Abstract:
:The present report evaluates a method for the determination of the maximal velocity of the outward sodium, potassium, chlorine (Na-K-Cl) cotransport in erythrocytes. The loading procedure was carried out using the ionophore nystatin. The technical error for this assay, based on concurrent analysis of randomized blind duplicate samples, was 8.04% of the sample mean and 27.5% of the sample standard deviation. The assay was stable over time and reproducible. Fasting was not necessary. The ratio of intra- to interindividual variances was small. The cells can be safely preserved in an appropriate preservation solution without modification of the ion transport assay. The assay appears to be adequate for use in large-scale field trials.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Trevisan M,Canessa M,Laurenzi M,Di Muro MR,De Colle S,Franzese A,Iacone R,De Chiara Fdoi
10.1093/oxfordjournals.aje.a114602subject
Has Abstractpub_date
1987-05-01 00:00:00pages
860-8issue
5eissn
0002-9262issn
1476-6256journal_volume
125pub_type
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