Adjustments to the Mantel-Haenszel chi-square statistic and odds ratio variance estimator when the data are clustered.

Abstract:

:Dependence between observations on a dichotomous variable renders invalid the usual chi-square tests of independence and inflates the variances of parameter estimates. Such a situation occurs, for example, when subjects consist of members of the same family or with repeated observations on the same person. In this paper we describe methods of measuring the extent of correlation (or clustering). We also develop methods of adjusting the Mantel-Haenszel chi-square test statistic and the variance of the Mantel-Haenszel estimate of a common odds ratio in sets of 2 X 2 contingency tables.

journal_name

Stat Med

journal_title

Statistics in medicine

authors

Donald A,Donner A

doi

10.1002/sim.4780060408

subject

Has Abstract

pub_date

1987-06-01 00:00:00

pages

491-9

issue

4

eissn

0277-6715

issn

1097-0258

journal_volume

6

pub_type

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