Abstract:
PURPOSE:A potential method to relieve the pain from medial osteoarthritis of the knee is to offload the medial compartment. The Latella™ Knee Implant is a novel device designed to offload the medial compartment. The objective of the Cotera-1 study was to evaluate the preliminary safety and feasibility of the Latella implant to treat patients with medial OA of the knee, by a 2-year follow-up of a prospective multicenter feasibility study (Cotera-1) performed in the Netherlands and UK METHODS: In this first-in-man study, 11 participants received the Latella implant and were followed for 2 years, documenting physician assessment, Patient-Reported Outcome (PRO) scoring (KOOS, IKDC, Kujala, SF-36); Patient Global Assessment (PGA), radiographic analysis and MRI analysis, complications, reoperation rate and hip-knee-ankle axis. RESULTS:The Latella Knee Implant system proved to be well tolerated and demonstrated a low-risk safety profile up to 24 months post-treatment. A responder analysis was performed of the subjects who still had the Latella implanted at 24-month time point (n = 9). Based on a MCID of eight for KOOS pain sub-scale, 78% of the subjects at the 24 month time point would be considered as responders. Similarly, based on improvement in the medial knee pain compared to baseline using the NRS scale of 1-10, 89% of the subjects at the 24-month time point would be considered as responders. Two patients were revised during follow-up: one for arthrofibrosis and one converted to TKA for progression of OA. CONCLUSIONS:The early clinical experience with the Latella Knee Implant in this pilot feasibility study has been encouraging. It appears to be a safe implant with possible effect on medial OA. Additional studies need to be performed to assess the safety and efficacy of the procedure in a larger patient population. LEVEL OF EVIDENCE:II.
journal_name
Arch Orthop Trauma Surgjournal_title
Archives of orthopaedic and trauma surgeryauthors
Haverkamp D,van der Vis HM,Lee J,Achan P,Sierevelt IN,Ramachandran Mdoi
10.1007/s00402-020-03390-xsubject
Has Abstractpub_date
2020-12-01 00:00:00pages
1873-1881issue
12eissn
0936-8051issn
1434-3916pii
10.1007/s00402-020-03390-xjournal_volume
140pub_type
杂志文章abstract:INTRODUCTION:Inferior survival of cemented total hip arthroplasty has been reported after previous femoral osteotomy. The purpose of this study was to evaluate the long-term survival of uncemented stems after femoral osteotomy. MATERIALS AND METHODS:Forty-eight hips in 45 patients had undergone conversion THA for a fa...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-005-0800-z
更新日期:2005-06-01 00:00:00
abstract::A follow-up after 2 years on average could be done in 43 cases of pelvic ring injuries. Seven were type A, 8 type B and 28 type C lesions. Every type A lesion was treated non-operatively. External fixation and non-operative management were used with type B injuries. As well as non-operative treatment, both internal an...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/BF00434095
更新日期:1997-01-01 00:00:00
abstract::The prophylactic effect of nonsteroid anti-inflammatory drugs on the recurrence of high-grade periarticular heterotopic ossification after resection was studied in ten patients operated on for loosening of one or both components of a cemented total hip prosthesis. These drugs, given at a standard dosage for 1-3 weeks ...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/BF00439378
更新日期:1990-01-01 00:00:00
abstract::Implantation of chondrosarcoma in the bones of the hands is an infrequent occurrence. We present two cases in which the fifth metacarpal and the proximal phalanx of the index finger, respectively, were affected in two patients aged 47 and 67 years, who, without previous known lesions, came to consultation on the appea...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/BF00572885
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The aim of this study was to investigate the potential of MRI to determine rotational alignment after TKA in comparison to the gold standard, CT. METHODS:Rotational alignment was measured in the transverse plane on CT and MR-images in 14 patients prior to TKA revision. Differences between CT and...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-015-2289-4
更新日期:2015-11-01 00:00:00
abstract:INTRODUCTION:The indication and treatment of malunited fractures of the distal radius in the growing skeleton differ from those for adults. The literature results are scarce. In this study we examined the results of surgical correction following fractures of the distal radius in infants. MATERIALS AND METHODS:Seven in...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-003-0585-x
更新日期:2004-01-01 00:00:00
abstract::Eight patients with delayed rupture of the extensor pollicis longus tendon are presented. Six had suffered from a fracture of the wrist without dislocation. This is in our opinion a predisposing factor in the etiology of delayed tendon rupture. Our treatment of choice is transfer of the extensor indicis proprius tendo...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/BF00441626
更新日期:1994-01-01 00:00:00
abstract::In a randomized double-blind study involving 42 postmenopausal women with a displaced Colles' fracture, we investigated whether piroxicam, a nonsteroid anti-inflammatory drug, can reduce posttraumatic osteopenia and improve the rate of recovery. In an earlier study [3] we found a bone-sparing effect caused by piroxica...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF00449987
更新日期:1993-01-01 00:00:00
abstract:INTRODUCTION:Mechanical complications, such as cut-out of the head-neck fixation device, are the most common causes of morbidity after trochanteric femur fracture treatment. The causes of cut-out complications are well defined in patients who are treated with sliding hip screws and biaxial cephalomedullary nails but th...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-016-2410-3
更新日期:2016-05-01 00:00:00
abstract:INTRODUCTION:Fragility fractures are a growing worldwide health care problem. Hip fractures have been clearly associated with poor outcomes. Fragility fractures of other bones are common reasons for hospital admission and short-term disability, but specific long-term outcome studies of non-hip fragility fractures are r...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-014-2115-4
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:We aimed to compare results of treatment of oblique-spiral metacarpal and phalangeal fractures with screw only or mini plate plus screw, respectively. METHODS:A total of 43 patients who were operated with a diagnosis of displaced, irreducible, unstable, rotational oblique-spiral metacarpal and proximal ph...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-015-2164-3
更新日期:2015-04-01 00:00:00
abstract::Rotational open wedge osteotomy was performed on 20 hips in 19 older patients with Perthes' disease with an extensive lesion. All subjects had little viable bone in the posterolateral epiphysis preoperatively. The repair process was observed radiographically until 1 year postoperatively. The patients' mean age at the ...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-002-0408-5
更新日期:2002-07-01 00:00:00
abstract::It is often not feasible to conduct large trials in orthopaedic surgery. Therefore, surgeons must identify strategies to optimize the statistical power of their smaller studies. The aim of this study was to compare study power in randomized trials with continuous versus dichotomous outcome variables. We performed a sy...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s004020100347
更新日期:2002-03-01 00:00:00
abstract::The authors present an experimental study of 30 rats, in which human dura mater preserved in glycerin was used to repair gaps in the Achilles tendon. The animals were killed 8 weeks after the surgery and evaluated by gross and microscopic examination. The results showed that the dura mater did not cause foreign-body r...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/BF00440572
更新日期:1990-01-01 00:00:00
abstract:INTRODUCTION:Two revisions of broken β-titanium total hip stems had to be performed in our hospital after 2 and 4 years in situ. Since both fractures were located at the level of a laser engraving, a failure analysis was conducted. MATERIALS AND METHODS:Both retrieved hip stems were disinfected and collected in our re...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-015-2225-7
更新日期:2015-07-01 00:00:00
abstract:INTRODUCTION:Management of humerus nonunions with previously failed fixation presents a complex problem. There are multiple revision fixation strategies, of which compression plating is a mainstay. The aim of this study was to assess the results of open reduction and direct compression plating without the need for auto...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-020-03577-2
更新日期:2020-10-29 00:00:00
abstract:INTRODUCTION:The treatment of fractures of the distal tibia can be problematical because of the thin soft-tissue covering. Bridging slide-insertion plate osteosynthesis is performed by indirect, axially correct reduction of the fracture and stabilization without opening the soft tissue at the fracture site. Stripping o...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-004-0778-y
更新日期:2005-03-01 00:00:00
abstract::The efficiency of prophylactic antibiotic therapy in amputation surgery was studied in a prospective, randomized trial of a first-generation cephalosporin (cephalothin) compared with a narrow-spectrum beta-lactam stable penicillin (methicillin). Eighty-eight patients received cephalothin 2 g X 4 on the day of operatio...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF00439382
更新日期:1990-01-01 00:00:00
abstract:INTRODUCTION:Restoring the joint line (JL) in primary as well as revision total knee arthroplasty (TKA) influences clinical results as well as long-term survival rates. Whereas studies agree about the negative effect of JL alteration, the reference system of choice is unclear. The purpose of the present study was to ev...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-014-1953-4
更新日期:2014-04-01 00:00:00
abstract::Although the iliac crest is the most common site from which autogenous bone grafts are obtained, complications are surprisingly rare. One of these is incisional hernia through the resulting bony defect. Occasionally, the herniated contents may proceed to obstruction or strangulation and require emergency surgery. Elec...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章,评审
doi:10.1007/BF00932452
更新日期:1989-01-01 00:00:00
abstract:HYPOTHESIS:Arthroscopic acromioclavicular joint (ACJ) resection for asymptomatic ACJ arthritis combined with rotator cuff repair leads to more satisfactory pain relief and decrease reoperation rate when inferiorly directed osteophytes present at the undersurface of ACJ. MATERIALS AND METHODS:Between January 2006 and M...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00402-010-1216-y
更新日期:2011-03-01 00:00:00
abstract:INTRODUCTION:The intraoperative estimation of the anteversion of the femoral component of a total hip arthroplasty is generally made by the surgeon's visual assessment of the stem position relative to the condylar plane of the femur. AIM:The aim of this study was to evaluate the femoral component anteversion relative ...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-011-1282-9
更新日期:2011-09-01 00:00:00
abstract:INTRODUCTION:The German national nosocomial infections surveillance system (KISS) has been collecting surveillance data from hip and knee prosthesis operations since 1997. The purpose of this article is to investigate whether surveillance and feedback of surgical site infection (SSI) information to the physicians and n...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-005-0036-y
更新日期:2005-10-01 00:00:00
abstract:INTRODUCTION:ACL reconstruction with either patellar tendon or semitendinosus tendon autografts are standard procedures. Between these two grafts might be differences in stability, morbidity, or long-term changes. This study investigates outcomes of ACL reconstruction with patellar tendon versus semitendinosus tendon a...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00402-015-2386-4
更新日期:2016-04-01 00:00:00
abstract::Four patients are presented who had closed femoral shaft fractures and developed either extensive callus or osteomyelitis following open Kuntscher nailing and cerclage wiring of a butterfly fragment. Both the Kuntscher nail and cerclage wire are made of stainless steel but with different percentages of constituent ele...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/BF00454737
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:The iliotibial band (ITB) is used in anterior cruciate ligament (ACL) reconstruction in skeletally immature patients as well as several other orthopedic reconstructions. The purpose of this study is to determine the size of the ITB as an autograft option in ACL reconstruction surgery or other orthopedic soft...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-019-03208-5
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:The purposes of this study were: (1) to compare tunnel locations using the conventional transtibial technique with reference data, and (2) to identify factors that make it difficult to position the femoral tunnel correctly or contribute to breakage of the bone bridge between the two tibial tunnels. MATERI...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-013-1780-z
更新日期:2013-08-01 00:00:00
abstract:INTRODUCTION:Starting from January 2009, we systematically irrigated the surgical wounds of patients undergoing spine surgery with a solution of povidone-iodine (PVP-I) and hydrogen peroxide (H(2)O(2)). METHOD:We prospectively recorded the clinical data of patients who underwent spine surgery during 2009 and we compar...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-011-1262-0
更新日期:2011-09-01 00:00:00
abstract:INTRODUCTION:The treatment of large full thickness cartilage defects with matrix guided autologous chondrocyte transplantation shows promising results. However, in many cases an arthrotomy is needed to implant the cell seeded scaffolds. Recently techniques have been developed for arthroscopically guided ACT implantatio...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-012-1477-8
更新日期:2012-06-01 00:00:00
abstract::This study quantifies changes in bone mineral density (BMD) in the opposite hip and in both proximal tibiae and the correlation with the use of walking aids for patients with two types of hip fracture during the 1st year after surgery. In all, 26 women and 15 men aged 42-88 years (median 71 years) were included. Twent...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s004020050291
更新日期:1998-01-01 00:00:00