Abstract：
BACKGROUND/OBJECTIVES:To conduct a comparative study of retinal nerve fibre layer (RNFL) thickness and choroidal thickness of psoriasis patients and healthy volunteers. METHODS:This study included 35 severe psoriasis patients, 35 mild psoriasis patients and 35 healthy individuals. RNFL and choroidal thickness analysis were performed by spectral field optical coherence tomography (SD-OCT). Only patients with psoriasis vulgaris who have not used systemic therapy for the last 3 months were included in the study. RESULTS:In the severe psoriasis group, the RSLT thickness was found to be statistically significantly thinner and the choroid thickness was thicker than the mild psoriasis and control group (P < .001). There was no significant difference in terms of RNLF and choroid thickness compared to mild psoriasis and the control group (P > .05). The correlation between length of the disease duration, RNFL and choroidal thickness was not significant (P > 0,05). CONCLUSION:The increase in choroidal thickness was found to be significant, while with respect to RNFL thickness, a decrease was evident, a possible indicator of damage to microvascular structures in the choroid and ganglion cells, especially in patients with severe psoriasis. Therefore, choroidal and RSLT thickness measurement with OCT device can assist in the detection of damage to psoriasis.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Aksoy M,Toptan M,An Idoi
10.1111/ijcp.13904subject
Has Abstractpub_date
2020-12-08 00:00:00pages
e13904eissn
1368-5031issn
1742-1241pub_type
杂志文章abstract：AIMS:The IMPROVE observational study evaluated the safety profile and effectiveness of biphasic insulin aspart 30/70 (BIAsp 30) in patients with type 2 diabetes in routine practice in 11 countries. METHODS:Patients who initiated insulin therapy with, or switched existing insulin therapy to, BIAsp 30 in routine care we...
journal_title：International journal of clinical practice
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1111/j.1742-1241.2009.02002.x
更新日期：2009-03-01 00:00:00
abstract：:Gastrointestinal tract (GIT) foreign bodies represent a significant clinical problem in the Emergency Department, causing a high degree of financial burden, morbidity and mortality. A large variety of foreign bodies are accidentally ingested or inserted into the GIT in different age groups. This a retrospective review...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1368-5031.2006.00709.x
更新日期：2006-06-01 00:00:00
abstract：AIMS:The aim of this study was to assess patient characteristics, medication treatment patterns and healthcare resource utilization among men with existing erectile dysfunction (ED) or benign prostatic hyperplasia (BPH), who are newly diagnosed with the second condition (BPH or ED) compared with those with only one con...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.12657
更新日期：2015-08-01 00:00:00
abstract：:Age-related macular degeneration (AMD) is the leading cause of adult blindness among individuals aged 50 and older in the Western world, with the neovascular form of AMD responsible for the most severe and rapid visual loss. Although monotherapy with currently available treatments can slow the rate of loss of vision i...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2007.01299.x
更新日期：2007-03-01 00:00:00
abstract：AIM:To raise awareness on nocturia disease burden and to provide simplified aetiologic evaluation and related treatment pathways. METHODS:A multidisciplinary group of nocturia experts developed practical advice and recommendations based on the best available evidence supplemented by their own experiences. RESULTS:Noc...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/ijcp.13027
更新日期：2017-11-01 00:00:00
abstract：:It is difficult to make a diagnosis when malignancy presents as fever of unknown origin (FUO). In order to update information on this disease entity, we performed a retrospective survey on adult cancer patients (n=48) presenting with FUO who were admitted to our university hospital between 1989 and 2002. All 48 patien...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2003-07-01 00:00:00
abstract：:The role of low-density lipoprotein in the development of coronary heart disease (CHD) is well recognised. There is also growing evidence that high-density lipoprotein cholesterol (HDL-C) is a powerful inverse predictor for premature CHD and that maintaining a high HDL-C level may guard against atherosclerosis. Patien...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：2002-12-01 00:00:00
abstract：AIMS:Although many elderly individuals suffer from type 2 diabetes, the effectiveness of cardioprotective drugs in primary prevention of cardiovascular events in clinical practice in this population has rarely been evaluated. We aimed to assess the effectiveness of, (i) angiotensin converting enzyme inhibitors or angio...
journal_title：International journal of clinical practice
pub_type： 杂志文章,多中心研究
doi：10.1111/ijcp.12503
更新日期：2015-03-01 00:00:00
abstract：AIMS:This review aims at analysing the published literature on chemotherapy for hormone-refractory prostate cancer (HRPC) to provide recommendations for the treatment of this important patient group. METHODS:The information for this review was compiled using the PubMed and Medline databases and the Proceedings of the ...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2007.01551.x
更新日期：2007-12-01 00:00:00
abstract：:A 43-year-old female patient with Basedow-Graves' disease developed agranulocytosis in the eighth month of propylthiouracil therapy. After discontinuing the drug, a broad spectrum antibiotic regimen plus recombinant human granulocyte colony-stimulating factor (G-CSF), a human haematopoietic growth factor, were started...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1999-07-01 00:00:00
abstract：OBJECTIVE:The impacts of renin-angiotensin system (RAS)-targeting antihypertensive drugs on Alzheimer's disease (AD) remain controversial. We performed this meta-analysis to evaluate the precise value of RAS-targeting antihypertensive drugs in terms of attenuating incidence of AD and slowing down cognitive decline in p...
journal_title：International journal of clinical practice
pub_type： 杂志文章,meta分析
doi：10.1111/ijcp.12626
更新日期：2015-06-01 00:00:00
abstract：:Both the incidence of twin pregnancy and the demand for prenatal diagnosis are increasing. Unfortunately, biochemical screening and ultrasound scanning are less reliable for prenatal diagnosis in twin pregnancies than in singletons. Amniocentesis and chorionic villous biopsy are usually diagnostic in singleton pregnan...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：1997-07-01 00:00:00
abstract：:We report an unusual presentation of non-Hodgkin's lymphoma of the thyroid which mimicked an acute infective thyroiditis and was associated with acute stridor and dysphagia. The mode of presentation and diagnosis of thyroid lymphoma are discussed and the value of early fine needle aspiration emphasised. ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1998-11-01 00:00:00
abstract：PURPOSE:Whilst core curricula in neurology are nationally standardised, in real-world clinical practice, different approaches may be taken by individual consultants. The aims of this study were to investigate differences by assessing: (a) variance in diagnostic and investigative practice, using a case-based analysis of...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13830
更新日期：2020-11-12 00:00:00
abstract：:The aim of thromboprophylaxis is to minimise the incidence of clinically relevant venous thromboembolism (VTE) but in many trials designed to determine the efficacy of thromboprophylactic agents, asymptomatic VTE is included in the primary endpoint. Since asymptomatic events occur much more frequently than symptomatic...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：
更新日期：2003-05-01 00:00:00
abstract：AIM:To develop a management strategy (rehabilitation programme) for erectile dysfunction (ED) after radiotherapy (RT) or androgen deprivation therapy (ADT) for prostate cancer that is suitable for use in a UK NHS healthcare context. METHODS:PubMed literature searches of ED management in this patient group together wit...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.12512
更新日期：2015-01-01 00:00:00
abstract：INTRODUCTION:Peripheral arterial disease (PAD) is an underdiagnosed prevalent disease which implies high cardiovascular risk. Professionals usually depend on physical examination to screen for PAD. OBJECTIVE:To assess the diagnostic accuracy of physical examination to screen for PAD in a rural Primary Care population ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13253
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:Alternatives to acute hospital admission are required to accommodate the increasing pressures on health services. Since physiotherapists and occupational therapists are integral to inpatient teams, they may also be integral to admission replacement services, and thus their roles in these services merit inves...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13462
更新日期：2020-06-01 00:00:00
abstract：:Fever of unknown origin (FUO) is defined as the body temperature higher than 38.3 degrees C on several occasions and lasting longer than 3 weeks, with the aetiology remaining uncertain after 1 week of investigation. In this study, we reviewed 57 patients with FUO hospitalised in our inpatient department between 1998 a...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1368-5031.2005.00471.x
更新日期：2005-08-01 00:00:00
abstract：:Marijuana is the most commonly used illicit drug while its abuse and dependence has an increasing prevalence among the young population. Marijuana smoking affects the circulatory system triggering various cardiovascular events. Of note, recent case reports indicate a possible association with atrial fibrillation (AF)....
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2007.01505.x
更新日期：2008-02-01 00:00:00
abstract：OBJECTIVE:To assess secondary prevention of fragility fractures by orthopaedic surgeons in the UK and study the effect of multidisciplinary approach in providing secondary prevention. METHODS:A survey was conducted consisting of a postal questionnaire sent to 1000 UK orthopaedic surgeons. 750 valid responses were rece...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1742-1241.2007.01662.x
更新日期：2008-03-01 00:00:00
abstract：:Tuberculosis is an uncommon cause of carpal tunnel syndrome. We report a patient with systemic lupus erythematosus who developed hand numbness. Ultrasonic, operative and microbiological findings supported the diagnosis of median nerve compression secondary to a tuberculous abscess. The symptoms resolved with surgical ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:We reviewed the results of 22 operations performed on 21 patients for the relief of de Quervain's disease over the last six years. At a mean follow-up of 34 months (range 4-78 months), 18 of 22 wrists had complete relief of their original symptoms. One patient required reoperation because of inadequate decompression, ...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND:'Do Not Attempt Cardiopulmonary Resuscitation' (DNACPR) orders are made frequently for older people in hospital. Sensitive anticipatory discussion is encouraged where possible, but usually this does not happen, despite the evidence suggesting that many older patients would like to be involved in such decisio...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.12067
更新日期：2013-04-01 00:00:00
abstract：:Paliperidone, the 9-hydroxy metabolite of risperidone, was approved on 20 December, 2006 by the US Food and Drug Administration for the treatment of schizophrenia. It is also being tested for the treatment of bipolar mania. An on-line query of http://www.pubmed.gov and http://www.clinicaltrials.gov for 'paliperidone' ...
journal_title：International journal of clinical practice
pub_type： 杂志文章,评审
doi：10.1111/j.1742-1241.2007.01321.x
更新日期：2007-04-01 00:00:00
abstract：:Patients with groin herniae do not always seek medical advice and, when listed for surgery, often wait many months for elective repair. We audited our emergency admissions for complicated groin herniae to establish whether a change in policy for elective surgery could lower their incidence. We performed a retrospectiv...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/j.1368-5031.2004.0097.x
更新日期：2004-02-01 00:00:00
abstract：AIMS:To examine the relationship between costs of hyperglycaemia drug treatment and glycemic control amongst people with type 2 diabetes (T2D). METHODS:This observational study utilised data from the QUALIDIAB database on 3,452 T2D patients seen in Diabetes Centers in Argentina. Patients were classified according to t...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：10.1111/ijcp.13336
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:DPP-4 inhibitors (DPP4-I) have been shown to provide non-inferior glycaemic control compared with sulfonylureas (SU), but result in a reduction of body weight and a significantly lower risk of hypoglycaemia in patients with type 2 diabetes. We aimed to validate these results in a large real-world sample of p...
journal_title：International journal of clinical practice
pub_type： 杂志文章,多中心研究
doi：10.1111/ijcp.12179
更新日期：2013-10-01 00:00:00
abstract：OBJECTIVE:To describe the efficacy and safety of asenapine for the treatment of schizophrenia and bipolar disorder. DATA SOURCES:The pivotal registration trials were accessed by querying http://www.pubmed.gov, http://www.fda.gov and http://www.clinicaltrials.govfor the search terms 'asenapine' or 'ORG 5222'. STUDY SE...
journal_title：International journal of clinical practice
pub_type： 杂志文章,meta分析,评审
doi：10.1111/j.1742-1241.2009.02228.x
更新日期：2009-12-01 00:00:00
abstract：:Respiratory physicians often encounter patients with chronic cough. The evaluation and outcome of such patients by centres with established diagnostic protocols has been well described. By contrast, little is known about patients referred to general respiratory clinics where no such protocol exists. We describe the fi...
journal_title：International journal of clinical practice
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
