Continuous monitoring of tissue pH with a fiberoptic conjunctival sensor.

Abstract:

:To assess the relationship between conjunctival pH (pHcj), arterial pH (pHa), and cardiorespiratory variables during normal and low-flow conditions, hemorrhagic hypotension was induced in eight dogs. Conjunctival pH became significantly less than control values after a hemorrhage volume of 15 mL/kg (P less than .05); mean arterial pressure (MAP) did not fall until blood loss was 20 mL/kg. There was poor correlation between pHcj and pHa, cardiac index (CI), or MAP. There was a high degree of correlation, however, between pHcj-pHa difference (delta pH) and MAP (r = -0.886), CI (r = -0.846), and tissue oxygen extraction ratio (r = .896). The results of these experiments indicate that pHcj is a sensitive monitor of peripheral tissue perfusion, and that the degree of physiologic compromise associated with hemorrhage can be determined by analysis of the difference between arterial and conjunctival pH.

journal_name

Ann Emerg Med

authors

Abraham E,Fink SE,Markle DR,Pinholster G,Tsang M

doi

10.1016/s0196-0644(85)80630-2

subject

Has Abstract

pub_date

1985-09-01 00:00:00

pages

840-4

issue

9

eissn

0196-0644

issn

1097-6760

pii

S0196-0644(85)80630-2

journal_volume

14

pub_type

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