Sensitivity to change and predictive validity of the MOODS-SR questionnaire, last-month version.


BACKGROUND:Instruments that are intended to measure change over time need to emphasize sensitivity to change as a central property. The aims of this report are to test whether the MOODS-SR, a measure of mood spectrum symptomatology, is sensitive to changes during acute and continuation treatment of depression and whether residual mood spectrum symptoms predict relapse in the subsequent 6 months. METHODS:The study sample includes 316 patients with nonpsychotic depression participating in the protocol 'Depression: the search for treatment-relevant phenotypes'. Patients were initially randomized to selective serotonin reuptake inhibitors or interpersonal psychotherapy and then treated for 9 months using an algorithm-based protocol. Measures of mood symptomatology included the self-report version of the structured clinical interview for mood spectrum (MOODS-SR), the Quick Inventory for Depressive Symptomatology and the Hamilton Rating Scale for Depression. RESULTS:Repeated-measures ANOVA indicates that during the acute phase MOODS scores decrease significantly from baseline to weeks 6 and 12. This decrease was significantly different (p < 0.001) between those who remitted and those who did not remit on the depressive, the rhythmicity component and the total score. Nonrelapsing subjects had stable scores across the continuation phase, while among relapsing subjects, a significant increase was found in the depressive component (p < 0.001), the rhythmicity component (p = 0.024) and the total score (p < 0.001), at 2 months, followed by a decrease from 2 to 6 months. Scores on the depressive component at the entry into continuation predicted relapse in the subsequent 6 months. CONCLUSIONS:Our findings suggest that the MOODS-SR is sensitive to change in depression status and may help the clinician to detect symptoms and signs not considered by established symptom severity scales.


Psychother Psychosom


Miniati M,Rucci P,Frank E,Oppo A,Kupfer DJ,Fagiolini A,Cassano GB




Has Abstract


2009-01-01 00:00:00














  • Feasibility of exercise training for the short-term treatment of generalized anxiety disorder: a randomized controlled trial.

    abstract:BACKGROUND:Exercise training may be especially helpful for patients with generalized anxiety disorder (GAD). We conducted a randomized controlled trial to quantify the effects of 6 weeks of resistance (RET) or aerobic exercise training (AET) on remission and worry symptoms among sedentary patients with GAD. METHODS:Th...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,随机对照试验


    authors: Herring MP,Jacob ML,Suveg C,Dishman RK,O'Connor PJ

    更新日期:2012-01-01 00:00:00

  • Psychoneuroendocrinology of stress and emotions: issues for future research.

    abstract::It is stated that much psychoneuroendocrinological research is carried out that lacks a theoretical framework and therefore adds little to our current knowledge. Therefore, five research issues have been presented which need further exploration: (1) the temporal relation between subjective and biological stress respon...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,评审


    authors: Vingerhoets AJ,Assies J

    更新日期:1991-01-01 00:00:00

  • The influence of social factors on the response to stress.

    abstract::The studies described in this paper provide evidence for the importance of social factors in determining the response of the hypothalamic-pituitary-adrenal (H-P-A) system to stress. The presence of familiar social partners can reduce or eliminate the cortisol response to either loss of a significant social relationshi...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Levine S

    更新日期:1993-01-01 00:00:00

  • Psychological prodromata of myocardial infarction and sudden death.

    abstract::In this prospective study a psychological test (the "Maastricht Questionnaire') was constructed which measures feelings of vital exhaustion and depression. It is shown that those subjects who have elevated scores on this test have more chance to get a new coronary event within a period of 10 months than those who have...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Appels A

    更新日期:1980-01-01 00:00:00

  • Life events and alopecia areata.

    abstract::48 patients with alopecia areata, 30 with common baldness, 30 with fungal infections underwent the Paykel's Interview for recent life events. In the 6 months preceding onset, alopecic patients reported 123 events (mean = 2.56), patients with common baldness 22 events (mean = 0.73), patients with fungal infections 15 (...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Perini GI,Veller Fornasa C,Cipriani R,Bettin A,Zecchino F,Peserico A

    更新日期:1984-01-01 00:00:00

  • Financial ties between DSM-IV panel members and the pharmaceutical industry.

    abstract:BACKGROUND:Increasing attention has been given to the transparency of potential conflicts of interest in clinical medicine and biomedical sciences, particularly in journal publishing and science advisory panels. The authors examined the degree and type of financial ties to the pharmaceutical industry of panel members r...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Cosgrove L,Krimsky S,Vijayaraghavan M,Schneider L

    更新日期:2006-01-01 00:00:00

  • Psychotherapy of childhood anxiety disorders: A meta-analysis.

    abstract:BACKGROUND:The present study compared the efficacy of psychotherapy for childhood anxiety disorders (excluding trials solely treating post-traumatic stress disorder or obsessive-compulsive disorder). METHODS:The meta-analysis included studies that met the basic CONSORT (consolidated standards of reporting trials) crit...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,meta分析


    authors: In-Albon T,Schneider S

    更新日期:2007-01-01 00:00:00

  • Integrating cognitive therapy and pharmacotherapy in the treatment and prophylaxis of depression: a novel approach.

    abstract::Psychiatric clinicians frequently prescribe biologic treatments such as antidepressant medication in combination with psychologic treatments such as psychotherapy. In the present article we propose a model integrating antidepressant treatment with Beck's cognitive therapy, a form of psychotherapy with established effi...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,评审


    authors: Pava JA,Fava M,Levenson JA

    更新日期:1994-01-01 00:00:00

  • Psychophysiological responses of borderline hypertensives in two experimental situations.

    abstract::Given the contradictory reports concerning psychophysiological reactivity of hypertensives this issue was reexamined. In contrast to the large majority of studies, the hypertensive sample should not be made up of patients in medical care and the control group should be comparable in all relevant aspects other than blo...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Köhler T,Scherbaum N,Ritz T

    更新日期:1995-01-01 00:00:00

  • Inverse and direct cancer comorbidity in people with central nervous system disorders: a meta-analysis of cancer incidence in 577,013 participants of 50 observational studies.

    abstract:BACKGROUND:There is a lack of scientific consensus about cancer comorbidity in people with central nervous system (CNS) disorders. This study assesses the co-occurrence of cancers in patients with CNS disorders, including Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), autism spectrum disorders, Down's s...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,meta分析


    authors: Catalá-López F,Suárez-Pinilla M,Suárez-Pinilla P,Valderas JM,Gómez-Beneyto M,Martinez S,Balanzá-Martínez V,Climent J,Valencia A,McGrath J,Crespo-Facorro B,Sanchez-Moreno J,Vieta E,Tabarés-Seisdedos R

    更新日期:2014-01-01 00:00:00

  • Cognitive-behavioural therapy for bulimia nervosa and binge eating disorder. A review.

    abstract::Cognitive-behavioural therapy (CBT) programmes for bulimia nervosa (BN) have been considerably refined during the last 2 decades, and such a treatment is now extensively used. The present paper describes the treatment rationale and structure, and reviews the available evidence on its efficacy. Compared to any other ps...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,评审


    authors: Ricca V,Mannucci E,Zucchi T,Rotella CM,Faravelli C

    更新日期:2000-11-01 00:00:00

  • Anxiety and hope during the course of three different medical illnesses: a longitudinal study.

    abstract:BACKGROUND:Somatic illness and its consequences evoke strong emotions of various kinds. They may affect the course of illness and the treatment results through their physiological components. The purpose of the study was to explore emotional reactions to different kinds of illnesses and changes of these emotions over t...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Heszen-Niejodek I,Gottschalk LA,Januszek M

    更新日期:1999-01-01 00:00:00

  • A study of somatopsychic vulnerability in encopretic children.

    abstract::In this article the results of a study to determine the degree of somatopsychic vulnerability in children with encopresis are discussed. A checklist was constructed for the registration of somatic and functional data relevant to encopresis. Twenty-five children with encopresis were compared with a control group. The e...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Wolters WH,Wauters EA

    更新日期:1975-01-01 00:00:00

  • Psychotherapeutic management of suicide attempts in children and early adolescents: working with parents.

    abstract::Metatherapy (a psychotherapeutic procedure based upon parental couple collaboration) is a technique useful for working with severely disorganized family contexts, in which psychopathological diseases (such as psychotic or psychosomatic disorders, suicide attempts of the children etc.) can appear. The management of the...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Vaz-Leal FJ

    更新日期:1989-01-01 00:00:00

  • The Clinical Inadequacy of the Placebo Model and the Development of an Alternative Conceptual Framework.

    abstract::Placebo effects are often attributed to clinical interactions and contextual factors that affect expectations of the patient about the treatment and result in symptom changes. The prevailing conceptualization consists of an undifferentiated placebo response that needs to be minimized in controlled investigations and m...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Fava GA,Guidi J,Rafanelli C,Rickels K

    更新日期:2017-01-01 00:00:00

  • Cognitive Behavior Therapy May Sustain Antidepressant Effects of Intravenous Ketamine in Treatment-Resistant Depression.

    abstract:INTRODUCTION:Ketamine has shown rapid though short-lived antidepressant effects. The possibility of concerning neurobiological changes following repeated exposure to the drug motivates the development of strategies that obviate or minimize the need for longer-term treatment with ketamine. In this open-label trial, we i...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,多中心研究


    authors: Wilkinson ST,Wright D,Fasula MK,Fenton L,Griepp M,Ostroff RB,Sanacora G

    更新日期:2017-01-01 00:00:00

  • Circadian blood pressure patterns and life stress.

    abstract:BACKGROUND:Scarce data are available on the influence of psychological aspects on 24-hour ambulatory blood pressure patterns either in normotensive or hypertensive subjects. This study was designed to evaluate the relationship between psychological profile and changes in daytime/nighttime blood pressure rhythm. METHOD...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Fallo F,Barzon L,Rabbia F,Navarrini C,Conterno A,Veglio F,Cazzaro M,Fava GA,Sonino N

    更新日期:2002-11-01 00:00:00

  • Randomized controlled comparison of two cognitive behavioral therapies for obese children: mother versus mother-child cognitive behavioral therapy.

    abstract:BACKGROUND:Parent-child treatments have been shown to be superior to child-focused treatments of childhood obesity. Yet until now, the comparative effectiveness of parent-only and parent-child approaches has been little studied. METHOD:Fifty-six obese children and their families were randomly assigned to a 16-session ...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,随机对照试验


    authors: Munsch S,Roth B,Michael T,Meyer AH,Biedert E,Roth S,Speck V,Zumsteg U,Isler E,Margraf J

    更新日期:2008-01-01 00:00:00

  • Illness behavior, emotional stress and psychosocial factors among asymptomatic HIV-infected patients.

    abstract:BACKGROUND:Over the last years the way in which patients with chronic physical illness respond to their illness (illness behavior) has been explored by several studies. This study sought to examine characteristics of illness behavior and to investigate the association between illness behavior and psychosocial and clini...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 临床试验,杂志文章


    authors: Grassi L,Righi R,Makoui S,Sighinolfi L,Ferri S,Ghinelli F

    更新日期:1999-01-01 00:00:00

  • Psychoanalytic-Interactional Therapy versus Psychodynamic Therapy by Experts for Personality Disorders: A Randomized Controlled Efficacy-Effectiveness Study in Cluster B Personality Disorders.

    abstract:BACKGROUND:With regard to cluster B personality disorders, most psychotherapeutic treatments focus on borderline personality disorder. Evidence-based treatments for patients with other cluster B personality disorders are not yet available. Psychoanalytic-interactional therapy (PIT) represents a transdiagnostic treatmen...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,随机对照试验


    authors: Leichsenring F,Masuhr O,Jaeger U,Rabung S,Dally A,Dümpelmann M,Fricke-Neef C,Steinert C,Streeck U

    更新日期:2016-01-01 00:00:00

  • The role of anger in adherence to highly active antiretroviral treatment in patients infected with HIV.

    abstract:BACKGROUND:Adherence to highly active antiretroviral treatment (HAART) is critical to long-term treatment success in patients infected with human immunodeficiency virus (HIV). However, the relationship between psychological variables and medication adherence is still poorly understood. The aim of this study was to inve...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Leombruni P,Fassino S,Lavagnino L,Orofino G,Morosini P,Picardi A

    更新日期:2009-01-01 00:00:00

  • Alexithymia and psychopathology in patients with psychiatric and functional gastrointestinal disorders.

    abstract:BACKGROUND:Alexithymia and psychopathology may influence the way individuals experience psychological distress and somatic symptoms. This study evaluated patients referred to psychiatric and gastroenterologic outpatient settings in order to investigate the levels of alexithymia and psychopathology, and the possible rol...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Porcelli P,Affatati V,Bellomo A,De Carne M,Todarello O,Taylor GJ

    更新日期:2004-03-01 00:00:00

  • Personality traits and metabolic control: a study in insulin-dependent diabetes mellitus patients.

    abstract:BACKGROUND:In the present study the authors evaluated the relationship between personality traits (according to DSM-III-R) and poor metabolic control in an adult onset insulin-dependent diabetes mellitus sample (n = 77). METHODS:Personality traits were assessed with the Personality Diagnostic Questionnaire--Revised. M...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Orlandini A,Pastore MR,Fossati A,Clerici S,Sergi A,Balini A,Maffei C,Secchi A,Pozza G

    更新日期:1997-01-01 00:00:00

  • Studies of endocrine and affective functions in complex flight manoeuvres.

    abstract::Endocrine and metabolic changes, as well as affective functions, were studied in eight healthy volunteers anticipating and executing a prearranged sequence of aerobatic flight. Control measurements were made at complete physical and mental rest. The following were determined: anxiety and hostility levels, blood glucos...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Pinter EJ,Peterfy G,Cleghorn JM

    更新日期:1975-01-01 00:00:00

  • Language acquisition in relation to cumulative posttraumatic stress disorder symptom load over time in a sample of re-settled refugees.

    abstract:OBJECTIVE:To study the effects of symptoms of posttraumatic stress disorder (PTSD), depression and dissociation as well as cumulative symptom load on language learning during the introduction phase in re-settled refugees. METHOD:Participants were re-settled refugees of Iraqi origin. They were assessed by means of a st...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Söndergaard HP,Theorell T

    更新日期:2004-09-01 00:00:00

  • Do somatic complaints predict subsequent symptoms of depression?

    abstract:BACKGROUND:Evidence suggests substantial comorbidity between symptoms of somatization and depression in clinical as well as nonclinical populations. However, as most existing research has been retrospective or cross-sectional in design, very little is known about the specific nature of this relationship. In particular,...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Terre L,Poston WS,Foreyt J,St Jeor ST

    更新日期:2003-09-01 00:00:00

  • Alexithymia and psychological distress among frequent attendance patients in health care.

    abstract:BACKGROUND:The aim of the present study was to find out whether alexithymia is common in frequently attending primary health care patients and whether alexithymia and psychological distress are associated in these patients. METHODS:Alexithymia was measured by the TAS-26 and psychological distress by the SCL-25 in a ra...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Joukamaa M,Karlsson H,Sholman B,Lehtinen V

    更新日期:1996-01-01 00:00:00

  • Suitability of bupropion SR for nicotine-dependent smokers: problems in a practice setting.

    abstract:BACKGROUND:Bupropion SR (Zyban) has been shown in randomized controlled trials to be an efficacious pharmacological aid for smoking cessation; however, recent reports have raised serious concerns about the breadth of its applicability without complications or contraindications. METHODS:We examined this issue in a well...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Kohlenberg BS,Antonuccio DO,Hayes SC,Gifford EV,Piasecki MP

    更新日期:2004-07-01 00:00:00

  • Coping with fear of long-term complications in diabetes mellitus: a model clinical program.

    abstract::Preliminary results are reported on the efficacy of a behaviorally oriented group therapy (n = 17) intended to improve coping with fear of long-term complications in patients with diabetes mellitus. Treatment consisted of exposure in imagination, relaxation training and analysis of dysfunctional health beliefs. Pre-, ...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章


    authors: Zettler A,Duran G,Waadt S,Herschbach P,Strian F

    更新日期:1995-01-01 00:00:00

  • Internet-based psychodynamic versus cognitive behavioral guided self-help for generalized anxiety disorder: a randomized controlled trial.

    abstract:BACKGROUND:Guided Internet-based cognitive behavior therapy (ICBT) has been tested in many trials and found to be effective in the treatment of anxiety and mood disorders. Generalized anxiety disorder (GAD) has also been treated with ICBT, but there are no controlled trials on guided Internet-based psychodynamic treatm...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,随机对照试验


    authors: Andersson G,Paxling B,Roch-Norlund P,Östman G,Norgren A,Almlöv J,Georén L,Breitholtz E,Dahlin M,Cuijpers P,Carlbring P,Silverberg F

    更新日期:2012-01-01 00:00:00