Prospective study of antibiotic protocols for managing surgical site infections in children.

Abstract:

PURPOSE:We adopted antibiotic (Ab) protocols for managing surgical site infections in children and assessed their effectiveness. METHODS:We used our protocols on 1313 children between 2004 and 2005. All wounds were monitored for 30 days and classified as clean, clean-contaminated, contaminated, or dirty-infected. Infections were defined as superficial, deep, or organ/space. A retrospective study involving 721 children who had surgery in 2003 was also performed. Chi2 statistical analysis was performed. RESULTS:Postprotocol, all Abs were administered accurately by anesthesiologists and infections developed in only 22 cases (1.7%): 0.2% (clean), 2.6% (clean-contaminated), 5.8% (contaminated), and 20.8% (dirty-infected), respectively; 21 were superficial or deep and 1 was organ/space. Age at surgery and sex did not influence incidence, neither did length of surgery for clean-contaminated, contaminated, and dirty-infected wounds; clean wounds were excluded because all surgery was minor. Overall, incidence of infections was 1.2% for elective surgery and 4.5% for emergency surgery (P < .01). Preprotocol, only 67% had Ab and infections developed in 27 cases (3.7%), which is significantly higher than in postprotocol (P < .01). CONCLUSIONS:Accurate administration of Ab and careful supervision by an infection control team appear to be effective for preventing wound infections in children.

journal_name

J Pediatr Surg

authors

Ichikawa S,Ishihara M,Okazaki T,Warabi K,Kato Y,Hori S,Lane GJ,Hiramatsu K,Inada E,Kobayashi H,Yamataka A

doi

10.1016/j.jpedsurg.2007.01.034

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

1002-7; discussion 1007

issue

6

eissn

0022-3468

issn

1531-5037

pii

S0022-3468(07)00066-8

journal_volume

42

pub_type

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