM,Wasilewska A

    更新日期:2014-05-06 00:00:00

  • The comparison between human leukocyte antigen system incidence in patients with bladder cancer and normal controls.

    abstract:PURPOSE:To determine the frequency of human leukocyte antigen (HLA)-B5 in patients with bladder cancer compared with normal population. MATERIALS AND METHODS:In this cross sectional study, from November 2009 until November 2010, 35 patients with pathologic diagnosis of bladder cancer who referred to urology clinic of ...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Falahatkar S,Donyamali H,Joafshani MA,Shahrokhi Damavand R,Hoda S,Esmaeili S,Gholamjani Moghaddam K,Nikpour S

    更新日期:2014-01-04 00:00:00

  • Determination of the Safe Surgical Margin for T1b Renal Cell Carcinoma.

    abstract:PURPOSE:To determine the rational surgical margin for pathological T1b renal cell carcinoma (RCC). MATERIALS AND METHODS:This retrospective study included surveys of 60 patients with T1bN0M0 RCC who underwentradical nephrectomy (RN, n = 40) or partial nephrectomy (PN, n = 20) between October 2008 and December2014 at t...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:

    authors: Zhang K,Xie WL

    更新日期:2017-01-18 00:00:00

  • Sexual Dysfunction in Premenopausal Women With Obstructive Sleep Apnea.

    abstract:PURPOSE:Sexual functions in the males with obstructive sleep apnea syndrome (OSAS) have been well investigated in the literature; however sexual functions in the premenopausal women with OSAS have been studied to a lesser extent. MATERIALS AND METHODS:The study included 22 premenopausal women diagnosed as OSAS by the ...

    journal_title:Urology journal

    pub_type: 杂志文章

    doi:10.22037/uj.v14i6.3891

    authors: Yilmaz Z,Sirinocak PB,Voyvoda B,Ozcan L

    更新日期:2017-11-04 00:00:00