Abstract:
:To our knowledge, diffuse involvement of renal parenchyma by multiple minute foci of clear cell proliferations has not been previously reported. We report such a case, found incidentally, in an 86-year-old woman who had undergone right ureteronephrectomy for pyeloureteral urothelial carcinoma. Macroscopy of the kidney showed numerous yellow dot-like cortical nodules less than 0.3 cm. Histologic examination of the kidney and nodules revealed innumerable foci of minute clear cell proliferations in a background of chronic pyelonephritis. The benign or malignant nature of those clear cell microtumors was investigated by immunohistochemistry and fluorescent in situ hybridization analysis of chromosome 3p.
journal_name
Urologyjournal_title
Urologyauthors
Pusztaszeri M,Tornillo L,Bouzourene Hdoi
10.1016/j.urology.2008.02.046subject
Has Abstractpub_date
2009-02-01 00:00:00pages
443.e9-11issue
2eissn
0090-4295issn
1527-9995pii
S0090-4295(08)00261-6journal_volume
73pub_type
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