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Arterial elasticity measurement in renal transplant recipients.

Abstract：

:Arterial distensibility is reduced in chronic kidney disease (CKD) and after kidney transplantation. Pulse counter analysis provides an assessment of compliance or elasticity of the large conduit arteries (C1) and small arteries (C2). Decreased compliance has been shown to be predictive of primary coronary events in CKD patients. The aim of the present study was to compare elasticity measurements in hemodialysis (HD) patients, renal transplant recipients (RTR), and healthy subjects whose coronary angiographies were without lesion. Twenty-three RTRs, 18 HD patients, and 20 healthy subjects were included in the study. Pulse wave analysis was used to determine large and small vessel compliances. The C1 and C2 levels were significantly lower in HD patients compared with recipients and healthy subjects. Recipients showed lower C2 level compared with healthy subjects. There was no difference in C1 and C2 measurements between recipients receiving tacrolimus versus cyclosporine. Transplantation improves large and to some extend small artery elasticities in CKD patients.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Yildiz A,Fazlioglu M,Ersoy A,Gullulu M,Gullulu S,Yurtkuran M

doi

10.1016/j.transproceed.2007.03.070

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

1455-7

issue

5

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(07)00447-2

journal_volume

39

pub_type

杂志文章

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