Ethical issues in clinical trials.

Abstract:

:The oncology nurse may assume many different roles in clinical trials, including direct care provider, educator, advocate, data collector, primary investigator, and member of the IRB. Regardless of the role, the nurse is in a key position to promote the interests of the individual subject as well as helping to assure that the clinical trial is conducted with scientific and ethical integrity. The nurse can help to assure that the subject is adequately informed and facilitate rational decision making. The nurse can also assure that the requirements of the protocol are consistently attended to and that subjects are well monitored and data precisely collected. "In oncology, perhaps more than in any other medical specialty, there is a blurring of the distinction between research, therapeutic innovation, and medical practice. The frontiers of knowledge in cancer are continuously advancing. The final step in the process of procuring usable knowledge is the clinical trial, a meeting place of the practice of medicine and clinical research. Because of this there are many ethical considerations which must be attended to in the justification of and conduct of a clinical trial.

journal_name

Semin Oncol Nurs

authors

Grady C

doi

10.1016/0749-2081(91)90068-z

subject

Has Abstract

pub_date

1991-11-01 00:00:00

pages

288-96

issue

4

eissn

0749-2081

issn

1878-3449

pii

0749-2081(91)90068-Z

journal_volume

7

pub_type

杂志文章
  • Adult Acute Lymphoblastic Leukemia: Treatment and Management Updates.

    abstract:OBJECTIVE:To present an overview of novel therapies for the treatment of adult acute lymphoblastic leukemia and to discuss nursing implications for these new therapies. DATA SOURCES:Published manuscripts, Web sites, and pharmaceutical package inserts. CONCLUSION:Several promising therapies have emerged in the treatme...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/j.soncn.2019.150951

    authors: Gregory S

    更新日期:2019-12-01 00:00:00

  • Risk assessment and early detection of skin cancers.

    abstract:OBJECTIVES:To describe a systematic method for skin cancer assessment, applying current standard practices for integration into nursing practice. To provide the fundamentals of performing a skin cancer assessment for the nonmelanoma skin cancers, basal cell carcinoma, and squamous cell carcinomas, and melanoma. Include...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1053/sonu.2003.50003

    authors: Maguire-Eisen M

    更新日期:2003-02-01 00:00:00

  • Impact of a parent's cancer on adult children: role and relationship issues.

    abstract::The diagnosis and initial treatment of a parent for cancer is a highly stressful process that generates a variety of concerns for adult children. This study describes the initial effect of a parent's cancer on adult children. Adult children's concerns about role and relationship issues emerged as major themes in the c...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章

    doi:10.1016/s0749-2081(05)80105-6

    authors: Germino BB,Funk SG

    更新日期:1993-05-01 00:00:00

  • Preventing cancer by controlling youth tobacco use.

    abstract:OBJECTIVES:To review the epidemiology and prevention of teen smoking and the risks of smoking among survivors of childhood cancer. DATA SOURCES:Research articles, government reports, and surveys. CONCLUSION:Nicotine dependence often begins with the first few cigarettes smoked during adolescence. Teen tobacco use is f...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1053/j.soncn.2003.08.003

    authors: DiFranza JR,Wellman RJ

    更新日期:2003-11-01 00:00:00

  • Informational needs of individuals and families with hereditary cancers.

    abstract::Individuals and families with hereditary cancers have informational needs that differ, depending on the availability of testing for increased hereditary risk and major focus of concern (reproductive decision-making or risk to self). Cancer risk counseling helps individuals understand risk information so they can make ...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章

    doi:10.1016/0749-2081(92)90042-2

    authors: Kelly PT

    更新日期:1992-11-01 00:00:00

  • Publishing in Oncology Nursing: A Look to the Past, Present, and Future.

    abstract:OBJECTIVES:To review trends and issues in publishing and provide resources on publishing opportunities for oncology nurses. DATA SOURCES:Journal articles, publishers' information for authors, online publishing resources, discussions with journal and textbook editors, personal experience. CONCLUSION:Advances in oncolo...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/j.soncn.2018.09.001

    authors: Schulmeister L

    更新日期:2018-11-01 00:00:00

  • Neurosurgical management of patients with central nervous system malignancies.

    abstract:OBJECTIVES:To provide an introduction to and description of the neurosurgical technologies used for the diagnosis and treatment of central nervous system (CNS) malignancies. DATA SOURCES:Published articles, books, and other reference materials. CONCLUSIONS:Recent advances in the development of assessment tools and su...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/s0749-2081(98)80038-7

    authors: Bohan EM

    更新日期:1998-02-01 00:00:00

  • Biology of cancer: current issues and future prospects.

    abstract::The future of cancer treatment is limited only by the rate of progress made in understanding the biology of cancer. The future will present a considerable challenge to health care professionals to learn new theories, understand new terms, and expect different toxicities. The explosion of information and technology is ...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/0749-2081(92)90009-r

    authors: Jenkins J

    更新日期:1992-02-01 00:00:00

  • Wilms' tumor: a paradigm, a parallel, and a puzzle.

    abstract::Wilms' tumor, a childhood tumor of the kidney, parallels retinoblastoma in several ways. Both malignancies occur in the very young, involve paired organs, arise from embryonal cells, can develop unilaterally or bilaterally, and can occur in hereditary and non-hereditary forms. However, Wilms' tumor rarely occurs in fa...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/0749-2081(92)90036-3

    authors: Ruccione KS

    更新日期:1992-11-01 00:00:00

  • Skin cancer preventive behavior and sun protection recommendations.

    abstract:OBJECTIVES:To summarize, in tabular form, the current literature and information available for skin cancer preventive behaviors and sun protection recommendations. DATA SOURCES:Peer-reviewed literature, web sites of professional and federal organizations. CONCLUSION:The link between skin cancer and ultra-violet radia...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章

    doi:10.1016/j.soncn.2013.06.008

    authors: Cooley JH,Quale LM

    更新日期:2013-08-01 00:00:00

  • Pathophysiology, signs, and symptoms of acute tumor lysis syndrome.

    abstract:OBJECTIVES:To provide a review of the pathophysiology and corresponding signs and symptoms of tumor lysis syndrome (TLS); to review clinical and laboratory monitoring parameters. DATA SOURCES:Primary and tertiary literature and clinical experience. CONCLUSIONS:An understanding of the pathophysiology of TLS, meticulou...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/s0749-2081(02)80100-0

    authors: Kaplow R

    更新日期:2002-08-01 00:00:00

  • Nursing care of the blood cell transplant recipient.

    abstract:OBJECTIVES:To review the complications of blood cell transplantation (BCT) and their clinical and nursing management. DATA SOURCES:Review articles, research studies, book chapters pertaining to the complications of peripheral stem cell transplantation and the management of these complications. CONCLUSIONS:As the numb...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/s0749-2081(97)80033-2

    authors: Buchsel PC,Leum E,Randolph SR

    更新日期:1997-08-01 00:00:00

  • Coping strategies and interventions for cognitive changes in patients with cancer.

    abstract:OBJECTIVES:To provide a comprehensive summary of the coping strategies and evidence-based interventions used to address cognitive impairment following cancer and cancer treatment. DATA SOURCES:Review and synthesis of empirical articles. CONCLUSION:Survivors identified a structured environment and validation of their ...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章

    doi:10.1016/j.soncn.2013.08.009

    authors: Von Ah D,Storey S,Jansen CE,Allen DH

    更新日期:2013-11-01 00:00:00

  • Interprofessional Collaboration: The Future of Publishing in Oncology.

    abstract:OBJECTIVES:To explore avenues for establishing or expanding interprofessional (IP) collaboration, to provide guidance on authoring IP oncology publications, and to highlight platforms for IP publishing. DATA SOURCES:Journal articles, organizational guidelines, panel reports, and personal experience. CONCLUSION:As hea...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/j.soncn.2018.09.010

    authors: Karlin S,Olson E,Robert A,Koppi N

    更新日期:2018-11-01 00:00:00

  • Professional patient navigation in head and neck cancer.

    abstract:OBJECTIVES:To discuss professional cancer navigation roles, models, implementation process and outcomes of patients and families dealing with head and neck cancers. One specific research is presented as an illustration. DATA SOURCES:Published scientific papers, research review articles, implementations studies. CONCL...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/j.soncn.2009.05.004

    authors: Fillion L,de Serres M,Cook S,Goupil RL,Bairati I,Doll R

    更新日期:2009-08-01 00:00:00

  • Oncology nurse navigators and the continuum of cancer care.

    abstract:OBJECTIVES:To discuss the role and challenges of the oncology nurse navigator working within a multidisciplinary team caring for patients with various types of cancers. DATA SOURCES:Published empirical research and critical analysis articles. CONCLUSION:The experienced oncology nurse in the role of navigator has the ...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/j.soncn.2013.02.005

    authors: McMullen L

    更新日期:2013-05-01 00:00:00

  • Multi-media support for informed/shared decision-making before and after a cancer diagnosis.

    abstract:OBJECTIVES:To define and distinguish informed decision-making (IDM) from shared decision-making (SDM) and review the evidence for technology-based interventions designed to facilitate informed decisions about cancer screening and treatment. DATA SOURCES:Peer-reviewed research articles from Medline and other data sourc...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章

    doi:10.1016/j.soncn.2011.04.004

    authors: Allen JD,Berry DL

    更新日期:2011-08-01 00:00:00

  • Living with bodily changes in hormone-refractory prostate cancer.

    abstract:OBJECTIVES:To review the current knowledge on living with bodily changes in hormone refractory prostate cancer (HRPC), treatment options, and common symptoms, and suggestions for improving our understanding of the experience of HRPC. DATA SOURCE:Existing literature, research, and clinical experience. CONCLUSION:Allev...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/j.soncn.2011.07.009

    authors: Lindqvist O

    更新日期:2011-11-01 00:00:00

  • Standardized nursing vocabularies: a foundation for quality care.

    abstract:OBJECTIVES:To describe the importance of standardized nursing vocabularies as a foundation for quality in health care decision-making. DATA SOURCES:Literature, online sources, and committee documents. CONCLUSIONS:Several standardized vocabularies are recognized by the American Nurses Association Committee for Nursing...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1053/sonu.2001.20415

    authors: Elfrink V,Bakken S,Coenen A,McNeil B,Bickford C

    更新日期:2001-02-01 00:00:00

  • Targeted therapies: a nursing perspective.

    abstract:OBJECTIVES:To review the development of targeted therapies and the biology of relevant therapeutic targets. To analyze the relevance of targeted agents as part of current clinical practice. DATA SOURCES:Research articles. CONCLUSION:Several targeted agents are now available for clinical use. Their mechanisms of actio...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/j.soncn.2006.01.009

    authors: Kay P

    更新日期:2006-02-01 00:00:00

  • Principles of cancer prevention.

    abstract:OBJECTIVE:To summarize the scientific principles underlying cancer prevention. DATA SOURCES:Articles, text books, personal communications, and experience. CONCLUSION:The scientific basis of cancer prevention is complex and involves experimental and epidemiologic approaches and clinical trials. IMPLICATIONS FOR NURSI...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/j.soncn.2005.06.002

    authors: Meyskens FL Jr,Tully P

    更新日期:2005-11-01 00:00:00

  • Prostate Cancer Screening.

    abstract:OBJECTIVE:To review the current state of prostate cancer screening and future directions. DATA SOURCES:Nursing, medical and scientific literature related to prostate cancer screening, and national and international professional recommendations. CONCLUSION:Prostate cancer screening has been a topic of robust discussio...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/j.soncn.2017.02.003

    authors: Dunn MW

    更新日期:2017-05-01 00:00:00

  • The Future of LGBT Cancer Care: Practice and Research Implications.

    abstract:OBJECTIVES:To synthesize state of the knowledge collected in this volume and propose future directions for lesbian, gay, bisexual and transgender (LGBT) cancer practice, education, research, and advocacy. DATA SOURCES:Current and extant literature. CONCLUSION:Health care disparities that are known but not yet fully e...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/j.soncn.2017.12.007

    authors: Rice D,Schabath MB

    更新日期:2018-02-01 00:00:00

  • Energy therapies in oncology nursing.

    abstract:OBJECTIVES:To review the published research related to the interventions of Reiki, Therapeutic Touch, and Healing Touch representing energy therapies in relation to oncology nursing. DATA SOURCES:Peer-reviewed literature. CONCLUSION:There is growing evidence that energy therapies have a positive effect on symptoms as...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/j.soncn.2011.11.006

    authors: Coakley AB,Barron AM

    更新日期:2012-02-01 00:00:00

  • Clinical dilemmas: vascular access devices.

    abstract:OBJECTIVES:To present an overview of clinical dilemmas regarding maintenance care and managing complications of vascular access devices (VADs). DATA SOURCES:Current research and published literature. CONCLUSION:The use of VADs has increased over the past three decades because they have proven to be an effective and c...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/j.soncn.2007.05.008

    authors: Camp-Sorrell D

    更新日期:2007-08-01 00:00:00

  • Cancer and the Immune System: The History and Background of Immunotherapy.

    abstract:OBJECTIVE:This article will outline the link between the immune system and cancer, and provide a historical timeline of immunotherapy developmental milestones. DATA SOURCES:Published data and peer reviewed publications/manuscripts, and textbook chapters. CONCLUSION:Science has provided a greater understanding of the ...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/j.soncn.2019.08.002

    authors: Abbott M,Ustoyev Y

    更新日期:2019-10-01 00:00:00

  • Regulatory barriers to pain management.

    abstract:OBJECTIVES:To provide an overview of relevant federal and state policies, as well as recommendations for identifying and addressing barriers to the treatment of cancer and non-cancer pain. DATA SOURCES:Review of federal and state statutes and medical board guidelines. CONCLUSIONS:There has been an increase in pain-re...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/s0749-2081(98)80022-3

    authors: Joranson DE,Gilson AM

    更新日期:1998-05-01 00:00:00

  • Guidelines for the recurrence of pediatric cancer.

    abstract:OBJECTIVES:To provide practice guidelines to assist patients and parents in coping with a return of disease. DATA SOURCES:Delphi studies, review, and research articles. CONCLUSIONS:When a child's cancer recurs, the patient and parents are at risk of physical and psychologic difficulties. Guidelines to assist patients...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章

    doi:10.1053/sonu.2002.30045

    authors: Hinds PS,Birenbaum LK,Pedrosa AM,Pedrosa F

    更新日期:2002-02-01 00:00:00

  • Efforts to recruit the economically disadvantaged to national clinical trials.

    abstract::Clinical trials are vital for the development of state-of-the-art cancer prevention and treatment. A goal for trial recruitment should be to have a representative sample of the total population by gender, race, culture, ethnicity, and socioeconomic status as appropriate. Increased sensitivity to the unique barriers an...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/s0749-2081(05)80066-x

    authors: McCabe MS,Varricchio CG,Padberg RM

    更新日期:1994-05-01 00:00:00

  • Perspectives on cancer patient education.

    abstract:OBJECTIVES:To provide an overview on cancer patient education. DATA SOURCES:Literature related to demographic and health care trends, patient education, health literacy, and cancer patient information needs. CONCLUSIONS:Cancer patients need information related to diagnosis, treatment, side effects, self-care needs, a...

    journal_title:Seminars in oncology nursing

    pub_type: 杂志文章,评审

    doi:10.1016/s0749-2081(00)80007-8

    authors: Treacy JT,Mayer DK

    更新日期:2000-02-01 00:00:00