当前位置： SCI文献检索 > Journal of Proteomics期刊下所有文献 > Mass spectrometry imaging for drugs and metabolites.

Mass spectrometry imaging for drugs and metabolites.

Abstract：

:Mass spectrometric imaging (MSI) is a powerful analytical technique that provides two- and three-dimensional spatial maps of multiple compounds in a single experiment. This technique has been routinely applied to protein, peptide, and lipid molecules with much less research reporting small molecule distributions, especially pharmaceutical drugs. This review's main focus is to provide readers with an up-to-date description of the substrates and compounds that have been analyzed for drug and metabolite composition using MSI technology. Additionally, ionization techniques, sample preparation, and instrumentation developments are discussed.

journal_name

J Proteomics

journal_title

Journal of proteomics

authors

Greer T,Sturm R,Li L

doi

10.1016/j.jprot.2011.03.032

subject

Has Abstract

pub_date

2011-11-18 00:00:00

pages

2617-31

issue

12

eissn

1874-3919

issn

1876-7737

pii

S1874-3919(11)00139-4

journal_volume

74

pub_type

杂志文章,评审

相关文献

Journal of Proteomics文献大全
  • Subcellular fractionation of stored red blood cells reveals a compartment-based protein carbonylation evolution.

    abstract：:During blood banking, erythrocytes undergo storage lesions, altering or degrading their metabolism, rheological properties, and protein content. Carbonylation is a hallmark of protein oxidative lesions, thus of red blood cell oxidative stress. In order to improve global erythrocyte protein carbonylation assessment, su...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2012.05.004

    authors： Delobel J,Prudent M,Rubin O,Crettaz D,Tissot JD,Lion N

    更新日期：2012-12-05 00:00:00

  • Validation of serum protein profiles by a dual antibody array approach.

    abstract：:In recent years, affinity-based technologies have become important tools for serum profiling to uncover protein expression patterns linked to disease state or therapeutic effects. In this study, we describe a path towards the production of an antibody microarray to allow protein profiling of biotinylated human serum s...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2009.09.009

    authors： Rimini R,Schwenk JM,Sundberg M,Sjöberg R,Klevebring D,Gry M,Uhlén M,Nilsson P

    更新日期：2009-12-01 00:00:00

  • GeLC-Orbitrap/MS and 2-DE-MALDI-TOF/TOF comparative proteomics analysis of seed cotyledons from the non-orthodox Quercus ilex tree species.

    abstract：:Gel electrophoresis-based and shotgun approaches are the most employed proteomic platforms in plant biology research, with the latter replacing the former in the last years. We have compared 2-DE-MALDI-TOF/TOF and GeLC-Orbitrap/MS analyses using the same protein extracts from Quercus ilex cotyledons at different devel...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2020.104087

    authors： Sghaier-Hammami B,Castillejo MÁ,Baazaoui N,Jorrín-Novo JV,Escandón M

    更新日期：2021-02-20 00:00:00

  • Proteomic analysis of Moroccan cobra Naja haje legionis venom using tandem mass spectrometry.

    abstract：UNLABELLED:The proteome of the venom of Naja haje legionis, the only medically important elapid species in Morocco, has been elucidated by using a combination of proteomic techniques that includes size exclusion chromatography, reverse-phase HPLC, Tricine/SDS-Page, tryptic digestion, Q-TOF tandem mass spectrometry and ...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2013.11.012

    authors： Malih I,Ahmad rusmili MR,Tee TY,Saile R,Ghalim N,Othman I

    更新日期：2014-01-16 00:00:00

  • Comparative proteomic analysis reveals differentially expressed proteins correlated with fuzz fiber initiation in diploid cotton (Gossypium arboreum L.).

    abstract：UNLABELLED:In this study, a comparative proteomic analysis was employed to identify fuzz fiber initiation-related proteins in wild-type diploid cotton (Gossypium arboreum L.) and its fuzzless mutant. Temporal changes in global proteomes were examined using 2-DE at five developmental time points for fuzz fiber initiatio...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2013.02.020

    authors： Du SJ,Dong CJ,Zhang B,Lai TF,Du XM,Liu JY

    更新日期：2013-04-26 00:00:00

  • Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress.

    abstract：:High content omic techniques in combination with stable human in vitro cell culture systems have the potential to improve on current pre-clinical safety regimes by providing detailed mechanistic information of altered cellular processes. Here we investigated the added benefit of integrating transcriptomics, proteomics...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2012.11.022

    authors： Wilmes A,Limonciel A,Aschauer L,Moenks K,Bielow C,Leonard MO,Hamon J,Carpi D,Ruzek S,Handler A,Schmal O,Herrgen K,Bellwon P,Burek C,Truisi GL,Hewitt P,Di Consiglio E,Testai E,Blaauboer BJ,Guillou C,Huber CG,Luka

    更新日期：2013-02-21 00:00:00

  • Tick salivary secretion as a source of antihemostatics.

    abstract：:Ticks are mostly obligatory blood feeding ectoparasites that have an impact on human and animal health. In addition to direct damage due to feeding, some tick species serve as the vectors for the causative agents of several diseases, such as the spirochetes of the genus Borrelia causing Lyme disease, the virus of tick...

    journal_title：Journal of proteomics

    pub_type： 杂志文章,评审

    doi：10.1016/j.jprot.2012.04.026

    authors： Chmelar J,Calvo E,Pedra JH,Francischetti IM,Kotsyfakis M

    更新日期：2012-07-16 00:00:00

  • A comparative study of the Se/S substitution in methionine and cysteine in Se-enriched yeast using an inductively coupled plasma mass spectrometry (ICP MS)-assisted proteomics approach.

    abstract：UNLABELLED:A proteomics approach based on 2D gel electrophoresis followed by HPLC-electrospray Orbitrap MS/MS was developed to investigate the replacement and the degree of the Se/S substitution in methionine and cysteine in Se-rich yeast. Capillary HPLC-inductively coupled plasma mass spectrometry (ICP-MS), employed i...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2013.05.010

    authors： Bierla K,Bianga J,Ouerdane L,Szpunar J,Yiannikouris A,Lobinski R

    更新日期：2013-07-11 00:00:00

  • Usage of electrostatic eliminator reduces human keratin contamination significantly in gel-based proteomics analysis.

    abstract：:In the field of bottom-up proteomics, heavy contamination of human keratins could hinder the comprehensive protein identification, especially for the detection of low abundance proteins. In this study, we examined the keratin contamination in the four major experimental procedures in gel-based proteomic analysis inclu...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2011.03.001

    authors： Xu B,Zhang Y,Zhao Z,Yoshida Y,Magdeldin S,Fujinaka H,Ismail TA,Yaoita E,Yamamoto T

    更新日期：2011-06-10 00:00:00

  • Venomics and antivenomics of Bothrops erythromelas from five geographic populations within the Caatinga ecoregion of northeastern Brazil.

    abstract：:The Caatinga lancehead, Bothrops erythromelas, is a medically relevant species, responsible for most of the snakebite accidents in most parts of its distribution range in northeastern Brazil. The spectrum and geographic variability of its venom toxins were investigated applying a venomics approach to venom pools from ...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2014.11.011

    authors： Jorge RJ,Monteiro HS,Gonçalves-Machado L,Guarnieri MC,Ximenes RM,Borges-Nojosa DM,Luna KP,Zingali RB,Corrêa-Netto C,Gutiérrez JM,Sanz L,Calvete JJ,Pla D

    更新日期：2015-01-30 00:00:00

  • A phosphoproteomic study reveals shp-1 cleavage reprograms LPS signaling via a PI-3K/NF-κB and mTORC1 related mechanism.

    abstract：:The reprogrammed lipopolysaccharide (LPS) pathway has been reported to render patients more susceptible to the development of post-traumatic multiple organ dysfunction syndrome (MODS). To facilitate thorough understanding of this mechanism, a phosphoproteomic study was utilized to screen the potential signaling molecu...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2015.07.003

    authors： Xu E,Chen J,Wang Y,Ke Z,Luo S,Zou Z

    更新日期：2015-10-14 00:00:00

  • Proteome characterization of small extracellular vesicles from spared nerve injury model of neuropathic pain.

    abstract：:Exosomes are 30-150 nm extracellular vesicles mediating intercellular communication. Disease states can alter exosome composition affecting the message carried and thereby, its functional impact. The objective of this study was to identify proteins present in these vesicles in a mouse model of neuropathic pain induced...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2019.103540

    authors： Jean-Toussaint R,Tian Y,Chaudhuri AD,Haughey NJ,Sacan A,Ajit SK

    更新日期：2020-01-16 00:00:00

  • Comparative iTRAQ proteomics revealed proteins associated with spermatogenic arrest of cattleyak.

    abstract：UNLABELLED:Male infertility of cattleyak due to spermatogenic arrest greatly restricts their effective utilization in yak breeding. Although much work has been done to investigate the mechanisms of spermatogenic arrest, there is no information regarding the differences of protein composition between cattleyak and yak t...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2016.04.049

    authors： Yu S,Cai X,Sun L,Zuo Z,Mipam T,Cao S,Shen L,Ren Z,Chen X,Yang F,Deng J,Ma X,Wang Y

    更新日期：2016-06-16 00:00:00

  • Comparative proteomic and physiological analyses reveal the protective effect of exogenous calcium on the germinating soybean response to salt stress.

    abstract：:Calcium enhances salt stress tolerance of soybeans. Nevertheless, the molecular mechanism of calcium's involvement in resistance to salt stress is unclear. A comparative proteomic approach was used to investigate protein profiles in germinating soybeans under NaCl-CaCl2 and NaCl-LaCl3 treatments. A total of 80 protein...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2014.09.023

    authors： Yin Y,Yang R,Han Y,Gu Z

    更新日期：2015-01-15 00:00:00

  • Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.

    abstract：:Deposition of calcium oxalate (CaOx) crystals in renal interstitium is one of the key factors that cause progressive inflammation in kidney stone disease. Macrophages are responsible for elimination of these crystals but their roles to worsen inflammatory process remain under-investigated. This study thus aimed to def...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2018.06.015

    authors： Singhto N,Thongboonkerd V

    更新日期：2018-08-15 00:00:00

  • Protein profiling identified dissociations between growth hormone-mediated longitudinal growth and bone mineralization in short prepubertal children.

    abstract：:Growth hormone (GH) promotes longitudinal growth and bone mineralization. In this study, a proteomic approach was used to analyze the association between serum protein expression pattern and height-adjusted bone mineralization in short prepubertal children receiving GH treatment. Patterns of protein expression were co...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2010.08.007

    authors： Andersson B,Decker R,Nierop AF,Bosaeus I,Albertsson-Wikland K,Hellgren G

    更新日期：2011-01-01 00:00:00

  • Design and expression of a QconCAT protein to validate Hi3 protein quantification of influenza vaccine antigens.

    abstract：UNLABELLED:Quantification of the antigens hemagglutinin and neuraminidase in influenza vaccines has been reported using an antibody-free liquid chromatography-mass spectrometry (LC-MS) based method known as MS(E) "Hi3". This approach is based on the average signal intensity of the three most intense tryptic peptides re...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2016.06.024

    authors： Smith DG,Gingras G,Aubin Y,Cyr TD

    更新日期：2016-09-02 00:00:00

  • Quantitative proteomics using tandem mass tags in relation to the acute phase protein response in chicken challenged with Escherichia coli lipopolysaccharide endotoxin.

    abstract：:The inflammatory response in chickens (Gallus Gallus domesticus) is an integral part of the bird's response to infection. Detailing proteomic changes occurring during infection would be beneficial to the poultry industry, offering opportunities for comparative pathophysiological analysis. The objective of this study w...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2018.08.009

    authors： Horvatić A,Guillemin N,Kaab H,McKeegan D,O'Reilly E,Bain M,Kuleš J,Eckersall PD

    更新日期：2019-02-10 00:00:00

  • Direct characterization of target podocyte antigens and auto-antibodies in human membranous glomerulonephritis: Alfa-enolase and borderline antigens.

    abstract：:The identification of glomerular auto-antigens in idiopathic human membranous glomerulonephritis (MGN) is a crucial step towards the definition of the mechanisms of the disease. Recent 'in vivo' studies demonstrated a heterogeneous composition of glomerular immune-deposits in MGN biopsies only a part of which have bee...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2011.05.021

    authors： Bruschi M,Carnevali ML,Murtas C,Candiano G,Petretto A,Prunotto M,Gatti R,Argentiero L,Magistroni R,Garibotto G,Scolari F,Ravani P,Gesualdo L,Allegri L,Ghiggeri GM

    更新日期：2011-09-06 00:00:00

  • Oral administration of Bifidobacterium longum CECT 7347 modulates jejunal proteome in an in vivo gliadin-induced enteropathy animal model.

    abstract：:Celiac disease is an immune-mediated disorder triggered by gluten proteins of wheat (gliadins) and other cereals. Gliadin-mediated effects on weanling animals, sensitized or not with interferon (IFN)-γ, were investigated. Also, the influence of the co-administration of Bifidobacterium longum CECT 7347 was studied toge...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2012.09.005

    authors： Olivares M,Laparra M,Sanz Y

    更新日期：2012-12-21 00:00:00

  • Proteomic investigation of whole saliva in Wilson's disease.

    abstract：:Wilson's disease is a rare inherited disorder of copper metabolism, manifesting hepatic, neurological and psychiatric symptoms. Early diagnosis is often unfeasible and a unique diagnostic test is currently inapplicable. We performed the qualitative/quantitative characterization of the salivary proteome/peptidome of 32...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2015.07.033

    authors： Cabras T,Sanna M,Manconi B,Fanni D,Demelia L,Sorbello O,Iavarone F,Castagnola M,Faa G,Messana I

    更新日期：2015-10-14 00:00:00

  • Protein composition of the outermost exosporium-like layer of Clostridium difficile 630 spores.

    abstract：UNLABELLED:Clostridium difficile spores are considered the morphotype of infection, transmission and persistence of C. difficile infections. There is a lack of information on the composition of the outermost exosporium layer of C. difficile spores. Using recently developed exosporium removal methods combined with MS/MS...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2015.03.035

    authors： Díaz-González F,Milano M,Olguin-Araneda V,Pizarro-Cerda J,Castro-Córdova P,Tzeng SC,Maier CS,Sarker MR,Paredes-Sabja D

    更新日期：2015-06-18 00:00:00

  • The Trypanosoma rangeli trypomastigote surfaceome reveals novel proteins and targets for specific diagnosis.

    abstract：UNLABELLED:Sympatric distribution and sharing of hosts and antigens by Trypanosoma rangeli and Trypanosoma cruzi, the etiological agent of Chagas' disease, often incur in misdiagnosis and improper epidemiological inferences. Many secreted and surface proteins (SP) have been described as important antigens shared by the...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2013.02.011

    authors： Wagner G,Eiko Yamanaka L,Moura H,Denardin Lückemeyer D,Schlindwein AD,Hermes Stoco P,Bunselmeyer Ferreira H,Robert Barr J,Steindel M,Grisard EC

    更新日期：2013-04-26 00:00:00

  • Love me tender: an Omics window on the bovine meat tenderness network.

    abstract：:Meat tenderness prediction is a challenging task, especially in Maremmana, an Italian autochtonous and highly appreciated beef breed. In the present study we reported an integrated proteomics, phosphoproteomics and metabolomics overview of meat tenderness in longissimus dorsi from 15 male Maremmana individuals, throug...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2012.02.013

    authors： D'Alessandro A,Rinalducci S,Marrocco C,Zolla V,Napolitano F,Zolla L

    更新日期：2012-07-19 00:00:00

  • Charting the cellular and extracellular proteome analysis of Brevibacterium linens DSM 20158 with unsequenced genome by mass spectrometry-driven sequence similarity searches.

    abstract：UNLABELLED:Brevibacterium linens DSM 20158 is an industrially important actinobacterium which is well-known for the production of amino acids and enzymes. However, as this strain has an unsequenced genome, there is no detailed information regarding its proteome although another strain of this microbe, BL2, has a shotgu...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2013.02.029

    authors： Shabbiri K,Botting CH,Adnan A,Fuszard M

    更新日期：2013-05-27 00:00:00

  • Targeted mass spectrometry for Serum Amyloid A (SAA) isoform profiling in sequential blood samples from experimentally Staphylococcus aureus infected pigs.

    abstract：:Serum amyloid A (SAA) is a well-described acute phase protein induced during the acute phase response (APR) to infection. Four isoform specific genes are found in most mammals. Depending on species, SAA3 and SAA4 are generally preferentially expressed extrahepatically whereas SAA1 and SAA2 are hepatic isoforms dominat...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2020.103904

    authors： Leuchsenring AB,Karlsson C,Bundgaard L,Malmström J,Heegaard PMH

    更新日期：2020-09-15 00:00:00

  • Differential proteomics analysis to identify proteins and pathways associated with male sterility of soybean using iTRAQ-based strategy.

    abstract：UNLABELLED:To further elucidate the molecular mechanism of cytoplasmic male sterility (CMS) in soybean, a differential proteomic analysis was completed between the CMS line NJCMS1A and its maintainer NJCMS1B using iTRAQ-based strategy. As a result, 180 differential abundance proteins (DAPs) were identified, of which, 6...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2016.02.017

    authors： Li J,Ding X,Han S,He T,Zhang H,Yang L,Yang S,Gai J

    更新日期：2016-04-14 00:00:00

  • Profiling of local disease-sparing responses to bovine respiratory syncytial virus in intranasally vaccinated and challenged calves.

    abstract：:Bovine and human respiratory syncytial viruses (BRSV, HRSV) are primary causes of pneumonia in calves and children respectively, with vaccination offering protection via antibody and cellular immune responses. However, with no vaccines currently licensed for human use, evaluation of local responses to BRSV vaccination...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2019.103397

    authors： Gray D,Ellis JA,Gow SP,Lacoste SR,Allan GM,Mooney MH

    更新日期：2019-07-30 00:00:00

  • The identification and characterization of epitopes in the 30-34 kDa Trypanosoma cruzi proteins recognized by antibodies in the serum samples of chagasic patients.

    abstract：:Trypanosoma cruzi proteins with molecular weight between 30 and 34 kDa have shown high reactivity in western blot assays with serum samples from chagasic individuals. However, in-depth analysis of the constituents of these protein fractions has not been performed. This is the first report of an immunoaffinity proteomi...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2012.11.001

    authors： Verissimo da Costa GC,Lery LM,da Silva ML,Moura H,Peralta RH,von Krüger WM,Bisch PM,Barr JR,Peralta JM

    更新日期：2013-03-27 00:00:00

  • Nuclear proteome analysis reveals a role of Vav1 in modulating RNA processing during maturation of tumoral promyelocytes.

    abstract：:Vav1 is a key molecule in the ATRA-induced acquisition of a mature phenotype by tumoral myeloid precursors. Since ATRA acts throughout events that require extensive changes of nuclear architecture and activity and considering that Vav1 accumulates inside the nuclear compartment of differentiating APL-derived cells, th...

    journal_title：Journal of proteomics

    pub_type： 杂志文章

    doi：10.1016/j.jprot.2011.08.005

    authors： Bertagnolo V,Grassilli S,Petretto A,Lambertini E,Astati L,Bruschi M,Brugnoli F,Nika E,Candiano G,Piva R,Capitani S

    更新日期：2011-12-21 00:00:00