Abstract:
:Positron emission tomography (PET) and combined PET/CT provide powerful metabolic and anatomical information together in a single exam. This article reviews the fundamentals of PET physics, the state of the art and future directions in PET technology, and the current clinical applications of PET. The latter is quite diverse and includes oncology, cardiology, neurology, and infection and inflammation imaging, all with FDG as the tracer. Additionally, novel radiopharmeuticals are under development, many of which are target cellular processes that are more specific than glucose metabolism.
journal_name
Radiol Clin North Amjournal_title
Radiologic clinics of North Americaauthors
Mittra E,Quon Adoi
10.1016/j.rcl.2008.10.005subject
Has Abstractpub_date
2009-01-01 00:00:00pages
147-60issue
1eissn
0033-8389issn
1557-8275pii
S0033-8389(08)00187-5journal_volume
47pub_type
杂志文章,评审abstract::Since its inception, CT scan has had a dominant role in hepatic imaging. Recent advances including helical CT scan and bolus-triggered scan initiation software packages have had a significant impact. Issues regarding volume, rate of administration, and type of intravenous contrast are being distilled. Workstations for...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0033-8389(05)70020-8
更新日期:1998-03-01 00:00:00
abstract::Acute abdominal pain in pregnancy presents diagnostic and therapeutic challenges. Ultrasound remains the primary imaging investigation of the pregnant abdomen because of its availability, portability, and lack of ionizing radiation. MR imaging has been shown to be useful in the diagnosis of gynecologic and obstetric p...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.rcl.2015.06.013
更新日期:2015-11-01 00:00:00
abstract::This article serves as a practical reference to optimize the performance of computed tomography colonography in the detection of colorectal neoplasia. A specific protocol in use at 2 US university programs as well as defined interpretation strategies will be described. With this framework in place, various clinical pe...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.rcl.2018.05.004
更新日期:2018-09-01 00:00:00
abstract::Many changes have occurred in the past decade in the imaging of the breast. These improvements have led to more sensitive and specific breast imaging and to the widespread use of minimally invasive biopsy techniques. They have also facilitated a closer working relationship between breast imager and surgeon and have co...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0033-8389(01)00006-9
更新日期:2002-05-01 00:00:00
abstract::Magnetic resonance (MR) enterography is a targeted examination of the gastrointestinal tract, particularly the small intestine, without nasojejunal intubation (in which case it is referred to as MR enteroclysis). Until recently, MR imaging of the small bowel could not reliably compete with the high-quality small bowel...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.rcl.2012.09.007
更新日期:2013-01-01 00:00:00
abstract::Magnetic resonance (MR) has noninvasively imaged the proximal coronary arteries, areas of infarction, and a variety of congenital heart lesions. Further technical improvement may extend cardiac MR from the realm of research to clinical utility. ...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1984-12-01 00:00:00
abstract::Supply-line deprivation is a major source of developmental fetal pathology. Clinical surveys have tended to emphasize the role of placental failure, although the umbilical cord may also be a site of injury. Supply-line limitations are met by a series of active fetal compensatory maneuvers. These include growth retarda...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Osteoporosis, a condition of decreased bone tissue that increases the likelihood of fracture, places a significant burden on our society in terms of health cost and morbidity. The most common type of osteoporosis is involutional, and two subtypes are recognized: type 1 and type 2. Type 1, or postmenopausal, osteoporos...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1991-01-01 00:00:00
abstract::Given the high prevalence, increasing incidence, and significant morbidity and mortality related to hepatocellular carcinoma (HCC), a robust and cost-effective screening and surveillance program is needed. Most societies recommend ultrasound for HCC screening, despite lack of standardization in imaging acquisition, re...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.rcl.2017.06.012
更新日期:2017-11-01 00:00:00
abstract::The use of RT in pediatric cancer has been virtually eliminated in certain diseases (NHL); greatly reduced in some (Wilms' tumor, ALL, neuroblastoma); and refined and modified in others (rhabdomyosarcoma, Ewing's sarcoma). At present, however, it seems clear that RT will continue to be an important modality (particula...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1997-11-01 00:00:00
abstract::Neonatal cranial ultrasound continues to be a popular initial imaging modality because of the safety, low-cost, and portability of the examination. The higher frequency transducers and enhanced ability for signal processing that is possible with current ultrasound machines improves visualization of complex congenital ...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0033-8389(05)70253-0
更新日期:1999-11-01 00:00:00
abstract::MR and CT are complementary studies in evaluating inflammatory disease or neoplasms of the mastoid and middle ear cavities. CT should be performed prior to MR in the evaluation of patients with primary temporal bone pathology because of its ability to detect and delineate both soft tissue and bony abnormalities. CT sh...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1989-03-01 00:00:00
abstract::The term "pseuduotumor" is currently used to mean idiopathic orbital inflammation. CT can be of help in differentiating idiopathic orbital inflammation from thyroid ophthalmopathy and lymphoid tumors. The CT findings are reviewed along with important clinical and pathologic aspects. ...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract::An overview of the pathology of extranodal lymphoma is presented. The emphasis of this presentation is on the classification system of extranodal lymphomas, including both B-cell and T-cell lymphomas, based on their morphology, phenotype, and molecular alterations. ...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.rcl.2016.03.001
更新日期:2016-07-01 00:00:00
abstract::One of the major strengths of F-18 fluorodeoxyglucose-positron emission tomography (FDG-PET) in breast cancer imaging is in the evaluation of patients who have suspected loco-regional recurrence or distant metastasis. In general, FDG-PET is more sensitive than conventional imaging for the detection of recurrent diseas...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.rcl.2007.05.005
更新日期:2007-07-01 00:00:00
abstract::Spinal stenosis in either the cervical or lumbar spinal segments is one of the most common indications for spine imaging and intervention, particularly among the elderly. This article examines the pathophysiology and imaging of the corresponding clinical syndromes, cervical spondylotic myelopathy or neurogenic intermi...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.rcl.2012.04.007
更新日期:2012-07-01 00:00:00
abstract::Acute pelvic pain in the nonpregnant woman is one of the most common conditions requiring emergent medical evaluation in routine clinical practice. Although clinical evaluation and laboratory testing are essential, imaging plays a central role. Although various adnexal and uterine disorders may result in acute pelvic ...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.rcl.2019.11.002
更新日期:2020-03-01 00:00:00
abstract::Fine-needle aspiration (FNA) and core biopsy of masses in the neck predominantly include samples from thyroid nodules, parathyroids and lymph nodes. The diagnostic rate of a thyroid nodule FNA improves up to 6 passes and then does not significantly change. Thyroid FNA can be performed on patients who are anticoagulate...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.rcl.2020.07.005
更新日期:2020-11-01 00:00:00
abstract::The American College of Radiology Breast Imaging and Reporting Data System (ACR BI-RADS) defines a mass as a space-occupying lesion seen in at least two projections. This article focuses on the management of breast masses with mammography and ultrasonography. Recommended work-up pathways are modified for nonpalpable m...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0033-8389(05)70193-7
更新日期:2000-07-01 00:00:00
abstract::Imaging has a key role in the identification of bronchiectasis. Over the years, imaging tests have become increasingly accurate in depicting the features of early bronchiectasis. This article covers the clinical, pathologic, and functional features of bronchiectasis; high-resolution CT scan technique; the signs of bro...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0033-8389(05)70009-9
更新日期:1998-01-01 00:00:00
abstract::Lower resolution CT scanners play an important role in the evaluation of the cerebellopontine angle, but careful integration along with the older conventional examinations is often necessary. A high-resolution CT scanner may provide all the necessary information. With proper techniques, bony changes are most clearly a...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1982-03-01 00:00:00
abstract::In this article, the numerous proven applications of diagnostic ultrasound to the assessment of disease processes affecting the popliteal fossa and lower extremities have been discussed. Popliteal cysts and aneurysms, hematomas, cellulitis, abscesses, soft tissue neoplasms, and other space-occupying fluid collections ...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1988-01-01 00:00:00
abstract::Magnetic resonance imaging provides superb anatomic detail and greater sensitivity to the detection of most lesions than any other imaging modality. The topics covered in this article include the physical principles of MR imaging and imaging of normal renal anatomy and pathologic renal entities, including pathologic c...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1984-06-01 00:00:00
abstract::High-quality aortic imaging plays a central role in the management of patients with thoracic aortic aneurysm. Computed tomography angiography and magnetic resonance angiography are the most commonly used techniques for thoracic aortic aneurysm diagnosis and imaging surveillance, with each having unique strengths and l...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.rcl.2020.02.009
更新日期:2020-07-01 00:00:00
abstract::Imaging plays an important role in the diagnosis and management of sports injuries of childhood and adolescence. The injuries discussed are typical of those seen in the skeletally immature athlete. Imaging specialists must be able to apply the full range of imaging modalities when evaluating the injured young athlete....
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0033-8389(05)70310-9
更新日期:2001-07-01 00:00:00
abstract::Congenital nonvascular anomalies of the lung can be subdivided into those affecting the bronchial tree and those affecting parenchymal abnormalities. Embryologic development of the lung is briefly reviewed to facilitate an understanding of developmental pulmonary anomalies. Clinical, radiographic, and therapeutic aspe...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1991-03-01 00:00:00
abstract::MR imaging has become the definitive diagnostic procedure for the evaluation of suspected spinal dysrhaphic processes. Techniques for spinal MR imaging are discussed and MR findings in patients with surgically verified dysrhaphic spinal lesions are reviewed. ...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1988-03-01 00:00:00
abstract::The treatment strategy in advanced non-small cell lung cancer (NSCLC) has evolved from empirical chemotherapy to a personalized approach based on histology and molecular markers of primary tumors. Targeted therapies are directed at the products of oncogenic driver mutations. Immunotherapy facilitates the recognition o...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.rcl.2018.01.012
更新日期:2018-05-01 00:00:00
abstract::Swallowing requires the coordinated action of the alimentary tract from the oral cavity to the gastroesophageal junction. Any structural or functional abnormality along this pathway will interfere with swallowing. The "barium swallow" or pharyngoesophagogram requires examination of the oral cavity, pharynx, esophagus,...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1993-11-01 00:00:00
abstract::CT currently plays a vital role in pancreatic cancer staging. Continued advancements in computers, scanner technology, and 3D software have improved CT detection of smaller masses and staging. In particular, the introduction of MDCT and real-time 3D volume-rendering software have greatly improved the visualization of ...
journal_title:Radiologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0033-8389(02)00041-6
更新日期:2002-12-01 00:00:00