[The effect of recombinant human erythropoietin on thrombocyte aggregation capacity and on the blood prostanoid level in patients with chronic kidney failure on hemodialysis].

Abstract:

:Overall 16 patients with chronic renal failure on regular hemodialysis were examined. Of these, 8 received recombinant human erythropoietin (rhERP). A study was made of platelet aggregation and the level of some prostanoids in the blood of these patients. As the time of the treatment with rhERP was increased, the hemodialyzed patients demonstrated a tendency toward a rise of platelet aggregation induced by thrombin together with an increase of the content of PGF2 alpha, TxB2, in some cases of 6-keto-PGF1 alpha and a lowering of plasma PGE [correction of RGE] level. The data concerning activation of the synthesis of arachidonic acid metabolites (PGF2 alpha and TxB2) that enhance platelet aggregation on prolonged use of rhERP suggest the role these substances may play in the mechanism of the development of thrombotic complications in the given patients' category.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Rud'ko IA,Pokrovskiĭ IuA,Ermolenko VM,Kubatiev AA

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

128-30

issue

10

eissn

0040-3660

issn

2309-5342

journal_volume

63

pub_type

杂志文章
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  • [A trial of the long-term use of Sedacorone (amiodarone) under polyclinic conditions for the prevention of paroxysms of atrial fibrillation].

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    doi:

    authors: Bart BIa,Mamtsev BN,Larin VG,Smirnova OL

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  • [The specific features of left cardiac cavity remodeling in patients with chronic obstructive pulmonary disease and chronic cor pulmonale].

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    doi:

    authors: Strutynskiĭ AV,Bakaev RG,Glazunov AB,Banzeliuk EN,Moshkova NK,Reĭsner AA,Shavurdina SV,Vinogradova DV

    更新日期:2010-01-01 00:00:00

  • [Nitric-oxidergic mechanisms in the regulation of the bronchi and their significance in the pathogenesis of bronchial asthma].

    abstract:AIM:Assessment of NO-synthase (NOS) activity in bronchial asthma (BA) basing on cytochemical identification and quantitation of NADPN-diaphorase. MATERIALS AND METHODS:Operative samples from 12 BA patients and biopsies from 8 patients free of bronchial inflammation or obstruction. Experimental data on control and BA r...

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    pub_type: 杂志文章

    doi:

    authors: Nevzorova VA,Eliseeva EV,Zuga MV,Protopopova MIu,Gel'tser BI

    更新日期:1998-01-01 00:00:00

  • [The role of local factors regulating vascular blood flow in the development of hypoxia of the gastric mucosa in peptic ulcer].

    abstract::In 50 patients with gastric ulcer indices of oxygen tension (pO2) levels were investigated in correlation with the concentration of prostaglandins (E and F2 alpha), prostacyclin, thromboxane as well as with values of transmucous difference of potentials in different parts of the gastric mucosa, they were compared with...

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    pub_type: 杂志文章

    doi:

    authors: Pasechnikov VD,Ermolaeva NIu,Virganskiĭ AO

    更新日期:1988-01-01 00:00:00

  • [The indications for the suppression of adrenal hyperfunction in a progressive course of hypertension].

    abstract::The authors analyze the results of the surgical treatment of patients with progressive essential hypertension (PEN). The treatment involved cryodestruction (adrenalectomy) of the right adrenal and autotransplantation of the left adrenal on the vascular peduncle into the transverse mesentery. Before the operation the d...

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    pub_type: 杂志文章

    doi:

    authors: Kogan AS,Kulikov LK,Lagerev LM,Meshkov NS,Nepomniashchikh VA

    更新日期:1990-01-01 00:00:00

  • [Circular disorders in the common carotid artery bed and associated psychovegetative and hemodynamic disturbances in hypertensive patients].

    abstract:AIM:To specify circulatory disorders in the bed of common carotid artery (CCA) in hypertensive patients and these disorders influence on psychovegetative and hemodynamic disturbances. MATERIAL AND METHODS:Ultrasonic dopplerography of the region of common carotid artery, ECG, examinations of central hemodynamics, veget...

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    pub_type: 杂志文章

    doi:

    authors: Shpak LV,Kolbasnikov SV

    更新日期:2001-01-01 00:00:00

  • [Paramagnetic centers of some biological media in cholecystitis patients].

    abstract:AIM:To study paramagnetic centers (PMC) of some biological media in cholecystitis patients. MATERIALS AND METHODS:PMC of 81 patients with chronic acalculous cholecystitis and 29 patients with acute calculous cholecystitis were examined using 3-cm radiospectrometer "Rubin" employing low-temperature fixation of biologic...

    journal_title:Terapevticheskii arkhiv

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    doi:

    authors: Saĭfutdinov RG,Shcherbakova AV

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  • [The efficacy of high-intensity laser irradiation in the combined treatment of patients with esophageal candidiasis].

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    doi:

    authors: Preobrazhenskiĭ VN,Kasatkin NN

    更新日期:1996-01-01 00:00:00

  • [Effects of endotheline and nitric oxide on vascular tonicity in patients with chronic cardiac failure].

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    doi:

    authors: Denisov EN,Kots IaI,Bakhtiiarov RZ,Gumanova NG

    更新日期:2007-01-01 00:00:00

  • [Clinical significance of reciprocal changes in the ECG in acute myocardial infarction].

    abstract::A total of 206 patients with acute myocardial infarction marked by infarction localization in the anterior and inferior walls were examined. It is revealed that reciprocal changes, namely the depression of the ST segment are of prognostic significance in the assessment of the clinical course of the disease, with the S...

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    doi:

    authors: Charchoglian RA,Golikov AP,Zingerman LS,Levshunov SP

    更新日期:1989-01-01 00:00:00

  • [Interrelations of genetic markers (HLA antigens and haptoglobin variants) and the course of fibrous-cavernous pulmonary tuberculosis].

    abstract::Altogether 72 patients with different variants of a course of fibrous-cavernous pulmonary tuberculosis were investigated for the presence of HLA antigens and Hp phenotypes. It was shown that an increase in the frequency of antigen DR2 and Hp 2-2 could be used as a prognostic prerequisite in the assessment of a course ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Sadykov AS,Pospelov LE

    更新日期:1988-01-01 00:00:00

  • [Efficacy of one combined inhaled drug in the treatment of patients with bronchial asthma depending on the disease duration].

    abstract:AIM:To assess an effect of long-term administration of one combined inhaled drug containing glucocorticosteroids (GCS) and long-acting beta2-agonists (LABA) on patient compliance. MATERIAL AND METHODS:The trial included 47 patients (14 males and 33 females, mean age 48.8 +/- 13.2 years) with bronchial asthma (BA) of d...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Ovcharenko SI,Akulova MN

    更新日期:2009-01-01 00:00:00

  • [Experience in using Prolia in patients with postmenopausal osteoporosis in clinical practice].

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    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

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  • [The effect of hemosorption on the glycoprotein concentration of the blood serum in inflammatory diseases of the large intestine].

    abstract::71 patients with nonspecific diseases of the colon were examined before and after hemosorption for concentrations of seromucoid, orosomucoid, immunoglobulins G,M,A, C3 and C4 complement component fractions, haptoglobin, ceruloplasmin, alpha 1-antitrypsin, C-reactive protein, properdin, transferrin. It was found that h...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Ivanov AF,Eroshkina TD,Fomin SA,Musin II,Chirkin VV

    更新日期:1995-01-01 00:00:00

  • [An evaluation of the prognostic significance of antigen CD95(Fas/APO-1) expression on the cells of patients with a myelodysplastic syndrome, acute myeloid leukemia and chronic myeloleukemia].

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    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Polosukhina ER,Kuznetsov SV,Logcheva NP,Zabotina TN,Tenuta MR,Shirin AD,Kaletin GI,Turkina AG,Tsvetaeva NV,Shishkin IuV,Kadagidze ZG,Khoroshko ND,Volkova MA,Baryshnikov AIu

    更新日期:1998-01-01 00:00:00

  • [Errors in the diagnosis of tuberculosis of the respiratory organs in a pulmonological hospital and the possibilities of their prevention].

    abstract::Respiratory tuberculosis in a pulmonary inpatient setting is not rare but, as a rule, is not diagnosed in time. Tuberculosis-directed alertness, especially in patients with an atypical lingering course of disease, the absence of the effect of nonspecific antibacterial therapy, risk factors (immunodeficiency state, dia...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Daniliak IG,Rostislavina OA,Solomakhina NI

    更新日期:1988-01-01 00:00:00

  • [Structural-functional alterations in the heart affecting dynamics of transmitral blood flow during a hemodialysis session].

    abstract:AIM:To study dynamics of transmitral circulation (TMC) during a hemodialysis (HD) session in patients with chronic renal failure (CRF) regarding structural-functional alterations of the heart and baseline condition of the diastolic function of left ventricular (LV) myocardium. MATERIAL AND METHODS:Sixty one patients (...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Shutov AM,Edigarov OM,Mastykov VE

    更新日期:2006-01-01 00:00:00

  • [Orthostatic hypotension in primary amyloidosis].

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    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Lapin VV,Baĭkov VV,Kodzaev IuK,Amineva KhK

    更新日期:1988-01-01 00:00:00

  • [Effectiveness of antiinflammatory therapy in patients with interstitial lung diseases using re-assay of biomarker mucin 3EG5].

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    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Avdeeva OE,Lebedin IuS,Avdeev SN,Chuchalin AG

    更新日期:2000-01-01 00:00:00

  • [Shereshevsky-Turner syndrome: Estrogen replacement therapy and cardiovascular risk factors].

    abstract:AIM:To investigate the impact of menopausal hormone therapy (MHT) on the expression of risk factors for cardiovascular events (CVEs) in patients with Shereshevsky-Turner syndrome (STS); to elaborate an algorithm for patient management using MHT. SUBJECTS AND METHODS:From 2010 to 2012, a total of 41 patients aged 14 to...

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    pub_type: 杂志文章

    doi:10.17116/terarkh2017891048-53

    authors: Yevstigneeva OA,Andreeva EN,Grigoryan OR,Volevodz NN,Melnichenko GA,Dedov II

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  • [Cardiac changes in hereditary spinocerebellar degenerations].

    abstract::Echocardiographic alterations were compared with the clinical picture in 32 patients with different forms of hereditary spinocerebellar degenerations (HSCD). Three groups of patients were examined. Group I included patients with Friedreich's ataxia (FA), group II consisted of patients with familial cerebellar degenera...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Illarioshkin SN,Borisenko VV,Ivanova-Smolenskaia IA

    更新日期:1990-01-01 00:00:00

  • [Assessment of corrected orthogonal ECG system of McFee-Parungao leads in bicycle exercise test in patients with myocardial ischemia].

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    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Komarova OA,Kotova LA,Iarnykh EV

    更新日期:2001-01-01 00:00:00

  • [The aspects of the problem of systemic vasculitis open to discussion].

    abstract::Some controversial problems in the diagnosis of systemic vasculitis are discussed. The importance of the morphological studies is assessed. The data are provided on the interrelations between skin and systemic vasculitis, on the existence of the local forms of vasculitis, the presence of the crisscross, mixed and comb...

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    pub_type: 杂志文章,评审

    doi:

    authors: Shilkina NP

    更新日期:1989-01-01 00:00:00

  • [Endothelial vasomotor dysfunction in some forms of systemic vasculitis].

    abstract:AIM:To study vascular endothelium in patients with systemic vasculitis (SV) with non-invasive methods. MATERIAL AND METHODS:A total of 65 SV patients entered the trial: 20 patients with Henoch-Schonlein purpura (HSP), 20 patients with thromboangitis obliterans (TO), 10 patients with polyarteritis nodosa (PN), 15 patie...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Shilkina NP,Vinogradov AA

    更新日期:2007-01-01 00:00:00

  • [Diagnosis of coronary atherosclerosis using echocardiography with bicycle ergometry exercise].

    abstract:AIM:To determine sensitivity and specificity of stress echocardiography (SEC) in diagnosis of stenosing atherosclerosis of coronary arteries (CA), especially in patients recovered from Q-myocardial infarction. MATERIAL AND METHODS:The above sensitivity and specificity were studied in 75 patients (70 males and 5 female...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Dupliakov DV,Emel'ianenko VM,Svetlakova LP,Goleva SV,Sysuenkova EV

    更新日期:2004-01-01 00:00:00