Factors affecting initial and 6 month patency rates after intraarterial thrombolysis with high dose urokinase.

Abstract:

:Eighty-five patients who underwent 100 transcatheter intraarterial thrombolytic infusions for occlusions of suprainguinal and infrainguinal grafts and arteries were analyzed to determine the initial and 6 month results. Analysis demonstrated that suprainguinal occlusions of arteries and grafts were most likely to both lyse (89 percent) and remain patent for 6 months (86 percent). Arteries and graft occlusions had approximately the same incidence of thrombolytic recanalization (79 percent versus 74 percent). Arteries, however, had a higher incidence of 6 month patency than grafts (71 percent versus 41 percent). The inability to clear all flow-limiting lesions from the reopened portion of the vascular tree makes it highly likely that reocclusion will occur before 6 months. As a group, infrainguinal synthetic bypass grafts had the lowest patency rate at 6 months (26 percent), and suprainguinal arteries the highest rate (92 percent).

journal_name

Am J Surg

authors

McNamara TO,Bomberger RA

doi

10.1016/0002-9610(86)90454-x

subject

Has Abstract

pub_date

1986-12-01 00:00:00

pages

709-12

issue

6

eissn

0002-9610

issn

1879-1883

pii

0002-9610(86)90454-X

journal_volume

152

pub_type

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