Gynecological follow-up of parkinsonian patients on long-term bromocriptine treatment.

Abstract:

:Bromocriptine given for prolonged times at high doses has been found to induce tumors in the uterus in aged rats. To elucidate the possible tumorigenic effect of long-term treatment with bromocriptine in humans, 35 women treated with this drug for chronic parkinsonism were studied. For each patient a gynecological anamnesis and examination were performed; one or several cervicovaginal smears and endometrial samples were also taken, by jetwash. No evidence of malignant changes was seen. Thus, in this respect bromocriptine would appear to be a safe drug, even for long-term use.

authors

Grönroos M,Salmi T,Erkkola R,Liukko P,Rinne UK

doi

10.3109/00016348509154693

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

81-2

issue

1

eissn

0001-6349

issn

1600-0412

journal_volume

64

pub_type

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