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Guillain-Barré syndrome as leading manifestation of graft-versus-host disease in an allogeneic bone marrow transplanted patient.

Abstract：

:Guillain-Barré Syndrome (GBS) is the most frequent cause of neuromuscular paralysis in industrialized countries and usually occurs after respiratory and gastrointestinal infections. However, in rare cases GBS is associated with Graft-versus-Host Disease (GvHD). In the present case we report on a female allogeneic bone marrow transplanted patient who developed GBS as a leading manifestation of GvHD subsequent to discontinuation of her immunosuppressive medication with cyclosporine. In contrast to former case reports both IVIg and plasma exchange failed while resumption of immunosuppressive medication improved the condition of the patient clearly.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Thöne J,Lamprecht S,Hohaus A,Erbguth F,Bickel A

doi

10.1016/j.jns.2010.01.020

subject

Has Abstract

pub_date

2010-05-15 00:00:00

pages

114-6

issue

1-2

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(10)00047-X

journal_volume

292

pub_type

杂志文章

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