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Mitral valve surgery in advanced heart failure.

Abstract：

:The appropriateness and timing of mitral valve surgery in patients with advanced heart failure and severe mitral regurgitation remains controversial. Recent surgical results provide evidence for beneficial effects on left ventricular remodeling and functional capacity. Given the absence of randomized trials comparing the outcomes of mitral valve surgery to medical therapy, however, clinical decision making regarding surgery for these fragile patients poses a dilemma to thoughtful clinicians. This paper reviews the pathophysiology of mitral regurgitation in heart failure and proposes an integrated approach to management.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

Di Salvo TG,Acker MA,Dec GW,Byrne JG

doi

10.1016/j.jacc.2009.08.059

subject

Has Abstract

pub_date

2010-01-26 00:00:00

pages

271-82

issue

4

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(09)03621-3

journal_volume

55

pub_type

杂志文章,评审

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