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Monoamine oxidase and aldehyde dehydrogenase activity in the striatum of rats after 6-hydroxydopamine lesion of the nigrostriatal pathway.

Abstract：

:Monoamine oxidase and aldehyde dehydrogenase activity were significantly reduced in the striatum of rats 8 days after lesion of the nigrostriatal nerve pathway caused by 6-hydroxydopamine. Evidence is presented for the existence of an intraneuronal 'dopamine monoamine oxidase' and intraneuronal aldehyde dehydrogenase. Dopamine concentrations were reduced to 10% of their control values.

journal_name

Br J Pharmacol

journal_title

British journal of pharmacology

authors

Agid Y,Javoy F,Youdim MB

doi

10.1111/j.1476-5381.1973.tb08238.x

subject

Has Abstract

pub_date

1973-05-01 00:00:00

pages

175-8

issue

1

eissn

0007-1188

issn

1476-5381

journal_volume

48

pub_type

杂志文章

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