Abstract:
PURPOSE:To describe the clinical and radiologic features of orbital involvement in craniofacial brown tumors and to compare the rate of brown tumors in primary and secondary hyperparathyroidism. METHODS:A retrospective hospital-based study of 115 patients with chronic kidney disease and secondary hyperparathyroidism and 34 with primary hyperparathyroidism was conducted. Laboratory results such as serum levels of alkaline phosphatase, calcium, phosphorus, and parathyroid hormone were recorded. Demographic data (age, sex, duration of disease) and image findings (bone scan scintigraphy, skull and long bone x-rays, CT) were also obtained. The main outcome measures were analysis of clinical, biochemical, and radiologic findings of all patients. RESULTS:Of the 115 patients with chronic kidney disease, 10 (8.7%) had brown tumors in different bones of the skeleton. Five patients had lesions in the craniofacial bones. The maxilla, mandible, maxillary sinus, and nasal cavity were the most affected sites. The orbit was involved in 2 patients with lesions arising in the maxillary and ethmoid sinuses. One patient had facial leontiasis. All patients with brown tumors had extremely high levels of parathyroid hormone (>1,000 pg/ml, normal values 10-69 pg/ml) and alkaline phosphatase (>400 U/l, normal values 65-300 U/l). The mean serum levels of phosphorus and calcium were not abnormal among the patients with brown tumors. Age and time of renal failure were similar for patients with and without brown tumors. Among the patients with primary hyperparathyroidism, only 2 (5.8%) had brown tumors, and in just 1, the lesion was localized in the craniofacial skeleton. A 2-tailed Z test applied to compare the proportion of occurrence of brown tumors in the 2 groups revealed that the difference at the 90% of confidence level was not significant. CONCLUSIONS:Brown tumors are equally found in secondary and primary hyperparathyroidism. Craniofacial brown tumors involve the orbit, usually because of the osteodystrophy process that involves the maxilla and paranasal sinuses. The lesions do not necessarily need to be excised and may regress spontaneously after the control of hyperparathyroidism.
journal_name
Ophthalmic Plast Reconstr Surgjournal_title
Ophthalmic plastic and reconstructive surgeryauthors
Cecchetti DF,Paula SA,Cruz AA,Lucca L Jr,Nogueira-Barbosa MH,Chahud F,Conti-Freitas LC,Melo CBdoi
10.1097/IOP.0b013e3181b8e3ecsubject
Has Abstractpub_date
2010-03-01 00:00:00pages
106-11issue
2eissn
0740-9303issn
1537-2677pii
00002341-201003000-00010journal_volume
26pub_type
杂志文章abstract:PURPOSE:To determine orbital tissue tension and orbital compartment compliance in normal patients. METHODS:An orbital manometer was designed to directly measure orbital tissue tension before, during, and after a 5-ml retrobulbar injection of anesthetic in patients undergoing ocular surgery. Tissue tension was recorded...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-199903000-00010
更新日期:1999-03-01 00:00:00
abstract:PURPOSE:To review and summarize the clinical features, presentations, diagnostic modalities, and management of ophthalmic manifestations of eosinophilic granulomatosis with polyangiitis (EGPA, formerly Churg-Strauss Syndrome). METHODS:A systematic PubMed search of all English articles on EGPA with ophthalmic involveme...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0000000000001202
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To identify what factors may predispose patients to exposure of porous anophthalmic implants and to determine the outcome of exposed porous implants. METHODS:Examination of pooled data obtained through a PubMed literature search of English-language publications from 1989 through 2004 using the key words enucle...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章,评审
doi:10.1097/01.iop.0000249432.18688.ee
更新日期:2007-01-01 00:00:00
abstract::This is the first known report of a relatively large postoperative pyogenic granuloma developing after a nonsutured transconjunctival blepharoplasty. Inflammation and separation or malapposition of the conjunctival wound edges probably permitted the lesion to proliferate in the inferior fornix. No foreign material cou...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-199312000-00013
更新日期:1993-12-01 00:00:00
abstract:PURPOSE:The programmed death-1 pathway negatively regulates the immune system. Previous reports have indicated worse tumor-related outcomes with increased expression of the ligand for this pathway. This study was undertaken to assess the role of the PD pathway in cutaneous malignancies that invade the orbit. METHODS:I...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0000000000000880
更新日期:2018-03-01 00:00:00
abstract::Displacement or extrusion of the standard glass Jones tube causes conjunctivodacryocystorhinostomy to fail in many cases. Patients who have had trauma, a tumor excised, or have received radiation therapy in the medial canthal area are particularly susceptible to this complication. Gladstone and Putterman developed a m...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-198909000-00007
更新日期:1989-01-01 00:00:00
abstract:PURPOSE:The authors report and evaluate their experience with an individualized approach to orbital exenteration. METHODS:Retrospective chart review was performed on a consecutive series of 25 orbital exenteration patients at a tertiary care center. The cases were classified into two groups for the retrospective analy...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/01.iop.0000066699.53489.88
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of silicone rod in tarsofrontalis sling surgery for severe congenital ptosis. METHODS:A prospective, case series study was performed in 46 patients (56 eyelids) who underwent tarsofrontalis sling surgery using silicone rod for severe congenital ptosis. The efficacy of the si...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0b013e3182a74f44
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:Vascular malformations of the conjunctiva are symptomatically distressing and surgically challenging. Because their expansive nature necessitates broad conjunctival sacrifice in some cases, epithelial reconstitution may be the best way to avoid symblepharon formation. Amniotic membrane grafts have been useful f...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0b013e3181b2f796
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:We compared bovine pericardium and homologous sclera as wrapping materials for hydroxyapatite (HA) ocular implants in enucleated New Zealand white rabbits. METHODS:Eighteen rabbits were unilaterally enucleated and the sockets implanted with 10-mm HA spherical implants. Six implants were wrapped with homologous...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-199909000-00003
更新日期:1999-09-01 00:00:00
abstract::The pathophysiologic mechanisms responsible for the clinical features of the anophthalmic socket are poorly understood. Atrophy of orbital fat has been thought to be a major contributing cause of enophthalmos and the superior sulcus deformities that develop after enucleation, but it has never been demonstrated histopa...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-199006000-00002
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:To evaluate current trends in the management of the anophthalmic socket after primary enucleation and evisceration. METHODS:The active membership of the American Society of Ophthalmic Plastic and Reconstructive Surgery (ASOPRS) was surveyed regarding primary enucleations and eviscerations performed between Jan...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/01.iop.0000129528.16938.1e
更新日期:2004-07-01 00:00:00
abstract::We report a case of a man who had undergone gold eyelid loading for lagophthalmos 22 years earlier. During examination for a complaint of foreign body sensation in the operated eye, the gold weight was found under the palpebral conjunctiva. Although extrusion of a gold weight through the skin anteriorly is well recogn...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/01.IOP.0000087032.75134.77
更新日期:2003-09-01 00:00:00
abstract:PURPOSE:The purpose of this study is to explore mechanical and co-innervational factors involved in both voluntary and involuntary brow elevation among people affected by ptosis and dermatochalasis. METHODS:In this prospective cohort study of normal controls and eyelids with ptosis or dermatochalasis, marginal reflex ...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0000000000001178
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:To compare the functional outcome of the polypropylene trapezoid frontalis suspension with the polypropylene modified Crawford frontalis suspension in a large cohort of patients with oculopharyngeal muscular dystrophy. METHODS:Retrospective, nonrandomized comparative case series. Patients with oculopharyngeal ...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0000000000000648
更新日期:2017-01-01 00:00:00
abstract::From 1950 through 1984, 123 patients underwent surgical treatment of blepharospasm at the Mayo Clinic. During this period, four different operations (proximal and distal neurectomy and two types of myectomy) were used. Significant recurrent or residual blepharospasm was observed more frequently (p less than 0.01) and ...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-198501040-00006
更新日期:1985-01-01 00:00:00
abstract:PURPOSE:Traditionally, eyelid skin incisions with electro-cautery devices have been avoided due to the concerns of aesthetically unacceptable scar formation. The purpose of this study is to compare ecchymosis, cosmesis, and histologic tissue damage of incisions made with a scalpel or Colorado needle in patients undergo...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/IOP.0000000000000820
更新日期:2017-11-01 00:00:00
abstract:PURPOSE:To analyze a new bioresorbable orbital implant (open-celled polylactic acid, also known as OPLA). METHODS:The implants were examined macroscopically, with chemical analysis (Fourier transform infrared spectroscopy), and microscopically with scanning electron microscopy. Animal implantation of OPLA implants was...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-200209000-00005
更新日期:2002-09-01 00:00:00
abstract:PURPOSE:To determine the prevalence of involutional entropion and ectropion of the lower eyelid in the elderly population; to examine how these disorders are related to gender, age, skin color, and axial ocular globe projection; and to define the incidence of associated ocular surface and pathologic eyelid findings. M...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0b013e3182115229
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To report our preliminary experience using hyaluronic acid gel fillers as a nonsurgical alternative in the management of congenital eyelid malpositions. METHODS:In this retrospective interventional case series, 5 patients (10 eyes) with congenital eyelid malpositions, including eyelid retraction, ectropion, eu...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0b013e3181ac984b
更新日期:2009-07-01 00:00:00
abstract:PURPOSE:Hydroxyapatite (HA) orbital implants are commonly used for the anophthalmic socket. With a HA implant, if motility is not satisfactory then a peg system can be surgically placed in attempts to improve motility. The authors report the technique and results of 83 patients who received motility peg placement over ...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0b013e3181b8c733
更新日期:2011-03-01 00:00:00
abstract::Traumatic blow-out fractures of the orbital floor are a common injury that can lead to significant morbidity. Accepted indications for surgical repair include displaced fractures consisting of a defect > 50% of the orbital floor, extraocular muscle entrapment, and clinically significant enophthalmos. Although infraorb...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-199412000-00010
更新日期:1994-12-01 00:00:00
abstract:PURPOSE:Amid the increasing clinical application of hyaluronic acid (HA) fillers in the ocular adnexa is a paucity of histological data concerning the fate of the injected material. The current study documents the in vivo biodegradation of HA deposited in the eyelid and orbit. METHODS:The study included 22 chinchilla ...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0000000000001374
更新日期:2019-11-01 00:00:00
abstract:PURPOSE:To describe a technique for localizing a lost rectus muscle during strabismus or retinal surgery or following trauma. METHODS:In this single center, retrospective chart review, 5 patients were identified between January 2012 and June 2016 with a lost rectus muscle; 3 during strabismus surgery and 2 post trauma...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0000000000000944
更新日期:2017-11-01 00:00:00
abstract:PURPOSE:To describe the use of an endovascular therapeutic technique in the management of a giant carotid cavernous aneurysm. METHODS:We reviewed the clinical and neuroradiologic findings of a patient with an unusual case of carotid cavernous aneurysm and intraorbital rupture. The medical literature was searched for s...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/00002341-200101000-00013
更新日期:2001-01-01 00:00:00
abstract::Sebaceous carcinoma of the eyelid is frequently misdiagnosed clinically and histopathologically. The tumor may present as a lid mass, recurrent chalazion, or diffuse unilateral blepharoconjunctivitis. Fifty percent of cases are misdiagnosed, often by an inexperienced general pathologist interpreting the initial biopsy...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章,评审
doi:10.1097/00002341-199103000-00008
更新日期:1991-01-01 00:00:00
abstract:PURPOSE:To determine the clinical efficacy of positron emission tomography (PET) in the treatment of patients with orbital malignancy. METHODS:Prospective, consecutive case series to assess the ability of PET to (1) identify lesions previously demonstrated on CT or MRI; (2) characterize the metabolic activity of these...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/01.iop.0000235493.82052.37
更新日期:2006-09-01 00:00:00
abstract:PURPOSE:To report the clinicopathologic features and management of patients with benign reactive lymphoid hyperplasia of the caruncle and plica semilunaris. METHODS:This retrospective case series includes 5 patients with lesions in the caruncle or plica semilunaris who underwent surgical excision over a 10-year period...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0b013e3181596b68
更新日期:2007-11-01 00:00:00
abstract::Silent sinus syndrome is a rare acquired condition that typically presents as enophthalmos and hypoglobus due to atelectasis of the maxillary sinus. The chronic negative pressure in the sinus slowly retracts the orbital floor, altering orbital anatomy and affecting the function of orbital contents. The authors present...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0b013e31827bda92
更新日期:2013-09-01 00:00:00
abstract::A 47-year-old women presented with a mass on the right medial canthal area for 10 years. On examination, an 18 × 12-mm sized, hard, unmovable subcutaneous mass was palpated. The tear meniscus was high, but the lacrimal outflow system was patent when irrigated. The mass was surgically excised. It was well-demarcated wi...
journal_title:Ophthalmic plastic and reconstructive surgery
pub_type: 杂志文章
doi:10.1097/IOP.0b013e3181e173c4
更新日期:2011-01-01 00:00:00