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Clostridium septicum aortitis: Report of two cases and review of the literature.

Abstract：

:Clostridium septicum aortitis is a rare infection that has a strong association with occult colonic malignancy. To our knowledge, we report the 25th and 26th cases of C septicum aortitis in the English literature and make recommendations for its management. The first patient was a 75-year-old man who presented with abdominal pain. Computed tomography showed the presence of periaortic gas. He underwent aortic débridement and extra-anatomic bypass after blood cultures revealed C septicum. Four months after the initial presentation, he was readmitted with lethargy, found to have recurrent periaortic gas, and died. The second patient was a 76-year-old woman who presented with a 5-cm abdominal aortic aneurysm with surrounding retroperitoneal gas. She underwent emergency aortic ligation and retroperitoneal débridement. Her blood and intraoperative tissue cultures also grew C septicum. She had a prolonged postoperative course and ultimately died on hospital day 94. Both patients were found to have concurrent colon adenocarcinomas. C septicum aortitis is a lethal disease that necessitates prompt surgical intervention and appropriate antibiotic therapy. The strong association of C septicum with occult malignancy should prompt the astute clinician to undertake an exhaustive search for a neoplastic process.

journal_name

J Vasc Surg

journal_title

Journal of vascular surgery

authors

Seder CW,Kramer M,Long G,Uzieblo MR,Shanley CJ,Bove P

doi

10.1016/j.jvs.2008.11.058

subject

Has Abstract

pub_date

2009-05-01 00:00:00

pages

1304-9

issue

5

eissn

0741-5214

issn

1097-6809

pii

S0741-5214(08)01992-7

journal_volume

49

pub_type

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