Abstract：
:1. The convulsive effects of leptazol in the rat are potentiated by prior treatment with dexamphetamine.2. An intact dopamine synthesis is necessary for the potentiation of the convulsive action of leptazol.3. An intact noradrenaline synthesis is not necessary for this action of amphetamine, as long as the dopamine synthesis is intact.4. An intact 5-hydroxytryptamine synthesis is not necessary for the potentiation to be shown.5. Blockade of either noradrenaline, dopamine or 5-hydroxytryptamine synthesis has no direct effect on leptazol convulsions.6. It is possible that it is an intact 3-4 dihydroxyphenylalanine (dopa) synthesis rather than an intact dopamine synthesis that is involved.
journal_name
Br J Pharmacoljournal_title
British journal of pharmacologyauthors
Spencer PS,Turner TAdoi
10.1111/j.1476-5381.1969.tb09526.xsubject
Has Abstractpub_date
1969-09-01 00:00:00pages
94-103issue
1eissn
0007-1188issn
1476-5381journal_volume
37pub_type
杂志文章abstract：:1. Electroconvulsive treatment (ECT) of rabbits produced ocular inflammation consisting of conjunctival hyperaemia, miosis and protein extravasation into the aqueous humour, reflected by the so-called aqueous flare response (AFR): the maximal reduction in pupil size was 3.8 +/- 0.1 mm (s.e. of mean, n = 16) while the ...
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